EBI Dbfetch

ID   AF030336; SV 1; linear; mRNA; STD; INV; 1494 BP.
XX
AC   AF030336;
XX
DT   15-NOV-1997 (Rel. 53, Created)
DT   15-APR-2005 (Rel. 83, Last updated, Version 3)
XX
DE   Schistosoma mansoni tyrosine hydroxylase (TH) mRNA, complete cds.
XX
KW   .
XX
OS   Schistosoma mansoni
OC   Eukaryota; Metazoa; Platyhelminthes; Trematoda; Digenea; Strigeidida;
OC   Schistosomatoidea; Schistosomatidae; Schistosoma.
XX
RN   [1]
RP   1-1494
RX   PUBMED; 9751167.
RA   Hamdan F.F., Ribeiro P.;
RT   "Cloning and characterization of a novel form of tyrosine hydroxylase from
RT   the human parasite, Schistosoma mansoni";
RL   J. Neurochem. 71(4):1369-1380(1998).
XX
RN   [2]
RP   1-1494
RA   Hamdan F.F., Ribeiro P.;
RT   ;
RL   Submitted (19-OCT-1997) to the EMBL/GenBank/DDBJ databases.
RL   Parasitology, McGill University, 21,111 Lakeshore Rd., MacDonald Campus,
RL   Institute of Parasitology, Ste. Anne De Bellevue, Quebec H9X 3V9, Canada
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1494
FT                   /organism="Schistosoma mansoni"
FT                   /strain="Puerto Rican"
FT                   /mol_type="mRNA"
FT                   /db_xref="taxon:6183"
FT   CDS             42..1439
FT                   /codon_start=1
FT                   /gene="TH"
FT                   /product="tyrosine hydroxylase"
FT                   /function="catalyzes the rate limiting step in
FT                   catecholamine synthesis"
FT                   /EC_number="1.14.16.2"
FT                   /db_xref="GOA:O17446"
FT                   /db_xref="HSSP:1TOH"
FT                   /db_xref="InterPro:IPR019773"
FT                   /db_xref="UniProtKB/Swiss-Prot:O17446"
FT                   /protein_id="AAC62256.1"
FT                   /translation="MKMTMMCDESIEENNKSSTVELNHNEKDGRIHSIIINFHPITHEQ
FT                   SNNQFYIQTLHEILKYIIDKKLNLVHFETRPTLTLSNANRDVQYSCLITLEANEINMSL
FT                   LYEELRGNSFISGINLLNNQESEDWYPKHISDLDKCQHLLRKFQPELQTDHPGFHDKVY
FT                   RERREAIAKIAFQYKYGDRIPEVEYTKEEIETWGLVFTKMKAVHASRACREYIDGFQLL
FT                   EKYCNYNSESIPQLQTICEFMHRTSGFRIRPVAGLVSPKDFLASLAFRVFQCTQYIRHH
FT                   SRPMHTPEPDCIHELIGHMPMLVNRQFADFSQELGLASLGASEEEITRLSTLYWFTVEF
FT                   GLCNENGETRALGAGIMSSYGELENAFSDLSVKEPFNINDAAVQVYDDVGYQKIYFVTE
FT                   SIESMKRELRNYINTSGKSTIPIYDPITETVHMKSRFSIRKELLKHVKEEIGQLDTLLN
FT                   HSNYTLP"
XX
SQ   Sequence 1494 BP; 544 A; 231 C; 251 G; 468 T; 0 other;
     ttttatttta tgagagggct tatcttaaat ctaaggacta aatgaagatg acaatgatgt        60
     gtgacgaaag catcgaggaa aataacaaat cttcaactgt tgaattaaat cataatgaaa       120
     aggacggtag gatacattca attattatta attttcatcc aataactcat gaacaatcta       180
     ataatcagtt ttatatacaa actttacatg aaatattgaa atatataatt gacaagaaat       240
     tgaatcttgt acactttgaa acgagaccaa ctttgacttt atccaatgcc aatcgagacg       300
     ttcaatattc ttgtttaata actttggaag caaatgaaat aaatatgagt ttattgtacg       360
     aagaattacg gggcaacagt tttatttcag gaataaattt actaaataat caggaatctg       420
     aagattggta tcctaagcac atttctgatt tggataaatg tcaacaccta ctacgtaaat       480
     ttcaacctga attacaaact gatcatccag gatttcatga caaagtctac agagagcgac       540
     gagaagccat agcgaaaata gcatttcaat acaaatatgg tgatcgtata cctgaagttg       600
     aatatactaa agaagaaatt gaaacttggg gcttggtttt cacaaaaatg aaagctgtcc       660
     atgcttcaag agcatgcaga gaatatattg atggatttca gctcttagaa aaatattgta       720
     attacaattc tgaaagcata ccccaactgc aaacaatctg cgaatttatg catcgtactt       780
     caggatttcg tattcgacct gttgctggtt tagtttcacc aaaagatttc ttggcaagct       840
     tagcgtttag agtatttcaa tgtactcaat atatacgtca tcattcacgt cctatgcata       900
     caccagaacc ggattgcatt cacgaactca ttggtcatat gcctatgtta gtaaatagac       960
     aatttgctga cttttctcaa gaactaggtt tagcatcttt aggagcttcc gaagaagaaa      1020
     ttacgaggct atcaacatta tactggttta ctgttgaatt tggtttatgt aatgaaaatg      1080
     gtgaaacacg tgcattaggt gctggaatta tgtcatcata tggtgaattg gaaaatgcat      1140
     ttagtgatct ctctgtgaaa gaaccattta atataaatga tgcggcagta caagtatacg      1200
     atgatgttgg ttatcaaaaa atttactttg taactgaatc tattgaatca atgaaacgtg      1260
     aacttcgaaa ctacataaat acgtctggaa aatcaacaat tccaatttac gatccaatca      1320
     cagaaacagt gcatatgaaa tctagatttt ctattcgaaa agaacttctg aaacatgtga      1380
     aagaagagat tggtcagttg gatacattgc ttaatcattc taattataca ttaccatgaa      1440
     aaattattca ggatatataa tctatgtcat taatttatca agtaaaaaca cagt            1494
//