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EBI DbfetchID AF019759; SV 1; linear; mRNA; STD; MAM; 2199 BP. XX AC AF019759; XX DT 29-SEP-1997 (Rel. 52, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 4) XX DE Canis familiaris beta-glucuronidase (GUSB) mRNA, complete cds. XX KW . XX OS Canis lupus familiaris (dog) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis. XX RN [1] RP 1-2199 RX DOI; 10.1006/geno.1997.5189 RX PUBMED; 9521879. RA Ray J., Bouvet A., DeSanto C., Fyfe J.C., Xu D., Wolfe J.H., Aguirre G.D., RA Patterson D.F., Haskins M.E., Henthorn P.S.; RT "Cloning of the canine beta-glucuronidase cDNA, mutation identification in RT canine MPS VII, and retroviral vector-mediated correction of MPS VII RT cells"; RL Genomics 48(2):248-253(1998). XX RN [2] RP 1-2199 RA Henthorn P.S., Fyfe J.C., Bouvet A.B.; RT ; RL Submitted (15-AUG-1997) to the EMBL/GenBank/DDBJ databases. RL Section of Medical Genetics, University of Pennsylvania School of RL Veterinary Medicine, 3900 Delancey St., Philadelphia, PA 19104, USA XX FH Key Location/Qualifiers FH FT source 1..2199 FT /organism="Canis lupus familiaris" FT /mol_type="mRNA" FT /db_xref="taxon:9615" FT CDS 63..2018 FT /codon_start=1 FT /gene="GUSB" FT /product="beta-glucuronidase" FT /EC_number="3.2.1.31" FT /note="lysosomal enzyme" FT /db_xref="GOA:O18835" FT /db_xref="HSSP:1BHG" FT /db_xref="InterPro:IPR006102" FT /db_xref="UniProtKB/Swiss-Prot:O18835" FT /protein_id="AAC48809.1" FT /translation="MSRGPAGAWVALGPLLWTCGLALEGGMLYPRESPSRERKDLDGLW FT SFRADFSDGRRQGFEQQWYRAPLRESGPTLDMPVPSSFNDVGQDRQLRSFVGWVWYERE FT ATLPRRWSQDPGTRVVLRIGSAHYYAIVWVNGVHVAEHEGGHLPFEADISKLVQSGPLS FT SCRITLAINNTLTPHTLPPGTIVYKTDASKYPKGYFVQNTYFDFFNYAGLHRPVLLYTT FT PTTYIDDITVTTGVDQDTGLVDYQIFVQGSEHFQLEVYLLDEEGKVVAQGTGSQGRLQV FT PNVHLWWPYLMHEHPAYLYSLEVRLTAQMAAGPVSDFYTLPVGIRTVAVTERQFLINGK FT PFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQLCDRYG FT IVVIDESPGVGIMLVQSYSNVSLQHHLEVMGELVRRDKNHPSVVMWSVANEPTSFLKPA FT AYYFKTLIAHTKALDPSRPVTFVTNSNYEADLGAPYVDVICVNSYYSWYHDYGHMEVIQ FT LQLATEFENWYRTYQKPIIQSEYGAETIAGFHQDPPLMFSEEYQKGLLEQYHLVLDQKR FT KEYVVGELIWNFADFMTDQSPQRAVGNRKGIFTRQRQPKAAAFLLRERYWKLANETGHH FT RSAAKSQCLENSPFAL" XX SQ Sequence 2199 BP; 457 A; 639 C; 668 G; 435 T; 0 other; cggggctgcg ggctgcgggc tgcgggctgc gcgccggggc cacgcgcggc cgcgacggaa 60 gcatgtctcg ggggccggcg ggggcctggg tagcgctcgg cccgctgctt tggacctgcg 120 ggctggcgct ggagggcggg atgctgtacc cccgggagag cccgtcgcgg gagcgcaagg 180 acctcgacgg cctctggagc ttccgcgccg acttctccga cggccggcgc cagggcttcg 240 agcagcagtg gtaccgggcg ccgctgcgcg agtcgggccc caccctggac atgccagttc 300 cgtccagctt caatgatgtg ggccaggata ggcagctgcg cagctttgtc ggctgggtgt 360 ggtacgagcg ggaggccacc ctgccccggc gatggagcca ggacccgggc acgagagtgg 420 tgctgaggat tggcagcgcc cactactatg ccatcgtgtg ggtgaatggg gtccatgtgg 480 cagagcacga ggggggtcac ctccccttcg aagctgacat cagcaagttg gtccagagcg 540 ggcccctgtc ctcctgccgt attacccttg ccatcaacaa cacgctcacc ccccacactc 600 tgccgccagg gaccatcgtc tacaagacag acgcttccaa gtaccccaag ggttacttcg 660 tccagaacac atactttgac ttcttcaact acgcgggcct gcatcgccct gtgctcctct 720 acaccacacc tactacctac atcgacgaca tcaccgtcac caccggcgtg gaccaagaca 780 ctgggctggt ggattaccag atttttgtcc agggcagtga acacttccag ctggaagtgt 840 atcttctgga tgaggaaggc aaggtcgtgg cccaggggac agggagccag ggccggctgc 900 aggtgcccaa tgtccacctc tggtggccgt acctgatgca tgagcacccc gcctacctgt 960 actcgttgga ggtgaggctg actgcgcaga tggccgctgg gcctgtgtca gacttctata 1020 ctctccccgt ggggattcgc accgtggccg tcacagagcg ccagttcctc atcaacggga 1080 aacctttcta tttccatggg gtcaacaaac atgaggatgc cgatatccga gggaagggct 1140 ttgactggcc gctgctggtg aaggacttca acctgttgcg ctggctgggc gccaatgcct 1200 tccgcaccag ccactacccc tacgcggagg aggtgatgca gctctgcgac cgctatggga 1260 tcgtggtcat cgacgagagc cctggtgtgg gcatcatgct ggtccagagc tacagcaatg 1320 tgtccctgca gcaccatctg gaggtgatgg gggagctggt gcgtcgggat aagaatcacc 1380 catctgtagt catgtggtct gtagccaatg agcccacttc cttcctgaag cctgctgctt 1440 actacttcaa gacgctgatt gctcacacca aggccttgga cccctcccgg cccgtgacct 1500 ttgtgaccaa ttccaactat gaagcagacc tgggggcgcc gtatgtggac gtcatctgtg 1560 tcaacagtta ctactcttgg tatcacgact atgggcacat ggaggtgatt cagctgcagc 1620 tggccaccga gtttgagaac tggtatagga cctaccagaa accaataatc cagagcgagt 1680 acggggcaga gacaattgca ggcttccacc aggatccacc tctgatgttc agtgaggagt 1740 accagaaagg tctgctcgag cagtatcact tggtgctgga tcagaaacgc aaagaatatg 1800 tggttggaga gctcatctgg aattttgctg attttatgac tgaccagtca ccacagagag 1860 cagtagggaa cagaaagggc atcttcactc gccagagaca acccaaagcg gcggccttcc 1920 ttttgcgaga gaggtactgg aaacttgcca atgaaaccgg gcaccaccgg tccgcggcca 1980 agtcccagtg tttggaaaac agcccgttcg ccctctgaag cctctgtctg ccccggaggg 2040 gaagggacca cgtccacgga ccccatggac cgcgtgtggc cgcctgggac gttcctgcct 2100 gcagcctgta ctgattcact ggaagggaat cttagaggtg gaaataaagg cttttgttgt 2160 gtgtgaataa agagtcatct tagaaaaaaa aaaaaaaaa 2199 // |
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