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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AF019415; SV 1; linear; genomic DNA; STD; HUM; 1759 BP.
XX
AC   AF019415;
XX
DT   04-DEC-1998 (Rel. 57, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 4)
XX
DE   Homo sapiens homeodomain protein (Nkx2.2) gene, exon 2 and complete cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-1759
RX   PUBMED; 9703340.
RA   Furuta H., Horikawa Y., Iwasaki N., Hara M., Sussel L., Le Beau M.M.,
RA   Davis E.M., Ogata M., Iwamoto Y., German M.S., Bell G.I.;
RT   "Beta-cell transcription factors and diabetes: mutations in the coding
RT   region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not
RT   associated with maturity-onset diabetes of the young in Japanese";
RL   Diabetes 47(8):1356-1358(1998).
XX
RN   [2]
RP   1-1759
RA   Furuta H., Horikawa Y., Bell G.I.;
RT   ;
RL   Submitted (14-AUG-1997) to the EMBL/GenBank/DDBJ databases.
RL   Howard Hughes Medical Institute, The University of Chicago, 5841 S.
RL   Maryland Avenue, MC1028, Chicago, IL 60637, USA
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1759
FT                   /organism="Homo sapiens"
FT                   /chromosome="20"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:9606"
FT   mRNA            join(AF019414.1:1..364,346..1759)
FT                   /gene="Nkx2.2"
FT                   /product="homeodomain protein"
FT   gene            order(AF019414.1:1..576,1..1759)
FT                   /gene="Nkx2.2"
FT   CDS             join(AF019414.1:106..364,346..908)
FT                   /codon_start=1
FT                   /gene="Nkx2.2"
FT                   /product="homeodomain protein"
FT                   /note="transcription factor"
FT                   /db_xref="GDB:132589"
FT                   /db_xref="GOA:O95096"
FT                   /db_xref="HGNC:7835"
FT                   /db_xref="InterPro:IPR001356"
FT                   /db_xref="InterPro:IPR009057"
FT                   /db_xref="InterPro:IPR012287"
FT                   /db_xref="InterPro:IPR017970"
FT                   /db_xref="InterPro:IPR020479"
FT                   /db_xref="UniProtKB/Swiss-Prot:O95096"
FT                   /protein_id="AAC83132.1"
FT                   /translation="MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRA
FT                   GPLGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSP
FT                   EPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLAS
FT                   LIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQD
FT                   LAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW"
FT   exon            346..1759
FT                   /gene="Nkx2.2"
FT                   /number=2
XX
SQ   Sequence 1759 BP; 341 A; 552 C; 478 G; 388 T; 0 other;
     tgcccacgtc tcgccggaga ggaaaccgct taagggcgcc ggagccctta acccgcgatg        60
     atcttcagtg ccacttcccc ccccaaattc tcacccacac tatgtgagcc ccttgaaagg       120
     cgagccccta gcccccactc ctacggattt ccctctttac cctgggaggt cccgacgtct       180
     tcgtcaggcg tagaggaagg caggggtcat ggcaaaggca gcggggctgg gctgccaggc       240
     gcggaggtcc agggtcgcac ggaggatcca gggtgctccg agtctggtgc aggctgcgcg       300
     cggcctccag acgcctgacg cgcttctctc tccccctccc cccagtgcac ggtctggctg       360
     ccggggcgcc ccctcaggac tcaagctcca agtccccgga gccctcggcc gacgagtcac       420
     cggacaatga caaggagacc ccgggcggcg ggggggacgc cggcaagaag cgaaagcggc       480
     gagtgctttt ctccaaggcg cagacctacg agctggagcg gcgctttcgg cagcagcggt       540
     acctgtcggc gcccgagcgc gaacacctgg ccagcctcat ccgcctcacg cccacgcagg       600
     tcaagatctg gttccagaac caccgctaca agatgaagcg cgcccgggcc gagaaaggta       660
     tggaggtgac gcccctgccc tcgccgcgcc gggtggccgt gcccgtcttg gtcagggacg       720
     gcaaaccatg tcacgcgctc aaagcccagg acctggcagc cgccaccttc caggcgggca       780
     ttcccttttc tgcctacagc gcgcagtcgc tgcagcacat gcagtacaac gcccagtaca       840
     gctcggccag caccccccag tacccgacag cacaccccct ggtccaggcc cagcagtgga       900
     cttggtgagc gccgccccaa cgagactcgc ggccccaggc ccaggcccca ccccggcggc       960
     ggtggcggcg aggaggcctc ggtccttatg gtggttatta ttattattat aattattatt      1020
     atggagtcga gttgactctc ggctccacta gggaggcgcc gggaggttgc ctgcgtctcc      1080
     ttggagtggc agattccacc cacccagctc tgcccatgcc tctccttctg aaccttggga      1140
     gagggctgaa ctctacgccg tgtttacaga atgtttgcgc agcttcgctt ctttgcctct      1200
     ccccgggggg accaaaccgt cccagcgtta atgtcgtcac ttgaaaacga gaaaaagacc      1260
     gaccccccac ccctgctttc gtgcattttg taaaatatgt ttgtgtgagt agcgatattg      1320
     tcagccgtct tctaaagcaa gtggagaaca ctttaaaaat acagagaatt tcttcctttt      1380
     tttaaaaaaa aataagaaaa tgctaaatat ttatggccat gtaaacgttc tgacaactgg      1440
     tggcagattt cgcttttcgt tgtaaatatc ggtggtgatt gttgccaaaa tgaccttcag      1500
     gaccggcctg tttcccgtct gggtccaact cctttctttg tggcttgttt gggtttgttt      1560
     tttgttttgt ttttgttttt gcgttttccc ctgctttctt cctttctctt tttattttat      1620
     tgtgcaaaca tttctcaaat atggaaaaga aaaccctgta ggcagggagc cctctgccct      1680
     gtcctccggg ccttcagccc cgaacttgga gctcagctat tcggcgcggt tccccaacag      1740
     cgccgggcgc agaaagctt                                                   1759
//
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