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EBI DbfetchID AF019375; SV 1; linear; genomic DNA; STD; PRO; 13952 BP. XX AC AF019375; XX DT 15-MAY-1998 (Rel. 55, Created) DT 23-AUG-2007 (Rel. 92, Last updated, Version 5) XX DE Escherichia coli strain F632 LPS core biosynthesis region including DE heptosyl I transferase (waaC) gene, partial cds; lipid A-core:surface DE polymer ligase (waaL), GlcNAc transferase (waaK), WaaZ (waaZ), WaaY (waaY), DE UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase (waaR), DE UDP-glucose:(glucosyl) LPS alpha1,3-glucosyltransferase (waaO), DE UDP-galactose:(glucosyl) LPS alpha1,6-galactosyltransferase (waaB), WaaS DE (waaS), WaaP (waaP), UDP-glucose:(heptosyl) LPS DE alpha1,3-glucosyltransferase (waaG), and WaaQ (waaQ) genes, complete cds; DE and Kdo transferase (waaA) gene, partial cds. XX KW . XX OS Escherichia coli OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Escherichia. XX RN [1] RP 1-13952 RX DOI; 10.1074/jbc.273.15.8849 RX PUBMED; 9535865. RA Heinrichs D.E., Monteiro M.A., Perry M.B., Whitfield C.; RT "The assembly system for the lipopolysaccharide R2 core-type of Escherichia RT coli is a hybrid of those found in Escherichia coli K-12 and Salmonella RT enterica. Structure and function of the R2 WaaK and WaaL homologs"; RL J. Biol. Chem. 273(15):8849-8859(1998). XX RN [2] RP 1-13952 RX DOI; 10.1046/j.1365-2958.1998.01063.x RX PUBMED; 9791168. RA Heinrichs D.E., Yethon J.A., Whitfield C.; RT "Molecular basis for structural diversity in the core regions of the RT lipopolysaccharides of Escherichia coli and Salmonella enterica"; RL Mol. Microbiol. 30(2):221-232(1998). XX RN [3] RP 1-13952 RA Heinrichs D.E., Whitfield C.; RT ; RL Submitted (14-AUG-1997) to the EMBL/GenBank/DDBJ databases. RL Microbiology, University of Guelph, Guelph, ON N1G 2W1, Canada XX FH Key Location/Qualifiers FH FT source 1..13952 FT /organism="Escherichia coli" FT /strain="F632" FT /mol_type="genomic DNA" FT /note="R2 LPS core type representative" FT /db_xref="taxon:562" FT CDS <1..892 FT /codon_start=2 FT /transl_table=11 FT /gene="waaC" FT /product="heptosyl I transferase" FT /note="WaaC; similar to E. coli RfaC encoded by GenBank FT Accession Number U00039" FT /db_xref="GOA:O68199" FT /db_xref="InterPro:IPR011908" FT /db_xref="UniProtKB/TrEMBL:O68199" FT /protein_id="AAC69647.1" FT /translation="DAQQAIPGIKFDWVVEEGFAQIPSWHAAVERVIPVAIRRWRKAWF FT SAPIKAERKAFREALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAREPLASL FT FYNRKHHIAKQQHAVERIRELFAKSLGYSKPQTQGDYAIAQHFLTNLPTDAGEYAVFLH FT ATTRDDKHWPEEHWRELIGLLADSGIRIKLPWGAPHEEKRAKRLAEGFAYVEVLPKMSL FT EGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGKNQVVCRAPDKD FT LAHLTAETVFNKINS" FT CDS 931..2148 FT /codon_start=1 FT /transl_table=11 FT /gene="waaL" FT /product="lipid A-core:surface polymer ligase" FT /note="WaaL; similar to E. coli RfaL encoded by GenBank FT Accession Number U00039" FT /db_xref="GOA:O68200" FT /db_xref="InterPro:IPR007016" FT /db_xref="UniProtKB/TrEMBL:O68200" FT /protein_id="AAC69648.1" FT /translation="MLTASLALRNKEKWKPYWNKALVFLFIATFFLDGITRYKHIISIL FT MIITVIYQVSRAPGTFKVLYKNNLFYSVLALSLILLYATFISPDLKISFKEFSNTVLKG FT FLAYSLLIPALLKDEDNESIGKIVLYSLVTGLGLRCLVELILYIQDYNKGIMPFSTYEH FT RSISDSMVFLFPALLNLWLIKKTSYKIAFVIFSAVFLFLLLGTLSRGAWLAVFIVTLLW FT LILNRQWKLLMLTSIVISVAAVGVFTYKGDHAGKDRLIYKLQQTDSSYRYTNGTQGTAW FT TLIMENPLKGYGYGDDIYHAIYNKRVVDFPSWKFRQSIGPHNVVLSIWFAAGLAGLLAL FT LYLYGSIIKETANATFKTVVVTPYNGQLLLFLTLVSFYIIRGNFEEVDLKPIGLIVGLL FT LAMRNK" FT CDS complement(2202..3344) FT /codon_start=1 FT /transl_table=11 FT /gene="waaK" FT /product="GlcNAc transferase" FT /note="WaaK; similar to E. coli RfaK encoded by GenBank FT Accession Number U00039" FT /db_xref="GOA:O68201" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:O68201" FT /protein_id="AAC69649.1" FT /translation="MIKKIIFTVTPIFSIPPKGAAAVETWIYQVAKRLSIPVTIACIRN FT EGYPTYTKVNDHCDIHYIGFSRVYKRLFQKWTRLDPVPYSQRILNTQPKNTDPKDSVIV FT IHNSMKLYKQIRSRSPHAQLVMHLHNAFEPGELDKNAKIIVPSQFLFDFYSEKMPDANI FT AIVPNGFCSESYEQNNTEDLRQKLNIDANDTVLLFAGRISPDKGCLMLMEAFNQLNKIQ FT DNLKLVIVGDPFASKKGEKVEYQKKVLDAAKAIGAQCIMAGGQPPEQMHNYYRLADLVV FT VPSQVEEAFCMVAVEAMAAGKPVLASQKGGISEFVLEGITGYHLAEPMTSESILADIKR FT VLADADRAQIAKNARNFVFSKYSWEHVTQRFEAQIQDWFG" FT CDS complement(3397..4206) FT /codon_start=1 FT /transl_table=11 FT /gene="waaZ" FT /product="WaaZ" FT /note="function unknown; similar to E. coli RfaZ encoded by FT GenBank Accession Number U00039" FT /db_xref="UniProtKB/TrEMBL:O68202" FT /protein_id="AAC69650.1" FT /translation="MKNIRYIDKKDVENLIESKTSDDVIIFLSGPTSQKTPLSVLQTRD FT VIAVNGSAQYLLSHNIIPYIYVLTDVRFLHQRRDDFYKFSQRSRYTIVNVDVYEHASEE FT DKRYILQNCLVLRSFYRREKGGLIKKIKFNILSRIHKELLISVPFSKKGRLVGFCKDIN FT LGYCSCHTVAFAAIQIAYSLKYARIICSGLDLTGSCSRFYDEDKNPMPSELTRDLFKIL FT PFFRFMRENIEDINIYNLSDDTAIQYDIIPYMKISEIEEPCVYEKIS" FT CDS complement(4278..4976) FT /codon_start=1 FT /transl_table=11 FT /gene="waaY" FT /product="WaaY" FT /note="function unknown; similar to E. coli RfaY encoded by FT GenBank Accession Number U00039" FT /db_xref="GOA:O68203" FT /db_xref="InterPro:IPR009330" FT /db_xref="UniProtKB/TrEMBL:O68203" FT /protein_id="AAC69651.1" FT /translation="MIQKNKIKDLVVFTDENNSKYLNVLNDFLSYDINIIKVFRSIDDT FT KVMLIDTDYGKLILKVFSPKVKRNERFFKSLLKGDYYERLFEHTQKVRNEGLHSLNDFY FT LLAERKTLRFVHTYIMLIEYIDGVELCDIPDIDETLKNKIQQSIRSLHEHGMVSGDPHR FT GNFIIENGEVRIIDLSGKRASAQRKAKDRIDLERHYGIKNEVKDLGYYLLVYRKKIRNL FT MRRLKGKPAR" FT CDS complement(4994..6010) FT /codon_start=1 FT /transl_table=11 FT /gene="waaR" FT /product="UDP-glucose:(glucosyl) LPS FT alpha1,2-glucosyltransferase" FT /note="similar to E. coli RfaJ encoded by GenBank Accession FT Number U00039" FT /db_xref="GOA:O68204" FT /db_xref="InterPro:IPR002495" FT /db_xref="UniProtKB/TrEMBL:O68204" FT /protein_id="AAC69652.1" FT /translation="MNSFPAIEIDKVKAWDFRLIDENTAESLNVAYGVDSNYLDGVGVS FT ITSIVINNRHVNLDFYIIVDVYNDDFFQKVEKLAEQYQLRITLYRINTDNLQCLPCTQV FT WSRAMYFRLFAFQLLGVTLNRLLYLDADVVCKGNISQLLHLEFNGAVAAVVRDVDPMQE FT KAVVRLSDPELRGQYFNSGVVYLDLKKWTEAKLTEKALSILMSKDSIYKYPDQDVMNVL FT LKGMTIFLPREFNTIYTIKSELKDKTHQKYKELIKEDTLLIHYTGATKPWHKWAIYPSV FT KYYKIALERSPWKDDSPRDAKSIIEFKKRYKHLLVQHHYISGLIAGVCYLCRKYYRK" FT CDS complement(6174..7193) FT /codon_start=1 FT /transl_table=11 FT /gene="waaO" FT /product="UDP-glucose:(glucosyl) LPS FT alpha1,3-glucosyltransferase" FT /note="WaaO; similar to E. coli RfaI encoded by GenBank FT Accession Number U00039" FT /db_xref="GOA:O68205" FT /db_xref="InterPro:IPR002495" FT /db_xref="UniProtKB/TrEMBL:O68205" FT /protein_id="AAC69653.1" FT /translation="MQQVFFQETEFLNSVIDYNHKIEAENLCLDIAYGTDKNFLFGCGI FT SIASILKYNEGNQLCFHIFTDYFGDDDRKYFDALARQYKTRIKIYLINGDRLRSLPCTK FT NWTHAIYFRFVIADYFFNKAPKVLYLDADIICQGTIEPLINYTFSEHTVAMVVTEGQKD FT WWAKRAHSLGVAGIANGYFNSGFLLINTNQWTNERVSARAIAMLSDPEIVKKITHPDQD FT VLNMLLADKLVYADIKYNTQFSLNYQLKESFKNPVTNDTVFIHYIGPTKPWHDWAWDYP FT ISQAFMAAKNASPWKDTALLKPVNSNQLRYSAKHMLKKKQYIKGFGNYLLYFIKKLKH" FT CDS complement(7193..8272) FT /codon_start=1 FT /transl_table=11 FT /gene="waaB" FT /product="UDP-galactose:(glucosyl) LPS FT alpha1,6-galactosyltransferase" FT /note="WaaB; similar to E. coli RfaB encoded by GenBank FT Accession Number U00039" FT /db_xref="GOA:O68206" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:O68206" FT /protein_id="AAC69654.1" FT /translation="MKIAFIGEAVSGFGGMETVIRDVITTFRQQHIQSEIFFFCRNDKM FT DKGWLEGIKYSCSFSNIRLGFLRRAKHIHALSKWLHDYQPDVVICIDVISCLYAAKARK FT KSGIDVPVFSWPHFSLDHKKHAEYITCADYHLAISSGIKQQMISRGVPESTINVIFNPV FT EAKNSVIPAPGEGETATFIYVGRMKFEGQKRVKDLLDGLSQVQGNWKLHVLGDGSDFEK FT CQAYGRGLNIDDRIVWYGWQQHPWKLVQQDIKKVSALLLTSSFEGFPMTLLEALSWGIP FT CISADCVSGPVDIIQPDVNGHLYQPGDMTGFVALLNKYIAGEIHIAHEKIPASIDKFYQ FT PKYYDRLQKIIISVISRRK" FT CDS complement(8286..9158) FT /codon_start=1 FT /transl_table=11 FT /gene="waaS" FT /product="WaaS" FT /note="function unknown" FT /db_xref="GOA:O68207" FT /db_xref="HSSP:1G9R" FT /db_xref="InterPro:IPR002495" FT /db_xref="UniProtKB/TrEMBL:O68207" FT /protein_id="AAC69655.1" FT /translation="MPAGVALYSIISNNRHINLHFHLLISGIEEKECSAFYELEGPNTS FT ISVYYITDKFDINPDTLVLGIPLSTCLRFLIPEVIDDKINKILYLDCDVICNGPLDELV FT DYNLNADIACVIPDSPEMQERVKKLDYGIEFINYFNAGVMFINTSEWKKNNITQKALEM FT INSGKVYRYADQDVLNILLNGRVHYLDKKYNNKTTLSVRCDEEQKNLPNTIIMHYVTQN FT KPWYKIFRAQNFDHYFSNSPWKNHKRNLAPSSSEIRLKSKVFWLEGKYCKAISYYYKYL FT LVKLFGLKI" FT CDS complement(9299..10096) FT /codon_start=1 FT /transl_table=11 FT /gene="waaP" FT /product="WaaP" FT /note="similar to E. coli RfaP encoded by GenBank Accession FT Number U00039" FT /db_xref="GOA:O68208" FT /db_xref="InterPro:IPR017172" FT /db_xref="UniProtKB/TrEMBL:O68208" FT /protein_id="AAC69656.1" FT /translation="MVELEEPLATLWRGKDAFAEVKKLNGEVFRELETRRTLRFELAGK FT SYFLKWHKGTTLKEIIKNLLSLRMPVLGADREWHAIHRLHDVGVDTMHGIGFGEKGLNP FT LTRTSFIITEDLTPTISLEDYCADWAVNPPDVHIKRMLIARVATMVRKMHAAGINHRDC FT YICHFLLHLPFTGREDELKISVIDLHRAQIRAKVPRRWRDKDLIGLYFSSMNIGLTQRD FT IWRFMKVYFGMPLRDIYRLEIDLLKKARIKAGKIEARTIRKNL" FT CDS complement(10089..11213) FT /codon_start=1 FT /transl_table=11 FT /gene="waaG" FT /product="UDP-glucose:(heptosyl) LPS FT alpha1,3-glucosyltransferase" FT /note="WaaG; similar to E. coli RfaG encoded by GenBank FT Accession Number U00039" FT /db_xref="GOA:O68209" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:O68209" FT /protein_id="AAC69657.1" FT /translation="MIVAFCLYKYFPFGGLQRDFMRIASTVAARGHHVRVYTQSWEGDC FT PEAFELIRVPVKSHTNHGRNAEYYAWVQNHLKAHPADRVVGFNKMPGLDVYFAADVCYA FT EKVAQEKGFFYRLTSRYRHYAAFERATFEHGKSTKLMMLTDKQIADFQKHYQTEPERFQ FT ILPPGIYPDRKYNAQIPNSREIYRQKNGITEQQNLLLQVGSDFGRKGVDRSIEALASLP FT ESLRHNTLLFVVGQDKPRKFEVLAEKLGVRSKVHFFSGRNDVSELMAAADLLMHPAYQE FT AAGIVLLEAIAAGLPVLTTAVCGYAHYITDANCGTVIAEPFSQEQLNDVLRKALTQSPL FT RMAWAENARYYADTQDLYSLPEKAADIITGGLDG" FT CDS complement(11210..12244) FT /codon_start=1 FT /transl_table=11 FT /gene="waaQ" FT /product="WaaQ" FT /note="function unknown; similar to E. coli RfaQ encoded by FT GenBank Accession Number U00039" FT /db_xref="GOA:O68210" FT /db_xref="InterPro:IPR011916" FT /db_xref="UniProtKB/TrEMBL:O68210" FT /protein_id="AAC69658.1" FT /translation="MRYHGDMLLTTPVISTLKQNYPDAKIDMLLYQDTIPILSENPEIN FT ALYGISNKGTGTFDKIKNALSLIKTLRANNYDLVINLTDQWMVALLVRCLPARMKISQL FT YGHRQHGIWKKSFTHLAPIHGTHIVERNLSVLEPLGITDFYTETTMSYAEDCWKKMRQE FT LDALGVKDHYVVIQPTARQIFKCWDNDKFSMVIDALQHRGYQVVLTCGPSADDLACVDE FT IARGCQTKPITGLAGKTRFPELGALIDHAVLFIGVDSAPGHIAAAVKTPVISLFGATDH FT VFWRPWTENIIQFWAGNYQKMPTRHELDRNKKYLSVIPAEDVIAATEKLLPEDAPSADR FT NAQL" FT CDS 12687..>13952 FT /codon_start=1 FT /transl_table=11 FT /gene="waaA" FT /product="Kdo transferase" FT /note="WaaA; similar to E. coli KdtA encoded by GenBank FT Accession Number U00039" FT /db_xref="GOA:O68211" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:O68211" FT /protein_id="AAC69659.1" FT /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRHP FT LKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQHV FT YLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSAAGY FT AKLGKFVRRLLRRITLIAAQNEEDGARFVALSAKNNQVTVTGSLKFDISVTPQLAAKAV FT TLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPDAINLV FT RQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGHNPLEAA FT AHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLVKEVSSLLTDADYRSFYGRHAV FT EVLYQNQGALQRLLQLLEPYLPP" XX SQ Sequence 13952 BP; 4142 A; 2916 C; 2647 G; 4247 T; 0 other; tgatgcccag caggcaatcc cagggattaa gtttgactgg gtggtggaag aagggttcgc 60 acagattcct tcctggcacg ccgccgttga gcgagttatt cctgtggcaa tacgtcgctg 120 gcgtaaagcc tggttctcgg cccccataaa agctgaacgc aaagcgtttc gtgaagcgct 180 acaagcagag aactatgacg cagttatcga tgctcagggg ctggtaaaaa gcgcggcgct 240 ggtgacgcgt ctggcgcatg gcgtaaagca tggaatggac tggcaaaccg ctcgcgaacc 300 tttagccagc ctgttttaca atcgtaaaca tcatattgca aaacagcagc acgccgtaga 360 acgcatccgc gaactttttg ccaaaagtct gggctatagc aaaccgcaaa cccagggcga 420 ttatgctatc gcacagcatt ttctgacgaa cctgcctaca gatgctggcg aatatgccgt 480 atttcttcat gcgacgaccc gtgatgataa acactggccg gaagaacact ggcgagaatt 540 gattggttta ctggcagatt cagggattcg cattaaactt ccgtggggtg cgccgcatga 600 ggaaaaacgg gcgaaacgac tggcggaagg atttgcttat gttgaagtat tgccgaagat 660 gagtctggaa ggtgttgccc gtgtgctggc cggagcgaaa ttcgtggtat cggtagacac 720 tgggttaagt catttaactg cagcactgga tcgaccgaat atcacggttt atggaccaac 780 cgatccggga ttaattggcg gatatgggaa gaatcaggtg gtttgtaggg caccagataa 840 agatcttgct catctgactg cagaaacggt atttaataaa atcaattcct gattaatacg 900 ttatatatta tttaagatgg tggagaagca atgttaacag cctcgctggc gctacgtaat 960 aaagaaaagt ggaaaccgta ctggaataaa gcgttggtat tcctctttat tgcaaccttt 1020 ttccttgatg gtataacccg ttataaacac atcatatcta tactaatgat tattacggta 1080 atctatcaag tttctcgtgc tccgggaaca tttaaagtac tctataaaaa taatcttttt 1140 tatagtgtcc tggcactatc actcattctt ttatatgcta cttttatatc acctgatctg 1200 aaaatcagtt ttaaagaatt cagtaatacg gtacttaaag gatttttggc ctatagttta 1260 cttatacctg cattattaaa agatgaagat aatgaaagca ttggtaaaat tgtactatac 1320 tcattagtta ccggacttgg cttacgttgt cttgttgaac ttattcttta tattcaggat 1380 tataataaag gaataatgcc attttccacc tatgaacacc gtagtatttc cgattcaatg 1440 gtgtttctgt ttccagcatt attaaacctt tggcttatca agaaaacctc ttataaaata 1500 gcattcgtaa tttttagtgc agttttctta tttctgctat taggaacgct gtctcgtggt 1560 gcatggctgg cagtattcat agtgactctg ctatggttaa tcttaaatcg tcagtggaaa 1620 ttattgatgc tgacttccat cgttatttct gttgccgcag tgggtgtatt tacctataaa 1680 ggtgatcatg ctggtaaaga caggcttatt tataaacttc aacagaccga cagttcttat 1740 cgctatacca atggtactca aggtacggcg tggacattaa ttatggaaaa tcctcttaag 1800 ggatatggct acggcgatga tatttaccat gcaatatata ataagcgtgt tgtagatttt 1860 ccgtcatgga agttcaggca atccattggg ccacacaacg ttgttttgtc aatttggttt 1920 gcagcgggtt tggctggact actcgcttta ctttatctgt atggctctat tatcaaagag 1980 acagctaatg caacgtttaa aacagttgtc gtcactcctt ataatggtca attactacta 2040 tttttaacgc ttgtaagctt ttatattatt cgaggtaact tcgaggaagt tgatctcaaa 2100 ccaattggct tgattgttgg tttactgtta gcaatgcgga ataaataaaa aaaagcctgc 2160 ctgacattaa gttcaggcag gctcttcaaa tccaataatt tttaaccaaa ccagtcttgt 2220 atttgtgctt caaaacgctg agtaacatgt tcccagctat attttgagaa aacaaaattt 2280 cgggcatttt tagcaatttg agctctgtca gcatccgcca aaacgcgctt aatatccgcg 2340 agaatacttt cagatgtcat aggctctgca aggtgatagc ctgtaattcc ttccagaaca 2400 aactcactaa ttccaccttt ttgactggca agcactggtt tacctgccgc catcgcttca 2460 acagctacca tacaaaaagc ttcttctacc tgagaaggaa caacaactaa atctgctaaa 2520 cggtaatagt tatgcatctg ctctggaggc tgtccacccg ccataatgca ttgcgctcca 2580 atagctttcg ctgcatccag aacttttttc tgatattcaa ctttttcgcc ttttttactg 2640 gcaaaaggat ctccgacaat caccagtttg aggttatctt gtatcttatt cagctgatta 2700 aaagcctcca taagcatcag gcaaccttta tctggtgata tccttcctgc aaataataac 2760 acggtatcat ttgcatcaat gttcagtttc tgcctcaaat cttcagtatt attttgttca 2820 tacgattcag aacaaaaacc attaggcaca atagcaatat ttgcatcagg cattttttcc 2880 gaatagaaat cgaaaagaaa ctggctagga acaattatct ttgcattttt gtctaactca 2940 cctggctcga aagcattatg aagatgcata actagctgcg cgtgagggct tctgctacga 3000 atctgtttat acagcttcat gctattgtgg ataacaataa cagagtcttt cggatcagtg 3060 tttttaggtt gggtatttaa aatacgctga gaatatggca caggatcaag tcgagtccac 3120 ttttggaaaa gtcgtttata gactcgacta aaaccaatgt agtgaatatc acagtgatca 3180 tttacttttg tgtaggttgg gtaaccttcg tttcgaatac aggcgatagt tactggaatc 3240 gaaagtcttt ttgcgacctg ataaatccat gtttcaaccg ctgcagctcc ttttggcggt 3300 atagaaaata ttggtgtgac ggtaaatatt atttttttaa tcattattag ccaactccaa 3360 tataatttat aacacgtaat aaacacatat aaaatattag cttatttttt cataaacaca 3420 cggctcttca atttcggata ttttcatata gggaataata tcatattgaa ttgcagtatc 3480 gtcggataaa ttataaatat tgatatcttc tatattttca cgcataaaac ggaaaaatgg 3540 taaaattttg aataaatccc gagtcaactc tgagggcata ggattcttat cttcatcata 3600 gaaacgcgaa cagctacccg ttaaatcaag gcctgaacag ataatacgag catacttcag 3660 cgaataggct atttggattg cagcaaaagc aacggtatgg catgaacaat aaccgaggtt 3720 aatatccttg caaaagccaa ccagacgacc ttttttagaa aaaggtacag agatcaggag 3780 ctctttatga attcggctca aaatattaaa cttgatcttc ttgatcaatc cacctttttc 3840 tctgcggtaa aatgaacgta gtaccaggca gttttgaagg atgtaccgct tatcttcttc 3900 agaagcatgt tcataaacgt caacatttac gatggtataa cgacttctct ggctaaattt 3960 ataaaaatca tcacgccgtt gatgtaaaaa gcgaacatcg gtaagtacat aaatataggg 4020 aataatatta tgacttaata gatattgtgc agaaccattg acagcaataa catcccttgt 4080 ctgcagcact gacaatggtg ttttttgcga tgtggggccg gaaagaaaaa taataacatc 4140 atcagacgtt ttactttcta tcaggttttc aacatctttt ttgtcaatgt atctaatatt 4200 cttcatgata aacctgtgaa ataagaactc cgcatagaaa tgtcctgacg aagacgttta 4260 aatgtaagac ttttacttta tcgtgctggc ttccctttca aacgccgcat aagattacgt 4320 atttttttac gataaactaa aagataataa ccgagatctt taacctcatt cttaatacca 4380 taatgtcgct ctaaatcaat acgatctttc gctttacgtt gtgcagatgc ccgttttcct 4440 gaaagatcaa taatgcgtac ttcaccattt tcaataataa aattaccgcg gtgaggatca 4500 ccagatacca taccgtgttc gtgtaatgaa cgaattgatt gttgaatttt attttttaaa 4560 gtttcatcaa tatcggggat atcacacaac tctacgccat cgatatattc gataagcatg 4620 atataagtat ggacaaaacg taatgttttc cgttctgcca acaaataaaa atcattgaga 4680 gaatgtagcc cctcgttacg cactttttga gtatgctcaa aaaggcgttc ataataatct 4740 ccctttaaaa gagatttaaa gaaacgttcg ttgcgtttta ctttaggcga aaaaacttta 4800 agtatcaatt taccgtaatc ggtatcaata agcatgactt ttgtatcatc tatagaacga 4860 aaaactttga tgatattaat atcataagaa agaaagtcat ttaatacatt gagatacttt 4920 gagttatttt catcggtaaa aacaactaaa tctttgattt tattcttctg aatcatgtta 4980 aaccagttaa atgttattta cggtaatatt ttcggcaaag ataacacact cctgcaatga 5040 gtcctgagat ataatgatgt tgcactaaca gatgtttata tctttttttg aattcaataa 5100 ttgattttgc atctcgtggt gagtcatctt tccaggggga tctttctaaa gctattttat 5160 agtattttac cgatggataa attgcccatt tgtgccacgg cttggtggcc ccagtataat 5220 gaataagaag agtatcctct tttatcaact ctttatattt ttgatgcgtt ttatctttta 5280 actcactttt tattgtatat atagtattga actcacgtgg caggaatatt gtcatccctt 5340 ttagtaggac attcataacg tcctggtcag gatacttata aatactatct ttactcataa 5400 gaatagacag tgctttttcg gttagttttg cttctgtcca tttttttagg tctaagtaaa 5460 cgacaccaga attaaaatac tgcccccgaa gttcaggatc agataatctg actaccgcct 5520 tttcctgcat tgggtctaca tccctgacta ctgcagccac cgctccatta aactctaaat 5580 gcaatagttg actaatattt cccttacaaa ctacatcggc atcaagataa agcaaacgat 5640 taagtgttac tcccaataat tgaaaagcaa ataaacggaa gtacattgct cttgaccaga 5700 cttgtgtaca aggcaggcac tgaagattat cagtatttat tctataaagt gtgattctta 5760 attggtattg ctcagcaagt ttctcaactt tttgaaagaa atcgtcgtta taaacatcaa 5820 caataatata aaaatcaaga ttaacatgtc gattattaat gacaattgaa gtaatggaaa 5880 cacctacacc atcaagataa ttggaatcga caccataggc aacatttaaa ctttcagcag 5940 tattttcatc aataagccta aaatcccagg ctttaacttt atctatctct atggcaggaa 6000 atgagttcac aaggctatcc ttatatcatt actttatata ctcgttatac ttcaagttgc 6060 atgtgctgca tcggcgagtt actcggcatt tcagggccaa cgcaagcgtt cctcaaaacg 6120 ccactggctt tttgtcctgc aactcgaatt atttagagta tagattatca gtattaatgc 6180 tttagctttt ttataaaata caaaagatag ttgccaaatc ctttgatata ttgctttttt 6240 ttcaacatat gtttagcact gtatcttaat tgattactat taaccggttt caataacgca 6300 gtatccttcc atggtgaagc attttttgcc gccataaaag cttgtgatat tggataatcc 6360 caggcccagt catgccaggg tttagttgga ccaatataat gaataaaaac tgtatcgtta 6420 gttactgggt ttttaaaact ttcttttagt tgataattta aactaaactg agtgttatat 6480 ttaatatcag cataaacaag tttgtctgcc aataacatat ttaatacatc ctgatcagga 6540 tgtgttattt ttttgactat ctctggatca cttaacattg caatggcccg tgcagaaacc 6600 cgctcattcg tccattgatt agtattaatc agtaaaaaac cggagttaaa gtaaccatta 6660 gcaatcccag caacacctaa cgaatgagca cgttttgccc accagtcttt ttgtccttct 6720 gtaacaacca ttgcgactgt atgttcagaa aacgtgtaat tgataagtgg ttctatagtt 6780 ccctgacaaa taatatctgc atccagataa agaactttgg gtgctttatt aaaaaagtaa 6840 tcggcgataa caaaacgaaa ataaatagca tgagtccagt tcttggtgca gggtaatgaa 6900 cggagtcgat caccattaat taaatatatc ttaattcttg ttttatattg cctggccagg 6960 gcatcaaaat atttgcgatc gtcatcaccg aaataatcag taaaaatatg aaagcataat 7020 tgatttcctt cattatattt taatattgaa gcaatcgata ttccgcatcc aaaaagaaaa 7080 tttttgtcag tcccataagc aatatccaga caaagatttt ctgcttctat tttatgatta 7140 taatcaataa ccgaattgag aaactcagtc tcctggaaaa aaacctgctg cattatttcc 7200 tccgggaaat aacagaaata attatctttt gcaatctgtc gtaatatttc ggttgataaa 7260 atttatcgat cgacgccgga attttttcat gtgcgatgtg aatttcaccg gctatgtatt 7320 tattgagaag agcaacaaaa ccggtcatat cccccggttg atataaatga ccattaacat 7380 caggctgaat gatatcaaca ggcccggaga cacaatctgc actgatacaa gggatccccc 7440 acgacaaggc ttcaagtaga gtcattggga aaccttcaaa agatgacgtg agtaataatg 7500 cactcacttt tttaatatct tgctgaacta atttccaggg atgttgttgc caaccatacc 7560 agacaattcg atcatcaata tttaatcctc taccataagc ctggcatttt tcgaaatcgg 7620 agccatctcc caatacatga agtttccagt taccttgcac ttgtgataag ccatcaagca 7680 gatcttttac gcgcttttgg ccttcaaatt tcatgcgccc aacataaatg aatgttgccg 7740 tttcgccttc cccgggtgca ggaatgactg aatttttcgc ctcaacggga ttaaaaataa 7800 cgtttattgt cgattctggt acaccccggc taatcatttg ctgtttaata ccagagctga 7860 tggctaaatg atagtcggca caggtgatat attcggcatg ttttttatga tctaaagaaa 7920 aatgcggcca tgaaaataca ggtacatcaa tccccgattt tttacgagct ttggccgcat 7980 acaaacacga gatcacgtca atacaaataa caacatctgg ctgataatca tgaagccatt 8040 tgcttaaagc atgaatatgt ttcgcgcgac gcaaaaaacc taagcgaata ttggaaaatg 8100 aacacgagta cttaatacct tccagccatc ccttatccat tttgtcatta cgacaaaaga 8160 aaaaaatttc actttggata tgttgttgcc tgaaggtagt aataacatca cgaatgactg 8220 tttccatgcc gccaaatcca gaaacagctt cgccaataaa ggctattttc ataatttcat 8280 tccagctaaa tctttaagcc aaataattta acaagtaaat acttataata ataagaaatg 8340 gctttacaat attttccttc tagccaaaaa actttagact ttaacctaat ctcacttgat 8400 gatggagcta gatttctttt atggttcttc caaggagaat ttgaaaaata atgatcaaaa 8460 ttttgtgctc taaatatttt gtaccatggt ttattctggg taacataatg cattataatt 8520 gtgttgggca agtttttttg ttcttcatca catcgtactg acaatgttgt cttattattg 8580 tacttcttat caaggtaatg cactcgtcca ttaagtaaaa tattgagcac atcctgatct 8640 gcatacctat atacttttcc actgttgatc atttctaacg ctttttgtgt tatattattt 8700 tttttccatt cgctggtatt aataaacata accccggcat taaaataatt aataaactca 8760 atgccatagt ctaatttttt tacacgttct tgcatttctg gcgaatctgg aattacacat 8820 gcaatatcag catttaaatt ataatcaacc agttcatcta aaggaccatt acatatgaca 8880 tcacagtcaa gataaagtat cttatttatt ttatcatcaa taacttctgg gattaaaaaa 8940 cgtaaacatg ttgataaagg aataccaaga actaatgtat ccggattaat gtcaaattta 9000 tcagttatat aatatacaga tattgatgta ttaggacctt ctagttcgta aaaagctgaa 9060 cactcctttt cttctatgcc tgatataaga aggtgaaaat gaaggttaat atgtctattg 9120 ttagatataa ttgaatataa tgcaacaccc gctggcatta tgaattcacg gtcaaagcat 9180 agtgcaatat gtaaattttt aacatacgac acttcgtttt ggtataaatt tttcttctta 9240 gcaacgaagt ttctatattt caacaatttt agaatccctt tttgtaataa aatactattt 9300 acaagttttt tcttattgtt cttgcttcta tttttcctgc tttaatcctt gcctttttaa 9360 gtaaatcaat ctcaagtcta taaatatcgc gtaaaggcat cccaaaataa accttcataa 9420 atcgccagat atctctctgc gtcagaccaa tattcattga tgagaaatat aaaccaatca 9480 aatctttatc ccgccaacga cgtggtactt ttgcacgtat ctgtgcccgg tgcagatcga 9540 taaccgaaat ttttaattca tcttcccggc cagtaaatgg caaatggagt aaaaagtggc 9600 agatataaca atcacggtga ttaatccctg ctgcatgcat tttgcgcacc atggttgcca 9660 cacgcgcgat cagcatacgc ttaatatgta catcaggcgg gttgaccgcc caatctgcac 9720 aataatcttc aaggctaatt gtgggagtga gatcttcggt aataataaat gatgtgcgag 9780 ttaatggatt taaccctttt tcaccaaatc ctattccgtg catcgtatca acaccgacat 9840 catgcagtcg atgaatagcg tgccactctc tgtctgcacc taaaacgggc atccgcaatg 9900 agagcagatt ttttataatc tcctttaggg tcgtcccttt gtgccatttg aggaaataac 9960 ttttgccggc cagttcaaag cgtaatgtgc gacgcgtctc cagttcacgg aagacctcgc 10020 cattcagttt tttaacttct gcaaaggcat ctttaccacg ccagagtgtg gcaagtggct 10080 cttctaattc aaccatctaa accacctgta atgatatctg ccgctttctc cggcaggctg 10140 tataaatcct gagtatcggc gtaataccga gcattctccg cccaggccat gcgcaatgga 10200 gattgagtta acgctttacg taaaacgtca tttaattgtt cctgggagaa aggttcagcg 10260 atgaccgttc cacaattagc atctgtgata tagtgtgcgt atccgcatac cgcagtcgtc 10320 aacacaggta atcccgcggc aattgcctca aggagaacaa tacctgcagc ctcctgataa 10380 gcgggatgca ttaataaatc agcggctgcc attaattcag acacatcatt ccgcccggaa 10440 aagaaatgca ctttactacg cacaccgagt ttttctgcca gcacttcaaa tttacgcggt 10500 ttatcctggc caacaacaaa caacaacgta ttatggcgta acgattctgg taacgatgcc 10560 aaagcttcaa ttgagcgatc cacaccttta cgaccaaaat ctgaaccaac ctgcagcaat 10620 aagttttgtt gttcagtgat gccatttttc tggcgataaa tttcacgact gtttgggatt 10680 tgcgcgttgt attttctgtc aggatagata ccagggggaa gaatttgaaa acgttctggt 10740 tcagtttggt aatgcttctg aaaatcggcg atttgcttat cggtcaacat cataagtttc 10800 gtcgatttac catgttcgaa agtcgctcgc tcgaatgcag cataatggcg atagcgcgat 10860 gttaaacgat agaaaaatcc cttttcttgc gccactttct cggcataaca gacatcggcg 10920 gcaaaataaa catccagccc aggcatctta ttaaagccaa caacgcgatc agcgggatgt 10980 gccttcagat ggttttgaac ccaggcataa tattctgcat tacgtccatg gttagtatgg 11040 gatttaaccg gtacgcgaat aagctcaaat gcttccgggc aatcgccttc ccacgactgt 11100 gtatataccc gaacatggtg gccccgtgcg gcaactgttg aggcaatacg cataaagtca 11160 cgctgtagcc caccaaatgg aaaatattta tataagcaaa atgccacgat cataattgcg 11220 cattcctgtc agctgaaggt gcatcttctg gcaacagctt ttccgtagcg gcaatgacat 11280 cttccgctgg aataacagaa agatattttt tgttgcggtc aagttcgtgc cgggtaggca 11340 ttttttgata attccccgcc cagaactgaa taatattctc ggtccatgga cgccagaata 11400 catgatcagt ggccccaaac aggctaataa ctggcgtctt cacagccgct gcaatatgcc 11460 ccggcgcaga atccacacca ataaagagca ctgcatgatc aattaatgcg cccagttcag 11520 gaaaacgtgt tttaccggca aggccggtaa taggttttgt ttggcagcct cgtgcaattt 11580 catctacgca agcgagatca tctgccgaag ggccacaagt cagcacaacc tgataaccac 11640 gatgttgcaa cgcatcgata accatagaaa atttatcgtt gtcccagcac ttaaatatct 11700 gtctggctgt cggctggatg acgacataat gatctttcac gcccagtgca tctaattcct 11760 ggcgcatttt cttccagcaa tcctcggcgt aactcatggt tgtttcagta taaaaatcgg 11820 taatacctaa tggctcaagg accgacaaat tacgctcaac aatatgtgta ccgtgtatag 11880 gcgctaagtg tgtaaagctt tttttccaaa tgccatgctg ccgatgacca taaagctgcg 11940 atattttcat acgagcaggt aaacaacgta ccagcagggc caccatccac tgatccgtaa 12000 gattaatgac caggtcgtaa ttattcgcac gcagagtttt tatcagtgaa agtgcatttt 12060 taattttatc gaatgttccc gtacctttat tgcttatacc atagagtgca ttaatttctg 12120 ggttttcaga taaaatcgga attgtatcct ggtaaagcag catatcgatt tttgcgtcgg 12180 gataattctg cttgagtgta ctgattacag gagtagttaa taacatatct ccgtgatatc 12240 gcatctttat gaccaggatt tttcgaaatg gcttttccac tagcgactct tttgtgtgat 12300 tgtctggtta agttaagcag aaaaaagcac gctaccgccc caggctcaac agctacccga 12360 atactgataa cgcacttact ttgacgcgct agtgtatcat ttctttcgca gcaatccgac 12420 ccgaatgatt tttatacaca aaatatgttt taattataaa aatcatagag ataaaatttt 12480 gcatactcga gaatccagat attgtcgatg taaagctgca atcctggctg aaattcaatg 12540 aatcgcataa aaatacaaaa aaaatgaaga tctagcggca gatcagctca aacagaggct 12600 aattaagtca aaaaaaggaa aagtaatggc aaacccggtg ctaaatacat agaatcccca 12660 gcacatccat aagtcagcta tttattatgc ttgaattgct ttacaccgcc cttctctacc 12720 ttattcagcc gctgatctgg atacggctct gggtgcgcgg acgtaaggct ccggcctatc 12780 gaaaacgctg gggtgaacgt tacggttttt accgccatcc gctaaaacca ggcggcatta 12840 tgctgcactc cgtctccgtc ggtgaaactc tggcggcgat cccattggtg cgcgcgctgc 12900 gtcatcgtta tcctgattta ccgattaccg ttacaaccat gacaccaacc ggttcggagc 12960 gcgtacaatc ggctttcggg aaggatgttc agcacgttta tctgccatat gacctgcccg 13020 atgcacttaa tcgtttcctg aataaagtcg accctaaact ggtgttgatt atggaaaccg 13080 aactatggcc taacctgatt gcggcgctac ataaacgtaa aattccgctg gtgatcgcta 13140 acgcgcgact ctctgcccgc tcggccgcag gttatgccaa actgggtaaa ttcgtccgtc 13200 gcttgctgcg tcgtattacg ctgattgccg cccaaaatga agaagatggt gcacgttttg 13260 tggcgctgag cgcaaaaaat aatcaggtga ccgttaccgg tagcctgaaa ttcgatattt 13320 ctgtaacgcc gcaactggct gctaaagcag tgacgctgcg ccgccagtgg gcaccacacc 13380 gcccggtatg gattgccacc agcactcacg aaggtgaaga gagcgtggtc attgccgcac 13440 atcaggcatt attacagcaa ttcccgaatt tattgctcat cctggtaccc cgtcatccgg 13500 aacgcttccc ggatgcgatt aaccttgtcc gccaggctgg actaagctat atcacacgct 13560 cttcagggga agtcccctcc accagcacgc aggttgtggt tggcgatacg atgggcgagt 13620 tgatgttact gtacggcatt gccgatctcg cttttgttgg cggttcactg gttgaacgtg 13680 gtgggcataa tccgctggaa gctgccgcac acgctattcc ggtattgatg gggccgcata 13740 cttttaactt taaagacatt tgcgcgcggc tggagcaggc aagcgggctg attaccgtta 13800 ccgatgccac tacgcttgta aaagaggttt cctctttact caccgacgcc gattaccgta 13860 gtttctatgg ccgtcatgcc gttgaagtac tgtatcaaaa ccagggcgcg ctacagcgtc 13920 tgcttcaact gctggaacct tacctgccac cg 13952 // |
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