EBI Dbfetch

ID   AF016248; SV 1; linear; mRNA; STD; MAM; 1679 BP.
XX
AC   AF016248;
XX
DT   06-APR-1998 (Rel. 55, Created)
DT   15-APR-2005 (Rel. 83, Last updated, Version 4)
XX
DE   Canis familiaris cytochrome P450 2C41 mRNA, complete cds.
XX
KW   .
XX
OS   Canis lupus familiaris (dog)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
XX
RN   [1]
RP   1-1679
RX   PUBMED; 9492393.
RA   Blaisdell J., Goldstein J.A., Bai S.A.;
RT   "Isolation of a new canine cytochrome P450 CDNA from the cytochrome P450 2C
RT   subfamily (CYP2C41) and evidence for polymorphic differences in its
RT   expression";
RL   Drug Metab. Dispos. 26(3):278-283(1998).
XX
RN   [2]
RP   1-1679
RA   Bai S.A., Blaisdell J., Goldstein J.A.;
RT   ;
RL   Submitted (25-JUL-1997) to the EMBL/GenBank/DDBJ databases.
RL   APR, College of Veterinary Medicine, NCSU, 4700 Hillsborough Street,
RL   Raleigh, NC 27606, USA
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1679
FT                   /organism="Canis lupus familiaris"
FT                   /mol_type="mRNA"
FT                   /tissue_type="liver"
FT                   /db_xref="taxon:9615"
FT   CDS             2..1471
FT                   /codon_start=1
FT                   /product="cytochrome P450 2C41"
FT                   /note="oxidative enzyme; involved in the oxidation of
FT                   xenobiotics as well as endogenous substrates"
FT                   /db_xref="GOA:O62671"
FT                   /db_xref="HSSP:1OG2"
FT                   /db_xref="InterPro:IPR002401"
FT                   /db_xref="UniProtKB/Swiss-Prot:O62671"
FT                   /protein_id="AAC08738.1"
FT                   /translation="MDPVVVLVLCLSCCLLLSLWKQSSRKGKLPPGPTPLPFIGNILQL
FT                   DKDINKSLSNLSKAYGPVFTLYFGMKPTVVLHGYDAVKETLIDLGEEFSARGRFPIAEK
FT                   VSGGHGIIFTSGNRWKEMRRFALTTLRNLGMGKSDLESRVQEEACYLVEELRKTNALPC
FT                   DPTFVLGCASCNVICSIIFQNRFDYTDQTLIGFLEKLNENFRILSSPWIQAYNSFPALL
FT                   HYLPGSHNTIFKNFAFIKSYILEKIKEHQESFDVNNPRDFIDYFLIKMEQEKHNQPLEF
FT                   TFENLKTIATDLFGAGTETTSTTLRYGLLLLLKHPEVTVKVQEEIDRVIGRHQSPHMQD
FT                   RSRMPYTNAVLHEIQRYIDLVPNSLPHAVTCDVKFRNYVIPKGTTILISLSSVLSDEKE
FT                   FPRPEIFDPAHFLDDSGNFKKSDYFMAFSAGKRICVGEGLARMELFLFLTTILQKFTLK
FT                   PLVDPKDIDTTPLASGFGHVPPTYQLCFIPV"
XX
SQ   Sequence 1679 BP; 479 A; 408 C; 339 G; 452 T; 1 other;
     catggatcca gttgtggttc tggtgctttg tctctcctgt tgccttctcc tttcactctg        60
     gaaacagagc tcgaggaagg ggaagctccc acctggcccc acacctctcc cttttattgg       120
     aaatatccta cagttagata aggacatcaa caaatcctta agtaatctct caaaagccta       180
     tggccctgta ttcactctgt attttggcat gaaacccact gttgtactgc atgggtatga       240
     cgcagtgaag gaaaccctga ttgatctggg agaagagttt tctgcaagag gacgtttccc       300
     aatagccgaa aaagttagtg gaggacacgg aatcattttc accagtggaa acagatggaa       360
     ggagatgcga cgctttgccc tcacgaccct gcgaaatttg gggatgggga agagtgacct       420
     tgagagccga gttcaagagg aagcctgcta ccttgtagaa gagttgagaa aaaccaatgc       480
     cttaccatgt gatcccactt ttgtcttggg ctgtgcttcc tgcaatgtga tctgctccat       540
     tattttccag aatcgttttg actatacaga tcagacttta attggtttct tggaaaaact       600
     taatgaaaac ttcaggattt tgagctcccc atggatccag gcctacaata gtttccctgc       660
     tctccttcat tatctcccag gaagccataa cacaatattt aaaaattttg ctttcataaa       720
     aagttacatt ttggagaaaa taaaagaaca ccaagaatcc ttcgatgtta acaatcctcg       780
     ggatttcatt gattatttcc tgataaaaat ggaacaggaa aagcacaacc agccattgga       840
     atttactttc gaaaacttga aaactattgc cactgatttg tttggagctg ggacagagac       900
     aacaagcaca accctacgat atggtctcct gctcctgctg aaacatccag aagtcacagt       960
     gaaagtccag gaagagattg accgtgtaat tggcagacac cagagccctc acatgcagga      1020
     caggagtcgc atgccctaca cgaatgcggt actgcatgag attcagagat acattgacct      1080
     tgtcccaaac agcctgcctc atgcagtgac ctgtgacgtt aaatttagaa actatgtcat      1140
     ccccaagggc acaactatat taatatcact gtcttctgtg ctatctgatg aaaaagaatt      1200
     ccccagacca gagatatttg accctgccca cttcctggat gatagcggca acttcaagaa      1260
     gagtgactac ttcatggctt tctcagcagg aaaacgaatt tgtgtgggag aaggactggc      1320
     ccgcatggag ctgtttttat tcctgaccac cattttacaa aaatttaccc tgaaacctct      1380
     ggtcgatcca aaggacattg ataccacccc acttgccagt gggtttggcc atgtcccacc      1440
     cacctaccag ctctgcttca ttcccgtgtg aggaaaggca gaccacctgc ctgctgttgt      1500
     gctattgtct gtagatcctc ttcctctggg gtatcattca tctccctctc actactgggg      1560
     wtgctttccc cgaccttatc tcatatttcc ccattccttc cattcccagt gaacatccaa      1620
     cctccattaa aggaaagtct ccagaatttc tttgcaaaaa aaaaaaaaaa aaaaaaaaa       1679
//