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EBI DbfetchID AF012424; SV 1; linear; mRNA; STD; MAM; 2014 BP. XX AC AF012424; XX DT 06-JAN-1999 (Rel. 58, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Felis catus cell-type fibroblast mutant beta-glucuronidase (GUSB) mRNA, DE GUSB-MPS VII mutant allele, complete cds. XX KW . XX OS Felis catus (domestic cat) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis. XX RN [1] RP 1-2014 RX DOI; 10.1006/geno.1999.5825 RX PUBMED; 10366443. RA Fyfe J.C., Kurzhals R.L., Lassaline M.E., Henthorn P.S., Alur P.R., RA Wang P., Wolfe J.H., Giger U., Haskins M.E., Patterson D.F., Sun H., RA Jain S., Yuhki N.; RT "Molecular basis of feline beta-glucuronidase deficiency: an animal model RT of mucopolysaccharidosis VII"; RL Genomics 58(2):121-128(1999). XX RN [2] RP 1-2014 RA Fyfe J.C., Kurzhals R.L., Henthorn P.S.; RT ; RL Submitted (03-JUL-1997) to the EMBL/GenBank/DDBJ databases. RL Microbiology, Michigan State University, 413 Giltner Hall, East Lansing, MI RL 48824, USA XX FH Key Location/Qualifiers FH FT source 1..2014 FT /organism="Felis catus" FT /mol_type="mRNA" FT /cell_type="fibroblast" FT /db_xref="taxon:9685" FT CDS 2..1957 FT /codon_start=1 FT /gene="GUSB" FT /product="mutant beta-glucuronidase" FT /EC_number="3.2.1.31" FT /db_xref="GOA:O97524" FT /db_xref="HSSP:1BHG" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/Swiss-Prot:O97524" FT /protein_id="AAD01499.1" FT /translation="MLRGPAAVWAALGPLLWACGLALRGGMLYPRESPSRERKELNGLW FT SFRADFSENRRQGFEQQWYRTPLRESGPTLDMPVPSSFNDVGQDRQLRSFVGWVWYERE FT ATLPQRWTQDLGTRVVLRIGSAHYYAIVWVNGVHVAEHEGGHLPFEADISKLVQSGPLA FT SCRITIAINNTLTPHTLPPGTILYQTDTSKYPKGYFVQNINFDFFNYAGLHRPVLLYTT FT PTTYIDDITISTSVNQDTGLVDYQIFVEGGEHFQLEVRLLDEEGKVVAQGTGGRGQLQV FT PNAHLWWPYLMHEHPAYLYSLEVRLTAQTAAGSVSDFYTLPVGIRTVAVTEHQFLINGK FT PFYFHGVNKHKDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQLCDRYG FT IVVIDESPGVGIVLVESYSNVSLQHHLEVMEELVRRDKNHPAVVMWSVANEPASFLKPA FT GYYFKTLIAHTKALDPSRPVTFVTNSNYEADLGAPYVDVICVNSYYSWYHDYGHMEVIQ FT LQLATQFENWYRTYQKPIIQSEYGADTIAGFHQDPPLMFSEEYQKGLLEQYHLVLDQKR FT KEYVVGELIWNFADFMTNQSPQRVMGNKKGIFTRQRQPKGAAFLLRERYWKLANETRYP FT WSAVKSQCLENSPFTL" XX SQ Sequence 2014 BP; 443 A; 570 C; 588 G; 413 T; 0 other; catgctccgg gggccggcgg cggtctgggc ggcgctcggc ccgctgcttt gggcctgcgg 60 gctggcgctg cggggcggga tgctctaccc ccgggagagc ccgtcgcggg agcgcaagga 120 gctgaacggc ctctggagct tccgcgccga cttctccgag aaccggcgcc agggcttcga 180 gcagcagtgg taccggaccc cgctgcgcga gtcgggcccc accctggaca tgccggttcc 240 ctccagcttc aatgacgtgg gccaggatag gcagctgcga agctttgtcg gctgggtgtg 300 gtacgagcgg gaggcgaccc tgccccagcg atggactcag gacctgggca ccagagtggt 360 gctgaggatt ggcagcgccc actactatgc cattgtgtgg gtgaatgggg tccacgtggc 420 agagcatgag gggggccatc tccccttcga ggctgacatc agcaagctgg tacagagtgg 480 gcccctggcc tcttgccgca ttaccattgc catcaacaac acgctcaccc cccacactct 540 gccgccaggg accatcctct accagacgga tacctccaag taccccaagg gttactttgt 600 ccagaacata aactttgact tcttcaacta cgcggggctg catcggcccg tgctcctcta 660 taccacacct accacctaca tcgatgacat caccatcagc accagcgtga accaagacac 720 tgggctggtg gattaccaga tttttgttga aggcggtgaa cactttcaac tggaagtgcg 780 tcttctggat gaggaaggca aagtcgtggc ccaggggaca gggggtcggg gccagctgca 840 ggtgcccaat gcccacctct ggtggccata cctgatgcat gagcaccctg cctacctgta 900 ctcattggag gtgaggttga ccgcgcagac ggcagctggg tctgtgtctg acttctacac 960 tctccccgtg gggattcgca cggtggctgt cacagagcac cagttcctca tcaatgggaa 1020 acctttctat ttccacgggg tcaacaagca caaggatgca gatatccgag ggaagggctt 1080 tgactggcca ctgctggtga aggacttcaa tttgcttcgc tggctcgggg ccaacgcctt 1140 ccgcaccagt cactacccct acgcggagga ggtgatgcag ctctgtgacc gctatgggat 1200 cgtggtcatc gacgagagtc ccggtgtggg catcgtgctg gtcgagagct acagcaacgt 1260 gtctctgcag caccacctgg aggtgatgga ggagctggtg cgcagggaca agaatcaccc 1320 ggctgttgtg atgtggtctg tggccaatga gcccgcttcc ttcctgaaac ctgccggtta 1380 ctacttcaag acgctgattg ctcacaccaa agccttggat ccctcccggc ccgtgacctt 1440 tgtgaccaac tccaactatg aagcagacct gggggcgccg tatgtggacg tcatctgtgt 1500 gaatagttac tactcttggt atcatgacta tggtcacatg gaggtgattc agctgcagct 1560 ggcaacccag tttgagaact ggtataggac ctatcagaaa ccaataatcc agagcgagta 1620 cggagcagac accattgcag ggtttcacca ggacccacct ctgatgttca gcgaggaata 1680 ccagaaaggt ctgctggagc agtatcattt ggttctggat caaaaacgca aagaatacgt 1740 ggtcggagag ctcatctgga actttgccga ttttatgact aaccagtcac cgcagagagt 1800 aatggggaat aaaaagggga tcttcacgcg ccagagacaa ccaaaagggg cagcgttcct 1860 tttgcgagag agatactgga aacttgccaa tgaaaccagg tatccctggt cagctgtgaa 1920 gtcacagtgt ttggaaaaca gcccatttac tctttaaagc aagaactacc tctgctgaca 1980 agagcagata gcagcccctc ctccacaagt aagg 2014 // |
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