 |
|
EBI DbfetchID AF012423; SV 1; linear; mRNA; STD; MAM; 2153 BP. XX AC AF012423; XX DT 06-JAN-1999 (Rel. 58, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Felis catus beta-glucuronidase (GUSB) mRNA, complete cds. XX KW . XX OS Felis catus (domestic cat) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis. XX RN [1] RP 1-2153 RX DOI; 10.1006/geno.1999.5825 RX PUBMED; 10366443. RA Fyfe J.C., Kurzhals R.L., Lassaline M.E., Henthorn P.S., Alur P.R., RA Wang P., Wolfe J.H., Giger U., Haskins M.E., Patterson D.F., Sun H., RA Jain S., Yuhki N.; RT "Molecular basis of feline beta-glucuronidase deficiency: an animal model RT of mucopolysaccharidosis VII"; RL Genomics 58(2):121-128(1999). XX RN [2] RP 1-2153 RA Fyfe J.C., Kurzhals R.L., Henthorn P.S.; RT ; RL Submitted (03-JUL-1997) to the EMBL/GenBank/DDBJ databases. RL Microbiology, Michigan State University, 413 Giltner Hall, East Lansing, MI RL 48824, USA XX FH Key Location/Qualifiers FH FT source 1..2153 FT /organism="Felis catus" FT /mol_type="mRNA" FT /tissue_type="liver" FT /db_xref="taxon:9685" FT CDS 24..1979 FT /codon_start=1 FT /gene="GUSB" FT /product="beta-glucuronidase" FT /EC_number="3.2.1.31" FT /note="lysosomal hydrolase; lysosomal exooligosaccharidase FT in stepwise degradation of glucuronic acid-containing FT oligosaccharide sidechains of proteoglycans" FT /db_xref="GOA:O97524" FT /db_xref="HSSP:1BHG" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/Swiss-Prot:O97524" FT /protein_id="AAD01498.1" FT /translation="MLRGPAAVWAALGPLLWACGLALRGGMLYPRESPSRERKELNGLW FT SFRADFSENRRQGFEQQWYRTPLRESGPTLDMPVPSSFNDVGQDRQLRSFVGWVWYERE FT ATLPQRWTQDLGTRVVLRIGSAHYYAIVWVNGVHVAEHEGGHLPFEADISKLVQSGPLA FT SCRITIAINNTLTPHTLPPGTILYQTDTSKYPKGYFVQNINFDFFNYAGLHRPVLLYTT FT PTTYIDDITISTSVNQDTGLVDYQIFVEGGEHFQLEVRLLDEEGKVVAQGTGGRGQLQV FT PNAHLWWPYLMHEHPAYLYSLEVRLTAQTAAGSVSDFYTLPVGIRTVAVTEHQFLINGK FT PFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQLCDRYG FT IVVIDESPGVGIVLVESYSNVSLQHHLEVMEELVRRDKNHPAVVMWSVANEPASFLKPA FT GYYFKTLIAHTKALDPSRPVTFVTNSNYEADLGAPYVDVICVNSYYSWYHDYGHMEVIQ FT LQLATQFENWYRTYQKPIIQSEYGADTIAGFHQDPPLMFSEEYQKGLLEQYHLVLDQKR FT KEYVVGELIWNFADFMTNQSPQRVMGNKKGIFTRQRQPKGAAFLLRERYWKLANETRYP FT WSAVKSQCLENSPFTL" XX SQ Sequence 2153 BP; 478 A; 599 C; 629 G; 447 T; 0 other; ctgtgagctg ccacgagcga agcatgctcc gggggccggc ggcggtctgg gcggcgctcg 60 gcccgctgct ttgggcctgc gggctggcgc tgcggggcgg gatgctctac ccccgggaga 120 gcccgtcgcg ggagcgcaag gagctgaacg gcctctggag cttccgcgcc gacttctccg 180 agaaccggcg ccagggcttc gagcagcagt ggtaccggac cccgctgcgc gagtcgggcc 240 ccaccctgga catgccggtt ccctccagct tcaatgacgt gggccaggat aggcagctgc 300 gaagctttgt cggctgggtg tggtacgagc gggaggcgac cctgccccag cgatggactc 360 aggacctggg caccagagtg gtgctgagga ttggcagcgc ccactactat gccattgtgt 420 gggtgaatgg ggtccacgtg gcagagcatg aggggggcca tctccccttc gaggctgaca 480 tcagcaagct ggtacagagt gggcccctgg cctcttgccg cattaccatt gccatcaaca 540 acacgctcac cccccacact ctgccgccag ggaccatcct ctaccagacg gatacctcca 600 agtaccccaa gggttacttt gtccagaaca taaactttga cttcttcaac tacgcggggc 660 tgcatcggcc cgtgctcctc tataccacac ctaccaccta catcgatgac atcaccatca 720 gcaccagcgt gaaccaagac actgggctgg tggattacca gatttttgtt gaaggcggtg 780 aacactttca actggaagtg cgtcttctgg atgaggaagg caaagtcgtg gcccagggga 840 cagggggtcg gggccagctg caggtgccca atgcccacct ctggtggcca tacctgatgc 900 atgagcaccc tgcctacctg tactcattgg aggtgaggtt gaccgcgcag acggcagctg 960 ggtctgtgtc tgacttctac actctccccg tggggattcg cacggtggct gtcacagagc 1020 accagttcct catcaatggg aaacctttct atttccacgg ggtcaacaag cacgaggatg 1080 cagatatccg agggaagggc tttgactggc cactgctggt gaaggacttc aatttgcttc 1140 gctggctcgg ggccaacgcc ttccgcacca gtcactaccc ctacgcggag gaggtgatgc 1200 agctctgtga ccgctatggg atcgtggtca tcgacgagag tcccggtgtg ggcatcgtgc 1260 tggtcgagag ctacagcaac gtgtctctgc agcaccacct ggaggtgatg gaggagctgg 1320 tgcgcaggga caagaatcac ccggctgttg tgatgtggtc tgtggccaat gagcccgctt 1380 ccttcctgaa acctgccggt tactacttca agacgctgat tgctcacacc aaagccttgg 1440 atccctcccg gcccgtgacc tttgtgacca actccaacta tgaagcagac ctgggggcgc 1500 cgtatgtgga cgtcatctgt gtgaatagtt actactcttg gtatcatgac tatggtcaca 1560 tggaggtgat tcagctgcag ctggcaaccc agtttgagaa ctggtatagg acctatcaga 1620 aaccaataat ccagagcgag tacggagcag acaccattgc agggtttcac caggacccac 1680 ctctgatgtt cagcgaggaa taccagaaag gtctgctgga gcagtatcat ttggttctgg 1740 atcaaaaacg caaagaatac gtggtcggag agctcatctg gaactttgcc gattttatga 1800 ctaaccagtc accgcagaga gtaatgggga ataaaaaggg gatcttcacg cgccagagac 1860 aaccaaaagg ggcagcgttc cttttgcgag agagatactg gaaacttgcc aatgaaacca 1920 ggtatccctg gtcagctgtg aagtcacagt gtttggaaaa cagcccattt actctttaaa 1980 gcaagaacta cctctgctga caagagcaga tagcagcccc tcctccacaa gtaaggggca 2040 acttccacag cagtcctgga ctatgcatgg tcgactggga agtttctggc ccggattttg 2100 tactaattta ccagaaggga atgtcagagg tgcaaataaa agctttcgta gtg 2153 // |
|