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EBI DbfetchID AF011922; SV 1; linear; genomic DNA; STD; PRO; 12949 BP. XX AC AF011922; XX DT 04-DEC-1997 (Rel. 53, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 5) XX DE Pseudomonas aeruginosa aru gene cluster, ArgR regulatory protein (argR), DE succinylornithine aminotransferase (aruC), arginine/ornithine DE succinyltransferase AI subunit (aruF), arginine/ornithine DE succinyltransferase AII subunit (aruG), succinylglutamate 5-semialdehyde DE dehydrogenase (aruD), succinylarginine dihydrolase (aruB), DE succinylglutamate desuccinylase (aruE) genes, complete cds; and alanine DE tRNA synthetase (alaS) gene, partial cds. XX KW . XX OS Pseudomonas aeruginosa OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; OC Pseudomonadaceae; Pseudomonas. XX RN [1] RP 1-12949 RX PUBMED; 9286980. RA Park S.M., Lu C.D., Abdelal A.T.; RT "Cloning and characterization of argR, a gene that participates in RT regulation of arginine biosynthesis and catabolism in Pseudomonas RT aeruginosa PAO1"; RL J. Bacteriol. 179(17):5300-5308(1997). XX RN [2] RP 1-12949 RX PUBMED; 9393691. RA Itoh Y.; RT "Cloning and characterization of the aru genes encoding enzymes of the RT catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa"; RL J. Bacteriol. 179(23):7280-7290(1997). XX RN [3] RP 1-12949 RA Itoh Y.; RT ; RL Submitted (30-JUN-1997) to the EMBL/GenBank/DDBJ databases. RL Applied Microbiology, National Food Research Institute, 2-1-2 Kannondai, RL Tsukuba 305, Japan XX FH Key Location/Qualifiers FH FT source 1..12949 FT /organism="Pseudomonas aeruginosa" FT /strain="PAO1" FT /mol_type="genomic DNA" FT /db_xref="taxon:287" FT CDS 1993..2982 FT /codon_start=1 FT /transl_table=11 FT /gene="argR" FT /product="ArgR regulatory protein" FT /note="AraC/XylS family; transcription activator, FT transcription repressor" FT /db_xref="GOA:O30507" FT /db_xref="InterPro:IPR018062" FT /db_xref="UniProtKB/TrEMBL:O30507" FT /protein_id="AAC46008.1" FT /translation="MTAQPQRIGFLLWPATRALTLSLAEEALRAARRLHPEALYEPLFL FT LAEAPAEEEGWRLPGTAWNGRLEQCSRLFLVADEAPAAVSPALGLALKQLARSGAAIGA FT LSAGIYPLAQLGLLDGYRAAVHWRWHDDFTERFPKVIATNHLFEWDRDRMTACGGMAVL FT DLLLALLSRDHGAELAGAVSEELVVERIREGNERQRIPLKNRLGSSHPKLTQAVLLMEA FT NIEEPLTTDEIAQHVCVSRRQLERIFKQYLNRVPSQYYLELRLNRARQMLMQTSKSIIQ FT IGLSCGFSSGPHFSSAYRNFFGVTPREDRNQRRGGSAFETTFTPVERG" FT CDS 3493..4713 FT /codon_start=1 FT /transl_table=11 FT /gene="aruC" FT /product="succinylornithine aminotransferase" FT /note="aminotransferase; arginine catabolic and possible FT anabolic gene" FT /db_xref="GOA:O30508" FT /db_xref="HSSP:1QJ3" FT /db_xref="InterPro:IPR017652" FT /db_xref="UniProtKB/Swiss-Prot:O30508" FT /protein_id="AAC46009.1" FT /translation="MSAPHAQVERADFDRYMVPNYAPAAFIPVRGEGSRVWDQSGRELI FT DFAGGIAVTSLGHAHPALVKALTEQAQRIWHVSNVFTNEPALRLARKLVDATFAERVFL FT ANSGAEANEAAFKLARRYANDVYGPQKYEIIAASNSFHGRTLFTVNVGGQPKYSDGFGP FT KFEGITHVPYNDLEALKAAISDKTCAVVLEPIQGEGGVLPAQQAYLEGARKLCDEHNAL FT LVFDEVQSGMGRVGELFAYMHYGVVPDILSSAKSLGGGFPIGAMLTTGEIAKHLSVGTH FT GTTYGGNPLASAVAEAALDVINTPEVLDGVKAKHERFKSRLQKIGQEYGIFDEIRGMGL FT LIGAALTDEWKGKARDVLNAAEKEAVMVLQASPDVVRFAPSLVIDDAEIDEGLERFERA FT VAKLVRG" FT CDS 4911..5927 FT /codon_start=1 FT /transl_table=11 FT /gene="aruF" FT /product="arginine/ornithine succinyltransferase AI FT subunit" FT /note="succinyltransferase; catabolic" FT /db_xref="GOA:P80357" FT /db_xref="InterPro:IPR017651" FT /db_xref="PDB:1YLE" FT /db_xref="UniProtKB/Swiss-Prot:P80357" FT /protein_id="AAC46010.1" FT /translation="MLVMRPAQAADLPQVQRLAADSPVGVTSLPDDAERLRDKILASEA FT SFAAEVSYNGEESYFFVLEDSASGELVGCSAIVASAGFSEPFYSFRNETFVHASRSLSI FT HNKIHVLSLCHDLTGNSLLTSFYVQRDLVQSVYAELNSRGRLLFMASHPERFADAVVVE FT IVGYSDEQGESPFWNAVGRNFFDLNYIEAEKLSGLKSRTFLAELMPHYPIYVPLLPDAA FT QESMGQVHPRAQITFDILMREGFETDNYIDIFDGGPTLHARTSGIRSIAQSRVVPVKIG FT EAPKSGRPYLVTNGQLQDFRAVVLDLDWAPGKPVALSVEAAEALGVGEGASVRLVAV" FT CDS 5939..6961 FT /codon_start=1 FT /transl_table=11 FT /gene="aruG" FT /product="arginine/ornithine succinyltransferase AII FT subunit" FT /note="succinyltransferase; catabolic" FT /db_xref="GOA:P80358" FT /db_xref="InterPro:IPR017650" FT /db_xref="UniProtKB/Swiss-Prot:P80358" FT /protein_id="AAC46011.1" FT /translation="MIVRPVTSADLPALIELARSTGTGLTTLPANEQRLQHRVSWAEKA FT FRGEAERGDADYLFVLEDDAGKVVGISAIAGAVGLREPWYNYRVGLTVSASQELNIHRE FT IPTLFLANDLTGNSELCSLFLHADHRSGLNGKLLSRARFLFIAEFRHLFGDKLIAEMRG FT MSDEEGRSPFWESLGRHFFKMEFSQADYLTGVGNKAFIAELMPKFPLYTCFLSEEARGV FT IGRVHPNTEPALAMLKAEGFSYQGYVDIFDAGPAIEAETDKIRAIAESQNLVLAVGTPG FT DDAEPYLIHNRKREDCRITAAPARAAAGTLVVDPLTAKRLRLSAGASVRAVPLSAQKRG FT " FT CDS 7004..8470 FT /codon_start=1 FT /transl_table=11 FT /gene="aruD" FT /product="succinylglutamate 5-semialdehyde dehydrogenase" FT /note="aldehyde dehydrogenase; catabolic" FT /db_xref="GOA:O50174" FT /db_xref="InterPro:IPR017649" FT /db_xref="UniProtKB/Swiss-Prot:O50174" FT /protein_id="AAC46012.1" FT /translation="MMSTHYIAGQWLAGQGETLESLDPVGQGVVWSGRGADATQVDAAV FT CAAREAFPAWARRPLEQRIELLERFAATLKSRADELARVIGEETGKPLWESATEVTSMV FT NKVAISVQAFRERTGEKSGPLADATAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLA FT GNCVVFKPSELTPKVAELTLKAWIQAGLPAGVLNLVQGGRETGVALAAHRGLDGLFFTG FT SSRTGNLLHSQFGGQPQKILALEMGGNNPLVVEEVADLDAAVYTIIQSAFISAGQRCTC FT ARRLLVPQGAWGDALLARLVAVSATLRVGRFDEQPAPFMGAVISLSAAEHLLKAQEHLI FT GKGAQPLLAMTQPIDGAALLTPGILDVSAVAERPDEEFFGPLLQVIRYSDFAAAIREAN FT ATQYGLAAGLLSDSRERFEQFLVESRAGIVNWNKQLTGAASSAPFGGIGASGNHRPSAY FT YAADYCAYPVASLESPSVSLPATLTPGISL" FT CDS 8467..9813 FT /codon_start=1 FT /transl_table=11 FT /gene="aruB" FT /product="succinylarginine dihydrolase" FT /note="catabolic" FT /db_xref="GOA:O50175" FT /db_xref="InterPro:IPR007079" FT /db_xref="UniProtKB/Swiss-Prot:O50175" FT /protein_id="AAC46013.1" FT /translation="MNAHEVNFDGLVGPTHNYGGLSYGNVASQSNSQAVSNPKEAAKQG FT LAKMKALMEMGFKQGVLAPQARPDTAALRSLGFSGSDEEVIRRAAKEAMPLLAACSSAS FT SMWTANAATVSPSADTADGRVHFTAANLNCKFHRSIEHPTTSRVLAAMFNDERHFAHHA FT ALPAVSQFGDEGAANHTRFCKDYGDAGVEFFVFGRSAFDSRFPAPQRYPARQTLEACQA FT VARLHGLSEAGVVYAQQNPAVIDQGVFHNDVISVGNGEVLFHHEDAFLDTEKVLAELHD FT KLGRRGGRFRAICVPRDQVAVEDAVKSYLFNSQLLSKADGSMLLVVPEECRNNPRVWNY FT LDQLTGDDGPIREVKVFDLKQSMQNGGGPACLRLRVALQERELAAVNPGVIMSAGLYDT FT LVAWVDRHYRDRLSETDLADPQLLLECRTALDELTQILKLGSVYSFQLD" FT CDS 9827..10117 FT /codon_start=1 FT /transl_table=11 FT /product="hypothetical 10.6 kD protein" FT /note="similiar to yoiF and nusB of Escherichia coli" FT /db_xref="UniProtKB/TrEMBL:O50176" FT /protein_id="AAC46015.1" FT /translation="MSDSLQLILEDTDGTQLETSCTRFAVVWQGKEVWVQQAGNGQLLI FT GVDVEDGDTEYTNLLLRPMATNLVSLQLEMEPIEEGDDHEHGPDCGCDHTH" FT CDS 10131..11129 FT /codon_start=1 FT /transl_table=11 FT /gene="aruE" FT /product="succinylglutamate desuccinylase" FT /note="catabolic" FT /db_xref="GOA:O50177" FT /db_xref="InterPro:IPR016681" FT /db_xref="UniProtKB/Swiss-Prot:O50177" FT /protein_id="AAC46014.1" FT /translation="MLALGKLLDLTLAGREPTEKIQLTADGTRLHWLAEGALEVTPIGA FT RDNGVDLLLSAGIHGNETAPIELLERLIRKVAAGTLKPAARVLFLFGNPEAIRRGERYV FT EQDMNRLFNGRHEEGSGNEAFRAAELERLAQVFFSKTERVHLHYDLHTAIRGSKIEQFA FT LYPWAEGRQHSRSELARLRDAGIEAVLLQNKPGITFSAYTYGQLGAEAFTLELGKARPF FT GENQEVNLERLERSLELLIDGSEEQPDGSRLDGLKLFSVSREVIKHSDHFRLHLDDDVA FT NFTELSPGYLLAEDIGGTRWVVDEVGARIIFPNPRVKNGLRAGILVVPAKL" FT CDS 11274..12278 FT /codon_start=1 FT /transl_table=11 FT /gene="gly1" FT /product="L-allo-threonine aldolase" FT /note="similar to gly1 of Saccharomyces cereviseae" FT /db_xref="GOA:O50178" FT /db_xref="HSSP:1JG8" FT /db_xref="InterPro:IPR015422" FT /db_xref="UniProtKB/TrEMBL:O50178" FT /inference="non-experimental evidence, no additional FT details recorded" FT /protein_id="AAC46016.1" FT /translation="MPVIDLRSDTVTQPTAGMREAMAAAELGDDVYGEDPTVNRLEAEL FT AARLGFAAALFVPTGTMSNLLGLMAHCERGDEYIVGQQAHTYKYEGGGAAVLGSIQPQP FT IDGEADGSLHLDKVAAAIKADDFHFARTRLLALENTMQGKVLPLDYLAAARAFTRARGL FT ALHLDGARLYNAAVKLGVDASEITRHFDSVSVCLSKGLGAPVGSVLCGSVELIGKARRW FT RKMVGGGMRQAGLLAAAGLYALDHQVARLADDHANAARLGDGLRELGYAVEPVQTNMVY FT VDVGERAVALRDFLAERGVRISAAARLRLVTHLDVSAESIGQVLDAFAAFRRS" FT CDS 12400..>12949 FT /codon_start=1 FT /transl_table=11 FT /gene="alaS" FT /product="alanine tRNA synthetase" FT /db_xref="GOA:Q9I553" FT /db_xref="InterPro:IPR012947" FT /db_xref="UniProtKB/Swiss-Prot:Q9I553" FT /inference="non-experimental evidence, no additional FT details recorded" FT /protein_id="AAC46017.1" FT /translation="MKSAEIREAFLRFFEEKGHTRVASSSLIPANDPTLLFTNAGMNQF FT KDCFLGLEKRAYTRATTSQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRD FT AIHYAWEFLTGEKWLNLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGDNKGAPY FT ASDNFWAMGDTGPCGPCTEI" XX SQ Sequence 12949 BP; 2217 A; 4452 C; 4237 G; 2043 T; 0 other; aagcttgccg agcgccgctg gctggcctac ctggcgccgc gcaaatcctg atccggagga 60 ccgcatggag cgtatcgacc acctgctgcc gtggagcacc ctgggaagcg agaagcgcct 120 gagcgtgttc cgcttcggct gcggcgcgcg caaggtctac atccagtcca gcctgcacgc 180 cgacgagttg ccgggcatgc gcaccgcctg ggagctgaag cagcggttgc gcctgctgga 240 ggcggaaggc cgcctgcgcg gcaccgtcga gctggtgccg gtggccaatc cggtcggtct 300 cgggcagatg atccaggcgc tgcaccaggg gcgcttcgaa atgagcagcg ggcgcaactt 360 caatcgcgat ttccccgacc tgctggacgc ggtgatcgac agcgtcggcg agcgtctcgg 420 cagcgatccg gcggccaatg tcgcgctggt ccgccaggcc ctgcgcgcgg cgctggacgc 480 cctgccgccg gcgacctcgg aactggaggg catgcagcgc ctgctgtatc gccacgcctg 540 cgacgccgac ctggtgctcg acctgcattg cgacttcgag gccgccatcc atctctatac 600 cctgccgcag caatggcccg ccttcgcctc cctggccgca cgcctgggcg ccgctgtcgg 660 gctgctcgcc gaggagtccg gcggcggttc cttcgacgag gcctgctcgg tgccgtggct 720 gcgcctgtcg cgcctgtatc cgcgcgccga gctgccgctg gcctgcctgg cgaccaccgt 780 cgaactcggc ggccaggccg acaccaccgt gcagcaggcc gaggccaacg ccgcggcgat 840 cctggccttc ctcgccgagc agggcttcgt cgagggcgaa tggccggcgg cgcccgaagc 900 ctgctgcgaa ggcttgccct tcgagggcac cgaatacgtc cacgccccgc ataccggcgt 960 ggtgagtttc ctgcgccggc cgggcgaatg ggtggaggcg ggcgaaccgc tgttccaggt 1020 catcgatccc ctggccgacc gtgccagcac cgtgtgcgcc ggggtttccg gcgtgctttt 1080 cgccatcgaa cggatgcgct acgcgcagcc gggactctgg ctggccaagg tggccggtcg 1140 tcaaccgatc cgtcagggac gcttgctcag cgactgatta gccgagaaca cacacatgta 1200 caaactggaa gtccaagacc tgcacaagcg ctacggtagc cacgaggtgc tcaagggcgt 1260 ctcgctggcg gcgaaagcgg gcgacgtgat cagcatcatc ggctcgagcg gttccggcaa 1320 gagcaccttt ctgcgctgca taaacctgct ggaacagccg cacgccggca agatcctgct 1380 caacggcgag gagctgaagc tggtgcccgg ccgcgacggc gcgctgaagg ccgccgactc 1440 ccgccagttg cagcgcatgc gctcgcgcct gtcgatggtg ttccagcatt tcaacctgtg 1500 gtcgcacatg agcgccctgg agaacgtcat cgaggcgccc gtgcatgtgc tcggcgtgtc 1560 gaagaaggaa gccatcgaga aggccgagca ctacctggcc aaggtcggcg tggcgcaccg 1620 caaggacgcc tacccggcgc acatgagcgg cggcgagcag cagcgcgtgg cgatcgcccg 1680 ggcgctggcg gtggagccgg aagtgatgct gttcgacgag ccgacctcgg cgctcgaccc 1740 cgaactggtg ggcgaagtgc tgaaggtcat gcaggacctg gcccaggaag gccgcaccat 1800 ggtggtggtg acccacgaga tgggtttcgc ccgcgaggtg tcgaaccagt tggtgttcct 1860 gcacaagggc ctggtcgagg aacacggctg cccgaaggaa gtcctcgcca acccgcagtc 1920 ggaccgcctc aagcagttcc tctccggcag cctcaagtaa cattcatcgc agaggccggc 1980 taagctgctc ccatgactgc ccaaccccaa cgcatcggtt tcctcctctg gcccgccacc 2040 cgcgcgctga cgctatcgct tgccgaggaa gccctgcggg cggcccggcg gttgcacccc 2100 gaggcgctct acgagccgct gttcctgctc gccgaagcgc cggccgaaga ggagggctgg 2160 cgcctgccgg gaacggcctg gaacggcagg ctggagcaat gctcgcggct gttcctggtc 2220 gccgacgagg cgccggcggc ggtgtcgcca gcgctgggcc tggcgctcaa gcaactggcg 2280 cgttcgggag cagcgatcgg cgcgctgtcc gccggcatct acccgctggc ccagctcggc 2340 ctgctcgacg gctatcgcgc cgcggtgcac tggcgttggc acgacgactt caccgagcgc 2400 ttccccaagg tcatcgccac caatcacctg ttcgagtggg atcgcgaccg catgaccgcc 2460 tgcggcggca tggcggtact cgacctgctg ctggcgctgc tgtcccgcga ccatggcgct 2520 gaactggccg gcgcggtctc ggaagagctg gtggtggagc gcattcgcga aggcaacgag 2580 cgccagcgca tcccgctgaa gaatcgcctc ggctccagcc atccgaagct gacccaggcg 2640 gtactgctga tggaagccaa tatcgaggag ccactgacca ccgacgagat cgcccagcat 2700 gtgtgtgttt cgcggcgcca gttggaacgg atcttcaagc aatacctgaa ccgcgtaccc 2760 agccagtact acctggagct gcgcctgaac cgcgcgcggc agatgctgat gcagaccagc 2820 aagtcgatca tccagatcgg cctgtcctgc ggtttctctt ctgggccgca tttctccagc 2880 gcctaccgca acttcttcgg cgtcactccg cgcgaggacc gcaaccagcg gcgcggcggc 2940 agcgccttcg agacgacctt cactcccgtc gaacgcggct gatcgccaac ggcgcggcgg 3000 tttcagccgg gctttgcgac gccccgggag gcggatcgcc tcgggaagtc gccgagttcg 3060 cgacgggccg tcggaatgat cgcctccagc agttccagcg gaacgtcgct ggcgaacagg 3120 ttgaccacga aacgccggcc gacgtcgtcg cgaaagacct cgaacagcgg ctgttcgccg 3180 cgccagcact ccaggccgag gccgtcgcgc ggattgacgt cggaggcgaa gacgagacgg 3240 tagtcgattc cctcgatggg catggcttgt ttccctgctg ttcccgcccg cggggcggcg 3300 tagaagaagt atgcacccga gtgcatcgcg cgtttacact gcgccttccc gatgctttct 3360 gtcgcatttc cgaaagccgc ggaaattccc gggttggcgc tataacaagt tgtcgcatgg 3420 cggcaatgcc ggcccggtcc caatccctac aatcctttca tcgatagccg ccttcaggca 3480 ggagaaacac cgatgtccgc tccccatgcg caggtagaac gtgccgattt cgaccggtat 3540 atggtcccca actacgcccc cgccgccttc attccggtgc gaggcgaggg atcgcgcgtc 3600 tgggaccaga gcggccgcga actgatcgat ttcgccggcg gcatcgccgt gacctccctg 3660 ggccacgcgc atccggcgct ggtcaaggcg ctcaccgagc aggcccagcg catctggcac 3720 gtttccaacg tcttcactaa cgagccggcc ctgcgcctgg cgcgcaagct ggtggacgcc 3780 accttcgccg agcgggtgtt cctcgccaat tccggcgccg aagccaacga ggcggccttc 3840 aagctggctc gccgctacgc caacgatgtc tacggcccgc agaagtacga gatcatcgcc 3900 gccagcaaca gcttccacgg gcgcaccctg ttcaccgtca acgtcggcgg ccagccgaag 3960 tattccgatg gcttcgggcc caagttcgag ggtatcaccc acgttcccta caacgacctg 4020 gaagcgctga aggcggcgat ctccgacaag acctgcgccg tggtgctgga accgatccag 4080 ggcgagggcg gcgtgctgcc ggcgcagcag gcctacctgg aaggggcgcg caagctgtgc 4140 gacgagcaca acgcgctgct ggtcttcgac gaggtccaga gcggcatggg ccgggtcggc 4200 gagctgttcg cctacatgca ctacggcgtg gtcccggaca tcctctccag cgccaagagc 4260 ctgggcggcg gcttccctat cggtgcgatg ctgaccaccg gcgagatcgc caagcacctg 4320 tcggtcggca cccacggcac cacctacggc ggcaacccgc tggcgtcggc ggtggccgag 4380 gcggcgctgg acgtgatcaa taccccggaa gtgctggatg gcgtgaaggc caagcatgag 4440 cgcttcaagt cccgcctgca gaagatcggc caggagtacg gcatcttcga cgagatccgc 4500 ggcatgggcc tgctgatcgg cgcggcgctg accgacgagt ggaagggcaa ggccagggat 4560 gtgctcaacg ccgccgagaa agaggcggtc atggtgctcc aggccagccc ggacgtggtg 4620 cgcttcgcgc cgagcctggt gatcgacgac gccgagatcg acgaaggcct ggagcgcttc 4680 gagcgcgccg tggccaagct ggtccgcggc tgagcgaacc cacggggccc cggcgcaggc 4740 cgggcacccg atgcgacatc ccggagcggc ccgcgccgga gccgggaacc gtgccgccgt 4800 gcgtggcgcg ggatcttccc tgctggacgt tcgaaaccgt ggcacaggaa ggtgccgcgg 4860 tcccgcgcat ggatgcggca atcatcgttg tctgagaaag gagtgacgcc atgttggtga 4920 tgcgccccgc ccaagcggcc gacctgccac aggtgcagcg tctggcggcg gacagcccgg 4980 taggcgtcac gtccttgccg gatgacgccg aacgcctgcg cgacaagatc ctcgcttccg 5040 aggcctcgtt cgccgcggag gtgagctaca acggcgagga aagctatttc ttcgtcctcg 5100 aggacagcgc cagcggcgaa ctggtcggct gctcggcgat cgtcgcctcg gccgggttct 5160 cggaaccgtt ctacagcttc cgcaacgaaa ccttcgtgca cgcctcgcgc tcgctgtcga 5220 tccacaacaa gatccatgtc ctctcgctgt gccacgacct taccggcaac agcctgctga 5280 ccagtttcta cgtacagcgc gacctggtgc agagcgtcta cgccgaactc aactcgcgcg 5340 gtcgcctgct gttcatggcc agccatccgg agcgcttcgc cgacgcggtg gtggtggaga 5400 tcgtcggcta cagcgacgag cagggcgaat cgccgttctg gaacgcggtc gggcgcaact 5460 tcttcgacct gaactacatc gaggcggaaa agctctccgg gctgaagagc cgcaccttcc 5520 tcgccgaact gatgccgcac tatccgatct atgtgccact gttgccggat gccgcccagg 5580 agtccatggg ccaggtccac ccgcgagcgc agatcacctt cgatatcctg atgcgcgaag 5640 gcttcgagac cgacaactac atcgacatct tcgatggcgg cccgaccctg cacgcgcgta 5700 cctcggggat tcgctcgatc gcccagagcc gggtggttcc ggtgaagatc ggcgaggcgc 5760 cgaagagcgg gcgtccatac ctggtcacca acggccagtt gcaggacttc cgcgcggtcg 5820 tgctggacct ggactgggcg cccggcaagc cggtggccct gagtgttgaa gccgccgagg 5880 ccctgggcgt cggcgaaggc gccagcgtgc gcctggtcgc ggtctgaagg agccagtcat 5940 gatcgtacgt cctgttacca gcgccgacct gccggccctg atcgagctgg cgcgtagcac 6000 cggcaccggc ctgaccaccc tgccggccaa cgagcagcgc ctgcagcatc gcgtcagctg 6060 ggccgagaag gccttccgcg gcgaggccga acgcggcgac gccgactacc tgttcgtcct 6120 cgaggacgac gccggcaagg tcgtcggcat ctccgccatc gccggagcgg tggggcttcg 6180 cgaaccctgg tacaactacc gggtcggcct caccgtgagc gcctcgcagg aactcaacat 6240 ccatcgcgag atccccacgc tgttcctggc caacgacctg accggcaatt ccgagctgtg 6300 ctcgctgttc ctccacgccg accaccgcag cggcctcaac ggcaagctgc tgtcgcgcgc 6360 gcgcttcctg ttcatcgccg aattccgcca cctgttcggc gacaagctga tcgccgagat 6420 gcgcggcatg tccgacgagg aggggcgttc gccattctgg gaaagcctcg gccggcactt 6480 cttcaagatg gaattctccc aggccgacta cctcaccggg gtcggcaaca aggccttcat 6540 cgccgagctg atgccgaagt tcccgctcta tacctgcttc ctctccgagg aggcgcgcgg 6600 ggtgatcggc cgcgtccatc cgaacaccga gccggcgctg gccatgctca aggccgaggg 6660 cttcagctac cagggctacg tcgacatctt cgacgccggc ccggcgatcg aggccgagac 6720 cgacaagatc cgcgccatcg ccgagagcca gaacctggtg ctggcggtgg gcactcccgg 6780 cgacgacgcc gagccctacc tgatccacaa ccgcaagcgc gaagactgtc gcatcaccgc 6840 cgcgccggcg cgagccgccg ccggcaccct ggtggtcgat ccgctgactg ccaagcgcct 6900 gcgcctgtcg gccggcgcct cggtacgcgc ggtgccgctg tcggcgcaga agcgcggttg 6960 aaagcctgat ggaggcgtcc cggcgagggc gcccgaggag tcgatgatga gtacccatta 7020 cattgccggc cagtggctgg cgggccaggg cgagaccctg gagtccctcg acccggttgg 7080 ccagggcgtg gtctggtccg ggcgcggcgc tgacgccacc caggtcgacg ctgccgtgtg 7140 cgccgcccgc gaggccttcc cggcctgggc gcggcgcccg ctggagcagc gcatcgagtt 7200 gctcgagcgc ttcgctgcga ccctcaagtc ccgcgccgac gagctggccc gagtgatcgg 7260 cgaggaaacc ggcaagccgc tgtgggagtc ggccaccgaa gtgaccagca tggtcaacaa 7320 ggtggcgatc tcggtgcagg cgttccgcga gcgcaccggc gagaaatccg gtccgctggc 7380 cgacgctacc gccgtgctac ggcacaagcc gcatggcgtg gtggcggtat tcggtcccta 7440 caatttcccc ggccacctgc ccaacgggca tatcgtcccg gcgctgctgg ccggtaactg 7500 cgtggtgttc aagcccagcg agctgacccc gaaggtcgcc gagctgacgc tcaaggcctg 7560 gatccaggcc ggcctgccgg ccggcgtgct caacctggtc cagggcggtc gcgaaaccgg 7620 cgtcgcgctg gccgcccacc gagggctcga cggtctgttc ttcaccgggt ccagtcgcac 7680 cggcaacctg ctgcacagcc agtttggcgg ccagccgcag aaaatcctgg cgctggagat 7740 gggcggcaac aacccgctgg tggtggagga ggtcgccgac ctcgacgccg ccgtctacac 7800 catcatccag tccgccttca tctccgcagg ccagcgttgc acctgcgccc gccgcctgct 7860 ggtgccgcag ggcgcctggg gcgacgcact gctggcgcgc ctggtggcgg tcagcgctac 7920 cctgcgggtc ggtcgcttcg acgaacagcc ggcgccgttc atgggcgcgg tgatttcgct 7980 gagcgccgcc gagcacctgc tcaaggccca ggagcatttg atcggcaagg gcgcacagcc 8040 gctgctggcg atgacccagc cgatcgacgg cgccgccctg ctgaccccgg gcatcctcga 8100 cgtcagcgcg gtggccgagc gaccggacga agagttcttc gggccgctgt tgcaagtgat 8160 ccgctactcc gatttcgctg cggcgatccg tgaagccaac gccacccagt acggcctggc 8220 cgccgggttg ctgtcggatt cccgcgagcg tttcgagcag ttcctcgtgg aaagccgcgc 8280 cggcatcgtc aactggaaca agcagctcac cggcgccgcc agcagcgcgc cgttcggcgg 8340 tatcggcgcg tccggcaacc accggccgag cgcctactac gccgccgatt actgcgccta 8400 tccggtcgcc tcgctggaaa gccccagcgt gtcccttcct gccaccctga ctcccgggat 8460 cagcctatga atgcccatga agtgaatttc gacggcctgg tcggcccgac ccacaactac 8520 ggcggcctgt cctacggcaa tgtcgcttcg caaagcaaca gccaggcggt gtccaacccg 8580 aaggaagcgg cgaagcaggg cctggcgaag atgaaggcgc tgatggagat gggtttcaag 8640 cagggggtac tcgctccgca agcccgcccg gataccgctg cgctgcgtag cctgggcttc 8700 tccggcagcg acgaggaggt gatccgccgt gcggcgaagg aagcgatgcc tctcctagcc 8760 gcctgcagct cggcgtcgag catgtggacc gccaatgccg ccacggtcag cccgagtgcc 8820 gacaccgccg acggccgcgt gcatttcacc gcggccaacc tgaactgcaa gttccaccga 8880 tccatcgagc atcccaccac cagccgcgtg ctggcggcga tgttcaacga cgagcggcat 8940 ttcgcccatc acgcggcgct gccggcagtg agccagttcg gcgacgaagg cgcggccaac 9000 cacacgcgct tctgcaagga ctatggcgat gccggcgtgg agttcttcgt cttcggtcgc 9060 agcgccttcg acagtcgctt cccggcgccg caacgctatc cggcgcgcca gaccctggaa 9120 gcctgccagg ccgtcgcgcg tctgcacggg ctgagcgagg ccggagtggt ctacgctcaa 9180 cagaacccgg cggtgatcga ccagggcgtg ttccacaacg atgtgatctc ggtgggcaat 9240 ggcgaggtgc tgttccatca cgaggacgcc ttcctcgata ccgagaaggt ccttgccgaa 9300 ctgcacgaca agctgggccg ccgcggcggc cgcttccgcg ccatctgcgt cccgcgcgac 9360 caggtcgcgg tggaggacgc ggtgaagtcc tacctgttca acagccaact gctgtcgaag 9420 gccgacggtt cgatgctgct ggtggtaccg gaggagtgtc ggaacaaccc gcgggtctgg 9480 aactacctgg accagctcac cggcgacgac ggtccgatcc gcgaagtgaa ggtcttcgac 9540 ctcaagcaga gcatgcagaa cggcggcggt ccggcttgcc tgcgcttgcg cgtggcgctg 9600 caggaacggg agctggcggc ggtgaatccg ggggtgatca tgagcgccgg cctgtacgac 9660 acgctggtag cctgggtcga ccggcactac cgcgaccgcc tgagcgagac cgacctggcc 9720 gacccccaac tgctgctgga gtgccggacg gcattggatg aactgacgca gatccttaaa 9780 ctgggctcgg tttattcctt ccaactcgat tgagagcctc gccaccatgt ccgatagcct 9840 gcaactgatc ctcgaagata ccgacggcac ccagctggaa acttcctgca cccgtttcgc 9900 cgtggtctgg cagggcaagg aagtgtgggt ccagcaagcc ggcaacggcc agttgctgat 9960 cggcgtcgac gtcgaagacg gcgataccga atacaccaac ctgctgctgc ggccgatggc 10020 gaccaacctg gtcagcctgc aactggagat ggagccgatc gaagagggcg acgaccacga 10080 gcacggcccc gactgcggct gcgaccacac ccactgactg aggacatccc atgctcgccc 10140 tcggcaaact gctcgacttg accctggccg gccgcgagcc gaccgagaag atccagctca 10200 ccgccgacgg cacccgcctg cactggctgg ccgagggcgc gctggaagtc acgccgatcg 10260 gcgcccgcga taacggcgtc gacctgttgc tctcggccgg tatccacggc aacgagaccg 10320 cgcccatcga actgctcgaa cggctgatcc gcaaggtcgc cgctggcacc ctcaagcctg 10380 ccgccagggt cctcttcctg ttcggcaacc ccgaagccat ccgccgcggc gagcgctacg 10440 tcgaacagga catgaaccgc ctgttcaacg gtcgccacga ggagggcagt ggcaacgagg 10500 ccttccgtgc cgccgagctg gagcgcctgg cccaggtgtt cttcagcaag accgagcgag 10560 tccacctgca ctacgacctg cataccgcga tccgcggctc gaagatcgag cagttcgccc 10620 tctacccctg ggccgagggc cgccagcatt cccgcagcga actggcccgc ctgcgcgacg 10680 ccggcatcga ggcggtgctg ttgcagaaca agccgggcat caccttcagc gcctacacct 10740 acggccagct cggcgccgag gcctttaccc tggaactggg caaggcacgt ccgttcggag 10800 agaaccagga ggtcaacctg gagcgcctgg agcggagcct ggagctgctg atcgacggca 10860 gcgaggaaca gccggacggc tcccggctcg acggcctcaa gctgttcagc gtgtcgcgcg 10920 aggtgatcaa gcacagcgac cacttccgcc tgcacctcga cgacgacgtg gccaacttca 10980 ccgaactctc gccgggctac ctgctggccg aggatatcgg cggcacgcgc tgggtggtgg 11040 acgaggtcgg cgcgcgcatc atcttcccca atccacgggt gaagaacggc ctgcgtgccg 11100 gaatcctggt ggtgccggcc aagctctgag gcgtatcggc cttccctctc gatcatgacg 11160 gagcgcttcg gcgctccgtt tccgttgcgg ccgggaagat ttcccgactt cccttgtggc 11220 tgtcggtaga gcgccgtagg atcgggcttt tccgccgaac cgaggagccc tccgtgcctg 11280 tcatcgacct gcgcagcgac accgtcaccc agcccaccgc cggcatgcgc gaagccatgg 11340 ccgcggccga actgggcgac gacgtctatg gcgaggaccc cacggtcaac cgcctggagg 11400 ccgaactggc ggcgcgcctg ggcttcgccg cggcgctctt cgtaccgacc gggaccatga 11460 gcaacctgct cggattgatg gcccactgcg agcgcggcga cgaatacatc gtcggccagc 11520 aggcgcatac ctacaaatac gagggcggcg gtgccgcggt gctgggctcg atccagccgc 11580 agccgatcga cggcgaggcc gacggatcgc tccacctgga caaggtcgcg gcggcgatca 11640 aggccgacga tttccacttc gccaggaccc gcctgctggc cctggaaaac accatgcagg 11700 gcaaggtgct gccgctcgac tacctggccg cggcgcgcgc cttcactcgc gcgcgtggcc 11760 tggccctgca cctggatggc gcgcgcctgt acaacgcggc ggtgaagctg ggcgtagacg 11820 ccagcgagat cacccgacac ttcgactcgg tgtcggtgtg cctgtccaag ggcctcggtg 11880 cgccggtggg ctcggtgctt tgcggcagcg tcgaactgat cggcaaggcc cgccgctggc 11940 gcaaaatggt cggcggcggg atgcgccagg ccggcctgtt ggcggctgcc ggactgtacg 12000 ccctcgacca ccaggtggca cgcctggccg acgaccacgc caacgccgcg cgcctgggcg 12060 acgggctgcg cgaactgggc tatgcggtgg agccggtgca gaccaacatg gtctacgtcg 12120 atgtcggcga gcgggcggtc gcgctgcgcg acttcctcgc cgagcgcggg gtgcggatca 12180 gcgcggcggc gcgtttgcgc ctggtcaccc acctggacgt ttccgccgag tccataggac 12240 aagtactgga tgccttcgcg gcctttcgtc gctcataagc gaaaaggtcg gcaataggca 12300 ataactatcg cgcaaataca ctacaacctt gcccaagggc cgatataatg cggccctttg 12360 ccggcgattc gtggccgcca attttccgtg gaagaaccta tgaaaagcgc tgaaatccgt 12420 gaagccttcc tccgcttctt cgaagagaag ggacacaccc gtgtcgcttc cagttcgctg 12480 atcccggcga acgatccgac cctgctgttc accaacgcgg gcatgaacca gttcaaggac 12540 tgcttcctcg gcctggaaaa gcgcgcctac acccgtgcga ccaccagcca gaaatgcgtg 12600 cgcgccggcg gcaagcacaa cgacctggaa aacgtcggct acaccgcgcg gcaccacacc 12660 ttcttcgaaa tgctgggtaa cttcagcttc ggcgactatt tcaagcgcga cgccatccat 12720 tacgcctggg agttcctcac cggcgagaaa tggctgaacc tgcccaagga aaagctctgg 12780 gtcaccgtct acgccaccga cgacgaggcc tacgacatct ggaccaagga agttggcgtg 12840 cccgccgagc gtatggtgcg gatcggcgac aacaagggcg cgccctatgc gtccgacaac 12900 ttctgggcga tgggcgatac cggaccctgc ggtccctgca ccgagatct 12949 // |
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