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EBI DbfetchID AF008440; SV 2; linear; mRNA; STD; MAM; 2430 BP. XX AC AF008440; XX DT 11-SEP-1997 (Rel. 52, Created) DT 16-AUG-2001 (Rel. 68, Last updated, Version 2) XX DE Sus scrofa steroid 5-alpha-reductase 2 (ST5AR2) mRNA, complete cds. XX KW . XX OS Sus scrofa (pig) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus. XX RN [1] RP 1-2430 RA Men T., Houde A., Murphy B.D.; RT ; RL Submitted (13-JUN-1997) to the EMBL/GenBank/DDBJ databases. RL Agriculture and Agri-Food Canada, Food Research and Development Center, RL Food Research and Development Center, St.-Hyancinthe, Quebec JS2 8E3, RL Canada XX RN [2] RC Sus scrofa steroid 5-alpha-reductase 2 (ST5AR2) mRNA, complete cds RP 1-2430 RA Lacroix D.A., Men T., Houde A., Murphy B.D.; RT ; RL Submitted (22-AUG-2000) to the EMBL/GenBank/DDBJ databases. XX CC On Aug 15, 2001 this sequence version replaced gi:2352804. XX FH Key Location/Qualifiers FH FT source 1..2430 FT /organism="Sus scrofa" FT /mol_type="mRNA" FT /sex="male" FT /tissue_type="epididymus" FT /db_xref="taxon:9823" FT CDS 42..806 FT /codon_start=1 FT /gene="ST5AR2" FT /product="steroid 5-alpha-reductase 2" FT /function="converts testosterone into FT 5-alpha-dihydrotestosterone" FT /function="converts progesterone or corticosterone into FT their corresponding 5-alpha-3-oxosteroids" FT /EC_number="1.3.99.5" FT /note="type 2; 4-ene-3-oxosteroid 5-alpha oxidoreductase; FT reduced or excessive levels can cause incomplete FT differentitation of male external genitalia, prostate FT cancer, and female hirsutism in Homo sapiens; expressed at FT high levels in androgen-sensitive tissues" FT /db_xref="GOA:O18765" FT /db_xref="InterPro:IPR001104" FT /db_xref="UniProtKB/Swiss-Prot:O18765" FT /protein_id="AAB69279.2" FT /translation="MPVRCQQSPVLAGSATLAALGALALYFAEPSGYGKYTESLTPAAI FT RLPARAAWFLQELPSFVVPAGILAGQPRSLFGPPATVLLGLFCAHYFHRTFVYSLLTRG FT RPFPVVFLFRGFVFCMGNGLLQGYYLVYCAEYPAEWYTDIRFSLGVFLFILGMGINIHS FT DYILRQLRKPGEVIYKIPQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLC FT FLGLRAFHHHRFYVKMFEDYPKSRKALIPFIF" XX SQ Sequence 2430 BP; 613 A; 555 C; 550 G; 711 T; 1 other; tctctgctct gtcggaagcc actggcgggg aatacggcgc gatgcctgtt cgctgccagc 60 agagcccggt gctggcgggc agcgccactt tggctgccct gggggcactg gccctgtact 120 tcgcggagcc ctctggctac gggaagtaca cggagagcct gacgcccgcg gctatccgcc 180 tgccagcccg tgccgcctgg ttcctgcagg agctgccctc cttcgtggtg cccgcgggga 240 tcctcgccgg gcagccccgt tctctcttcg gcccgcctgc gactgtgctt ctgggcctct 300 tctgcgcaca ttacttccac aggacatttg tttactcact gctcactaga gggaggcctt 360 ttccagttgt attccttttc agaggctttg tcttctgcat gggaaatgga ctccttcaag 420 gctactatct ggtttactgt gccgaatacc ctgctgagtg gtacacagac atacggttta 480 gcctaggtgt gttcttattt attttgggca tgggaatcaa cattcacagc gactatatat 540 tgcgccagct caggaagcct ggagaagtca tctataagat tccacaaggt ggcttgttca 600 cgtacgtttc tggagccaat ttccttggtg agatcattga atggatcggc tatgccttgg 660 ccacttggtc ccttccagca cttgcatttg catttttctc gctttgtttc cttgggctgc 720 gagcttttca ccatcatagg ttctacgtca agatgtttga ggactacccc aagtctcgaa 780 aagcccttat tccatttatc ttttaaagaa accaaataaa aaaaggaaca aagtccccac 840 aatcttgttg aagaaccttc aagctgcgga acctgtaact tttcaagtcc cactgtgtat 900 gtgtaataat cagcctctgg tgttctggca ggtggcctga ggattctgca cgggacccct 960 tagtgtttcc tcgaaccctc tctgcgggtc tctatcctga tttcctatta aaacttccac 1020 aaggtctgct tttatgcaga ggtatctgtt tcttagctct tcctcctaga aagtgtatac 1080 ttccctttgt atttttttct ctgaatggcc caagtccatg tgactttata tctatgctgt 1140 gtcagtataa gacagctctg tatttgagag tgttttgagt tgagggcagt gcttacggaa 1200 tttatttaag gtacacagtt aacacttatg cagaccagca gagatttaaa ttgtaaagct 1260 gcacagaccc agagcaaatc tcctccgaaa tgaaaaccct gtcatatctt ccttttcctc 1320 agttaattat gaaagatgta acaagaataa gttgactctt caaggaggcg tcttctcttc 1380 atatggctga aaatgcagtg atgcattgac tccgtttcaa atctgtgcgg tcttagtgcc 1440 tctgtcttcc tgaagatttc acagtccctg ttagagatat agtctaacgt agaaaactgg 1500 ggtgggtttt tgctgaaggt caggttttaa caaccaagaa gtcatgactc tggttgccta 1560 ccgagggaga gtgaaaatgg gttgcgtaaa caccctacaa caccctcttt tctcggaaac 1620 cagcggatac attgaaacaa tgaaagtgtc agataatgga aattgccaag taagagcatg 1680 tgctggtgcc ccaaggagac agataccatg actgaagcat ctcagaagca acccttccct 1740 tctggagttt ctgcttcaca gtcctcagga tctgatcaag aaggagttct cctaggagcg 1800 ccttgaactt cagtcctcaa aagtcctggg ggcagaggct gaaaactgca accagaggga 1860 tgcctctggg cagaaacctg ttttctttga ctcgacagtg tttcacacat agtttttttt 1920 ttgttttgtt ttatgttcag agtttccaaa atttaaaaat taggtaattt ctacactttc 1980 tagttttctt aaaaaagtcg gaggatctgg gcctgtagaa cctgctaaga actgggactg 2040 atcagctgat acacacgagc atttgcaact ttgaagaggc ggggtcgtat gagtgctgag 2100 actttggact ctctaaagaa ggggttgaac actcataatc agaatgaaca acagtatttg 2160 tctctgtagg cccaggttgg gttggtaata tttaacaaag ccttttgaga aatgagcncc 2220 agttttatca gctgcagtgc taagtccagg aattaactgt ataagacata taggacactc 2280 aaaatatctg aagacgatgt caatcactga aaaatacaga ctgtaatcat ataaatacat 2340 gttttgctgt ttattaaatg cctctcatat catggatgtt aaataatttt tttgaattaa 2400 aagatcccag aatgcaaaaa aaaaaaaaaa 2430 // |
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