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EBI DbfetchID AF006039; SV 1; linear; genomic DNA; STD; PRO; 2695 BP. XX AC AF006039; XX DT 05-JUL-1997 (Rel. 52, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Helicobacter pylori phosphoserine phosphatase (serB) gene, partial cds, and DE alpha-(1,3)-fucosyltransferase (fucT) gene, complete cds. XX KW . XX OS Helicobacter pylori OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; OC Helicobacteraceae; Helicobacter. XX RN [1] RP 1-2695 RX DOI; 10.1074/jbc.272.34.21349 RX PUBMED; 9261148. RA Martin S.L., Edbrooke M.R., Hodgman T.C., van den Eijnden D.H., Bird M.I.; RT "Lewis X biosynthesis in Helicobacter pylori. Molecular cloning of an RT alpha(1,3)-fucosyltransferase gene"; RL J. Biol. Chem. 272(34):21349-21356(1997). XX RN [2] RP 1-2695 RA Martin S.L., Edbrooke M.R., Van den Eijnden D.H., Bird M.I.; RT ; RL Submitted (29-MAY-1997) to the EMBL/GenBank/DDBJ databases. RL Glycobiology, GlaxoWellcome Medicines Research Centre, Gunnels Wood Road, RL Stevenage, Herts. SG1 2NY, UK XX FH Key Location/Qualifiers FH FT source 1..2695 FT /organism="Helicobacter pylori" FT /strain="NCTC 11637" FT /mol_type="genomic DNA" FT /db_xref="taxon:210" FT CDS <1..523 FT /codon_start=2 FT /transl_table=11 FT /gene="serB" FT /product="phosphoserine phosphatase" FT /EC_number="3.1.3.3" FT /db_xref="GOA:O32630" FT /db_xref="HSSP:1J97" FT /db_xref="InterPro:IPR005834" FT /db_xref="UniProtKB/TrEMBL:O32630" FT /protein_id="AAB93986.1" FT /translation="ITLKAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGAF FT ELISTLKEKNYKVVCFSGGFDLATNHYRDLLHLDAAFSNTLVVENNALNGLVTGHMMFS FT HSKGEMLLALQRLLNISKTNTLVVGDGANDLSMFKHAHIKIAFNAKEVLKQHATHCINE FT PDLALIKPLI" FT CDS 925..1926 FT /codon_start=1 FT /transl_table=11 FT /gene="fucT" FT /product="alpha-(1,3)-fucosyltransferase" FT /function="GDP-fucose + Gal-beta-(1,4)-GlcNAc-R = GDP FT +Gal-beta-(1,4)-[Fuc-alpha-(1,3)]-GlcNAc-R" FT /EC_number="2.4.1.-" FT /note="may catalyze alpha-(1,3)-fucosylation of FT Gal-beta-(1,4)-GlcNAc repeats in H. pylori LPS; involved in FT cell surface expression of Lewis X epitope." FT /db_xref="GOA:O32631" FT /db_xref="InterPro:IPR001503" FT /db_xref="UniProtKB/TrEMBL:O32631" FT /protein_id="AAB93985.1" FT /translation="MPLYYDRLHHKAESVNDTTAPYKIKGNSLYTLKKPSHCFKENHPN FT LCALINNESDPLKRGFASFVASNANAPMRNAFYDALNSIEPVTGGGAVKNTLGYKVGNK FT SEFLSQYKFNLCFENSQGYGYVTEKIIDAYFSHTIPIYWGSPSVAKDFNPKSFVNVHDF FT NNFDEAIDYVRYLHTHPNAYLDMLYENPLNTLDGKAYFYQNLSFKKILDFFKTILENDT FT IYHNNPFIFYRDLNEPLVSIDNLRINYDNLRVNYDDLRVNYDDLRVNYDDLRINYDDLR FT INYDDLRINYERLLQNASPLLELSQNTSFKIYRKIYQKSLPLLRVIRRWVKK" XX SQ Sequence 2695 BP; 840 A; 483 C; 534 G; 838 T; 0 other; gatcactttg aaagctatga atggcgagac agattttcat aaaagtctta ttttaagggt 60 ttccaaactc aaaaacatgc ccttaaaact agccaaagaa gtttgtgaaa gtctgccttt 120 atttgagggg gcgtttgaac tcattagcac cttaaaagag aaaaattaca aggtggtttg 180 cttcagcgga ggctttgatc tagcgaccaa tcattacagg gatttattgc atttagatgc 240 ggctttcagt aacacgctgg tagtggaaaa taacgcctta aacggcttgg ttacggggca 300 tatgatgttt tcacactcta aaggcgaaat gctactcgct ttacaacgct tattaaatat 360 cagtaaaacg aacactttag tcgtgggcga tggggcgaat gacttgagca tgttcaaaca 420 tgcccatatt aaaatcgctt tcaacgctaa agaggtttta aaacagcacg ctacgcattg 480 catcaatgag cctgatttag ccctaatcaa gcctttgatt taaaaaaatt tttttgtaaa 540 atactccttt taaaggataa ccatgttcca acccctatta gacgccttta tagaaagcgc 600 ttccattgaa aaaatggcct ctaaatctcc ccccccctaa aaatcgctgt ggcgaattgg 660 tggggagatg aagaaattaa agaatttaaa aagagcactc tgtatttcat tttaagtcag 720 cattacacaa tcactttaca ccgaaaccct gataaacctg cggacatcgt ttttggtaac 780 ccccttggat cagccagaaa aatcttatcc tatcaaaaca ctaaacgaat attttacacc 840 ggtgaaaacg aatcgcctaa tttcaacctc tttgattacg ccataggctt tgatgaatta 900 gactttagag atcgttattt gagaatgcct ttatattatg ataggctaca ccataaagcc 960 gagagcgtga atgacaccac cgcaccctac aagattaaag gcaacagcct ttatacttta 1020 aaaaaaccct cccattgttt taaagaaaac caccctaatt tgtgcgcgct catcaataat 1080 gagagcgatc ctttgaaaag agggtttgcc agttttgtag cgagcaacgc taacgctcct 1140 atgaggaacg ctttctatga cgctttaaat tctattgagc cagttactgg gggaggagcc 1200 gtgaaaaaca ctttaggcta taaggttgga aacaaaagcg agtttttaag ccaatacaaa 1260 ttcaacctgt gttttgaaaa ctcacaaggc tatggctatg taaccgaaaa aatcattgac 1320 gcttacttta gccatactat tcccatttat tgggggagtc ccagcgtggc gaaagatttt 1380 aaccctaaga gttttgtgaa tgtccatgat ttcaacaact ttgatgaagc gattgattac 1440 gtgagatact tgcacacgca cccaaacgct tatttagaca tgctctatga aaacccttta 1500 aacacccttg atgggaaagc ttacttttac caaaatttga gttttaaaaa aatcctagat 1560 ttttttaaaa cgattttaga aaacgacacg atttatcata ataacccttt cattttctat 1620 cgtgatttga atgagccgtt agtatccatt gataatttga gaatcaatta tgataatttg 1680 agggttaatt atgatgattt gagggttaat tatgatgatt tgagggttaa ttatgatgat 1740 ttgagaatca attatgatga tttgagaatc aattatgatg atttgagaat taattatgag 1800 cgccttttgc aaaacgcttc acctttattg gaattgtccc aaaacacctc ttttaaaatc 1860 tatcgcaaaa tttatcaaaa atccttaccc ttattgcgtg taataaggag gtgggttaaa 1920 aaataaggcg ttttttaaga ctgattaaga aactgaacgc tattttaaaa tgcgctaacg 1980 cttctttttt tgagcgtggg gtttttgagc atgtcctcta aagcatgggt gcttaaaaaa 2040 tgttttgttt ttaaagacac gatgcgccca aaggactctt ctttaaaaag gtttaaaagg 2100 cgtttgggca aaatctcgcc aaataccaca atgacttttg aagcgctgtt gtctaattgc 2160 caggttaaat gaaataggca tgcgttgatt tcttcttcta aattaaggct gttagagtcg 2220 catttaagga gcgataaaat actgcaatct tttaaggggt agttaaaaac cttttggata 2280 atgctctcta acatggctgc ttttaaattg tttaagaaat ttaattggct atccagcata 2340 ggggtgagcg tgatgaaagc gagcttggaa gtggggttaa aaagcccaat caccggtttt 2400 gaatgttgat ggcgtttgca cagattgcaa ttttctatgc cctcatgaac ttgttctgtt 2460 aaggggctta ttttgaggct tggtaaggct agtattggtg taagtttcgc ccaaaagacg 2520 ctccatataa agagagcgta aagtttgaag gcgtgagtgt tgcaaagcgt tcagtcttta 2580 tgctttttga aagcgtgagg gcttagcatg ttttctggct tgaaaatatc gtccagttgc 2640 tctttagtta agattttctt ttctaaagcg atgtcataga tagaacgatc gcttt 2695 // |
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