 |
|
EBI DbfetchID AB047926; SV 1; linear; genomic DNA; STD; PRO; 9244 BP. XX AC AB047926; XX DT 04-APR-2001 (Rel. 67, Created) DT 14-APR-2005 (Rel. 83, Last updated, Version 2) XX DE Thermoactinomyces vulgaris gene cluster for dextrin utilization, complete DE and partial cds. XX KW . XX OS Thermoactinomyces vulgaris OC Bacteria; Firmicutes; Bacillales; Thermoactinomycetaceae; OC Thermoactinomyces. XX RN [1] RP 1-9244 RA Pi Y.; RT ; RL Submitted (30-AUG-2000) to the EMBL/GenBank/DDBJ databases. RL Yo Pi, Tokyo University of Agriculture and technology, Department of RL applied Biological science; Saiwai-cho 3-5-8, Fuchu, Tokyo 183-8509, Japan RL (E-mail:yopi@cc.tuat.ac.jp, Tel:81-42-367-5704, Fax:81-42-367-5704) XX RN [2] RA Pi Y.; RT "A gene Cluster for Dextrin Utilization from Thermoactinomyces vulgaris RT R-47"; RL Unpublished. XX RN [3] RX PUBMED; 7763540. RA Tonozuka T., Ohtsuka M., Mogi S., Sakai H., Ohta T., Sakano Y.; RT "A neopullulanase-type alpha-amylase gene from Thermoactinomyces vulgaris RT R-47"; RL Biosci. Biotechnol. Biochem. 57(3):395-401(1993). XX RN [4] RX DOI; 10.1016/0167-4838(95)00101-Y RX PUBMED; 7548164. RA Tonozuka T., Mogi S., Shimura Y., Ibuka A., Sakai H., Matsuzawa H., RA Sakano Y., Ohta T.; RT "Comparison of primary structures and substrate specificities of two RT pullulan-hydrolyzing alpha-amylases, TVA I and TVA II, from RT Thermoactinomyces vulgaris R-47"; RL Biochim. Biophys. Acta 1252(1):35-42(1995). XX CC A chromosomal region about 9 kilobase DNA fragment from CC Thermoactinomyces vulgaris R-47 including TVA II gene encoding CC Alpha-amylase II, was cloned and the nucleotides were determined. CC The nucleoide sequences data of TVA II and TGA genes have been CC previously deposited in GenBank with accession numbers D13178 and CC AB029554, respectively. The sequence fragment gene located CC upstream of the TVA II gene was determined on both strand CC (published only in Database). Its consisted of 5080 bp and CC revealed the existence of five completely open reading frames. CC This reported these open reading frame as ORF-1,ORF-2, ORF-3, CC ORF-4 and ORF-5, all of genes except ORF-4 were transcribed in the CC same direction. XX FH Key Location/Qualifiers FH FT source 1..9244 FT /organism="Thermoactinomyces vulgaris" FT /strain="R-47" FT /mol_type="genomic DNA" FT /db_xref="taxon:2026" FT CDS 1..372 FT /codon_start=1 FT /transl_table=11 FT /gene="orf-5" FT /product="peptide methionine sulfoxide reductase-homolog FT protein" FT /note="ORF-5, peptide methionine sulfoxide FT reductase-homolog protein" FT /db_xref="GOA:Q9AJF7" FT /db_xref="HSSP:1FVA" FT /db_xref="InterPro:IPR002569" FT /db_xref="UniProtKB/Swiss-Prot:Q9AJF7" FT /protein_id="BAB40633.1" FT /translation="MATFGAGCFWGVEETFRQVPGVIDTAVGYMGGTTENPTYEEVCTD FT KTGHAEVVQVEYDPEQVSYEELLNVFWDNHNPTTLNRQGPDVGTNIARLFFTTLKSKEI FT PQKNPKRKWIKAGVGKIRL" FT CDS complement(527..1327) FT /codon_start=1 FT /transl_table=11 FT /gene="orf-4" FT /product="ATP-binding protein-homolog" FT /note="ORF-4, ATP binding protein-homolog" FT /db_xref="GOA:Q9AJF6" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q9AJF6" FT /protein_id="BAB40634.1" FT /translation="MIIEMNSVSWMREGKMILKNISWQVQPGENWCLIGLNGSGKTTLL FT NLVNGYIWPTTGTVKLFGKKFGEVNLRELRKKIGWVSSSLAQQLHNHETAINIVLSGKF FT ASIGLYDKPEKIDMEKAAALLEMMGCGHLITQTYQTLSQGEKQKVLIARALMASPQLMI FT LDEPCTGLDLFAREQLLHSIQSISAHPQSPALIYVTHHVEEITNCFTHTLLLKQGEIFR FT AGPTSHVLTEELLSDFFDTPIEVEHRGKRCWIRPLEPSRPLSIQ" FT CDS 1557..2810 FT /codon_start=1 FT /transl_table=11 FT /gene="orf-3" FT /product="periplasmic binding protein" FT /note="ORF-3, E. coli MalE- homolog protein" FT /db_xref="GOA:Q9AJF5" FT /db_xref="InterPro:IPR006060" FT /db_xref="PDB:2ZYK" FT /db_xref="UniProtKB/TrEMBL:Q9AJF5" FT /protein_id="BAB40635.1" FT /translation="MRKFLSLALISALVIGLLTACGPKRDPYAKAGKSEGKPDKLVVWE FT NADDGVQLNNTKKWAGEFTKKTGIQVEVVPVALLKQQEKLTLDGPAGKGADLVTWPHDR FT LGEAVTKGLLQPIQVDNSVKNQFDDVAMKALTYGGKLYGLPKAIESVALIYNKKLMGQV FT PATYDELFQYAKANNKPDEQKYGVLFEANNFYYTYFLFAAKGAAVFKEQDGTLDPNEIG FT LNSPEAVQGMNEVQKWFTEARLPQSLKADTVNGLFKSGKVAAVINGPWAIKDYQAAGIN FT VGVAPLPKIDGKDAQTFIGVKGWYLSAYSKYPKYATELMQFLTSKEALASRFKETGEIP FT PQKELLNDPMIKNNPVVNGFAKQASKGVPMPSIPEMGVVWEPINNAHTFVAQGKQTPEQ FT ALNDAVKIMKEKIQTMKQ" FT CDS 2994..4217 FT /codon_start=1 FT /transl_table=11 FT /gene="orf-2" FT /product="inner membrane protein ORF-2" FT /note="ORF-2, E. coli MalF-homolog protein" FT /db_xref="GOA:Q9AJF4" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9AJF4" FT /protein_id="BAB40636.1" FT /translation="MGLGQMYNGQWVKGVLFLVCRLSYLLVFYDLFNLGLWGIVTLGTI FT PGVDNSMELLAEGLISLLLILFGLFFYGLNIRDAYKVGAMRERGIRPPGVMETCRHVTD FT RGFPYFVMAPSMILLMFIVLFPILFMVTIAFTNFDLYHQPPAKLVSYVGVDNFINLFRL FT SFWKNSFLGVLSWTVVWTLVSTTVQVALGLFLAVLLNQKRLRIKKFFRTVLILPWAVPS FT FVTILVFSGLFDDNFGPVNHFLVALGLKAIPWMSDPFWCKVAVLLIQFWLGFPFSLALY FT TGVLQSISRDLYEAAEVDGATVWQKFRHITLPMALYSTAPLLIVQYAGNFNNFNVIYLF FT NKGLPAVPGQTAGGTDILISWVYKLTFETSKYNYAAAISIMIGLIVAVLAVWQFRNTRS FT FKEEGMIQ" FT CDS 4277..5059 FT /codon_start=1 FT /transl_table=11 FT /gene="orf-1" FT /product="inner membrane protein ORF-1" FT /note="ORF-1, E. coli malG-homolog protein" FT /db_xref="GOA:Q9AJF3" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q9AJF3" FT /protein_id="BAB40637.1" FT /translation="MAVLSVYPVLWVIGASFSPGDTIFSTSLIPKHATLDHYKWLFFNP FT DSQYPTWYLNTLKIALINGVVSVLITTGTAYVFSRYRFAGRQYGLMSFLILQMFPSTMT FT MVAIYLLLNMLHLLDTHLGLLLFYAGTQIPFNTWLVKGYFDTIPHSLDEAARIDGAGHL FT TIFWKVILPLAKPILAVVFLFNFMGPMTDFLLPQIILTSPEHQTLAVGLFSFINDDFKK FT QYTLFAAGSVLIALPITVIFLSLQRCFISGLTAGASKG" FT CDS 5080..6837 FT /codon_start=1 FT /transl_table=11 FT /gene="tva II" FT /product="alpha-amylase TVA II" FT /function="alpha-amylase" FT /note="ORF-0" FT /db_xref="GOA:Q7DI93" FT /db_xref="InterPro:IPR013781" FT /db_xref="UniProtKB/TrEMBL:Q7DI93" FT /protein_id="BAB40638.1" FT /translation="MLLEAIFHEAKGSYAYPISETQLRVRLRAKKGDVVRCEVLYADRY FT ASPEEELAHALAGKAGSDERFDYFEALLECSTKRVKYVFLLTGPQGEAVYFGETGFSAE FT RSKAGVFQYAYIHRSEVFTTPEWAKEAVIYQIFPERFANGDPSNDPPGTEQWAKDARPR FT HDSFYGGDLKGVIDRLPYLEELGVTALYFTPIFASPSHHKYDTADYLAIDPQFGDLPTF FT RRLVDEAHRRGIKIILDAVFNHAGDQFFAFRDVLQKGEQSRYKDWFFIEDFPVSKTSRT FT NYETFAVQVPAMPKLRTENPEVKEYLFDVARFWMEQGIDGWRLDVANEVDHAFWREFRR FT LVKSLNPDALIVGEIWHDASGWLMGDQFDSVMNYLFRESVIRFFATGEIHAERFDAELT FT RARMLYPEQAAQGLWNLLDSHDTERFLTSCGGNEAKFRLAVLFQMTYLGTPLIYYGDEI FT GMAGATDPDCRRPMIWEEKEQNRGLFEFYKELIRLRHRLASLTRGNVRSWHADKQANLY FT AFVRTVQDQHVGVVLNNRGEKQTVLLQVPESGGKTWLDCLTGEEVHGKQGQLKLTLRPY FT QGMILWNGR" FT CDS 6909..8864 FT /codon_start=1 FT /transl_table=11 FT /gene="tga" FT /product="glucoamylase TGA" FT /function="glucoamylase" FT /note="ORF +1, glucoamylase (TGA)" FT /db_xref="GOA:Q9KWR2" FT /db_xref="InterPro:IPR012341" FT /db_xref="UniProtKB/TrEMBL:Q9KWR2" FT /protein_id="BAB40639.1" FT /translation="MANKRYLIDAVIGNDKILAVLDRYGELHRLWWPQKDYAQHVNRLS FT AGVLIPGKSKGVWWFHQPAGKHEQTYVHDAPILRTTATCREWPLEVVCEDEVVSGRNVL FT MRHYVITNCGEEEIPLQFVSYTSFHMGEMKRYNTTLFVGKKEALVHYRREFAVAVGSVL FT PTTRFAAGSNKDHIDQGLFNCNDIAMHTDGGCLWELGLCPPGESKCMTLFFAFGKTVEK FT ALEELEEARTLGFERLRSQTLADWEAYFGQAKPVQTGCEEMDRLYRRSLAVFRLMTDGE FT YGSMIAGPEFDEDFVRCGGYAYCWGRDAAYIATAIDRAGYHDRVRAFYRWAMQTQSRDG FT SWQQRHYLDGRLAPQWGLQIDETGSILWGMWQHYLLTNDRAFLDEIWESVQKAAQFLIL FT FIDPETGLPLPSRDLWEEREGEHTYSASAVCGGLDAAAAVADKLGEKRLAQNWKEAAGA FT IRRAVEEKCWDPERQVFYRGLKLMVPPEEWAHAEKEGKRGMIHVDEKGISRPMLWQDPV FT IDISLVGISVPFNLIAPDDERMVKMAEAIETHLTSPIVGGIKRYENDPYVGGNPWILTT FT LWLAQLYIKQGRIKKALNHLKWVVDHRTDLDLLPEQVDRETGKAAWVVPLTWSHAMFVL FT TVLDLLEIGAIGPKKS" FT CDS 9085..>9244 FT /codon_start=1 FT /transl_table=11 FT /gene="orf+2" FT /note="ORF +2, similar to sugar metabolic operon repressor FT (E. coli MalI)" FT /db_xref="GOA:Q9KWR1" FT /db_xref="HSSP:1PRU" FT /db_xref="InterPro:IPR000843" FT /db_xref="UniProtKB/TrEMBL:Q9KWR1" FT /protein_id="BAB40640.1" FT /translation="MATIKDVAKLAAVSPSTVSRVIAGSNRISLETKQRVQKAMEELNY FT VPNAIARS" XX SQ Sequence 9244 BP; 2293 A; 1951 C; 2598 G; 2402 T; 0 other; atggcaactt ttggggccgg atgtttttgg ggagtggaag aaacgttccg ccaagttccg 60 ggggtaattg acaccgccgt cggttacatg ggcggtacga cagaaaatcc tacatacgaa 120 gaggtttgta ccgacaaaac cggccatgcg gaagtcgtac aagtggaata tgacccggaa 180 caagtgagtt atgaggaact gctgaatgtt ttttgggaca atcataaccc gacgacgtta 240 aaccgccaag gccccgatgt gggaaccaat atcgctcggt tattttttac cacactgaag 300 agcaaagaaa ttccgcagaa aaatccaaag cggaaatgga tcaaagcggg cgttggaaaa 360 atccgattgt gacggagatt gtcccggcca gcactttttg gcgggcggag gagtaccacc 420 aacgttacct gcaaaaacgc gggcttgggt cctgccattt gtaagggaag ggcgctgttc 480 aaataagaac ggcgcctttt tttggatgag ccaatcatgc gtcatctcat tggatggaca 540 agggtcgtga tggttcgaga gggcgtatcc agcagcgttt tcccctatgc tccacctcga 600 tcggcgtatc aaaaaagtca ctaaggagtt cctcggtcaa aacatgggaa gtggggcctg 660 cccgaaaaat ctctccttgt ttgagaagca acgtatgggt aaagcaattt gtaatctctt 720 ccacatggtg cgtgacatag atcagggcag gggattgggg gtgcgcgcta atggattgaa 780 tggaatgaag caattgttca cgggcaaaca ggtcaagccc ggtacagggt tcatccaata 840 tcataagctg gggggaggcc attaatgccc tggcaatcag cactttttgc ttttcccctt 900 gggaaagggt ttgataggtt tgggtaataa gatggccgca ccccatcatt tccagcaggg 960 cagccgcttt ttccatgtca attttttccg gtttgtcgta gaggccgatc gaagcgaatt 1020 ttccgctgag aacgatgttg atggcagttt cgtggttgtg aagttgttgt gccagggatg 1080 aactgaccca gccgatcttt ttgcgaagtt cgcgcaaatt gacttcgcca aactttttcc 1140 cgaataattt gacggttccg gttgtcggcc aaatataacc gtttaccaaa ttcaagagcg 1200 tggttttgcc tgaaccgttt aacccgatca ggcaccagtt ttcaccgggc tgcacttgcc 1260 aggagatatt tttcaaaatc attttccctt cgcgcatcca ggaaacgcta ttcatttcga 1320 taatcatacc ggggctcctt tatctagagt atctatgatt cttttcatta tactgcaaac 1380 ggcaaacgat tgaaggatca tggaaaacgg tttccttagc aaaggggggg aagacaaaat 1440 aaaaatggct tgatcacaga tgcattcaag tgtaaaatga agccgtgaaa ccgttttctt 1500 ggattttatt tttttcgcat tttatgcaaa cgattgcgca aagagggggt tgcaacatga 1560 gaaaattctt atcactggca ctaattagtg cccttgtcat cggtctgttg acggcttgcg 1620 ggccaaagcg ggatccctat gccaaagcgg ggaaaagtga aggaaagcca gacaaattgg 1680 tggtttggga aaatgctgat gatggtgtgc aattgaacaa tacgaaaaag tgggcgggag 1740 agttcacgaa aaagactggc atccaagtgg aagtggtacc ggttgctctt ttaaaacaac 1800 aagaaaaatt gacgctggat ggaccggcgg gcaaaggagc cgatctggta acttggcccc 1860 atgaccggtt gggtgaagca gttaccaagg gattgctgca gccgatccaa gtggataatt 1920 cggtaaaaaa ccaatttgat gatgtggcca tgaaagcttt gacctatggc gggaaactgt 1980 atggtttgcc caaggcgatc gaaagtgtgg cgctgattta caacaaaaaa ttgatgggcc 2040 aagtgccggc cacttatgat gaattgttcc aatatgcgaa agcgaacaac aagccggatg 2100 aacaaaaata tggtgtcctg tttgaagcga acaacttcta ttacacctat ttcctgtttg 2160 cggccaaagg cgctgcggtt ttcaaagaac aggatggtac cttggatcca aacgagatcg 2220 gcctaaacag ccctgaagca gttcaaggaa tgaacgaagt gcagaaatgg tttacggaag 2280 cccgtcttcc gcaaagtttg aaagccgaca cagttaacgg cctgttcaag tctggtaaag 2340 tggcggccgt aatcaatggg ccgtgggcga tcaaagacta ccaagctgcc gggatcaatg 2400 tgggggttgc tccgcttccg aaaatcgatg gaaaggatgc gcaaaccttt atcggggtga 2460 agggatggta tttgtcggct tacagcaaat atccaaaata tgcgaccgaa ttgatgcaat 2520 ttttgacgag taaagaagcg ctcgcttcac gctttaagga aacgggcgaa attccgccgc 2580 aaaaagagtt gctaaacgat ccgatgatca aaaataaccc ggttgtcaat gggtttgcca 2640 agcaagcaag caagggggtt ccaatgccga gcattccgga gatgggagtc gtatgggaac 2700 cgatcaacaa tgcccatacg tttgtggcgc aaggaaagca aacacccgaa caggctctga 2760 atgatgcggt gaagatcatg aaagaaaaaa tccaaacgat gaaacagtaa tggttcggct 2820 cgtgtatttc tgataaatcg gaatttgata aatcatttag gaacggaagg tgcggtggtc 2880 ggcatcgcgc ctttttcgca aaaaaataga agaaggggga gagcgcggtg gagaaagatg 2940 agcggcttca gcaaagcaag cgaaaaatcg cggcggtttt atcggcgctg tcaatggggc 3000 ttgggcaaat gtacaacggg cagtgggtta aaggggtttt atttctggta tgcaggttat 3060 cctatctctt ggtgttttat gatttattca atctcggctt gtgggggatc gtcacgttgg 3120 gaacaattcc cggggtggac aattccatgg agctgttggc ggaagggttg atttctcttt 3180 tattgatttt gttcgggctg tttttttatg ggttgaacat tcgcgatgcg tataaagtgg 3240 gagcgatgag ggagcgcggc attcgcccgc ccggggtgat ggaaacctgc cgccatgtca 3300 ctgaccgggg ctttccctat tttgtgatgg cgccgtcgat gattctgttg atgtttattg 3360 tattgtttcc cattttgttc atggtgacca tcgcattcac caattttgat ttataccacc 3420 aaccgccggc caaattggta agctatgtcg gagtggacaa tttcattaac ctgtttcggc 3480 tgagtttttg gaaaaactct tttttgggcg tgctttcgtg gactgttgta tggacacttg 3540 tttctaccac ggtgcaggtg gcgctgggct tgtttttggc cgttctcctc aaccaaaagc 3600 ggctcaggat caaaaaattt ttccggacgg tattaatttt gccttgggca gtgccatctt 3660 ttgtaaccat tctcgttttc tccggactgt ttgatgataa tttcggcccg gtcaatcatt 3720 ttttggttgc cctcggatta aaggcgatcc cgtggatgtc cgatccattt tggtgcaaag 3780 tggctgtctt gctaattcag ttttggctcg gatttccatt tagcttggcc ttgtataccg 3840 gcgttctgca gtcgatctca agggatcttt atgaagcggc tgaggtggac ggggctaccg 3900 tttggcagaa gttccgccat attaccttac ccatggccct ttattccacc gccccgttgc 3960 tgattgtcca atatgccgga aattttaata attttaatgt gatttatcta tttaataaag 4020 gattgccggc ggtccccgga caaacggcgg gcggaacgga cattttgatt tcttgggtat 4080 acaaactgac ctttgaaacg tccaagtaca attatgcggc cgccatttcg attatgatcg 4140 gtttgattgt ggcggtgctg gcggtttggc agttccgcaa cacccgttcg tttaaagagg 4200 agggaatgat ccagtgagta gcaaaaaatg gagatcccat gtgggtctca ccctcagtta 4260 tctggtgttg attgggatgg cggtgctctc tgtctatccc gtgctatggg tgattggagc 4320 ttcctttagc ccgggggaca ccattttttc cacttcgctg attcccaagc atgcgacgct 4380 ggatcactac aaatggctct tcttcaatcc agatagccaa tacccgactt ggtacctgaa 4440 cacgctgaaa attgctttga tcaatggtgt ggtttccgtc ctcatcacga ccggcacggc 4500 ttatgtattt tcgcggtacc gttttgccgg gcgccagtac gggttgatgt cctttttgat 4560 cctgcagatg tttccttcga cgatgacgat ggtagccatt taccttttgc ttaatatgtt 4620 gcatttgctt gatacgcatc tggggctttt gcttttttat gccggaacgc aaattccttt 4680 taacacttgg cttgtgaaag ggtattttga cacgattccc cacagtttgg atgaagcggc 4740 gcggatcgat ggagcggggc atctaaccat cttctggaaa gtgatattgc cgctggcaaa 4800 acccattttg gcagtcgttt tcctctttaa tttcatgggt cccatgacgg actttctgct 4860 gccgcaaatt atattgacca gcccggaaca ccaaacactg gcggtagggc tcttcagttt 4920 tatcaatgat gatttcaaaa agcagtatac cctgtttgcg gcggggtcgg tgttgattgc 4980 attgccaatt accgttattt tcctgtctct gcaacgctgc tttatttccg ggctcaccgc 5040 gggtgccagc aagggataac gttgaagggg gaagagtcca tgctgttgga agcgattttt 5100 catgaagcga aaggaagcta tgcttacccg atttcggaaa cgcaactgcg ggtgagattg 5160 cgggcgaaaa aaggggacgt ggtgagatgc gaggtgctct atgcggaccg ctatgcttcg 5220 ccggaggaag aactggcaca tgcacttgcg ggcaaagcag ggtccgatga gcgatttgat 5280 tattttgagg ctttactgga atgttccacc aaacgggtga aatacgtgtt tttgttgaca 5340 ggcccacaag gggaggctgt ttattttggc gagaccggtt tttccgccga acggtctaaa 5400 gcgggggtgt tccaatatgc ttacatccac cggagcgaag tgtttacgac accggaatgg 5460 gcaaaggagg cggtgatcta ccagatcttt cccgaacgtt ttgccaatgg ggatcccagc 5520 aatgatccgc cgggaacgga acaatgggcc aaagacgcca gacctcggca cgacagtttt 5580 tacggcggag atttaaaggg ggtgatcgac cgtttgccat atttggagga gttgggagtg 5640 acggcgcttt attttactcc catttttgct tcgccgtccc atcacaaata tgatacagct 5700 gattatttgg cgattgatcc gcaatttggg gatttgccca cctttcggcg tttggtggat 5760 gaagctcacc ggcgcgggat caaaatcatt ttggatgccg tgtttaacca tgccggagat 5820 cagttttttg cgtttcggga tgttctgcaa aagggagaac agtcgcgata taaggattgg 5880 tttttcatcg aggattttcc cgtttccaag acgtcaagaa ccaattatga aacctttgcc 5940 gtccaagtgc cggccatgcc caaattgcgg acggaaaatc cggaagtgaa ggaatatttg 6000 tttgatgtcg cgcgattttg gatggagcag gggatcgacg gatggagact ggatgtggcc 6060 aatgaggtgg atcacgcctt ttggcgcgag tttcgccgcc ttgtcaaatc cctcaatccc 6120 gacgccttga ttgtcggaga gatttggcat gacgcttccg gctggctgat gggagaccaa 6180 tttgattcgg tgatgaatta tttgtttcgc gagagtgtga tccgtttttt tgccacgggg 6240 gagatccatg ccgaaagatt tgacgccgaa cttacccggg ccaggatgct ttatccggaa 6300 caggcggcac aagggttatg gaacctcctc gactcacacg atacggaacg ttttttgaca 6360 tcgtgtgggg ggaatgaggc gaaattccgc ctggctgttt tgtttcagat gacatacctg 6420 gggacgccgc tgatttatta cggtgatgag atcgggatgg ccggagcgac ggacccggat 6480 tgccggcgcc cgatgatatg ggaggaaaaa gagcagaacc gcggcttgtt tgagttttat 6540 aaggaattga ttcgcttgcg ccatcggctg gcatcgctca ccaggggaaa tgtccggtct 6600 tggcatgccg acaaacaagc caatctttat gcttttgtgc gcacggttca agaccaacat 6660 gtcggtgtgg ttctcaataa tcgtggcgag aagcaaaccg ttttgctaca ggtgccggaa 6720 tcgggcggaa aaacttggct ggattgtttg accggagaag aagtgcatgg caaacaaggg 6780 caactgaagc tgacacttcg cccttaccag ggaatgattc tctggaatgg ccggtagatt 6840 ttcggtgccc aaaccagtga ttgggatatg attccaggct agtttttgga taaaattagg 6900 aggatcaaat ggcaaacaaa cgttatttga ttgatgcagt gatcggaaat gacaagatct 6960 tggccgtttt ggaccggtat ggagaattgc accgcttgtg gtggccgcag aaagattatg 7020 cgcaacatgt gaaccggcta tctgccgggg ttctgatccc aggcaaatca aaaggggtct 7080 ggtggtttca tcagcctgcg gggaaacatg agcaaacata tgttcatgat gctcccattc 7140 taagaacgac tgccacgtgc agggagtggc ctctggaagt tgtgtgcgaa gatgaggtgg 7200 tttccggccg gaatgtattg atgcgccatt atgtgatcac caattgcgga gaagaggaaa 7260 tccccctgca atttgtctcc tatacctctt ttcacatggg ggagatgaaa cgttataata 7320 ccactttgtt tgtggggaaa aaagaagcgt tggttcatta ccggcgggaa tttgccgtgg 7380 ctgtcggaag tgtgttgccc acaacccgct ttgcggccgg ttcaaacaaa gatcatatcg 7440 accaggggct ttttaactgc aacgacattg ctatgcacac cgatggcggg tgtttgtggg 7500 aattggggct ttgcccgccg ggagaaagca agtgcatgac tttatttttc gcctttggca 7560 aaacggtaga aaaagcgctg gaagagttgg aagaggcacg gacgttggga tttgaacgtt 7620 tgcgaagcca gaccctggcc gactgggaag cctattttgg acaagcaaaa ccggtacaaa 7680 caggttgtga ggaaatggat cgcctttacc gccgttccct cgccgttttc cggttgatga 7740 cggatgggga atatggaagc atgatcgccg ggcctgagtt tgacgaagat tttgtccggt 7800 gcggcggata tgcgtattgt tgggggcggg acgctgcgta tattgctacc gcgattgacc 7860 gcgcagggta ccatgacagg gttcgcgctt tttaccgttg ggcgatgcaa acgcaaagca 7920 gggatggttc atggcaacaa cggcattatc ttgatggccg cctggccccg caatgggggt 7980 tgcaaatcga tgaaaccggt tcaatcctgt ggggaatgtg gcaacattat ttgctcacaa 8040 atgatcgggc ttttcttgat gagatatggg aaagtgtaca gaaagccgcg cagtttctca 8100 tcctttttat cgacccggaa accggtttgc ccttgccaag ccgtgatctg tgggaggaga 8160 gggaagggga acacacttat tccgcgtcgg ccgtttgcgg tggactcgat gcggcggcgg 8220 ccgtggcaga taagctgggg gaaaaacggc tggcgcaaaa ctggaaagag gcggcaggag 8280 ccatacgccg tgcggttgaa gagaagtgct gggatccgga gcggcaggtc ttttatcgtg 8340 gcttaaagct catggttccc ccggaagaat gggcccacgc tgaaaaggaa ggaaaacggg 8400 ggatgattca cgttgacgaa aagggcattt cccgtccgat gctatggcag gacccggtca 8460 ttgatatcag tttggtggga atcagtgttc ctttcaattt gattgcgcca gatgatgaac 8520 gaatggtaaa aatggcggaa gccattgaaa cccatctgac cagtccgatc gtggggggca 8580 tcaagcggta tgagaatgat ccgtatgttg gaggcaaccc ttggattctt accaccttgt 8640 ggctggcgca gttatatatc aaacagggca gaataaaaaa ggctctcaac catctgaagt 8700 gggtggtgga tcatcgcacc gatttggatc tgttgccgga gcaggttgac cgtgagacgg 8760 ggaaagcggc ttgggtcgta ccgcttactt ggtcccacgc catgtttgtg ttgaccgtct 8820 tggatttgtt ggagattggg gcaattgggc cgaaaaaaag ttgaacctgg gggatttcat 8880 tggaaaaggc gtgcttgatt caattcaggc acgcctaaaa aatgatgttt ccgttgggag 8940 cccggcaaca taaagagaaa tgaacaagag cccaattcaa catacaaaca caatctcata 9000 ttttttggcg aaaaatatag tataatcaat gatgaaaacg attgcacgac ttggtgaata 9060 aattttaaaa aggggttttc gagaatggcg accatcaaag atgtggcaaa attggcggct 9120 gtttcgccat cgactgtatc gcgtgtcatc gcgggaagca accggatcag cttggaaacc 9180 aaacagcgtg tgcaaaaggc gatggaagaa ttgaactatg ttcccaatgc gattgcgcga 9240 agct 9244 // |
|