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EBI DbfetchID AB030011; SV 1; linear; genomic DNA; STD; PRO; 7100 BP. XX AC AB030011; XX DT 22-JUL-1999 (Rel. 60, Created) DT 14-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Pyrococcus kodakaraensis trp operon genes (trpC, trpD, trpE, trpG, trpF, DE trpB, trpA), complete cds. XX KW alpha subunit of tryptophan synthase; KW anthranilate phosphoribosyltransferase; KW beta subunit of tryptophan synthase; component1 of anthranilate synthase; KW component2 of anthranilate synthase; indole-3-glycerol phosphate synthase; KW phosphoribosyl anthranilate isomerase. XX OS Thermococcus kodakarensis KOD1 OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; OC Thermococcus. XX RN [1] RP 1-7100 RA Imanaka T., Ezaki S., Atomi H.; RT ; RL Submitted (13-JUL-1999) to the EMBL/GenBank/DDBJ databases. RL Tadayuki Imanaka, Kyoto University, Graduate School of Engineering; RL Yoshida-Honmachi, Sakyo-ku, Kyoto, Kyoto 606-8501, Japan RL (E-mail:imanaka@sbchem.kyoto-u.ac.jp, Tel:81-75-753-5568, RL Fax:81-75-753-4703) XX RN [2] RX DOI; 10.1007/s004380051145 RX PUBMED; 10628865. RA Tang X., Ezaki S., Fujiwara S., Takagi M., Atomi H., Imanaka T.; RT "The tryptophan biosynthesis gene cluster trpCDEGFBA from Pyrococcus RT kodakaraensis KOD1 is regulated at the transcriptional level and expressed RT as a single mRNA"; RL Mol. Gen. Genet. 262(4-5):815-821(1999). XX FH Key Location/Qualifiers FH FT source 1..7100 FT /organism="Thermococcus kodakarensis KOD1" FT /strain="KOD1" FT /mol_type="genomic DNA" FT /db_xref="taxon:69014" FT CDS 496..1179 FT /codon_start=1 FT /transl_table=11 FT /gene="trpC" FT /product="indole-3-glycerol phosphate synthase" FT /db_xref="GOA:Q9YGB5" FT /db_xref="HSSP:1A53" FT /db_xref="InterPro:IPR001468" FT /db_xref="UniProtKB/Swiss-Prot:Q9YGB5" FT /protein_id="BAA82545.1" FT /translation="MVFGLSRAIRKAEKNAIIAELKVYSPKYGDLLKGRNPFEILRAYE FT RAGAVGISYITDPKYFRGSFEFLRKLCRETELPVLRKDFIASKEEVERTAEAGASAVLL FT ITRLLKEELPEFVDFAKEHGLDTLVEVHSEEELAIALQTDSTMIGINNRDIGKLELDDG FT NVSLTEKLAPLIPKRYVKVSESGIAGTEDLKRALRHADAALIGTALMKTPDREEFLRKL FT VEVEV" FT CDS 1176..2153 FT /codon_start=1 FT /transl_table=11 FT /gene="trpD" FT /product="anthranilate phosphoribosyltransferase" FT /db_xref="GOA:Q9YGB4" FT /db_xref="HSSP:1KHD" FT /db_xref="InterPro:IPR017459" FT /db_xref="UniProtKB/Swiss-Prot:Q9YGB4" FT /protein_id="BAA82546.1" FT /translation="MSLLAKIVDGKNLSFEEAYELFNELKGSDGVLIGAYLAALQTKGY FT TGEELAGLARAMRDSAVKLDLGKVADTAGTGGDGSSTINVSTASALILSAFTRVAKHGN FT VSITSKSGSANVLEALGLNIRVSPERAREMVESTNFTFIFAPAYHPALRPIMPVRKALG FT IKTVFNVIGPLANPADPAYQVVGVNSPELLEPVAEALEFLGVERALVVHGSGMDEVSPH FT RETLVLEVGNGVERYTLSPEDFGIEPVKPLPCSSPEESAARIKAVLGGSGRREDRDFIL FT VNASAALYASGVAEDFREGLEMAREALGQGMLEKLEEIACLSKS" FT CDS 2135..3436 FT /codon_start=1 FT /transl_table=11 FT /gene="trpE" FT /product="component1 of anthranilate synthase" FT /db_xref="GOA:Q9YGB3" FT /db_xref="HSSP:1K0E" FT /db_xref="InterPro:IPR015890" FT /db_xref="UniProtKB/Swiss-Prot:Q9YGB3" FT /protein_id="BAA82547.1" FT /translation="MPLKKLKPVDPLKLYSALRDFGMPFMLRSAEKDSRKARFTYISAE FT PEFVVEVGEGTEIDGERVSDERNPLRALKGLMGERVEGRRFMGGFVGYVSYDSVHSIIG FT GKIEEPSVFGYYPWTFIYDHSTGALSFFYLREAPFDPEALVERARREESRLEDGGSEVI FT STDAGMEEFVEIVRAGKEYIYSGDVFQVVLSREYRVRTDLDALEIYKRLVELNPSPYTF FT ILEFEKTVVGASPETMGSVEGRTFKINPIAGTAPRGRTGEEDRELEKALLSDEKERAEH FT VMLVDLARNDVRRVSKPGSVRLTRFFDVLKYSHVQHIESEVVGELDEGKNAFDAMEAAF FT PAGTLTGAPKIRAMEIIDELERSRRKVYGGAVGYFSLTGDADMAIAIRMAEIEGRKASV FT RAGAGIVADSVPEKEFFETENKMRAVLKALGVRE" FT CDS 3433..4011 FT /codon_start=1 FT /transl_table=11 FT /gene="trpG" FT /product="component2 of anthranilate synthase" FT /db_xref="GOA:Q9YGB2" FT /db_xref="HSSP:1I1Q" FT /db_xref="InterPro:IPR001317" FT /db_xref="UniProtKB/Swiss-Prot:Q9YGB2" FT /protein_id="BAA82548.1" FT /translation="MIVLVNNRDSFVWNLAEYASLFDRVKVVPNTITVGELRRLDPDGV FT IISPGPGHPLERREVGNSPEIVLEAGVPILGVCLGHQIIATAFGGKVGRVKPRHGKASP FT VKHDGKGVLRGIKNPLTAGRYHSLAVLEVPREFDVSAVSLDDNVVMGIRHRKLPIEGLQ FT FHPESVLTEWERKEGLRIIKNFVEMSRNG" FT CDS 4004..4630 FT /codon_start=1 FT /transl_table=11 FT /gene="trpF" FT /product="phosphoribosyl anthranilate isomerase" FT /db_xref="GOA:Q9YGB1" FT /db_xref="HSSP:1DL3" FT /db_xref="InterPro:IPR001240" FT /db_xref="UniProtKB/Swiss-Prot:Q9YGB1" FT /protein_id="BAA82549.1" FT /translation="MVEFVKICGVKTMDELRLVERYADATGVVVNSRSKRKVPLKTAAE FT LIEMAEIPIYLVSTMKTFPEWANAVEKTGAEYIQVHSDMHPKAVNRLKDEYGVSVMKAF FT MVPRESDDPAEDAERLLELIGQYEVDKILLDTGVGSGRRHDYRVSAIIAKEYPIVLAGG FT LTPENVGEAIRWVKPAGVDVSSGVERNGVKDRVLIEAFMAVVRNG" FT CDS 4623..5792 FT /codon_start=1 FT /transl_table=11 FT /gene="trpB" FT /product="beta subunit of tryptophan synthase" FT /db_xref="GOA:Q9YGB0" FT /db_xref="HSSP:2WSY" FT /db_xref="InterPro:IPR006654" FT /db_xref="UniProtKB/Swiss-Prot:Q9YGB0" FT /protein_id="BAA82550.1" FT /translation="MDDMFFGRFGGQFVPETLIEPLKKLERAYKKFKDDPEFNETLEYY FT LRNWAGRPTPLYYAERLSKKLGGAKIYLKREDLLHGGAHKTNNGIGQALLAKFMGKERL FT IAETGAGQHGVATAMAGALLGMKVDVYMGAEDVERQKMNVFRMGLLGARVIPVESGSRT FT LKDAINEALRDWVATFEYSHYLIGSVVGPYPYPVIVRDFQSVIGREAREQILEAEGTLP FT DAVVACVGGGSNAMGIFYPFVNDRVRLIGVEAGGKGLETGLHAASLNAGELGVFHGMLS FT YFLQNEEGQITPTHSVSAGLDYPGVGPEHAYLKDSGRAEYVTVTDEEALRAFHELSRTE FT GILPALESAHAVAYAMKIAPEMDKDEIIIVNLSGRGDKDLDIVRRVGNV" FT CDS 5785..6540 FT /codon_start=1 FT /transl_table=11 FT /gene="trpA" FT /product="alpha subunit of tryptophan synthase" FT /db_xref="GOA:Q9YGA9" FT /db_xref="HSSP:1GEQ" FT /db_xref="InterPro:IPR002028" FT /db_xref="UniProtKB/Swiss-Prot:Q9YGA9" FT /protein_id="BAA82551.1" FT /translation="MFEKGSLIPYLTAGDPSVEKTLEFLLAVEEFAGLIELGIPFSDPM FT ADGKTIQESHYRALRNGFKLDDTFRILREFRRHSSTPVILMTYYNPVFRTGVKKFLGEA FT KASGADGILVVDLPVSHAGEFLDAAKEEGLKTVFLAAPNTPDERLREIDKASTGFVYLI FT SLYGTTGARDRLPETAFEFVRRARKICNNKLAVGFGVSRREQVEELLKAGADGVVVGSA FT LIELISRSENPVEELRRKVAELSGYSRAL" XX SQ Sequence 7100 BP; 1667 A; 1822 C; 2287 G; 1324 T; 0 other; acgaggacag gctctttgac ttcgagggcc tctggaggct tgaaaagccg ctcgtagatg 60 tcgagctcct ccgggaggcg ggggagaggt tcaagctggg cgttgtgacg gggaggaaca 120 gactggagat ggagcttgca gagaggatca tcggcttcag gtttccgaag gttgtgacga 180 gggaaagcgg tttgaagccc gaccccgagc tcctccgatg cctcgtaggg ggtgaggagg 240 gggtttacat cggcgacacg gcaggggacg agctgttcat cgagaactac aggaaaaaat 300 acggggactt cggctttctg atggtcggaa gggacgtgga aaatgcgaac gaagcgataa 360 aaatgttttt ggaggaggtt aaacgagggc cttaacgccc tctcggtctt tttagctact 420 cccttggaca cctcagcatg tccaaagcct tatatcccaa ctcccccttt tgacaccggt 480 gagttcaaat gggtgatggt ttttggatta agcagggcta ttagaaaagc cgaaaagaac 540 gccataatag ccgagctgaa ggtctattct ccgaagtacg gggatcttct gaagggcagg 600 aacccctttg agatccttag ggcctacgaa agggcaggag cggttggaat ctcttacata 660 accgacccga agtacttcag gggaagcttt gagttcctca ggaaactctg cagggaaacg 720 gaactgccag ttttgcggaa ggacttcata gccagcaagg aggaagtcga aaggactgct 780 gaagcaggag cttcggcggt tctcctgata acgcggcttc tgaaagagga actgcccgag 840 ttcgtggact tcgcgaagga gcacggcttg gacaccctcg tggaggtgca cagcgaggag 900 gagctggcga tagcactcca gacggactca acgatgatag ggataaacaa ccgcgacata 960 gggaagcttg agctcgacga tggcaacgtg agcctaacgg aaaagctggc gccgctcata 1020 ccgaaaagat acgtgaaggt cagcgagagc ggcatagcgg gcacggaaga cctgaagagg 1080 gctttaagac atgcggatgc cgctctgata ggcaccgcgc tcatgaagac cccggatcgt 1140 gaggagtttc tcaggaagct cgtggaggtg gaagtatgag ccttcttgcg aagatcgtcg 1200 atggaaagaa cctgagcttt gaggaggcct acgagctctt caacgagctg aaggggagcg 1260 atggagtgct tataggggcc tacctggctg cactccagac caagggctac accggcgaag 1320 agctcgcggg tctggcgagg gcaatgaggg acagcgcagt caagctcgac ctcgggaagg 1380 tggccgatac agccgggacg gggggagacg gcagctcgac cataaacgtc agcacggcct 1440 cggctttgat actctcggcc ttcacgaggg tcgctaaaca cggaaacgtt tccataacat 1500 cgaagagcgg ctcagccaac gtacttgagg cgcttggctt aaacatacgg gtttccccgg 1560 agagggccag ggagatggtc gaaagcacga acttcacgtt catcttcgct cccgcctatc 1620 acccggcact cagaccaata atgcccgtga gaaaggccct cgggataaag acagtcttca 1680 acgtcatcgg gccgcttgcg aatccagcgg atccagcata ccaggtagtc ggagtcaact 1740 ctccagagct tctggaaccc gtggcagagg ccctggagtt ccttggggtt gagagggccc 1800 tggttgtcca cggttcgggc atggatgagg tgtccccaca cagagagacc ctcgtcctgg 1860 aggttggcaa tggagttgag aggtacacgc tctcacctga ggacttcgga atcgagcctg 1920 tgaagcccct gccgtgctcc tccccggaag agagcgccgc gaggataaag gcggttctag 1980 ggggttcggg aaggcgggag gacagggact tcatcctcgt caacgcttcg gcggctctct 2040 acgcgtcagg ggttgcggag gactttaggg agggccttga gatggccagg gaagccctgg 2100 gccagggaat gcttgaaaaa ctggaggaga tagcatgcct ctcaaaaagc tgaagcccgt 2160 tgaccctttg aagctctaca gcgcccttag agactttggg atgccattca tgctccgctc 2220 tgccgagaag gactccagga aggccagatt cacctacata tcggccgagc cggagttcgt 2280 cgtggaggtc ggcgagggga ctgagatcga cggggagcga gtttccgacg agaggaaccc 2340 cctcagagct cttaaagggc tcatggggga gagggtcgag ggcaggaggt tcatgggtgg 2400 cttcgttggc tacgtctcct acgattcggt acactccatc atcgggggga agatcgaaga 2460 gccctcggtc ttcggctact acccctggac cttcatctac gaccactcta ccggcgctct 2520 ttccttcttt tacctcagag aggctccttt cgaccccgag gccttagttg aaagggccag 2580 gagggaagag tcacggcttg aagacggcgg ttcggaggtc atatccaccg acgcgggcat 2640 ggaagagttc gttgaaatcg tcagggctgg gaaggagtac atctactcgg gggacgtctt 2700 ccaggtggtt ctgtcgcgcg agtacagggt tagaacggat ctcgatgccc tcgaaatcta 2760 caagcggctc gtggagctca acccctcccc gtacaccttc atcctggagt tcgagaagac 2820 cgtcgtaggg gcctcacccg aaaccatggg ttccgtcgag gggagaacct tcaagataaa 2880 ccccatagca ggaacagcgc cgaggggaag gacgggggag gaagaccggg agctggaaaa 2940 ggccctactc tccgacgaga aagagcgagc tgagcacgtc atgctcgttg accttgctag 3000 aaacgacgtc aggagggttt caaagcccgg gagcgttagg ctaacccgct tcttcgacgt 3060 cctgaagtac agccacgtcc agcacataga gagcgaggtg gtcggtgaac tcgatgaggg 3120 gaaaaacgcg ttcgacgcca tggaggcggc ttttccggcg ggaacactaa ccggagcccc 3180 gaagataagg gcgatggaga tcatagacga gctggagagg agcaggagaa aggtctacgg 3240 gggagcagtg ggttacttct ccctcaccgg ggacgccgac atggcgatag cgataaggat 3300 ggccgagatc gagggcagga aagcgagcgt tagggccggg gcaggaatag tggcggattc 3360 agttccagag aaggagttct tcgagaccga gaacaaaatg agagcagttc tgaaggcgct 3420 gggggtgagg gaatgatagt cctcgtcaac aacagggact ccttcgtctg gaatttagcc 3480 gagtacgcct ccctcttcga cagagtgaag gtcgttccga acactataac cgttggggag 3540 ctcagaaggc tcgaccccga tggagtgata atctcccccg gcccggggca cccgctcgag 3600 aggagggaag tgggaaactc gccggagata gtcctcgagg cgggggtacc tatcctcggg 3660 gtctgcctcg gccaccagat aatagcgacg gcattcggcg ggaaggtggg gagggtaaag 3720 cccaggcacg ggaaggccag ccccgtgaag cacgacggga agggcgtttt gaggggaatc 3780 aagaacccgc tgaccgctgg aaggtaccac tccctcgccg ttctggaggt tccaagggag 3840 tttgatgtga gcgccgtttc cctcgacgat aacgtggtca tggggataag gcacaggaag 3900 ctcccgatag agggccttca gttccaccct gaaagcgttc tgaccgaatg ggagaggaaa 3960 gaaggcttga ggatcatcaa aaacttcgtg gagatgagca gaaatggttg agttcgttaa 4020 gatatgcggc gtaaaaacaa tggatgagct caggcttgtc gagaggtacg ccgatgcaac 4080 gggagtggtg gtgaactcaa ggtcgaagag gaaggtgccg ctgaagacgg ccgcggagct 4140 gattgagatg gcagagatcc caatctacct cgtttccacc atgaagacct tcccagagtg 4200 ggccaacgcg gtagagaaga ccggggccga gtacatacag gtgcactcgg acatgcaccc 4260 caaggccgtc aacaggctga aggatgagta cggggtgagc gttatgaagg ccttcatggt 4320 cccaagggag agcgacgacc ccgcggaaga tgcggaaagg ctcctcgagc tcatagggca 4380 gtacgaggtt gacaagatac tcctcgacac aggggtgggg agcgggagga ggcacgacta 4440 cagggtgagc gcgataatag ccaaggagta cccgatagtc ctggccggag gtttgacccc 4500 ggagaacgtt ggggaagcga taaggtgggt taaaccagct ggagtcgacg tttcgagcgg 4560 cgttgagagg aacggcgtca aggacagggt tttgatagag gccttcatgg cggtggtgag 4620 gaatggatga tatgttcttc ggaaggtttg ggggccagtt cgtccccgag acgcttatag 4680 aacctttgaa gaagcttgaa agggcttaca aaaagttcaa ggacgaccct gagttcaacg 4740 aaaccctcga gtactacctg cggaactggg cgggaaggcc gacgcccctc tactacgcgg 4800 agaggcttag caaaaagctg ggaggggcga agatatacct caagagggag gacctcctcc 4860 acggcggggc ccacaagacg aacaacggca tagggcaggc cctcctcgcc aagttcatgg 4920 gcaaggagag gctcatagcc gagaccgggg cgggccagca cggcgtcgcc acggccatgg 4980 cgggggcgct cctcgggatg aaggtagacg tttacatggg cgccgaagac gtcgagaggc 5040 agaagatgaa cgtcttccgc atggggctgc tcggcgcgag ggttattccc gtcgaaagcg 5100 gctcaagaac cctgaaggat gccataaacg aggccctccg cgactgggtt gccaccttcg 5160 agtactccca ctacctaata ggctcggttg tcgggcccta cccatacccg gtcatcgtga 5220 gggacttcca gtcggtaata ggcagggagg ccagggagca gatactcgaa gccgagggga 5280 cgctaccgga tgcggtagtg gcatgtgtcg ggggcgggag caacgcaatg ggcatcttct 5340 accccttcgt gaacgatagg gtcaggctca taggcgtcga agccggggga aagggcctcg 5400 aaacgggcct ccacgcggcc tcgctgaacg ccggcgagct cggcgttttc cacggcatgc 5460 tcagctactt cctccagaac gaggagggcc agataactcc tacccacagc gtttcggcgg 5520 ggctcgacta cccgggagtt ggtcccgagc acgcctacct caaggatagc ggaagggccg 5580 agtacgtcac ggtgaccgac gaggaggctc tgagagcctt ccacgagctt tccaggacgg 5640 agggaatact tccagcgctc gaatcggccc acgcggtagc ctacgcgatg aaaatagccc 5700 cagagatgga taaagacgag ataatcatag tcaacctctc tgggaggggc gacaaggacc 5760 tggatatagt caggagggtc gggaatgttt gagaagggct cgctgattcc ctatctcacg 5820 gccggcgacc cgagtgtcga aaagaccctt gagtttttac tagcggtcga agagttcgcc 5880 ggtctaatag agctcggaat ccccttcagc gacccgatgg cggacgggaa gacgatccag 5940 gagtcccact accgcgccct gaggaacggc ttcaaactcg atgatacctt caggatcctc 6000 cgcgagttca ggaggcactc ctctacccca gtaattctga tgacctacta caacccggtt 6060 ttcaggacgg gcgttaagaa gttcctcgga gaggctaagg ccagcggggc cgacgggatc 6120 ctcgtggttg accttcctgt gagccatgca ggggaattcc tcgatgcggc caaggaagag 6180 gggctaaaga cagtatttct tgcagcccca aacactcccg atgaaaggct tagggagata 6240 gataaagcct ctaccggctt cgtctacctt atctccctgt acgggaccac tggagcccgc 6300 gacagacttc ccgagacggc tttcgagttc gtgaggcgcg ccagaaagat atgcaacaac 6360 aagctggcag tcggcttcgg tgtttcgagg agggagcagg tggaggagct tttgaaggct 6420 ggagccgacg gggttgtcgt tggaagcgcg cttatagagc taatatcccg cagtgagaac 6480 cccgtggagg agctgaggag aaaggtggcg gagctctcgg gctactccag agctctgtag 6540 aacctttcgt aggcctcttc tatttcttcc cattccagtt tttccctgag tctctccggg 6600 tccggcgggt ttttcctcat gaagtctagg aactcctcta tctgctccct ggacatgctg 6660 aggacttccc ttatgaaatc gggagaatcg tggagcaccg cctttccgta ggtctccagg 6720 aaggcccagg aggttccgcc aaactcctcc agtccgagct ccctggagag cgagaggtag 6780 cttaatccga tgaagtaggg gacgcctatg acgaagccca tgagcctgtc gtgggtcttc 6840 cagtcgagga aggacacgtt ccccccgatg gagcgtataa agtcggcgac ttcctccgca 6900 tccttctccc ttcctggaat ggggaccgtt atgaacctct tcccctcgat ggtcttcgcc 6960 ccgggcccga acatcgggtg aacgctcgca actcttgttt cctcgccaaa gcccgcgtag 7020 gcttcaacaa cgcgggactt gaaagtggct atgtcgaaga cgatcttttt cccgccgtgc 7080 tccctcgata tttccgcgag 7100 // |
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