 |
|
EBI DbfetchID AACQ01000293; SV 1; linear; genomic DNA; WGS; FUN; 12935 BP. XX AC AACQ01000293; AACQ01000000; AACQ00000000; XX DT 04-MAY-2004 (Rel. 79, Created) DT 04-DEC-2008 (Rel. 98, Last updated, Version 4) XX DE Candida albicans SC5314 chromosome R Ctg19-20083, whole genome shotgun DE sequence. XX KW WGS. XX OS Candida albicans SC5314 OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; mitosporic Saccharomycetales; Candida. XX RN [1] RP 1-12935 RX DOI; 10.1073/pnas.0401648101 RX PUBMED; 15123810. RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., RA Scherer S.; RT "The diploid genome sequence of Candida albicans"; RL Proc. Natl. Acad. Sci. U.S.A. 101(19):7329-7334(2004). XX RN [2] RP 1-12935 RA Dungan J., Kuo A., Newport G., Lan C.-Y., Iijima C., Adegbola O., RA Roberts J., Persson K., Donnelly S., Favoreto S., Tzung K.-W., Jones T., RA Scherer S., Agabian N.; RT "Annotation of the Genome of Candida albicans"; RL Unpublished. XX RN [3] RP 1-12935 RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., RA Scherer S.; RT ; RL Submitted (16-APR-2004) to the EMBL/GenBank/DDBJ databases. RL Stanford Genome Technology Center, 855 California Avenue, Palo Alto, CA RL 94304, USA XX CC We developed computational methods to reconstruct the diploid CC genome sequence, using phrap contigs as a starting point. The CC genome sequence obtained by these methods is much less fragmented CC than the original phrap assembly, and is in good agreement with CC available physical mapping data. It differs in various respects CC from other genome sequences in that both copies of the genome are CC explicitly represented. CC Many of the contigs occur in homologous pairs. The DNA sequence of CC paired homologous contigs is usually similar throughout, although CC in certain regions, such as the mating-type locus, divergence CC between the homologs is considerable. Paired homologous contigs CC have numbers differing by 10000; for example, contigs 10065 and CC 20065 form a homologous pair. In addition, some contigs do not CC have homologous partners. Such contigs appear to contain either CC homozygous sequence, or in a few cases, repeat sequences that occur CC in multiple locations in the genome. All contigs with numbers less CC than 10000 are unpaired. In addition, contig 10262 is unpaired. XX FH Key Location/Qualifiers FH FT source 1..12935 FT /organism="Candida albicans SC5314" FT /chromosome="R" FT /strain="SC5314" FT /mol_type="genomic DNA" FT /db_xref="taxon:237561" FT gene complement(<1..379) FT /locus_tag="CaO19.8621" FT mRNA complement(<1..379) FT /locus_tag="CaO19.8621" FT /product="non-LTR retrotransposon Zorro 3 orf1-related FT protein" FT CDS complement(<1..379) FT /codon_start=1 FT /transl_table=12 FT /locus_tag="CaO19.8621" FT /product="non-LTR retrotransposon Zorro 3 orf1-related FT protein" FT /note="closely related to N termini of non-LTR FT retrotransposon Zorro 3 orf1 and CaP19.562; allele of FT CaO19.1006" FT /db_xref="UniProtKB/TrEMBL:Q59KK1" FT /protein_id="EAK90999.1" FT /translation="MTTNGTNGFDFADKGDHPPRQSQENPPGNFQESPLDGGQIRKSSS FT NDGVSNNVEFNTNTNAHESWADYPESDQMDTDSSEYYTEDENEEGKIPKGPYHQFQNAN FT KFTYFKQKIAKTLVPPKKITQN" FT variation 933 FT /replace="a" FT variation 981..982 FT /replace="" FT gene complement(1072..2130) FT /gene="KCS1" FT /locus_tag="CaO19.8622" FT mRNA complement(1072..2130) FT /gene="KCS1" FT /locus_tag="CaO19.8622" FT /product="hypothetical protein" FT CDS complement(1072..2130) FT /codon_start=1 FT /transl_table=12 FT /gene="KCS1" FT /locus_tag="CaO19.8622" FT /product="hypothetical protein" FT /note="similar to InositolP6 kinase; allele of CaO19.1007" FT /db_xref="GOA:Q59KK0" FT /db_xref="InterPro:IPR005522" FT /db_xref="UniProtKB/TrEMBL:Q59KK0" FT /protein_id="EAK91000.1" FT /translation="MVLIVVDVLRKKNFDTGVVMNNITTSQMQPFKNKVGGHTPIFSIS FT KQEICKELNNTERNFYKKISKNHPLFYYMPRYKGSNGSQIILEDLTSQMRTPCILDLKM FT GTRQYGCNATITKQQSHRAKARSTTTRKLGVRICGLQIFNYQNKYFYQDKYLGRKITVG FT KQFGKILAKFLYNGHDIYSLLNRIPHLIDQLKELYTIFTGLPGYRMYGSSILLMYEGGE FT DNSENQVKVKIIDFANAVIAGEENIDNVTVPPQHPDSPDLGYLRGLNSLIVYFTLIFSI FT LSRIKLNNTKEMVDWIQENKQTLKEQSCPWLDDYAELDGLKDGSIHQDMCDDPFDIEYP FT EYTPEEDEGLSE" FT variation 1246 FT /replace="a" FT variation 1840 FT /replace="a" FT misc_feature 2108..3255 FT /note="heterozygous homologous region at bases 2108..3270 FT of Ctg19-10083 version 1" FT gene 2714..3049 FT /locus_tag="CaO19.8623" FT mRNA 2714..3049 FT /locus_tag="CaO19.8623" FT /product="hypothetical protein" FT CDS 2714..3049 FT /codon_start=1 FT /transl_table=12 FT /locus_tag="CaO19.8623" FT /product="hypothetical protein" FT /note="no clear allele" FT /db_xref="UniProtKB/TrEMBL:Q59KJ9" FT /protein_id="EAK91001.1" FT /translation="MGEERLLLLLSVFRFRVVVWKLQNVVFIAIPKTLHPATAITTRIH FT HPRGIPSNNKPKKQEQRNTTSSYLAHAPLLLLFLFSLFLSTCLCFLSTNSFTYHIPFWN FT PCQKVKL" FT variation 3275 FT /replace="a" FT variation 3469 FT /replace="g" FT variation 3470 FT /replace="t" FT variation 3475 FT /replace="a" FT variation 3480 FT /replace="c" FT variation 3499 FT /replace="a" FT variation 3661 FT /replace="a" FT variation 3662 FT /replace="c" FT gene 3773..4909 FT /gene="MNT3" FT /locus_tag="CaO19.8624" FT mRNA 3773..4909 FT /gene="MNT3" FT /locus_tag="CaO19.8624" FT /product="hypothetical protein" FT CDS 3773..4909 FT /codon_start=1 FT /transl_table=12 FT /gene="MNT3" FT /locus_tag="CaO19.8624" FT /product="hypothetical protein" FT /note="mannosyltransferase similar to S. cerevisiae KTR1p; FT allele of CaO19.1010" FT /db_xref="GOA:P87207" FT /db_xref="InterPro:IPR002685" FT /db_xref="UniProtKB/Swiss-Prot:P87207" FT /protein_id="EAK91002.1" FT /translation="MLRHLVFILIAILLLTFPPKIESLFKSFIINKPTKTTCYQYTTRE FT QLKSILESDIHETNFCIEKPSTSPPKTNSTLLMLCQNSDIFSVLETIQNIQDRFNDKYN FT YDYTFLNDVPFNYEFIYLVSSIIPHGKINFGLIPIEHWSYPSHINISLATEIRQNYANV FT PYGDSESYRHMCRFYSGFFYKHELVKQYQYYWRIEPGIKIYCDIDYDVFEYMIINDKKY FT GFVISLFEYSETIPTLWNHVVQYINDNEIKSELLPLLTNKYNWYNLCHFWSNFEIANLD FT IFNNDDYENFFQYLDNLGGFYYERWGDAPIHSIAIALFLQKKDIHWFENIGYYHVPYLQ FT CPQDIDLYVKNKCTCNPDEDFTWSDLSCTNHFLNILHN" FT variation 3779 FT /gene="MNT3" FT /locus_tag="CaO19.8624" FT /replace="t" FT misc_feature 3881..4493 FT /gene="MNT3" FT /locus_tag="CaO19.8624" FT /note="heterozygous homologous region at bases 3896..4508 FT of Ctg19-10083 version 1" FT gene complement(4984..6966) FT /gene="MNN21" FT /locus_tag="CaO19.8625" FT mRNA complement(4984..6966) FT /gene="MNN21" FT /locus_tag="CaO19.8625" FT /product="hypothetical protein" FT CDS complement(4984..6966) FT /codon_start=1 FT /transl_table=12 FT /gene="MNN21" FT /locus_tag="CaO19.8625" FT /product="hypothetical protein" FT /note="possible mannosyltransferase; one of six C. albicans FT genes similar to S. cerevisiae Golgi mannosyltransferase FT MNN2 (YBR015C); allele of CaO19.1011" FT /db_xref="UniProtKB/TrEMBL:Q59KJ7" FT /protein_id="EAK91003.1" FT /translation="MFQQLTYRLRLFRRRHKYIFINSIFLSVIIIFLIYSYWSNLPAED FT NSAIINEKGTYHRSLWESITMALFPPKTKPFEEKKPQVNPNNNQEVGVESGASEISQHK FT QQQQQQQHAKEPTTKTSSKSLVSDEAYQLNLKLINEQQEKYNRLHPFEQKRLQQGYEFF FT DNIFKIFYQAKPSVSQLNTYPSKKRIYHARFDSLADDDTIFSEKYLSQFLQLSNEELAA FT MKKSHKYVVENLPEDAPDGLYKKNGIVYVAGGSFNWLTLLSIKSLRAVGCHLPIEVFIP FT KIEEYESDLCNRILPELDARCIYMKNQLMNPNKDNSDSFANKFEFKGYQYKALAILLSS FT FENVLLLDSDNIPAHSPEELFENDPFKSYGLVVWPDYWKRATSPYYYNIADIDVSEKYL FT GSKYNEVEGQYTDLSVEKGSVELDKIPLHQRLGSIPDPTSESGQLLISKKTHLKPLLLA FT LYYNLYGPSHYYPLFSQGSDGEGDKETFLAATVTLGKRYYQVAKFLVSLGHFKVPGGDF FT EGCGMGQFDPQQDLEYIKLREQYAKIPEKDKEKQHKFKLQHQVLEKGPEILFVHANFPK FT LNPWKLKQEKKIFDAKGNRVRLYGPGMIKRIGYDFEWFQWEGMKYLLCIYDVNLQIFQD FT VKKSDLCDEILEHLRFLESTQNITD" FT variation 7696 FT /replace="t" FT variation 7750 FT /replace="t" FT variation 7859 FT /replace="t" FT gene 8257..8718 FT /gene="APS1" FT /locus_tag="CaO19.8626" FT mRNA 8257..8718 FT /gene="APS1" FT /locus_tag="CaO19.8626" FT /product="potential clathrin-associated protein AP-1 FT complex component" FT CDS 8257..8718 FT /codon_start=1 FT /transl_table=12 FT /gene="APS1" FT /locus_tag="CaO19.8626" FT /product="potential clathrin-associated protein AP-1 FT complex component" FT /note="similar to S. cerevisiae APS1 (YLR170C) small FT subunit of the clathrin-associated protein AP-1 complex; FT allele of CaO19.1012" FT /db_xref="GOA:Q59KJ6" FT /db_xref="InterPro:IPR016635" FT /db_xref="UniProtKB/TrEMBL:Q59KJ6" FT /protein_id="EAK91004.1" FT /translation="MAIQFLFLISRQGKTRLSKWYQTISQKEKSKIIRELSTIILSRRA FT KMCNVLEYKDLKIIYRRYASLFFVIGVNSDDNELIGLEIIHRFVEQMDKIYGNVCELDI FT IFGFDKAYHILDELLIDGYLQESSKREVLKRVNQQDELENMDEFENILA" FT variation 9380 FT /replace="g" FT variation 9461 FT /replace="t" FT variation 9582 FT /replace="c" FT gene complement(11720..12031) FT /locus_tag="CaO19.8627" FT mRNA complement(11720..12031) FT /locus_tag="CaO19.8627" FT /product="hypothetical protein" FT CDS complement(11720..12031) FT /codon_start=1 FT /transl_table=12 FT /locus_tag="CaO19.8627" FT /product="hypothetical protein" FT /note="allele of CaO19.1013" FT /db_xref="UniProtKB/TrEMBL:Q59KJ5" FT /protein_id="EAK91005.1" FT /translation="MSGDFFFKLLSIFKKHVLFNYEGFFFSKNVVQVVPAGFFFRVNKF FT FFCFQCFLCNLCGIKYLGKTPPTIVTIHTTLAHTNIRQKKREQESNKVKQKSISSNKF" XX SQ Sequence 12935 BP; 4296 A; 2077 C; 2080 G; 4482 T; 0 other; tgttttgtgt aattttttta gggggaacca aagtttttgc aattttttgt ttaaaataag 60 taaatttatt agcattttga aattgatggt atggaccttt ggggatcttt ccttcttcgt 120 tttcatcttc tgtatagtat tcagatgaat cagtatccat ctggtctgat tcagggtagt 180 cagcccacga ctcgtgcgca tttgtatttg tattgaattc gacgttgttg gaaacaccat 240 cgttcgacga tgatttccga atttgaccac catctaacgg cagctcttga aaattcccag 300 ggggattctc ttgagactgc cgaggcggat gatcaccttt atcagcaaaa tcaaaaccat 360 tagtaccgtt cgtagtcata ataatttttt tttttttttt tttttttttt tttttttttc 420 cccaaaaatt ttggggaagg aaggtgggga acaagtcacc aagaggtcaa cagggaaaaa 480 aatttaattt tccattcatg gcaaaatcaa attttttttt tgggcccccc tttttcttag 540 taataatgat attgtgttct gttgcttagt tgttcagtgt gtcaaagtat cgaattctcc 600 ccaatcaaaa atcgttctcg gtccaaaaaa atttcaattc catccgaata gaaccaaaaa 660 aaaatagaat aaaataaatt gatttgcatt cttgaaaatt tttcttttca atacaaaaca 720 ggcaccacaa actaaagaga aaaaaaaaaa gaaattaaca tagtttagca acttgtttgc 780 taccatatga tcattatata catttattaa ccaaccaacc aaccaccaat ggtctgaaac 840 ctcactagaa ggggagagaa aaataacgtc aatcctttat ttacacatgg gtccatcagg 900 gccgcgcaat atctacgtcc aaatatattt ttggaattta tttgtttgta ttaaaattaa 960 tctctaaaat gcacatctat acacacacac acatacacac agagtatttc tctgactcgt 1020 ttatttactt ctctcactca ctcactaata attaaaactt gtagaacctt gttactctga 1080 aagtccttcg tcttcttctg gggtatattc cggatattcg atatcaaaag gatcgtcaca 1140 catatcctga tgaatactac cgtctttcaa gccgtccaat tcggcataat catccaacca 1200 gggacacgat tgttctttta aagtttgctt gttttcttga atccagtcaa ccatttcttt 1260 ggtgttgttt agttttatcc ggctaagaat actaaaaatt aatgtaaaat aaacaattaa 1320 cgaatttaac cctcgtaaat aacccaagtc tggtgaatca gggtgttgtg gtggcacagt 1380 aacattatct atattttctt cgcctgctat tactgcatta gcaaaatcta taattttcac 1440 ttttacttga ttttccagat tatcttcacc tccttcatac attaataata tcagactacc 1500 atacattcta taccctggta atccagtaaa tattgtgtat aattctttaa gttgatcgat 1560 taaatggggg atacggttta ataatgaata aatgtcatgg ccattatata aaaattttgc 1620 taaaattttg ccaaactgtt taccaacagt tatttttctt ccaagatatt tatcctgata 1680 gaaatatttg ttttgataat taaagatttg aagtccgcat attctaacac ccaattttct 1740 tgttgttgtg cttctggctt tagctcgatg tgattgttgt ttggtgatag ttgcattaca 1800 cccatattgt cttgtcccca tctttaaatc caatatacag ggagttctca tttgagatgt 1860 aagatcctct agaattattt gggatccatt actaccttta taccttggca tataataaaa 1920 taaaggatga ttcttggaga ttttcttgta gaaatttcgt tcggtattgt tgagctcttt 1980 gcatatttct tgctttgata ttgagaatat gggtgtatga cctcccactt tgtttttaaa 2040 cggctgcatt tgggaagtgg taatattatt catgacaaca cctgtatcaa agtttttttt 2100 cctaagtaca tcaactacaa ttaacaccat cgtaagaaat cgtgcaaatg tgactaaaaa 2160 aaatagatgg aaatatctcc cacaagtttt cccaaaaaaa acacaaactt aaatggattt 2220 ctcttttttg attttgttac gggacccgcc cctcgaaata tatattctat tttatgttac 2280 acacttaaag atgggatgat aaagggatgg taggaaaaca aaatgataaa attaaatagg 2340 aagtagttca cttcagggga agtttttttt cgaattgaaa aaaaatataa ttattaggat 2400 acacagagag ttttatatct ttacattctt aaagttgaaa cgcagtttat gatgataaat 2460 aacacacagt gtgatatgta tcaacaacaa aaaaaggttt gtgaaaaaag aaaaagccac 2520 aaaaaagtta ctatcttaaa acaaaacaaa ctaatcccaa agttaatgaa gattttcttc 2580 agttttgaaa aaaaaaaaga aacaagaaat ctaaggaaca tgtgggtcat cttttggcca 2640 gctcatctaa tcattcaaaa ttccgatacc gtgtctatag tataaagagg atgtgtgact 2700 attttttttt ttgatggggg aagaaagatt attgttgttg ttgctggtgt ttcggtttag 2760 agttgttgta tggaaattgc aaaacgtggt gttcatcgcg attccaaaaa ctttgcaccc 2820 cgccaccgcc atcaccacca gaattcatca tccacgcggt atacccagca acaataaacc 2880 aaaaaaacag gaacagagaa atacgacatc atcttatctt gcccacgccc ccctcctcct 2940 cctcttcttg ttttctcttt tcttatctac ttgcttatgc tttttatcaa caaactcttt 3000 cacgtaccac attccctttt ggaatccttg ccaaaaagtc aaactttaaa acttagacga 3060 aaaaaatttg cttttgttaa atatcattat ttttgttttt ttttgatagt gggaaatgaa 3120 atgaaaccta aaactggaag tttaagtatt gtattttagc agcatagatc aatgattgtt 3180 taacaataag attattgacg tatccctcct acataattat ctacataacc aagattcaaa 3240 agaaaatgca gcagttgcaa attcaactta gttcgaacat ttatatcttg catttgtttt 3300 tattattctc ttctaagcac tagtggcaaa gtagttttta tttttgttat gatctataac 3360 actgtgggta tgtatttgta aaactattac gaaatgtatg gatttcattt atgcaatacg 3420 tggtgtaatt tttcatgtcg gtattaataa atccaaaaaa aacaaaaaaa ataagcaccg 3480 ttttgatgtt gatcaatagc taacagtgta aacaccaaga ggtacccaag tacatgcacg 3540 tgtatgctgt atacttcaat taacattaat tttgatttgc tttttttttg caactagatt 3600 caataaaaat ttcataacaa ttgttgtgaa tacgtagagg aaaaaaagaa acgaaacaaa 3660 gttgtgttca aagtctgaaa aatcttcagc caaaaaaata aataaaaccg tccattcaaa 3720 ccattacaag aatgataaat atctgacttg attacagatt ctttacttaa taatgctacg 3780 gcatttggta tttattttga ttgcaatact tttattgaca ttccctccta aaatcgaatc 3840 tttattcaaa tcttttatca tcaataaacc aactaaaaca acatgttatc aatataccac 3900 tcgtgaacaa cttaaatcaa tacttgaatc agatatccat gagacaaatt tttgtattga 3960 aaaaccttcc acatcacccc caaaaacaaa ttctacattg ttaatgttat gtcaaaattc 4020 cgatatattt tccgtattag aaaccattca aaacattcag gatcgattca atgataaata 4080 caattatgat tacacgtttt taaatgacgt tcccttcaac tatgagttta tttatttagt 4140 atcatcaatt atccctcatg ggaaaatcaa ttttggtctt ataccaattg aacattggtc 4200 atatccatca catataaata tatcattagc tactgaaatc agacaaaatt atgctaatgt 4260 cccttatgga gattcagaaa gttatcgaca catgtgtcga ttttattctg ggttttttta 4320 taaacatgaa ttggtcaaac aatatcaata ttattggaga atagaacctg gcattaaaat 4380 atattgtgat attgattatg atgtgtttga atatatgata attaatgata aaaaatatgg 4440 atttgtgatt tcattatttg aatactcgga aactattcct acgttatgga atcatgttgt 4500 tcaatatata aatgataatg aaatcaaatc agaattgtta ccacttttga ctaataaata 4560 taattggtat aatttatgcc atttttggtc gaattttgaa attgcaaatc ttgatatatt 4620 taataatgat gattatgaaa attttttcca atatttggac aatttaggag ggttttatta 4680 tgaacgatgg ggtgatgctc caatacattc cattgctata gcattgttct tacaaaaaaa 4740 ggatattcat tggtttgaaa atataggcta ctatcatgtt ccatatctac aatgtcctca 4800 agatattgac ttgtacgtca agaataagtg tacttgtaac cccgatgaag attttacatg 4860 gagtgacctt agttgtacta accatttctt gaacattcta cataattgaa aaaaatactt 4920 gtaatgtgtt ttttttttct gtattgctat tgtattttgt cttggtgtat attgtgatgt 4980 attttaatca gttatattct gtgtactttc caaaaatctt aaatgctcca aaatctcatc 5040 acataaatct gattttttaa catcctgaaa aatttgtagg ttaacatcat aaatacatag 5100 taaatatttc attccttccc attgaaacca ttcaaaatca tacccaattc tttttatcat 5160 acctggtcca tataatctaa ctctattgcc tttagcatca aatattttct tctcttgttt 5220 taacttccat ggattcaatt tagggaaatt agcatggaca aataaaatct ctggcccctt 5280 ttccaaaact tgatgttgta atttgaattt atgttgtttt tctttatcct tttctggtat 5340 tttggcatat tgttctcgta acttgatata ttccaaatcc tgttgaggat caaattgtcc 5400 cattccacat ccttcgaaat caccaccagg cactttgaaa tggcctaaag acaccaaaaa 5460 tttggcaact tggtaatacc ttttgcctaa cgtgactgta gcagccaaaa atgtctcttt 5520 gtcaccttca ccatctgatc cttgtgaaaa taatggataa taatgtgatg gcccatataa 5580 attgtaatat aaagctaata ataatggctt caaatgagtc tttttcgaaa tcaataattg 5640 acctgattca ctagtaggat caggtatgct tcctaaccgt tgatgtaatg gtattttatc 5700 taattcaact gatcctttct caactgataa atcagtgtat tgtccttcca cttcattgta 5760 cttactaccc aaatattttt cgctgacatc aatgtcagca atgttgtagt aatatggaga 5820 tgtggcacgt ttccaatagt ctggccagac caccaaccca taagatttaa atgggtcatt 5880 ttcaaatagc tcttctggtg aatgtgcagg gatattatca ctatcaagca acaacacatt 5940 ctcaaaactg gataataata tcgccaatgc tttatattga taacctttga attcaaactt 6000 gttagcaaag ctatccagat tatctttgtt ggggttcatt aattgatttt tcatatatat 6060 acaacgggcg tctaattccg gtaatattct attacacaaa tcagattcat actcttctat 6120 tttaggaatg aatacttcaa taggcaaatg acatccaact gcacgtaatg actttattga 6180 taataatgta agccaattga aacttccacc agcaacgtaa actatcccat tcttcttgta 6240 taatccatcg ggggcatctt ccggtaaatt ctcaacaacg tatttgtgag attttttcat 6300 ggcggccaat tcttcgttac tcaattgtaa aaactgggat aaatatttct cactgaatat 6360 agtatcgtca tcggctaatg aatcaaatcg agcatgatat attcttttct tagaaggata 6420 agtgtttaat tgtgacacac tgggtttggc ttgataaaat attttaaaaa tattgtcgaa 6480 aaattcgtat ccttgttgta gtcttttttg ttcaaacggg tgtaatctat tgtatttttc 6540 ttgttgttca ttgattagct ttaaattcaa ttgataggcc tcatccgaca ctaacgattt 6600 cagcagtgtt ttcgttgtag gctcttttgc atgctgctgt tgttgttgtt gctgtttgtg 6660 ttgtgaaatt tcagatgcac ctgattcaac gccgacttct tgattgttgt ttggattaac 6720 ttgaggtttc ttttcttcaa aaggtttggt tttcggtgga aacaacgcca tagttatcga 6780 ttcccataat gaacgatgat atgtaccttt ttcattgata attgctgaat tatcttcagc 6840 gggaagatta ctccaatatg aatatataag aaatattata atgaccagta agaatatgga 6900 attaatgaag atatacttgt gacgacgacg aaacaatcgt agcctataag taagttgttg 6960 aaacatgatt tgtttgtgga ttggaaggag gtatgaaaat cagttgcgaa cactaatgtg 7020 ggctattcga taatgtcgag atactctgga tcagaaacaa acttatagcc acgtttgaga 7080 gcctttagat tcagctatgg cagtaaactt ggtttgtgtt tatttccaac taatgataaa 7140 gagaaaaaat gtattgggga aaaacaaaaa attttgaaaa ttagaattga atgaaaagaa 7200 ttattattct atttggtgtt atttcgtaaa tatggccagc taaagggaca agaaggacgg 7260 aagggaaaga atgggaaaag aaggaaaaaa gaaaatgtat gtaccaatgt gaaaaatgaa 7320 aaagttcttt cttaactata aaagaataag gaaaccaagc caaactcttt tagttttttt 7380 ttttcgttcc ttcttcaagg cgtgttttag tgttggtcac caattacaat caatccaact 7440 ttggaaattt gatctagaac tggttttttt tacttcttta agtaactaat agagccaatt 7500 cccaagaagt ttagcattcc taaccttatt gagatgtaga atttatttct tttttgtcga 7560 tttgaattga taaagcacat acgagaattg cattatctgc ctttatttct tgaattaaag 7620 aataccagtt gaatgataat taacttgaca agacagagca gaacttaaaa cagttgatgt 7680 gcagatactt gtcaacgtca acaatgctct ttcttttcgt tgttgtcgta ctcttcaacg 7740 cctttcttcc tcccctcagg tgactgccac tagaataaag cttaatattc ctaaaacaca 7800 aaaaaacgat acaaagctta tttgttgatg tggtgggaca aaataagata agtatgatcg 7860 ttctgcaata agccgatgtc tagcaatcgt ggtgttaatc ttctagtgta tgtaatctga 7920 atcgtaacag ttgttgtggc ttagataccc aatttttcgc tcatctcagt gctagcttac 7980 attacagagg atccctagat gtataaatca ctcttggatg taagtatttg gaggaatagt 8040 acccatttgt atctaacatg gcggagcata aaccgtcagt aacaaatttg gcaatatgca 8100 cgaccaatac ttcccagatt cataacagca caacgccaat ggaagaagaa aaaaaaacaa 8160 caacagtatg aaaatcagaa tcaacaatat tgaacaacaa ctgtacaatt ttggtgtgga 8220 atcccttaca tcaattccta ctaagaatca acagtcatgg ccattcaatt tttatttctc 8280 atatctcgac aaggtaaaac cagattatca aaatggtatc aaacgatcct gcaaaaggag 8340 aaatccaaga ttatacgaga attaagcaca ataatattat caagacgagc caaaatgtgt 8400 aatgttttag aatataaaga tttaaagata atttatcgaa gatatgctag tttatttttc 8460 gtcattgggg tgaattctga tgataatgaa ttgattggat tagaaataat tcatcgattt 8520 gttgaacaaa tggataaaat atatggtaat gtttgtgaat tggatattat ttttggattt 8580 gataaggcat atcatatatt ggatgaattg ttgattgatg gatatttaca agaaagttcg 8640 aaacgagaag tgttgaaacg agttaatcaa caagatgaat tggaaaatat ggatgaattt 8700 gaaaacatat tggcatgagt tggaagggtt agaataaagc gtttagctgt tatatacata 8760 tatatatggg tgtaactgtt ggtgcaagtt aatagatgcc gttttaacta ttcattgggt 8820 attatcctaa gtttaaaagt tagctaatac agctgatctt ttgtaaaact tcaactacga 8880 taagtatata gtttgagtgc ttgcatttgt ttctacatta tttgattgtc taaattttta 8940 catactattt caattacggt tttgtttcat tttccccatt ttttggaaac atttcttgta 9000 tgaaaaactt gaattagctt actggcaaat tcattgacat tgtttcaata aaagtagatt 9060 tatcagttct tgtttctgta aatttttgta ttgaataaca gtatgatgta atttatgaat 9120 atacgcgtct tcagggtttt actcgtgttt tctcatacta gttttctctc gtctaaatat 9180 gatggaaata atttacatct atactatatg tgccgataca gggagtacac tgtaatgaag 9240 atcaaacaca tgaggtggag acgacagaaa acaaaggaaa atgtagaaaa tccaagaaaa 9300 catcaacata cattagtgca taacagttac tagatttagt gaggtgattt cgtgttttat 9360 tcaggtacac atcccccgcc ccaccaaata tattttgaaa cacacattat tgaaggtgcc 9420 taatgcaata taggataatg gcagcaacga catttttttt cattcggcag aagatctagg 9480 tccattacaa cattagtgaa cttgaaacaa ttgcttgtgg gcaaatcgca acttaataga 9540 caatcattct cttgtgggag agaggggtgt gaataagtaa cgaacatcta aacttttact 9600 tgaaaaaaag gcaaaaaact tgagttttgt gctttatttg ttgtaattag taacagttca 9660 aggaggctag taagtatttt gctgccattc acgagtcgtt aatctgcgta tacggacacg 9720 aatggttgtt ggtgacttct gttctgtaaa gaataaataa tagatatttg ataattcaac 9780 agagccacat ttgcactgtt gtatagcttt acaactacac gttgaaaaga agagctgtat 9840 aaaattagtg atgtaatctg agactggaag atctaatcct tacaaaagtt ctgtttgctt 9900 gcagatgttt cagaaatgac atagttttca atttcgattt tcgtttgtgt gttttgtatg 9960 tgaatttatc gacaattgat attatccaag ccaatcaaaa aagagctccc agtaatttaa 10020 gaccaactat gagctatgtt tctagctgat tgtgcatttt caggtcacat aagtattgct 10080 cgttaggtgt gcaagcaaag tgtatgtgta attcgtaaat tgggataatc acaatagaag 10140 acaagaaaga ctaataaact gagagcttaa tccatttaga tagagttttg atgacatctg 10200 tgtttagagt tgcaagtaat tttcttgtca ttataattgt ggattgagaa ttgtgtgtgg 10260 ggagattgtc aagaagaagt ttctacattt gactggctta tgacgtcata aatctctgtt 10320 tcattaaagt tctattgttc ggttatcgtg cttaaaaaag acgagtcagg agaagctaga 10380 agaagaaaaa aacagaaata ttcaattaat atgcataaag gagaaaacta gaagacgaca 10440 ttttatacat tatacaatag acaacaatct attagattgg cataggttgt gagaagtggt 10500 taaaattata gataacaaaa cctatattta gaatatatga tgaagaaata aacaaacatc 10560 caacgtattg gagtatcctt tctttttttc ttcttctaca aaaagtagac ggtcattcag 10620 aattgacaaa ttgcagttaa agtcaagtct tatgaaacaa tctgagtgat gaaagaaagt 10680 ggcagtgaat tacatattgt caggatatgt tgtagaacct caaacattgt tgtttttagt 10740 agttcttgct cgaaagttgt attaaattgc tagtgctgct gctggtgcta gtggaaaagt 10800 cggcttatgg gtatgtgcca atcgttccaa gcattaatta agaaattata gatttgcttc 10860 ccaagtaact ctaattttat ttttctcttt ggaaagtagt gtttccactt gcgggcaaac 10920 ttaattttgt tttttttcct aatacggatg atgttaaaat cgtggttatt tgttgcataa 10980 tatcgatgga ttattgttat ttgttacccc ttgcaaatac taaaacgagt aatattcaca 11040 catagtgttt acacattgta gtggcaaaga tcacaatata ttgttttctt acattaaact 11100 tttgtaaagc agccattatg taacgaaaaa gactcctggt gtttggagat caacagcaat 11160 agcaataata tcattataaa tgagtcatca ggcaatatta tgcaagagtt caaaatagtt 11220 gtgttttaac aacaagcttt ctacataaca tacttcttgg tgtgattacc acggttattc 11280 aagtgcaatt aagctattaa gtgcaaatcc aagggaatgt gtacataggt tgaattattt 11340 tcggaaatac gttaaatctc gccaagtgta acaacaagat ttttgagcag atccgcaaat 11400 gccttcaaag tagaaaacat atacaagtgc aagagaaaaa ataaaaagct tctgtaggca 11460 ttgacgcttt ttgcaaattt aaagtagata ttttcagatg ggagtctatg aaaaaaaaaa 11520 agctttaccc aacaataata ataattacga acttaatcaa ccaaaatcat gtgtgttaaa 11580 atagactttg gggttttctt attctattgt aattaggtta acgtatttgt taacgttcta 11640 tttacattat atgtgtaaac caagccaaat ataagaaagt agaacccact tattgaatag 11700 tatactaatt tacttgaatt taaaatttat tactgctaat acttttttgt ttgactttgt 11760 ttgactcctg ttcccttttt ttctgacgaa tatttgtatg tgccaaagtg gtgtgtatgg 11820 tgacgatggt gggtggtgtt ttacccaaat attttattcc acacaaatta caaagaaaac 11880 actggaagca aaaaaaaaat ttgtttacac gaaaaaaaaa acctgcagga acgacttgga 11940 cgacattttt cgagaaaaaa aatccctcat agttaaaaag tacgtgcttt ttgaaaatgc 12000 ttagaagctt aaaaaaaaaa tcacccgaca ttgtgattaa tttaccagaa cccaaaaaaa 12060 aaaaaatccg tccaagcact accgccagaa aaaaaatgta ttacctcctc ttcctgcctc 12120 cacttccttt gcctccgcac gcacatacac atacacacac tcgcacacgc acacgcatct 12180 ccatttgata cacattgacc gacattattg ttgtttttag aagaaagttg tttcacaact 12240 gaacaaacag aattagtttg aataatatgt tctctgcctc cccaaagctt acccctaaaa 12300 cattatgtaa tggtttacga ttttactagt aaaatctagt attatgtcgt cagtttatag 12360 ttcctgtatt tgaaactttg catacaaaaa aataatagaa ataaaaatgg aaaagtataa 12420 agacataatt ttcccactac aatattcttc attttttttt tttattttag tttgtaccat 12480 tcaaagaaaa aaaaaaaatt tttcttttag ctctgtttta ttttgtttgt gaattgaatt 12540 tttttttttc cctccaggag tatttaataa tcattaaatt tctcccaact tcaaaaaaaa 12600 aacttcattt cttttaaaaa aaattttata ttacttgtgg gatatatctt tccattaata 12660 ttcaatttta ataaattggt tgttgttaca gataacgttc catttcctta gtatttggtg 12720 tataacattt gttgtttgtt tgggttgatt ccattccaca acttccactc ccccctaaat 12780 tggaaaaaga ttttttttct tcttcacacc ataacaacca cttaagagac gagtctactt 12840 attttaattt tcctctgtgt gttgaaaata caacaagact gactggtatt ccccattatt 12900 ttaattggtg aacatttcaa tcgtcattat aagaa 12935 // |
|