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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAK43943; SV 1; linear; genomic DNA; STD; FUN; 1428 BP.
XX
PA   AM269976.1
XX
DE   Aspergillus niger hypothetical protein
XX
OS   Aspergillus niger
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae;
OC   Aspergillus.
OX   NCBI_TaxID=5061;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1428
FT                   /organism="Aspergillus niger"
FT                   /mol_type="genomic DNA"
FT                   /clone="An01c0290"
FT   CDS             complement(join(AM269976.1:151377..152105,
FT                   AM269976.1:152161..152535,AM269976.1:152622..152836,
FT                   AM269976.1:152914..153022))
FT                   /locus_tag="An01g08540"
FT                   /note="Remark: K3OH is involved in metabolism of tryptophan
FT                   to kynurenic acid (KYNA), which has anticonvulsant and
FT                   neuroprotective activities, and quinolinic acid (QUIN)
FT                   which is neurotoxic, and is a target for inhibition of QUIN
FT                   synthesis."
FT                   /note="Remark: patent WO9802553."
FT                   /note="Title: strong similarity to kynurenine 3-hydroxylase
FT                   K3OH from patent WO9802553 - Rattus sp."
FT                   /db_xref="GOA:A2Q9N7"
FT                   /db_xref="InterPro:IPR003042"
FT                   /db_xref="UniProtKB/Swiss-Prot:A2Q9N7"
FT                   /inference="profile:COGS:COG0654"
FT                   /inference="profile:PFAM:PF01360"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAK43943.1"
FT                   /translation="MSSYKVVIVGGGPVGALAGLYAAQRGFQVEIYEMRDEYSQVQTAT
FT                   AFSAKSISLTLSERGIKALRHSQCRGLAERILSTTVPVYGRMVHSRSKKRLTSRRIAYD
FT                   VHGQALYAISRSEINQSLLEELSAFPNVHIFYKHRLNGLDMKQKCATFHNISRPQEPSH
FT                   ETKFDLLIGADGAHSTTRFFLSRYAKININQKWEDIFWCELTIPAGHALPMDCLHMWPQ
FT                   RDFMLFACPDKEGTLTCNLFAPENVFLELKSSGRIVEFFEKNFPGITPDLIPTDNLQKQ
FT                   FKSNLHHPMIDIRCSPYHYQDSCVLIGDAAHAMVPFYGQGMNTGFEDVRILFEDFLDQR
FT                   RSFPSWKDNLSLSYAMQQKELPDTPQAIVEDYLEQYTKYRQPDVHIINELALQNYRELR
FT                   QGVFKMSYHIRKHIEEFLSLHAPQLGWATQYRLVAFETMRYTDVLRQVRKQGLILSAVA
FT                   WSCLLLFFLLCLLSLRL"
XX
SQ   Sequence 1428 BP; 343 A; 375 C; 355 G; 355 T; 0 other; 1769102934 CRC32;
     atgtcttcat acaaggttgt tattgtcggg ggtggtcccg ttggggcatt ggcgggttta        60
     tatgcggctc agcgaggctt tcaagtggaa atttatgaga tgagggacga gtacagtcag       120
     gttcagacag cgactgcctt ctctgccaag agtatcagtc tgacgctgtc tgagcgaggc       180
     atcaaggcct tgcggcatag ccaatgcagg ggcctggcag agaggatcct atcgacgact       240
     gtccccgtct atggtcgaat ggtgcacagc aggtccaaga agcgactaac atccagacgg       300
     attgcttatg atgttcatgg acaggccctt tatgctatca gccgctccga gatcaaccaa       360
     agcttgctag aagagctgtc tgccttccct aatgtccaca tattctacaa gcacaggctc       420
     aatggcttgg acatgaagca gaagtgtgcc actttccata acatctctcg accccaggag       480
     cccagtcatg agaccaagtt tgacctactg atcggtgccg atggtgctca ctctacaacc       540
     cgcttctttc tgtcccgcta tgcgaagatt aatatcaatc agaagtggga ggatatcttc       600
     tggtgtgagc taaccatccc tgcgggtcat gcccttccga tggactgtct gcacatgtgg       660
     ccccaacgag actttatgct gtttgcctgt ccggacaagg aaggaacact gacttgcaat       720
     ttgttcgccc cggaaaacgt cttcctagaa ctgaaatcct ctggaaggat cgtagagttc       780
     tttgaaaaga acttccccgg tatcacacca gacctcatcc ccaccgacaa tctccagaag       840
     caattcaagt caaatcttca tcaccccatg atcgatatcc gatgctcacc gtatcactac       900
     caggattcat gtgtcctgat tggcgatgct gcacacgcca tggtcccctt ctacggccaa       960
     ggcatgaaca ccggcttcga agatgtccga attctattcg aggattttct tgaccaacga      1020
     aggagtttcc cctcctggaa ggacaatctc tccttgagtt atgcgatgca acaaaaagaa      1080
     ctacccgaca ccccccaagc gattgtggaa gactacctcg agcagtacac caagtatcgc      1140
     cagccggacg tccacattat aaatgaactg gcgttgcaaa actacaggga gctaagacaa      1200
     ggcgtgttca agatgtctta ccatatccgc aagcatattg aagagtttct gagtctccat      1260
     gccccgcagc ttgggtgggc gacgcagtac cggctggtgg cgtttgagac gatgcgatat      1320
     accgatgttt tgcgacaggt ccgaaagcag ggtctgatct tgagtgcggt ggcgtggagc      1380
     tgcctgctgc tctttttcct tttgtgtctt ttgtcgcttc gtctgtaa                   1428
//
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