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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAE55363; SV 1; linear; genomic DNA; STD; PRO; 1401 BP.
XX
PA   BX842575.1
XX
DE   Mycobacterium tuberculosis H37Rv PROBABLE GLUCOSE-6-PHOSPHATE
DE   1-DEHYDROGENASE ZWF1 (G6PD)
XX
OS   Mycobacterium tuberculosis H37Rv
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1401
FT                   /organism="Mycobacterium tuberculosis H37Rv"
FT                   /strain="H37Rv"
FT                   /mol_type="genomic DNA"
FT   CDS             BX842575.1:209920..211320
FT                   /transl_table=11
FT                   /gene="zwf1"
FT                   /locus_tag="Rv1121"
FT                   /standard_name="zwf"
FT                   /product="PROBABLE GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE ZWF1
FT                   (G6PD)"
FT                   /function="INVOLVED IN PENTOSE PHOSPHATE PATHWAY (FIRST
FT                   STEP) [CATALYTIC ACTIVITY : D-GLUCOSE 6-PHOSPHATE + NADP(+)
FT                   = D-GLUCONO-1,5-LACTONE 6-PHOSPHATE + NADPH.]"
FT                   /EC_number="1.1.1.49"
FT                   /note="Rv1121, (MTCY22G8.10), len 466 aa. Probable zwf1,
FT                   glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49), highly
FT                   similar to many e.g. G6PD_E COLI|P22992 Escherichia coli
FT                   (491 aa), FASTA scores: opt: 642, E(): 0, (35.8% identity
FT                   in 478 aa overlap). Mycobacterium tuberculosis has two
FT                   genes for ZWF, this one is highly divergent. BELONGS TO THE
FT                   GLUCOSE-6-PHOSPHATE DEHYDROGENASE FAMILY. Note that
FT                   previously known as zwf."
FT                   /db_xref="GOA:P0A586"
FT                   /db_xref="HSSP:1QKI"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A586"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAE55363.1"
FT                   /translation="MVDGGGGASDLLVIFGITGDLARKMTFRALYRLERHQLLDCPILG
FT                   VASDDMSVGQLVKWARESIGRTEKIDDAVFDRLAGRLSYLHGDVTDSQLYDSLAELIGS
FT                   ACRPLYYLEMPPALFAPIVENLANVRLLERARVAVEKPFGHDLASALELNARLRAVLGE
FT                   DQILRVDHFLGKQPVVELEYLRFANQALAELWDRNSISEIHITMAEDFGVEDRGKFYDA
FT                   VGALRDVVQNHLLQVLALVTMEPPVGSSADDLNDKKAEVFRAMAPLDPDRCVRGQYLGY
FT                   TEVAGVASDSATETYVALRTEIDNWRWAGVPIFVRAGKELPAKVTEVRLFLRRVPALAF
FT                   LPNRRPAEPNQIVLRIDPDPGMRLQISAHTDDSWRDIHLDSSFAVDLGEPIRPYERLLY
FT                   AGLVGDHQLFAREDSIEQTWRIVQPLLDNPGEIHRYDRGSWGPEAAQSLLRGHRGWQSP
FT                   WLPRGTDA"
XX
SQ   Sequence 1401 BP; 240 A; 428 C; 465 G; 268 T; 0 other; 2051408007 CRC32;
     ttggttgacg gcggaggtgg cgcgtcagat ctgttggtga tcttcggaat taccggtgac        60
     ctggcccgca agatgacctt ccgcgcgttg tatcggctcg agcgccacca gttgctggac       120
     tgccccatcc tgggtgtggc cagtgacgac atgtccgtcg ggcagttggt caagtgggct       180
     cgcgagtcca tcggtcgtac cgaaaagatc gacgatgcgg tgttcgaccg gttggcgggc       240
     cggttgtcct acctgcacgg tgacgtcacc gacagccagc tctacgattc gctggccgaa       300
     ctgattggct cggcctgtcg gccgctgtat tacctggaaa tgccgccggc gctgttcgcg       360
     ccgattgtcg aaaatctcgc gaacgtgcgg ctgttggagc gcgcacgcgt tgccgtggaa       420
     aagccgttcg gccacgacct ggcctccgcg ctcgaactca acgcccggct gcgagcggtg       480
     ttgggcgaag accaaatcct gcgtgtggac cactttctgg gcaagcagcc cgtcgtcgag       540
     ctggagtacc tgaggttcgc caatcaggcg ttagccgagc tctgggatcg caacagcatc       600
     tccgagatcc acatcaccat ggccgaggac ttcggggtgg aggaccgcgg caagttttac       660
     gacgccgtcg gtgccctgcg tgacgtcgtg caaaaccatc tgctgcaggt gctggcgctg       720
     gtgacgatgg aaccgccggt cggttccagc gccgatgacc tcaacgacaa gaaggccgag       780
     gtcttccggg cgatggcgcc gctggatccc gatcggtgcg tgcgtgggca gtacctcggc       840
     tacaccgaag ttgcgggcgt agcaagcgat tcggcgaccg aaacgtatgt cgcgctgcga       900
     accgagatcg acaactggcg ctgggccggg gtgccgatct tcgtgcgggc cggaaaagag       960
     ctgcccgcga aggtcaccga agtacggcta tttttacgcc gagttccggc attggccttt      1020
     ctgcccaacc gccgaccggc cgagcccaac cagattgtgc tgcgtatcga ccccgatccg      1080
     ggtatgcgac tgcagatttc ggcccacacc gacgactcgt ggcgagatat ccacctggac      1140
     tcctcgttcg cggtggacct cggtgaaccg atacgaccct atgagcggct gctgtatgcc      1200
     ggattggtcg gcgatcacca gttgttcgcc cgcgaggaca gcatcgagca gacgtggcgg      1260
     atcgtgcagc cgctgctcga caacccgggt gaaatccatc ggtacgatcg cggttcctgg      1320
     ggtccggaag ccgcgcagtc gttgctgcgc ggtcaccgcg gttggcagtc gccgtggctg      1380
     ccccgcggca cggacgcatg a                                                1401
//
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