EBI Dbfetch

ID   CAD96245; SV 1; linear; genomic DNA; STD; PRO; 1752 BP.
XX
PA   BX248339.1
XX
DE   Mycobacterium bovis AF2122/97 PROBABLE FUMARATE REDUCTASE [FLAVOPROTEIN
DE   SUBUNIT] FRDA (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)
XX
OS   Mycobacterium bovis AF2122/97
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1752
FT                   /organism="Mycobacterium bovis AF2122/97"
FT                   /strain="AF2122/97"
FT                   /mol_type="genomic DNA"
FT   CDS             BX248339.1:127696..129447
FT                   /transl_table=11
FT                   /gene="frdA"
FT                   /locus_tag="Mb1578"
FT                   /product="PROBABLE FUMARATE REDUCTASE [FLAVOPROTEIN
FT                   SUBUNIT] FRDA (FUMARATE DEHYDROGENASE) (FUMARIC
FT                   HYDROGENASE)"
FT                   /EC_number="1.3.99.1"
FT                   /note="Mb1578, frdA, len: 583 aa. Equivalent to Rv1552,
FT                   len: 583 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100% identity in 583 aa overlap). Probable frdA, fumarate
FT                   reductase, flavoprotein subunit (EC 1.3.99.1), highly
FT                   similar to others e.g. P00363|FRDA_ECOLI fumarate reductase
FT                   flavoprotein subunit from Escherichia coli strain K12 (601
FT                   aa), FASTA scores: opt: 2102, E(): 0, (54.7% identity in
FT                   585 aa overlap); NP_232284.1|NC_002505 fumarate reductase,
FT                   flavoprotein subunit from Vibrio cholerae (602 aa);
FT                   frdA|NP_438995.1|NC_000907 fumarate reductase, flavoprotein
FT                   subunit from Haemophilus influenzae (599 aa); etc. Contains
FT                   PS00504 Fumarate reductase / succinate dehydrogenase
FT                   FAD-binding site. NOTE THAT FUMARATE REDUCTASE FORMS PART
FT                   OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A
FT                   FLAVOPROTEIN (Rv1552|frdA), AN IRON-SULFUR (Rv1553|frdB),
FT                   AND TWO HYDROPHOBIC ANCHOR PROTEINS (Rv1554|frdC and
FT                   Rv1555|frdD)."
FT                   /db_xref="GOA:P64175"
FT                   /db_xref="HSSP:1KF6"
FT                   /db_xref="InterPro:IPR014006"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64175"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAD96245.1"
FT                   /translation="MTAQHNIVVIGGGGAGLRAAIAIAETNPHLDVAIVSKVYPMRSHT
FT                   VSAEGGAAAVTGDDDSLDEHAHDTVSGGDWLCDQDAVEAFVAEAPKELVQLEHWGCPWS
FT                   RKPDGRVAVRPFGGMKKLRTWFAADKTGFHLLHTLFQRLLTYSDVMRYDEWFATTLLVD
FT                   DGRVCGLVAIELATGRIETILADAVILCTGGCGRVFPFTTNANIKTGDGMALAFRAGAP
FT                   LKDMEFVQYHPTGLPFTGILITEAARAEGGWLLNKDGYRYLQDYDLGKPTPEPRLRSME
FT                   LGPRDRLSQAFVHEHNKGRTVDTPYGPVVYLDLRHLGADLIDAKLPFVRELCRDYQHID
FT                   PVVELVPVRPVVHYMMGGVHTDINGATTLPGLYAAGETACVSINGANRLGSNSLPELLV
FT                   FGARAGRAAADYAARHQKSDRGPSSAVRAQARTEALRLERELSRHGQGGERIADIRADM
FT                   QATLESAAGIYRDGPTLTKAVEEIRVLQERFATAGIDDHSRTFNTELTALLELSGMLDV
FT                   ALAIVESGLRREESRGAHQRTDFPNRDDEHFLAHTLVHRESDGTLRVGYLPVTITRWPP
FT                   GERVYGR"
XX
SQ   Sequence 1752 BP; 340 A; 546 C; 564 G; 302 T; 0 other; 3803588636 CRC32;
     atgaccgccc aacacaacat cgtggttatc ggcggcggtg gtgcgggtct gcgcgccgcg        60
     attgcgatag ccgaaaccaa tccgcacctg gatgtggcga tcgtttccaa ggtgtacccg       120
     atgcgcagcc acaccgtctc ggctgagggc ggcgccgcgg cggtgaccgg tgacgacgac       180
     agcctcgatg aacacgcgca cgacacggta tccggtggcg actggctgtg tgaccaagat       240
     gcggtcgagg ctttcgtggc cgaggcgccc aaagagttgg tgcagctcga gcattggggc       300
     tgtccgtgga gccgtaaacc agacgggcgc gttgccgttc gcccgttcgg cgggatgaag       360
     aagctgcgca cctggtttgc cgccgacaag acgggatttc acctcctgca cacgttgttt       420
     caacggctgc tcacctattc cgacgtcatg cgctatgacg agtggttcgc tacgacgctg       480
     ctggtcgacg acggcagggt atgtggtctg gtcgctatcg agttggcgac cgggcgcatc       540
     gagacgatcc ttgccgacgc ggtgattctg tgcaccggcg gatgcgggcg ggtatttcca       600
     ttcaccacca acgcgaacat caagaccggc gacggcatgg cgctcgcatt ccgcgcgggc       660
     gcgcccctaa aagacatgga attcgtccaa taccacccca ccggactgcc gttcaccggg       720
     atcttgatca ccgaggccgc acgagctgaa ggcggctggc tgctcaacaa agacggctac       780
     cgctacctcc aggattacga cctcggcaag cccacgcccg agcccaggct gcgcagtatg       840
     gagctcgggc ccagggaccg actgtcgcag gccttcgtac acgagcacaa caaaggaagg       900
     acggtcgaca ccccgtacgg ccccgtcgtc tatctagacc tgcggcacct gggggcggac       960
     ctgatcgatg caaagttgcc gttcgtacgt gagctgtgcc gcgactacca gcacatcgac      1020
     cccgtggtcg aattggtccc ggtacgaccg gtagtgcact acatgatggg tggcgttcac      1080
     accgatatca acggcgccac aacgcttccc gggctatatg ccgcaggtga aacagcctgc      1140
     gtgagcatta atggcgccaa ccgcctgggg tcgaactcgc tgcccgagct gctggtgttc      1200
     ggggctcgag cgggccgtgc cgccgcggat tacgcagcgc gccaccaaaa gtcggaccgt      1260
     ggcccgtcgt cggcagtgcg ggctcaggcc cgcaccgagg ctctacggct agagcgtgag      1320
     ctcagccgcc atggccaggg aggcgaacga atcgcggata ttcgggcgga catgcaggcc      1380
     accttggaaa gcgccgcggg tatttatcgt gacggaccca ccctcaccaa agcggtcgag      1440
     gagattcggg tgctgcagga acgattcgcc acggcgggca tcgacgatca cagccgcaca      1500
     ttcaacaccg agctgactgc gctgctcgag ttgtcgggga tgctcgacgt tgcactggcg      1560
     atcgtcgaat ctggtttgcg ccgagaagaa tcccgtggcg cacaccagcg aaccgacttt      1620
     ccgaaccggg acgacgagca tttcttggcg cacaccttgg ttcatagaga aagcgacgga      1680
     acgctgcggg tcggctacct tccggtcact atcactcgct ggccaccggg cgaacgcgtg      1740
     tatgggaggt aa                                                          1752
//