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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAD93635; SV 1; linear; genomic DNA; STD; PRO; 885 BP.
XX
PA   BX248336.1
XX
DE   Mycobacterium bovis AF2122/97 PROBABLE 3-HYDROXYISOBUTYRATE DEHYDROGENASE
DE   MMSB (HIBADH)
XX
OS   Mycobacterium bovis AF2122/97
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..885
FT                   /organism="Mycobacterium bovis AF2122/97"
FT                   /strain="AF2122/97"
FT                   /mol_type="genomic DNA"
FT   CDS             complement(BX248336.1:177537..178421)
FT                   /transl_table=11
FT                   /gene="mmsB"
FT                   /locus_tag="Mb0773c"
FT                   /product="PROBABLE 3-HYDROXYISOBUTYRATE DEHYDROGENASE MMSB
FT                   (HIBADH)"
FT                   /EC_number="1.1.1.31"
FT                   /note="Mb0773c, mmsB, len: 294 aa. Equivalent to Rv0751c,
FT                   len: 294 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 294 aa overlap). Probable mmsB,
FT                   3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31), highly
FT                   similar to others e.g. NP_102847.1|NC_002678
FT                   3-hydroxyisobutyrate dehydrogenase from Mesorhizobium loti
FT                   (294 aa); NP_420167.1|NC_002696 3-hydroxyisobutyrate
FT                   dehydrogenase from Caulobacter crescentus (298 aa); A32867
FT                   3-hydroxyisobutyrate dehydrogenase from Rattus norvegicus
FT                   (346 aa); etc. Also similar to methylmalonate semialdehyde
FT                   dehydrogenases e.g. M84911|PSE MMSRAB_3 methylmalonate
FT                   semialdehyde dehydrogenase from Pseudomonas aeruginosa (298
FT                   aa), FASTA scores: opt: 786, E(): 0, (45.8% identity in 297
FT                   aa overlap). Also similar to 6-phosphogluconate
FT                   dehydrogenases from Mycobacterium tuberculosis e.g. Rv1122
FT                   and Rv1844c. Contains PS00895 3-hydroxyisobutyrate
FT                   dehydrogenase signature. BELONGS TO THE
FT                   3-HYDROXYISOBUTYRATE DEHYDROGENASE FAMILY."
FT                   /db_xref="GOA:P63936"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63936"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAD93635.1"
FT                   /translation="MTTIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGV
FT                   AVFRSAPEAVAEADVVITMLPTGEVVRRCYTDVLAAARPATLFIDSSTISVTDAREVHA
FT                   LAESHGMLQLDAPVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGA
FT                   GQAAKVCNNMVLAVQQIAIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGP
FT                   VPTSPANNDFKPGFSTALMNKDLGLAMDAVAATGATAPLGSHAADIYAKFAADHADLDF
FT                   SAVIHTLRARADA"
XX
SQ   Sequence 885 BP; 139 A; 305 C; 304 G; 137 T; 0 other; 1970518885 CRC32;
     atgacgacca tcgccttcct aggtttgggc aacatgggtg cgccgatgtc ggcgaatctg        60
     gttggtgcgg gccacgtcgt gcgtggattc gacccggcac ccacggcggc gtccggcgcc       120
     gccgcgcacg gtgtcgcggt gtttcgtagc gcgcccgaag cggtggccga ggccgacgtg       180
     gtcatcacca tgctgcccac cggcgaggtg gtccggcgct gctacaccga cgtgctggcc       240
     gccgcgcgtc cggcaacgct gttcatcgac agctccacga tctcggtcac cgatgcccgt       300
     gaggtgcacg cgctggccga atcgcacggc atgctccaac tggatgcgcc ggtctccggc       360
     ggggtgaagg gcgccgccgc cgcgacgctg gcattcatgg tcggcggcga cgagtccacg       420
     ctacggcggg cacgcccggt actagagccc atggcgggca agatcattca ctgcggcgcc       480
     gccggtgccg gacaggccgc caaggtgtgc aacaacatgg tgctggcggt gcagcagatc       540
     gcgatcgccg aggcgttcgt gctggccgag aagctcgggc tgtccgcaca atcgttgttc       600
     gacgtcatca ccggcgcgac cggcaattgc tgggcggtgc acaccaattg cccggtgccg       660
     ggcccggtgc ccacctcacc ggccaacaac gacttcaagc ccgggttttc gaccgcgttg       720
     atgaacaagg acctgggcct ggcgatggat gcggtggccg ccaccggtgc gacggccccg       780
     ctgggcagcc acgccgccga catctacgcc aaattcgccg ccgaccacgc cgacctggac       840
     ttcagcgcgg tgatccacac gttgcgcgcg cgagcagacg cataa                       885
//
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