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EBI DbfetchID CAD93103; SV 1; linear; genomic DNA; STD; PRO; 1536 BP. XX PA BX248334.1 XX DE Mycobacterium bovis AF2122/97 PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE DE [NADP+] DEPENDANT (SSDH) GABD1 XX OS Mycobacterium bovis AF2122/97 OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Corynebacterineae; Mycobacteriaceae; Mycobacterium; OC Mycobacterium tuberculosis complex. OX NCBI_TaxID=233413; XX FH Key Location/Qualifiers FH FT source 1..1536 FT /organism="Mycobacterium bovis AF2122/97" FT /strain="AF2122/97" FT /mol_type="genomic DNA" FT CDS complement(BX248334.1:277929..279464) FT /transl_table=11 FT /gene="gabD1" FT /locus_tag="Mb0239c" FT /standard_name="gabD2" FT /product="PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE FT [NADP+] DEPENDANT (SSDH) GABD1" FT /EC_number="1.2.1.16" FT /note="Mb0239c, gabD1, len: 511 aa. Equivalent to Rv0234c, FT len: 511 aa, from Mycobacterium tuberculosis strain H37Rv, FT (100.0% identity in 511 aa overlap). Probable gabD1, FT succinate-semialdehyde dehydrogenase [NADP+] dependent (EC FT 1.2.1.16), equivalent to AL022486|MLCB1883_6 PROBABLE FT ALDEHYDE DEHYDROGENASE from Mycobacterium leprae (457 aa), FT FASTA scores: opt: 2617, E(): 0, (85.7% identity in 455 aa FT overlap). Also highly similar to Q55585|GABD|SLR0370 FT PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE from FT Synechocystis sp. strain PCC 6803 (454 aa), FASTA scores: FT opt: 1676, E(): 0, (55.8% identity in 455 aa overlap); and FT similar to others e.g. GABD_ECOLI|P25526 FT succinate-semialdehyde dehydrogenase from Escherichia coli FT (482 aa), FASTA scores: opt: 929, E(): 0, (36.5% identity FT in 452 aa overlap); etc. Note that similar to other FT cytosolic aldehyde dehydrogenases with EC number: 1.2.1.3. FT Also similar to Rv0768|aldA semialdehyde dehydrogenase from FT Mycobacterium tuberculosis (489 aa); and FT gabD2|Rv1731|MTCY04C12.16 POSSIBLE SUCCINATE-SEMIALDEHYDE FT DEHYDROGENASE [NADP+] DEPENDANT from Mycobacterium FT tuberculosis (518 aa). Contains PS00070 aldehyde FT dehydrogenases cysteine active site. BELONGS TO THE FT ALDEHYDE DEHYDROGENASES FAMILY. Could start at different FT site by homology. Note that previously known as gabD2." FT /db_xref="GOA:Q7U2I0" FT /db_xref="HSSP:1CW3" FT /db_xref="InterPro:IPR015590" FT /db_xref="UniProtKB/Swiss-Prot:Q7U2I0" FT /experiment="experimental evidence, no additional details FT recorded" FT /func_characterised="similar sequence" FT /protein_id="CAD93103.1" FT /translation="MRSVTCSATLVLPVIEPTPADRRPRHLLLGSAGHVSGRLDTGRFV FT QTHPAKDVSVPIATINPATGETVKTFTAATDDEVDAAIARAHRRFADYRQTSFAQRARW FT ANATADLLEAEADQAAAMMTLEMGKTLAAAKAEALKCAKGFRYYAENAEALLADEPADA FT AKVGASAAYGRYQPLGVILAVMPWNFPLWQAVRFAAPALMAGNVGLLKHASNVPQCALY FT LADVIARGGFPDGCFQTLLVSSGAVEAILRDPRVAAATLTGSEPAGQSVGAIAGNEIKP FT TVLELGGSDPFIVMPSADLDAAVSTAVTGRVQNNGQSCIAAKRFIVHADIYDDFVDKFV FT ARMAALRVGDPTDPDTDVGPLATEQGRNEVAKQVEDAAAAGAVIRCGGKRLDRPGWFYP FT PTVITDISKDMALYTEEVFGPVASVFRAANIDEAVEIANATTFGLGSNAWTRDETEQRR FT FIDDIVAGQVFINGMTVSYPELPFGGVKRSGYGRELSAHGIREFCNIKTVWIA" XX SQ Sequence 1536 BP; 277 A; 527 C; 499 G; 233 T; 0 other; 2844009703 CRC32; atgcgatcgg tgacatgttc cgccacgctg gtcctgcccg tgatagagcc caccccagcc 60 gataggaggc cccgacacct cctgctcggg agcgctggcc acgttagtgg caggctggac 120 accggacgat ttgtgcaaac ccacccagca aaggatgtca gcgtgcccat cgccaccatc 180 aacccggcta ccggcgaaac agtcaagaca ttcactgcgg cgaccgatga cgaagtcgac 240 gcggcaatag cccgggccca ccggcggttc gccgactacc gccagaccag cttcgcccag 300 cgcgcccggt gggccaatgc caccgccgac ttgctggaag ccgaggccga ccaggccgcc 360 gcgatgatga cgctcgagat gggcaagacg ctggccgcgg ccaaagccga ggcactgaag 420 tgcgccaagg gttttcgcta ctacgccgaa aacgccgagg cgttgctggc cgacgaaccc 480 gccgatgcgg ccaaggtcgg ggcgtcggcg gcctacggcc gataccagcc gctcggggtg 540 atcctggcgg tgatgccatg gaacttcccc ctgtggcaag cggttcggtt cgccgcaccg 600 gcactgatgg ccggaaacgt cggcctgctc aagcacgcgt cgaacgtgcc gcaatgcgcg 660 ctgtacctgg ccgacgtcat cgcccgaggc ggcttcccgg acggctgctt ccagacgttg 720 cttgttagct cgggagccgt cgaagccatc ctgcgtgatc cccgggtcgc ggcggccacg 780 ctgaccggaa gcgagccggc cggccaatcg gtgggcgcta tcgccggtaa cgagatcaag 840 ccgaccgtgc tcgagctcgg cggcagcgac ccgttcatcg ttatgccgtc ggccgatctg 900 gacgccgcgg tcagcaccgc cgtcaccggc cgggtgcaga acaacggcca atcctgcatc 960 gccgccaagc ggttcatcgt ccacgccgac atttacgacg atttcgtcga caagttcgtc 1020 gcgcggatgg cggcgttacg ggtcggcgac ccgaccgacc cggacaccga cgtgggcccg 1080 ctggccaccg agcagggccg caacgaggtt gccaagcaag tcgaggatgc tgccgcggcg 1140 ggcgcggtga tccggtgcgg cggaaagcgt ctcgaccggc cgggctggtt ctacccgccg 1200 accgtgatca ccgacatctc caaggacatg gctctctaca ccgaggaggt cttcggtccg 1260 gtcgcctcgg tgttccgcgc ggcgaacatc gacgaggccg tcgagatcgc caacgccacc 1320 accttcgggc tgggatccaa cgcctggacc cgcgacgaga ccgagcaacg acgcttcatc 1380 gacgacatcg tggcgggcca ggtttttatc aacggcatga cggtgtccta tcccgaattg 1440 ccgttcggcg gggtcaagcg ctcgggctat ggccgggaac tgtccgcaca cgggatacgc 1500 gagttctgca acatcaagac cgtctggatc gcctag 1536 // |
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