spacer
spacer
EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAC30469; SV 1; linear; genomic DNA; STD; PRO; 498 BP.
XX
PA   AL583922.1
XX
DE   Mycobacterium leprae dihydrofolate reductase
XX
OS   Mycobacterium leprae
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium.
OX   NCBI_TaxID=1769;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..498
FT                   /organism="Mycobacterium leprae"
FT                   /strain="TN"
FT                   /mol_type="genomic DNA"
FT   CDS             complement(AL583922.1:151676..152173)
FT                   /transl_table=11
FT                   /gene="folA"
FT                   /gene_synonym="ML1518"
FT                   /product="dihydrofolate reductase"
FT                   /note="Highly similar to many dihydrofolate reductases (EC
FT                   1.5.1.3) including: Escherichia coli SW:DYR_ECOLI (P00379)
FT                   (159 aa); Fasta score E(): 2e-15, 38.4% identity in 146 aa
FT                   overlap and several reductases from Mycobacteria including
FT                   M. tuberculosis RV2763C TR:O30463 (EMBL:AF006616) (181 aa);
FT                   Fasta score E(): 0, 68.9% identity in 161 aa overlap and M.
FT                   avium TR:O30463. Contains Pfam match to entry PF00186
FT                   DiHfolate_red, Dihydrofolate reductase. Contains PS00075
FT                   Dihydrofolate reductase signature."
FT                   /db_xref="GOA:Q9CBW1"
FT                   /db_xref="HSSP:1DF7"
FT                   /db_xref="InterPro:IPR017925"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q9CBW1"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAC30469.1"
FT                   /translation="MTVVGLIWAQSTTGVIGRDGGMPWRVPEDLTRFKQLTMGHPVVMG
FT                   RRTWDSLPVGVRPLPGRRNIVLSRQIDFMAEGAEVFGSLEETISNLETEPEMWVIGGEQ
FT                   IYRLALPLATRCGVTEVDTYLLHEDDDVLAPVLDDTWVGVTGEWLVSCSGLRYRLHSYH
FT                   RS"
XX
SQ   Sequence 498 BP; 84 A; 123 C; 182 G; 109 T; 0 other; 1545823803 CRC32;
     atgacggtgg tgggcctgat ctgggctcag tcgacgacgg gtgtgattgg gcgcgacggc        60
     ggcatgccat ggcgagtgcc tgaggatctg actcgcttca aacagctgac gatgggtcac       120
     ccggtggtga tgggccgacg gacctgggat tcgttgccgg ttggggttcg cccgctgcca       180
     ggccgccgaa atatcgtgtt gagccgacaa attgacttta tggctgaggg agcggaggtg       240
     ttcggttctc tcgaagagac catttccaat ctcgagaccg agcctgagat gtgggtgatt       300
     ggcggtgagc agatctaccg gcttgcgttg ccgctggcga cccgttgcgg ggtcaccgag       360
     gtagacacct acctgcttca tgaggacgat gacgtgctgg ccccggtgct cgacgataca       420
     tgggtgggtg tgacgggaga gtggctggtg agctgctccg ggctgcggta ccggttgcac       480
     agctatcatc gttcatga                                                     498
//
spacer
spacer