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EBI DbfetchID CAC29514; SV 1; linear; genomic DNA; STD; PRO; 3750 BP. XX PA AL583917.1 XX DE Mycobacterium leprae putative DNA gyrase subunit A XX OS Mycobacterium leprae OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Corynebacterineae; Mycobacteriaceae; Mycobacterium. OX NCBI_TaxID=1769; XX FH Key Location/Qualifiers FH FT source 1..3750 FT /organism="Mycobacterium leprae" FT /strain="TN" FT /mol_type="genomic DNA" FT CDS AL583917.1:7318..11067 FT /transl_table=11 FT /gene="gyrA" FT /gene_synonym="ML0006" FT /product="putative DNA gyrase subunit A" FT /EC_number="5.99.1.3" FT /note="Similar to M. tuberculosis gyrA, DNA gyrase subunit FT A, SW:GYRA_MYCTU (Q07702) (838 aa); Fasta score E(): 0, FT 91.1% identity in 695 aa overlap and to Mycobacterium FT smegmatis gyrA, SW:GYRA_MYCSM (P48354) (842 aa); Fasta FT score E(): 0, 88.2% identity in 692 aa overlap. Previously FT sequenced as SW:GYRA_MYCLE (Q57532) (1273 aa); Fasta score FT E(): 0, 99.9% identity in 1246 aa overlap. Contains a FT probable intein from aa 131 to 550 inclusive. Contains 2 FT Pfam matches to entry PF00521 DNA_topoisoIV, DNA FT gyrase/topoisomerase IV, subunit A. Contains PS00018 FT EF-hand calcium-binding domain. Contains PS00881 Protein FT splicing signature." FT /db_xref="GOA:Q57532" FT /db_xref="HSSP:1AM2" FT /db_xref="InterPro:IPR013757" FT /db_xref="UniProtKB/Swiss-Prot:Q57532" FT /func_characterised="similar sequence" FT /protein_id="CAC29514.1" FT /translation="MTDITLPPGDGSIQRVEPVDIQQEMQRSYIDYAMSVIVGRALPEV FT RDGLKPVHRRVLYAMLDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPW FT SLRYPLVDGQGNFGSPGNDPPAAMRYCVSGNSLVRLLFGKSIRIGDIVTGAQFNSDNPI FT DLKVLDRHGNPVVADYLFHSGEHQTYTVRTTEGYEITGTSNHPLLCLVNVGGIPTLLWK FT LIGEIRSGDYVVLQRIPPVEFGPADWYSTMEALLFGAFISGGFVFQDHAGFNSLDRDYF FT TMVVNAYDTVVGGLRCISSRITVSGSTLLELDVYNLIEFKKTRLSGLCGQRSADKLVPD FT WLWHSPSTVKRAFLQALFEGEGFSSILSRNIIEISYSTLSERLAADVQQMLLEFGVVSE FT RYCHTVNEYKVVIANRAQVEMFFTQVGFGVTKQAKLIRDVVSMSPCVGMDINCVPGLAT FT FIRKHCDNRWVEEDSFNQHNVDCVQHWHHHSAEIVGHIADPDIRAIVTDLTDGRFYYAR FT VASVTDTGIQPVFSLHVDTEDHSFLTNGFISHNTEARLTPLAMEMLREIDEETVDFISN FT YDGRVQEPMVLPSRFPNLLANGSGGIAVGMATNIPPHNLYELADAVFWCLENHDADEET FT MLVAVMERVKGPDFPTAGLIVGSQGIADAYKTGRGSIRIRGVVEVEEDSRGRTSLVITE FT LPYQVNHDNFITSIAEQVRTGRLAGISNVEDQGSDRVGVRIVIEIKRDAVAKVVLNNLY FT KHTQLQTSFGANMLSIVDGVPRTLRLDQMICYYVEHQLDVIVRRTTYRLRKANERAHIL FT RGLVKALDALDEVITLIRASQTVDIARVGVVELLDIDDIQAQAILDMQLRRLAALERQR FT IIDDLAKIEVEIADLGDILAKPERRRGIIRNELTEIAEKYGDDRRTRIIAVDGDVNDED FT LIAREEVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVRHFFVCSTHDWIL FT FFTTQGRVYRAKAYELPEASRTARGQHVANLLAFQPEERIAQVIQIRSYEDAPYLVLAT FT RAGLVKKSKLTDFDSNRSGGIVAINLRDNDELVGAVLCAADGDLLLVSANGQSIRFSAT FT DEALRPMGRATSGVQGMRFNADDRLLSLNVVREDTYLLVATSGGYAKRTSIEEYPMQGR FT GGKGVLTVMYDRRRGSLVGAIVVDEDSELYAITSGGGVIRTTARQVRQAGRQTKGVRLM FT NLGEGDTLLAIARNAEESADGGVG" XX SQ Sequence 3750 BP; 826 A; 882 C; 1075 G; 967 T; 0 other; 2674112791 CRC32; atgactgata tcacgctgcc accaggtgac ggttctatac agcgggttga gccggtcgac 60 attcagcagg aaatgcagcg cagctatatt gattacgcga tgagtgtgat tgtgggccgg 120 gcgttgcctg aagtccgcga tggtctcaaa ccggtacatc gtcgggtctt gtacgcgatg 180 ttagactccg gtttccgccc ggaccgtagc cacgctaagt cagcacggtc agtcgctgag 240 acgatgggca attaccatcc gcacggcgac gcatcgattt atgacacgtt agtgcgcatg 300 gcgcagccgt ggtcgctgcg gtatcccttg gttgatgggc aaggcaattt cggttcgccg 360 ggtaatgacc caccggcagc gatgcgttat tgtgtgtcag gaaattcctt ggtgaggttg 420 ctatttggga aatcaatacg aatcggtgat atcgttactg gagctcagtt caattcggac 480 aatccgatcg acttgaaggt tcttgatcgg catggtaatc cggttgtagc cgattattta 540 ttccattcag gagagcacca aacctataca gtgcgcacca ctgaaggcta tgagatcacc 600 gggacgtcga accatccctt gttgtgttta gtgaatgtcg gcggtatacc caccttgttg 660 tggaagctga ttggagaaat tcgatcagga gactacgttg ttttacagcg gatcccacca 720 gtggaatttg gtccggcgga ctggtattct acgatggaag cattgttatt cggagccttt 780 attagtgggg gcttcgtttt tcaggaccat gctggattta acagccttga ccgtgactat 840 ttcaccatgg ttgttaatgc ttatgatacg gttgtgggtg gcctgcgttg catatcttct 900 cgaatcaccg tatcggggtc gacgctactc gaacttgatg tttataacct catcgagttt 960 aagaagacaa gacttagcgg tttatgcggg caacggtctg cggacaagtt ggtacctgac 1020 tggttgtggc actcaccttc caccgtcaaa cgagcattcc ttcaggcatt gtttgaaggt 1080 gaaggatttt cttcgatatt gtcgcgaaat ataattgaga tttcctactc gacacttagt 1140 gagcgactgg ccgccgacgt ccagcagatg ctgcttgaat tcggagtcgt gtctgagcgc 1200 tattgccata ctgtcaatga gtacaaggtt gtcatagcta accgcgctca agtagaaatg 1260 tttttcaccc aagtcggttt cggtgttact aaacaagcta agcttatccg ggacgtggta 1320 tctatgtctc catgcgttgg catggatatc aactgcgtac caggtttggc cactttcatt 1380 cgtaagcatt gtgataaccg ctgggtcgag gaagactcat ttaatcagca taatgttgat 1440 tgcgtccaac attggcacca tcatagcgcg gaaatcgtcg gccacatcgc cgatcccgat 1500 attcgtgcca tcgtgactga ccttactgat ggccggttct actacgcgcg cgtcgcgtcc 1560 gtgactgata ccggtattca acctgtgttc agtctacatg tggacaccga ggatcattcg 1620 tttttgacta atggattcat cagccataac accgaggctc ggcttactcc attggcgatg 1680 gaaatgttgc gcgagatcga cgaggagaca gttgatttca tatctaacta cgatggccgg 1740 gtgcaggaac cgatggtgtt gcctagccgt tttcccaacc tgttggctaa tggttctggc 1800 ggtatcgcgg tcggcatggc taccaatatc ccgccgcaca acctgtatga gctcgccgac 1860 gctgtgtttt ggtgcctaga gaaccatgac gctgacgaag agacgatgct ggtcgctgtt 1920 atggaacggg tcaaaggtcc tgatttccct accgccgggt tgattgtcgg ttcgcaaggc 1980 attgccgatg cttacaagac tggccgtggt tccattcgga tacgcggagt tgttgaggtt 2040 gaagaagatt cacgcggaag gacgtcattg gtcatcactg agctaccgta tcaggtcaac 2100 cacgacaact tcatcacttc tatcgctgag caagtccgca ctggccggct agccggcatc 2160 tccaatgtag aagaccaagg cagcgaccgg gttggtgtac gtatcgtcat cgagatcaag 2220 cgtgacgcgg tggccaaagt ggtgctcaat aacctgtaca agcatactca gctgcaaact 2280 agtttcggag ccaacatgtt gtcaatcgtt gacggcgtgc cgcgcacttt gcggttggat 2340 cagatgattt gttattatgt cgaacatcaa ctggacgtca ttgtccggcg cactacctac 2400 cgattgcgta aagccaacga gcgggctcat attttgcgtg gattggtcaa agcgctcgat 2460 gcgttagatg aggttattac gttgattcgg gcatcgcaga ccgtggatat tgctcgtgtt 2520 ggggtggtcg agttactcga tatcgacgac attcaggctc aagctatcct ggacatgcag 2580 ctgcggcgtt tggcggcttt ggagcgtcaa cgcattattg atgatctcgc taagattgag 2640 gtcgagatcg ctgatctggg agatattctg gctaagccgg agcgtcggcg tggtatcatt 2700 cgtaatgaac tgactgagat cgcagagaag tacggtgatg accgtcgtac tcggataata 2760 gcggttgatg gtgatgtcaa cgacgaggat ttgattgctc gtgaagaggt cgttgtcacg 2820 ataactgaaa ctggatatgc taaacgtact aaaactgacc tgtatcgcag ccagaaacgc 2880 ggcgggaaag gtgttcaagg cgccggtttg aagcaggacg acatcgtccg gcatttcttc 2940 gtgtgttcaa ctcacgattg gatcctgttt ttcaccaccc aaggccgcgt ataccgggcc 3000 aaggcctatg aattgccaga ggcttctcga acggcacgcg ggcaacacgt ggccaatttg 3060 cttgcattcc agcctgaaga gcgcatcgct caggtaattc agatccgtag ctatgaagac 3120 gctccatact tggtccttgc cacgcgcgcc ggtctggtta agaagtcaaa gttgaccgat 3180 tttgactcta atcgttcggg tgggatcgtg gcaattaatt tacgtgacaa cgatgagttg 3240 gtcggtgcag tgttgtgcgc ggccgacggc gacttgcttc tggtatcggc taacggccag 3300 tctatccggt tctcagcgac tgacgaggcc ttgcgtccga tggggcgggc tacctctggt 3360 gtgcagggca tgcggtttaa cgccgatgat cgactgttgt cgttgaatgt ggttcgcgaa 3420 gatacttacc tgcttgtcgc aacgtctggg ggttacgcta aacgcacctc gattgaggag 3480 tacccgatgc agggccgtgg cggaaagggt gttctaacgg tcatgtacga tcgtcggcgc 3540 ggtagcttgg ttggggccat cgtggttgat gaagacagcg agttgtacgc gatcacctca 3600 gggggtgggg taattcgtac aacggcacgc caggttcgcc aggcaggacg ccagaccaag 3660 ggtgttcggt tgatgaactt aggtgagggc gacacgctgt tagccatcgc acgtaatgcc 3720 gaagaaagcg ccgacggcgg tgtcggttaa 3750 // |
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