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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAB09261; SV 1; linear; genomic DNA; STD; PRO; 744 BP.
XX
PA   BX842576.1
XX
DE   Mycobacterium tuberculosis H37Rv PROBABLE 6-PHOSPHOGLUCONOLACTONASE DEVB
DE   (6PGL)
XX
OS   Mycobacterium tuberculosis H37Rv
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..744
FT                   /organism="Mycobacterium tuberculosis H37Rv"
FT                   /strain="H37Rv"
FT                   /mol_type="genomic DNA"
FT   CDS             complement(BX842576.1:240671..241414)
FT                   /transl_table=11
FT                   /gene="devB"
FT                   /locus_tag="Rv1445c"
FT                   /product="PROBABLE 6-PHOSPHOGLUCONOLACTONASE DEVB (6PGL)"
FT                   /function="INVOLVED IN PENTOSE PHOSPHATE PATHWAY.
FT                   HYDROLYSIS OF 6-PHOSPHOGLUCONOLACTONE TO 6-
FT                   PHOSPHOGLUCONATE. [CATALYTIC ACTIVITY :
FT                   6-PHOSPHO-D-GLUCONO-1,5-LACTONE + H(2)O = 6-
FT                   PHOSPHO-D-GLUCONATE]"
FT                   /EC_number="3.1.1.31"
FT                   /note="Rv1445c, (MTCY493.09), len: 247 aa. Possible devB
FT                   (PGL), 6-phosphogluconolactonase (EC 3.1.1.31), belongs to
FT                   a different family to the upstream gene zwf2. Similar to
FT                   e.g. DEVB_ANASP|P46016 putative glucose-6-phosphate
FT                   1-dehydrogenase (239 aa), FASTA scores: opt: 439, E():
FT                   2.6e-20, (34.0% identity in 247 aa overlap). BELONGS TO THE
FT                   GLUCOSAMINE/GALACTOSAMINE-6-PHOSPHATE ISOMERASE FAMILY.
FT                   6-PHOSPHOGLUCONOLACTONASE SUBFAMILY."
FT                   /db_xref="GOA:P63338"
FT                   /db_xref="InterPro:IPR006148"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63338"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAB09261.1"
FT                   /translation="MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGN
FT                   GIALLRYLSAQAQQIEWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPSNQVHP
FT                   MAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSPAV
FT                   LESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSV
FT                   PAAGAVGRQNTLWLLDRDAAAKLPS"
XX
SQ   Sequence 744 BP; 119 A; 250 C; 255 G; 120 T; 0 other; 3706367728 CRC32;
     gtgagcagta gcatcgagat cttccccgat agcgacattc tggtcgcggc cgcgggtaag        60
     cgcttggttg gcgccatcgg ggccgcggtg gcggccagag ggcaggcgct gatcgtgctg       120
     accgggggcg gcaacgggat tgcgcttctg cgctacctca gcgcccaagc acagcagatt       180
     gaatggtcca aggtgcacct gttctggggc gacgaacgct acgttcccga agacgatgac       240
     gagcgcaatc tcaagcaggc ccggcgggcg ttgctcaatc acgtcgacat tccatcgaac       300
     caggtgcacc cgatggccgc cagtgatggt gacttcggcg gcgatctgga cgccgcggcc       360
     ctggcctacg aacaggtgct ggccgccagt gccgcaccag gtgacccggc gccgaatttc       420
     gacgtccacc tgctgggcat ggggcccgag ggccacatta actcgctgtt cccgcacagc       480
     cccgccgtcc tcgagagcac ccgcatggtg gtggcggtcg acgactcgcc gaaaccgccg       540
     ccacgccgaa tcaccttgac cctgccggcg attcagcgtt cccgcgaggt gtggctgctg       600
     gtttccgggc cgggtaaggc cgacgccgtg gccgcggcca tcggcggcgc cgatccggtt       660
     tcggtaccgg cggccggggc cgtcgggcgt cagaacacgc tctggctgct ggaccgcgac       720
     gccgccgcca agcttccgag ttaa                                              744
//
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