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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAB09259; SV 1; linear; genomic DNA; STD; PRO; 1545 BP.
XX
PA   BX842576.1
XX
DE   Mycobacterium tuberculosis H37Rv PROBABLE GLUCOSE-6-PHOSPHATE
DE   1-DEHYDROGENASE ZWF2 (G6PD)
XX
OS   Mycobacterium tuberculosis H37Rv
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1545
FT                   /organism="Mycobacterium tuberculosis H37Rv"
FT                   /strain="H37Rv"
FT                   /mol_type="genomic DNA"
FT   CDS             complement(BX842576.1:242375..243919)
FT                   /transl_table=11
FT                   /gene="zwf2"
FT                   /locus_tag="Rv1447c"
FT                   /product="PROBABLE GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE ZWF2
FT                   (G6PD)"
FT                   /function="INVOLVED IN PENTOSE PHOSPHATE PATHWAY [CATALYTIC
FT                   ACTIVITY : D-GLUCOSE 6-PHOSPHATE + NADP(+) = D-GLUCONO-
FT                   1,5-LACTONE 6-PHOSPHATE + NADPH]"
FT                   /EC_number="1.1.1.49"
FT                   /note="Rv1447c, (MTCY493.07), len: 514 aa. Probable zwf2
FT                   (ZWF), Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49),
FT                   highly similar to many e.g. G6PD_SYNY3|P73411 Synechocystis
FT                   sp. (509 aa), FASTA scores: opt: 1578, E(): 0, (46.8%
FT                   identity in 509 aa overlap). Also similar to M.
FT                   tuberculosis Rv1121, zwf glucose-6-phosphate
FT                   1-dehydrogenase. Contains PS00069 Glucose-6-phosphate
FT                   dehydrogenase active site. Mycobacterium tuberculosis has
FT                   two genes for ZWF. This one looks like a classical ZWF.
FT                   BELONGS TO THE GLUCOSE-6-PHOSPHATE DEHYDROGENASE FAMILY."
FT                   /db_xref="GOA:P0A584"
FT                   /db_xref="HSSP:1QKI"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A584"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAB09259.1"
FT                   /translation="MKPAHAAASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGDLARKKV
FT                   MPAVYDLANRGLLPPTFSLVGFARRDWSTQDFGQVVYNAVQEHCRTPFRQQNWDRLAEG
FT                   FRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHAFYLAIPPKSFPVVCEQLHKSGLAR
FT                   PQGDRWSRVVIEKPFGHDLASARELNKAVNAVFPEEAVFRIDHYLGKETVQNILALRFA
FT                   NQLFDPIWNAHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEP
FT                   VSFHPAALQAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDSTT
FT                   ETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDATMTDELGTNA
FT                   MVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFAEDSPEAYERLILDVLLGEP
FT                   SLFPVNAEVELAWEILDPALEHWAAHGTPDAYEAGTWGPESSLEMLRRTGREWRRP"
XX
SQ   Sequence 1545 BP; 287 A; 514 C; 504 G; 240 T; 0 other; 794788400 CRC32;
     atgaaaccgg cccacgccgc ggcgtcgtgg cgcaacccgc tacgagacaa gcgggacaag        60
     cgattaccca gaatcgccgg cccgtgcggc atggtgattt tcggcgtcac cggcgacctg       120
     gcccgcaaga aggtgatgcc ggccgtctac gatttggcca accgcggcct gctgccgccc       180
     acattctcgc tggtggggtt tgcccgccga gactggagca cccaggattt cggtcaagtg       240
     gtgtacaacg ccgtccaaga gcactgccga acaccgtttc ggcaacagaa ctgggaccgg       300
     ctggccgagg gattccgttt tgtgccaggc actttcgacg acgacgacgc gttcgcccaa       360
     ctcgccgaga cgctggagaa gctcgacgcc gagcgcggca ccggcggcaa ccacgccttc       420
     tacctggcga tcccgcccaa atccttcccg gtggtgtgtg agcagctgca caagtccggc       480
     ctggcccgcc cgcaaggcga ccggtggagc cgagtcgtga tagagaagcc gttcggccac       540
     gacctggcca gcgcacgcga gctgaacaag gcggtcaacg cggtcttccc ggaggaagcg       600
     gtcttccgca tcgaccacta cctgggcaaa gagacggtgc agaacatcct ggcgctgcgg       660
     ttcgccaacc agctgttcga cccgatctgg aatgcgcact acgtcgacca cgtacagatc       720
     accatggccg aagacatcgg cctgggcggg cgcgcgggct attacgacgg catcggcgcg       780
     gcccgcgatg tcatccagaa ccatctcatg cagctgctgg cgctgaccgc gatggaggag       840
     ccggtcagct tccacccggc agcgttgcag gccgagaaga tcaaggtgct ctcggccacc       900
     cgccttgccg agccactcga ccagaccacc agccgcggcc agtacgccgc cggctggcaa       960
     ggcggggaga aggtggttgg gctgctcgac gaggaggggt tcgccgagga ctccaccacc      1020
     gaaaccttcg ccgctatcac cctggaagtc gatacgcgcc ggtgggccgg cgtgccgttc      1080
     tatctgcgaa cgggaaaacg attgggccgc cgggtgaccg agatcgctct ggtcttcagg      1140
     cgggcgccgc atctgccgtt cgacgccacc atgaccgacg agctgggcac caacgcgatg      1200
     gtcatccgcg tgcagcccga cgaaggtgtc acattgcggt tcggctccaa ggtgccgggc      1260
     accgccatgg aagtccgcga cgtcaacatg gacttctcct acggctcggc attcgccgaa      1320
     gattcaccgg aggcctacga gcggctcatc ctcgacgtcc tgctcggcga gccctcgctg      1380
     tttccggtca acgcggaggt cgaactggcg tgggagatcc tcgatccagc gttggaacat      1440
     tgggcggcac acgggacgcc cgacgcctac gaggcaggta cctggggtcc ggaatcatcc      1500
     ttggagatgc tgcgccgcac cggccgggaa tggcggcggc catag                      1545
//
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