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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAB01254; SV 1; linear; genomic DNA; STD; PRO; 1350 BP.
XX
PA   BX842580.1
XX
DE   Mycobacterium tuberculosis H37Rv 4-AMINOBUTYRATE AMINOTRANSFERASE GABT
DE   (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE)
DE   (GLUTAMATE:SUCCINIC SEMIALDEHYDE TRANSAMINASE) (GABA AMINOTRANSFERASE)
DE   (GABA-AT)
XX
OS   Mycobacterium tuberculosis H37Rv
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1350
FT                   /organism="Mycobacterium tuberculosis H37Rv"
FT                   /strain="H37Rv"
FT                   /mol_type="genomic DNA"
FT   CDS             BX842580.1:143324..144673
FT                   /transl_table=11
FT                   /gene="gabT"
FT                   /locus_tag="Rv2589"
FT                   /product="4-AMINOBUTYRATE AMINOTRANSFERASE GABT
FT                   (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE)
FT                   (GLUTAMATE:SUCCINIC SEMIALDEHYDE TRANSAMINASE) (GABA
FT                   AMINOTRANSFERASE) (GABA-AT)"
FT                   /function="INVOLVED IN 4-AMINOBUTYRATE (GABA) DEGRADATION
FT                   PATHWAY [CATALYTIC ACTIVITY: 4-AMINOBUTANOATE +
FT                   2-OXOGLUTARATE = SUCCINATE SEMIALDEHYDE + L-GLUTAMATE]."
FT                   /EC_number="2.6.1.9"
FT                   /note="Rv2589, (MTCY227.12c), len: 449 aa. Probable gabT,
FT                   4-aminobutyrate aminotransferase (EC 2.6.1.9), equivalent
FT                   to P40829|GABT_MYCLE|ML0485|MLCB1259.03c|B1177_F2_67
FT                   4-AMINOBUTYRATE AMINOTRANSFERASE (446 aa), FASTA scores:
FT                   opt: 2468, E(): 4.5e-141, (83.75% identity in 449 aa
FT                   overlap). Also highly similar to others e.g. O86823|GABT
FT                   from Streptomyces coelicolor (444 aa), FASTA scores: opt:
FT                   1832, E(): 8e-103, (63.9% identity in 443 aa overlap);
FT                   AAK79395|CAC1427 from Clostridium acetobutylicum (445 aa),
FT                   FASTA scores: opt: 1283, E(): 8.4e-70, (45.75% identity in
FT                   433 aa overlap); Q9KE66|BH0991 from Bacillus halodurans
FT                   (443 aa), FASTA scores: opt: 1224, E(): 2.9e-66, (44.55%
FT                   identity in 431 aa overlap); etc. Contains PS00600
FT                   Aminotransferases class-III pyridoxal-phosphate attachment
FT                   site. BELONGS TO CLASS-III OF PYRIDOXAL-PHOSPHATE-DEPENDENT
FT                   AMINOTRANSFERASES. COFACTOR: PYRIDOXAL PHOSPHATE."
FT                   /db_xref="GOA:P63504"
FT                   /db_xref="HSSP:1QJ3"
FT                   /db_xref="InterPro:IPR015421"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63504"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAB01254.1"
FT                   /translation="MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARA
FT                   GGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVTPYEGYVAV
FT                   AEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGKPAVVAFDHAYHGRTNLTMAL
FT                   TAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLDKQLATNGELAAARAIGVIDKQVGANN
FT                   LAALVIEPIQGEGGFIVPAEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEG
FT                   PDGLEPDLICTAKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIAT
FT                   IESDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTEPDAGLTE
FT                   RLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIVCAILADL"
XX
SQ   Sequence 1350 BP; 230 A; 460 C; 444 G; 216 T; 0 other; 320335369 CRC32;
     gtggccagcc tgcagcagag tcggcgcctg gtcaccgaaa tccccggtcc cgcatcgcag        60
     gcactgactc accgccgggc ggcggcggtg tccagcggtg ttggggtcac cctgccggtg       120
     ttcgtagccc gcgccggcgg cggcatcgtg gaagacgtgg acggtaaccg gctcatcgac       180
     ctgggttcgg gcatcgcagt gacgacgatc ggcaactcgt cgccacgcgt ggtggatgcg       240
     gtgcgcacgc aggtggccga atttacccac acctgcttca tggtgacgcc atacgagggg       300
     tacgtggccg tcgccgagca actcaaccgg attaccccag gttcgggccc caagcgctcg       360
     gtgttgttca attccggcgc cgaggcagtc gagaacgccg tcaagatcgc acgctcctac       420
     accggcaagc ccgcggtggt ggcgttcgac cacgcctacc acggtcgcac caacctaacg       480
     atggcgctga ccgccaagtc gatgccctac aagagcggct tcggtccgtt cgcgccggag       540
     atctaccgag cgccattgtc ttacccctat cgggacggcc tcctcgataa gcaactggct       600
     accaatggtg agctagccgc ggcccgagcc atcggcgtca tcgacaagca ggtaggcgcg       660
     aacaacctgg ccgccctcgt catcgaaccg atccagggcg aaggcggttt catcgttccg       720
     gccgaagggt tcctacctgc cctcctcgat tggtgccgca agaaccatgt ggtgttcatc       780
     gccgacgagg tgcaaaccgg ctttgcccgt accggggcga tgttcgcctg cgagcacgag       840
     ggccccgacg gtctagagcc cgacctgatc tgcacggcca aaggcatcgc cgatggattg       900
     ccgctgtcgg cggtcaccgg ccgcgccgag atcatgaacg ccccgcacgt gggcggcctg       960
     ggcggcacgt tcggcggcaa cccggtggcc tgtgcggccg cgctggccac catcgcaacc      1020
     atcgaaagcg acgggctgat cgagcgggcc cgccagatcg aacgcctggt gaccgaccgg      1080
     ttgacgacgc tgcaggccgt cgacgaccgg atcggcgacg tgcgtggtcg cggcgccatg      1140
     atcgccgtag agctggtcaa atccggaacc accgagcccg acgccgggct gaccgagcgg      1200
     ctggcgaccg cggcccacgc cgccggcgtc atcattttga cctgcggcat gttcggcaac      1260
     atcatccggc tactgccgcc gctgaccatc ggcgacgagc tgctgagtga ggggctggac      1320
     atcgtgtgcg cgatcttggc cgacctctga                                       1350
//
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