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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAB00926; SV 1; linear; genomic DNA; STD; PRO; 888 BP.
XX
PA   BX842573.1
XX
DE   Mycobacterium tuberculosis H37Rv PROBABLE PYRROLINE-5-CARBOXYLATE REDUCTASE
DE   PROC (P5CR) (P5C REDUCTASE)
XX
OS   Mycobacterium tuberculosis H37Rv
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..888
FT                   /organism="Mycobacterium tuberculosis H37Rv"
FT                   /strain="H37Rv"
FT                   /mol_type="genomic DNA"
FT   CDS             BX842573.1:248176..249063
FT                   /transl_table=11
FT                   /gene="proC"
FT                   /locus_tag="Rv0500"
FT                   /product="PROBABLE PYRROLINE-5-CARBOXYLATE REDUCTASE PROC
FT                   (P5CR) (P5C REDUCTASE)"
FT                   /function="INVOLVED AT THE TERMINAL (THIRD) STEP IN PROLINE
FT                   BIOSYNTHESIS [CATALYTIC ACTIVITY: L-proline + NAD(P)+ =
FT                   1-pyrroline-5-carboxylate + NAD(P)H]."
FT                   /EC_number="1.5.1.2"
FT                   /note="Rv0500, (MTCY20G9.26), len: 295 aa. Probable proC,
FT                   Pyrroline-5-carboxylate reductase (EC 1.5.1.2) (see
FT                   citation below), equivalent to P46725|PROC_MYCLE
FT                   PYRROLINE-5-CARBOXYLATE REDUCTASE from Mycobacterium leprae
FT                   (294 aa), FASTA scores: opt: 1473, E(): 0, (82.4% identity
FT                   in 295 aa overlap). Also similar to others e.g.
FT                   P46540|PROC_CORGL PYRROLINE-5-CARBOXYLATE REDUCTASE from
FT                   Corynebacterium glutamicum (270 aa);
FT                   T36286|4803683|CAB42663.1|AL049819 pyrroline-5-carboxylate
FT                   reductase from Streptomyces coelicolor (284 aa); etc.
FT                   BELONGS TO THE PYRROLINE-5-CARBOXYLATE REDUCTASE FAMILY."
FT                   /db_xref="GOA:Q11141"
FT                   /db_xref="InterPro:IPR000304"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q11141"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAB00926.1"
FT                   /translation="MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRAN
FT                   YLAQTYSVLVTSAADAVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVV
FT                   AGITIAYFESKLPAGTPVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGG
FT                   VLTVPESQLDAVTAVSGSGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAML
FT                   LERMEQDQGGANGELMGLRVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQ
FT                   AAKSRSEQLRITPE"
XX
SQ   Sequence 888 BP; 141 A; 255 C; 333 G; 159 T; 0 other; 1464629367 CRC32;
     atgcttttcg gcatggcaag gatcgcgatt atcggcggcg gcagcatcgg tgaggcattg        60
     ctgtcgggtc tgctgcgggc gggccggcag gtcaaagacc tggtagtggc cgagcggatg       120
     cccgatcgcg ccaactacct ggcgcagacc tattcggtgt tggtgacgtc ggcggccgac       180
     gcggtggaga acgcgacgtt cgtcgtcgtc gcggtcaaac cagccgacgt cgagccggtg       240
     atcgcggatc tggcgaacgc gactgcggcg gccgaaaacg acagtgctga gcaggtgttc       300
     gtcaccgtgg tagcgggcat cacgatcgcg tatttcgaat ccaagctacc ggctgggacg       360
     ccagtggtgc gtgcgatgcc gaacgcggcg gcattggtgg gagcgggggt tacagcgctg       420
     gccaaaggcc gctttgtcac cccgcaacag cttgaggagg tctcggcctt gttcgacgcg       480
     gtcggcggcg tgctgaccgt tccggaatcg cagttggacg cggtgaccgc ggtgtccggc       540
     tcgggtccgg cctatttctt tctgctggtc gaggccctgg tggatgccgg agtcggggtg       600
     ggcttgagcc gtcaggtggc caccgatctc gccgcgcaga caatggctgg ctcagcggcg       660
     atgctgctgg agcggatgga gcaagaccag ggtggcgcca atggcgagct gatggggctg       720
     cgcgtggacc ttaccgcatc acggctgcgc gccgcggtta cctcgccggg cggtacgacc       780
     gccgctgcgc tgcgggaact cgaacgcggc gggtttcgga tggctgtcga cgcggcggtt       840
     caagccgcca aaagccgctc tgagcagctc agaattacac cggaatga                    888
//
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