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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAA98311; SV 1; linear; genomic DNA; STD; PRO; 1752 BP.
XX
PA   BX842577.1
XX
DE   Mycobacterium tuberculosis H37Rv PROBABLE FUMARATE REDUCTASE [FLAVOPROTEIN
DE   SUBUNIT] FRDA (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)
XX
OS   Mycobacterium tuberculosis H37Rv
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1752
FT                   /organism="Mycobacterium tuberculosis H37Rv"
FT                   /strain="H37Rv"
FT                   /mol_type="genomic DNA"
FT   CDS             BX842577.1:26424..28175
FT                   /transl_table=11
FT                   /gene="frdA"
FT                   /locus_tag="Rv1552"
FT                   /product="PROBABLE FUMARATE REDUCTASE [FLAVOPROTEIN
FT                   SUBUNIT] FRDA (FUMARATE DEHYDROGENASE) (FUMARIC
FT                   HYDROGENASE)"
FT                   /function="INVOLVED IN INTERCONVERSION OF FUMARATE AND
FT                   SUCCINATE (ANAEROBIC RESPIRATION) [CATALYTIC ACTIVITY :
FT                   SUCCINATE + ACCEPTOR = FUMARATE + REDUCED ACCEPTOR]."
FT                   /EC_number="1.3.99.1"
FT                   /note="Rv1552, (MTCY48.13c), len: 583 aa. Probable frdA,
FT                   fumarate reductase, flavoprotein subunit (EC 1.3.99.1),
FT                   highly similar to others e.g. P00363|FRDA_ECOLI fumarate
FT                   reductase flavoprotein subunit from Escherichia coli strain
FT                   K12 (601 aa), FASTA scores: opt: 2102, E(): 0, (54.7%
FT                   identity in 585 aa overlap); NP_232284.1|NC_002505 fumarate
FT                   reductase, flavoprotein subunit from Vibrio cholerae (602
FT                   aa); frdA|NP_438995.1|NC_000907 fumarate reductase,
FT                   flavoprotein subunit from Haemophilus influenzae (599 aa);
FT                   etc. Contains PS00504 Fumarate reductase / succinate
FT                   dehydrogenase FAD-binding site. NOTE THAT FUMARATE
FT                   REDUCTASE FORMS PART OF AN ENZYME COMPLEX CONTAINING FOUR
FT                   SUBUNITS: A FLAVOPROTEIN (Rv1552|frdA), AN IRON-SULFUR
FT                   (Rv1553|frdB), AND TWO HYDROPHOBIC ANCHOR PROTEINS
FT                   (Rv1554|frdC and Rv1555|frdD)."
FT                   /db_xref="GOA:P64174"
FT                   /db_xref="HSSP:1KF6"
FT                   /db_xref="InterPro:IPR014006"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64174"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAA98311.1"
FT                   /translation="MTAQHNIVVIGGGGAGLRAAIAIAETNPHLDVAIVSKVYPMRSHT
FT                   VSAEGGAAAVTGDDDSLDEHAHDTVSGGDWLCDQDAVEAFVAEAPKELVQLEHWGCPWS
FT                   RKPDGRVAVRPFGGMKKLRTWFAADKTGFHLLHTLFQRLLTYSDVMRYDEWFATTLLVD
FT                   DGRVCGLVAIELATGRIETILADAVILCTGGCGRVFPFTTNANIKTGDGMALAFRAGAP
FT                   LKDMEFVQYHPTGLPFTGILITEAARAEGGWLLNKDGYRYLQDYDLGKPTPEPRLRSME
FT                   LGPRDRLSQAFVHEHNKGRTVDTPYGPVVYLDLRHLGADLIDAKLPFVRELCRDYQHID
FT                   PVVELVPVRPVVHYMMGGVHTDINGATTLPGLYAAGETACVSINGANRLGSNSLPELLV
FT                   FGARAGRAAADYAARHQKSDRGPSSAVRAQARTEALRLERELSRHGQGGERIADIRADM
FT                   QATLESAAGIYRDGPTLTKAVEEIRVLQERFATAGIDDHSRTFNTELTALLELSGMLDV
FT                   ALAIVESGLRREESRGAHQRTDFPNRDDEHFLAHTLVHRESDGTLRVGYLPVTITRWPP
FT                   GERVYGR"
XX
SQ   Sequence 1752 BP; 340 A; 546 C; 565 G; 301 T; 0 other; 535432209 CRC32;
     atgaccgccc aacacaacat cgtggttatc ggcggcggtg gtgcgggtct gcgcgccgcg        60
     attgcgatag ccgaaaccaa tccgcacctg gatgtggcga tcgtttccaa ggtgtacccg       120
     atgcgcagcc acaccgtctc ggctgagggc ggcgccgcgg cggtgaccgg tgacgacgac       180
     agcctcgatg aacacgcgca cgacacggta tccggtggcg actggctgtg tgaccaagat       240
     gcggtcgagg ctttcgtggc cgaggcgccc aaagagttgg tgcagctcga gcattggggc       300
     tgtccgtgga gccgtaaacc agacgggcgc gttgccgttc gcccgttcgg cgggatgaag       360
     aagctgcgca cctggtttgc cgccgacaag acgggatttc acctcctgca cacgttgttt       420
     caacggctgc tcacctattc cgacgtcatg cgctatgacg agtggttcgc tacgacgctg       480
     ctggtcgacg acggcagggt atgtggtctg gtcgctatcg agttggcgac cgggcgcatc       540
     gagacgatcc ttgccgacgc ggtgattctg tgcaccggcg gatgcgggcg ggtatttcca       600
     ttcaccacca acgcgaacat caagaccggc gacggcatgg cgctcgcatt ccgcgcgggc       660
     gcgcccctaa aagacatgga attcgtccaa taccacccca ccggactgcc gttcaccggg       720
     atcttgatca ccgaggccgc acgagctgaa ggcggctggc tgctcaacaa agacggctac       780
     cgctacctcc aggattacga cctcggcaag cccacgcccg agcccaggct gcgcagtatg       840
     gagctcgggc ccagggaccg actgtcgcag gccttcgtac acgagcacaa caaaggaagg       900
     acggtcgaca ccccgtacgg ccccgtcgtc tatctagacc tgcggcacct gggggcggac       960
     ctgatcgatg caaagttgcc gttcgtacgt gagctgtgcc gcgactacca gcacatcgac      1020
     cccgtggtcg aattggtccc ggtacgaccg gtagtgcact acatgatggg tggcgttcac      1080
     accgatatca acggcgccac aacgcttccc gggctatatg ccgcaggtga aacagcctgc      1140
     gtgagcatta atggcgccaa ccgcctgggg tcgaactcgc tgcccgagct gctggtgttc      1200
     ggggctcgag cgggccgtgc cgccgcggat tacgcagcgc gccaccaaaa gtcggaccgt      1260
     ggcccgtcgt cggcagtgcg ggctcaggcc cgcaccgagg ctctacggct agagcgtgag      1320
     ctcagccgcc atggccaggg aggcgaacga atcgcggata ttcgggcgga catgcaggcc      1380
     accttggaaa gcgccgcggg tatttatcgt gacggaccca ccctcaccaa agcggtcgag      1440
     gagattcggg tgctgcagga acgattcgcc acggcgggca tcgacgatca cagccgcaca      1500
     ttcaacaccg agctgactgc gctgctcgag ttgtcgggga tgctcgacgt tgcactggcg      1560
     atcgtcgaat cgggtttgcg ccgagaagaa tcccgtggcg cacaccagcg aaccgacttt      1620
     ccgaaccggg acgacgagca tttcttggcg cacaccttgg ttcatagaga aagcgacgga      1680
     acgctgcggg tcggctacct tccggtcact atcactcgct ggccaccggg cgaacgcgtg      1740
     tatgggaggt aa                                                          1752
//
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