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EBI DbfetchID CAA94662; SV 1; linear; genomic DNA; STD; PRO; 2706 BP. XX PA BX842579.1 XX DE Mycobacterium tuberculosis H37Rv Probable pyruvate dehydrogenase E1 DE component aceE (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DE DEHYDROGENASE) XX OS Mycobacterium tuberculosis H37Rv OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Corynebacterineae; Mycobacteriaceae; Mycobacterium; OC Mycobacterium tuberculosis complex. OX NCBI_TaxID=83332; XX FH Key Location/Qualifiers FH FT source 1..2706 FT /organism="Mycobacterium tuberculosis H37Rv" FT /strain="H37Rv" FT /mol_type="genomic DNA" FT CDS BX842579.1:87700..90405 FT /transl_table=11 FT /gene="aceE" FT /locus_tag="Rv2241" FT /product="Probable pyruvate dehydrogenase E1 component aceE FT (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC FT DEHYDROGENASE)" FT /function="Involved in energy metabolism; contributes to FT acetyl-CoA production as part of pyruvate dehydrogenase FT complex [CATALYTIC ACTIVITY: PYRUVATE + LIPOAMIDE = FT S-ACETYL-DIHYDRO-LIPOAMIDE + CO(2)]." FT /EC_number="1.2.4.1" FT /note="Rv2241, (MTCY427.22), len: 901 aa. Probable aceE, FT pyruvate dehydrogenase E1 component (EC 1.2.4.1), similar FT to others e.g. ODP1_ECOLI|P06958 pyruvate dehydrogenase E1 FT component from Escherichia coli, FASTA score: (51.2% FT identity in 891 aa overlap); etc." FT /db_xref="GOA:Q10504" FT /db_xref="HSSP:1L8A" FT /db_xref="InterPro:IPR015941" FT /db_xref="UniProtKB/Swiss-Prot:Q10504" FT /experiment="experimental evidence, no additional details FT recorded" FT /func_characterised="identical sequence" FT /protein_id="CAA94662.1" FT /translation="MASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGE FT QRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGG FT HISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDG FT FRQEHSHVGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSD FT QHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELES FT FFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFG FT RDPRTKALVENMSDQDIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGK FT HFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLD FT RRRALGGFVPERRTKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIG FT PRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINE FT AGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGR FT TTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYI FT TVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLA FT AEWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDW FT MRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEID FT PSVPVAAARQYRIDDVAAAPEQTTDPGPGA" XX SQ Sequence 2706 BP; 507 A; 884 C; 867 G; 448 T; 0 other; 3361301097 CRC32; gtggcgtcgt atttgcccga cattgatccc gaggagacct cggagtggct ggagtccttt 60 gacacgctgc tgcaacgctg cggcccgtcg cgggcccgct acctgatgtt gcggctgcta 120 gagcgggccg gcgagcagcg ggtggccatc ccggcattga cgtctaccga ctatgtcaac 180 accatcccga ccgagctgga gccgtggttc cccggcgacg aagacgtcga acgtcgttat 240 cgagcgtgga tcagatggaa tgcggccatc atggtgcacc gtgcgcaacg accgggtgtg 300 ggcgtgggtg gccatatctc gacctacgcg tcgtccgcgg cgctctatga ggtcggtttc 360 aaccacttct tccgcggcaa gtcgcacccg ggcggcggcg atcaggtgtt catccagggc 420 cacgcttccc cgggaatcta cgcgcgcgcc ttcctcgaag ggcggttgac cgccgagcaa 480 ctcgacggat tccgccagga acacagccat gtcggcggcg ggttgccgtc ctatccgcac 540 ccgcggctca tgcccgactt ctgggaattc cccaccgtgt cgatgggttt gggcccgctc 600 aacgccatct accaggcacg gttcaaccac tatctgcatg accgcggtat caaagacacc 660 tccgatcaac acgtgtggtg ttttttgggc gacggcgaga tggacgaacc cgagagccgt 720 gggctggccc acgtcggcgc gctggaaggc ttggacaact tgaccttcgt gatcaactgc 780 aatctgcagc gactcgacgg cccggtgcgc ggcaacggca agatcatcca ggagctggag 840 tcgttcttcc gcggtgccgg ctggaacgtc atcaaggtgg tgtggggccg cgaatgggat 900 gccctgctgc acgccgaccg cgacggtgcg ctggtgaatt taatgaatac aacacccgat 960 ggcgattacc agacctataa ggccaacgac ggcggctacg tgcgtgacca cttcttcggc 1020 cgcgacccac gcaccaaggc gctggtggag aacatgagcg accaggatat ctggaacctc 1080 aaacggggcg gccacgatta ccgcaaggtt tacgccgcct accgcgccgc cgtcgaccac 1140 aagggacagc cgacggtgat cctggccaag accatcaaag gctacgcgct gggcaagcat 1200 ttcgaaggac gcaatgccac ccaccagatg aaaaaactga ccctggaaga ccttaaggag 1260 tttcgtgaca cgcagcggat tccggtcagc gacgcccagc ttgaagagaa tccgtacctg 1320 ccgccctact accaccccgg cctcaacgcc ccggagattc gttacatgct cgaccggcgc 1380 cgggccctcg ggggctttgt tcccgagcgc aggaccaagt ccaaagcgct gaccctgccg 1440 ggtcgcgaca tctacgcgcc gctgaaaaag ggctctgggc accaggaggt ggccaccacc 1500 atggcgacgg tgcgcacgtt caaagaagtg ttgcgcgaca agcagatcgg gccgcggata 1560 gtcccgatca ttcccgacga ggcccgcacc ttcgggatgg actcctggtt cccgtcgcta 1620 aagatctata accgcaatgg ccagctgtat accgcggttg acgccgacct gatgctggcc 1680 tacaaggaga gcgaagtcgg gcagatcctg cacgagggca tcaacgaagc cgggtcggtg 1740 ggctcgttca tcgcggccgg cacctcgtat gcgacgcaca acgaaccgat gatccccatt 1800 tacatcttct actcgatgtt cggcttccag cgcaccggcg atagcttctg ggccgcggcc 1860 gaccagatgg ctcgagggtt cgtgctcggg gccaccgccg ggcgcaccac cctgaccggt 1920 gagggcctgc aacacgccga cggtcactcg ttgctgctgg ccgccaccaa cccggcggtg 1980 gttgcctacg acccggcctt cgcctacgaa atcgcctaca tcgtggaaag cggactggcc 2040 aggatgtgcg gggagaaccc ggagaacatc ttcttctaca tcaccgtcta caacgagccg 2100 tacgtgcagc cgccggagcc ggagaacttc gatcccgagg gcgtgctgcg gggtatctac 2160 cgctatcacg cggccaccga gcaacgcacc aacaaggcgc agatcctggc ctccggggta 2220 gcgatgcccg cggcgctgcg ggcagcacag atgctggccg ccgagtggga tgtcgccgcc 2280 gacgtgtggt cggtgaccag ttggggcgag ctaaaccgcg acggggtggc catcgagacc 2340 gagaagctcc gccaccccga tcggccggcg ggcgtgccct acgtgacgag agcgctggag 2400 aatgctcggg gcccggtgat cgcggtgtcg gactggatgc gcgcggtccc cgagcagatc 2460 cgaccgtggg tgccgggcac atacctcacg ttgggcaccg acgggttcgg cttttccgac 2520 actcggcccg ccgctcgccg ctacttcaac accgacgccg aatcccaggt ggtcgcggtt 2580 ttggaggcgt tggcgggcga cggcgagatc gacccatcgg tgccggtcgc ggccgcccgc 2640 cagtaccgga tcgacgacgt ggcggctgcg cccgagcaga ccacggatcc cggtcccggg 2700 gcctaa 2706 // |
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