spacer
spacer
EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAA16130; SV 1; linear; genomic DNA; STD; PRO; 1041 BP.
XX
PA   BX842581.1
XX
DE   Mycobacterium tuberculosis H37Rv PROBABLE NADP-DEPENDENT ALCOHOL
DE   DEHYDROGENASE ADHC
XX
OS   Mycobacterium tuberculosis H37Rv
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1041
FT                   /organism="Mycobacterium tuberculosis H37Rv"
FT                   /strain="H37Rv"
FT                   /mol_type="genomic DNA"
FT   CDS             BX842581.1:287248..288288
FT                   /transl_table=11
FT                   /gene="adhC"
FT                   /locus_tag="Rv3045"
FT                   /product="PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE
FT                   ADHC"
FT                   /function="GENERATES ALDEHYDE OR KETONE FROM ALCOHOL
FT                   [CATALYTIC ACTIVITY: ALCOHOL + NADP(+) = ALDEHYDE OR KETONE
FT                   + NADPH]."
FT                   /EC_number="1.1.1.2"
FT                   /note="Rv3045, (MTV012.60), len: 346 aa. Probable adhC,
FT                   NADP-dependent alcohol dehydrogenase (EC 1.1.1.2),
FT                   equivalent to Q9CBQ3|ADHA|ML1730 ALCOHOL DEHYDROGENASES
FT                   from Mycobacterium leprae (362 aa), FASTA scores: opt:
FT                   1982, E(): 1.3e-111, (85.85% identity in 346 aa overlap);
FT                   Q9AE96|ADHC from Mycobacterium smegmatis (348 aa), FASTA
FT                   scores: opt: 1808, E(): 3.4e-101, (78.95% identity in 347
FT                   aa overlap); Q9EWF1|SCK13.33c PUTATIVE DEHYDROGENASE from
FT                   Streptomyces coelicolor (346 aa), FASTA scores: opt: 1508,
FT                   E(): 3.3e-83, (64.45% identity in 346 aa overlap);
FT                   O06007|ADHA from Bacillus subtilis (349 aa), FASTA scores:
FT                   opt: 1412, E(): 1.9e-77, (61.8% identity in 335 aa
FT                   overlap); etc. Contains PS00059 Zinc-containing alcohol
FT                   dehydrogenases signature. BELONGS TO THE ZINC-CONTAINING
FT                   ALCOHOL DEHYDROGENASE FAMILY. HIGH SIMILARITY WITH OTHER
FT                   BACTERIAL ADH'S. TBparse score is 0.878."
FT                   /db_xref="GOA:P0A4X0"
FT                   /db_xref="InterPro:IPR002085"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A4X0"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAA16130.1"
FT                   /translation="MSTVAAYAAMSATEPLTKTTITRRDPGPHDVAIDIKFAGICHSDI
FT                   HTVKAEWGQPNYPVVPGHEIAGVVTAVGSEVTKYRQGDRVGVGCFVDSCRECNSCTRGI
FT                   EQYCKPGANFTYNSIGKDGQPTQGGYSEAIVVDENYVLRIPDVLPLDVAAPLLCAGITL
FT                   YSPLRHWNAGANTRVAIIGLGGLGHMGVKLGAAMGADVTVLSQSLKKMEDGLRLGAKSY
FT                   YATADPDTFRKLRGGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAVPAFAL
FT                   ALMRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDAYERVLASDVRYRFV
FT                   IDISAL"
XX
SQ   Sequence 1041 BP; 200 A; 345 C; 328 G; 168 T; 0 other; 1911793662 CRC32;
     atgagcactg ttgccgccta cgccgccatg tcggcgaccg aacccctgac caagaccacg        60
     atcacccgtc gcgacccggg cccgcacgac gtggcgatcg acatcaagtt cgccggaatc       120
     tgtcactcgg acatccatac cgtcaaagcc gagtggggcc aaccgaatta ccctgtggtc       180
     cctggccacg agatcgccgg cgtggtgacc gccgtgggct cggaggtgac caagtaccgg       240
     cagggcgacc gcgttggggt tggctgtttc gtggactcgt gccgcgagtg caacagttgc       300
     acgcgcggca tcgaacagta ctgcaagccg ggcgcaaact tcacctacaa ctcgatcggc       360
     aaagacggcc agccaaccca gggcggctac agcgaagcga tcgtcgtcga cgaaaactac       420
     gtgttgcgca tacccgacgt gctgcccctg gatgtggcgg cgccgctgtt gtgcgcgggc       480
     atcacgctgt actcgccact gcgccactgg aatgccgggg cgaacacgcg ggtggcgatc       540
     atcggcctag gcggactggg tcacatgggc gtcaagctgg gcgccgcgat gggcgccgac       600
     gtgacggtgc tgtcccaatc gctgaagaaa atggaggacg gtctgcgctt gggggccaag       660
     agctactacg cgaccgccga cccggacacc ttccgcaagc tgcgcggcgg cttcgacctg       720
     atcctgaaca ccgtctcggc taacttggac ctcggccagt acctgaacct gctggacgtc       780
     gacggcacac tcgtggaact gggtatcccc gagcacccca tggccgtgcc ggcgttcgcg       840
     ctagcgctca tgcgacgcag cctggccggg tccaacatcg gcgggatcgc cgagacccag       900
     gagatgctca atttctgtgc cgagcacggc gtgacacccg aaatcgagct gattgaaccg       960
     gactacatca acgacgccta cgagcgcgtg ctggccagcg acgtgcgcta ccgcttcgtc      1020
     atcgacatct cagccctgtg a                                                1041
//
spacer
spacer