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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   CAA16000; SV 1; linear; genomic DNA; STD; PRO; 858 BP.
XX
PA   BX842576.1
XX
DE   Mycobacterium tuberculosis H37Rv POSSIBLE ENOYL-CoA HYDRATASE ECHA12 (ENOYL
DE   HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
XX
OS   Mycobacterium tuberculosis H37Rv
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..858
FT                   /organism="Mycobacterium tuberculosis H37Rv"
FT                   /strain="H37Rv"
FT                   /mol_type="genomic DNA"
FT   CDS             BX842576.1:276720..277577
FT                   /transl_table=11
FT                   /gene="echA12"
FT                   /locus_tag="Rv1472"
FT                   /product="POSSIBLE ENOYL-CoA HYDRATASE ECHA12 (ENOYL
FT                   HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)"
FT                   /function="COULD POSSIBLY OXIDIZES FATTY ACIDS USING
FT                   SPECIFIC COMPONENTS (BY SIMILARITY) [CATALYTIC ACTIVITY:
FT                   (3S)-3-HYDROXYACYL-CoA = TRANS-2(OR 3)-ENOYL-CoA + H(2)O]."
FT                   /EC_number="4.2.1.17"
FT                   /note="Rv1472, (MTV007.19), len: 285 aa. Possible echA12,
FT                   enoyl-CoA hydratase (EC 4.2.1.17), highly similar to
FT                   P53526|ECHH_MYCLE|NP_301896.1|NC_002677 possible enoyl-CoA
FT                   hydratase/isomerase from Mycobacterium leprae (294 aa),
FT                   FASTA scores: opt: 1265, E(): 0, (72.0% identity in 271 aa
FT                   overlap). Also similar to others e.g. CAA66096.1|X97452
FT                   enoyl-CoA isomerase from Escherichia coli strain K12 (262
FT                   aa); CAC44593.1|AL596162 putative enoyl-CoA hydratase from
FT                   Streptomyces coelicolor (275 aa); etc. Also similar to
FT                   others from Mycobacterium tuberculosis e.g.
FT                   ECHA16|Rv2831|MTCY16B7.11c (249 aa), FASTA scores: opt:
FT                   232, E(): 1.3e-15, (33.8% identity in 204 aa overlap); etc.
FT                   TBparse score is 0.916."
FT                   /db_xref="GOA:O53163"
FT                   /db_xref="HSSP:1MJ3"
FT                   /db_xref="InterPro:IPR018376"
FT                   /db_xref="UniProtKB/Swiss-Prot:O53163"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="CAA16000.1"
FT                   /translation="MPHRCAAQVVAGYRSTVSLVLVEHPRPEIAQITLNRPERMNSMAF
FT                   DVMVPLKEALAQVSYDNSVRVVVLTGAGRGFSPGADHKSAGVVPHVENLTRPTYALRSM
FT                   ELLDDVILMLRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTAS
FT                   ELGLSYLLPRAIGSSRAFEIMLTGRDVSAEEAERIGLVSRQVPDEQLLDACYAIAARMA
FT                   GFSRPGIELTKRTLWSGLDAASLEAHMQAEGLGQLFVRLLTANFEEAVAARAEQRAPVF
FT                   TDDT"
XX
SQ   Sequence 858 BP; 145 A; 262 C; 295 G; 156 T; 0 other; 3508985452 CRC32;
     gtgccccacc gctgcgcggc gcaagtcgtc gccgggtacc gttcaacggt gagtttggtc        60
     ctcgtcgaac acccgcggcc cgagatcgcg cagattaccc tcaaccggcc ggagcggatg       120
     aactccatgg cattcgatgt catggtgccg ctcaaagagg ccttagcgca ggtcagctac       180
     gacaactcgg tgcgggtggt ggtgctgacc ggcgcgggtc gagggttttc tccgggtgcg       240
     gatcacaagt cggcgggggt ggtgccgcac gtcgagaact tgactcggcc cacctacgcg       300
     ctgcgttcga tggagctcct cgatgacgtc atcttaatgc tgcgacggct gcaccagccg       360
     gtgatcgccg cggtcaacgg ccccgccatc ggtggtgggc tgtgcctggc actggctgca       420
     gacattcggg tggcctcgag tagcgcctac ttccgggccg ccggtatcaa caacgggctg       480
     accgccagcg aattggggct gagctacctg ttgcccaggg ccattggatc ctcacgtgcg       540
     ttcgagatca tgttgaccgg tcgcgacgtc agcgccgagg aagccgagag gatcgggctg       600
     gtatcccgtc aggtacccga tgaacagctg ctagatgcct gctacgcgat cgccgcacgg       660
     atggcgggat tctcgcggcc gggaattgag ttgaccaaac gtacgctgtg gagtggactg       720
     gacgccgcca gtctggaggc gcacatgcag gccgagggct tggggcagct cttcgtccgg       780
     ctgctcaccg ccaacttcga agaagcggtt gccgcacggg ccgagcagcg ggcgccggtg       840
     ttcaccgatg acacgtaa                                                     858
//
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