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EBI DbfetchID AAS91649; SV 1; linear; mRNA; STD; ROD; 3819 BP. XX PA AY582535.1 XX DE Rattus norvegicus (Norway rat) multidrug resistance protein 1a XX OS Rattus norvegicus (Norway rat) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; OC Muridae; Murinae; Rattus. OX NCBI_TaxID=10116; XX FH Key Location/Qualifiers FH FT source 1..3819 FT /organism="Rattus norvegicus" FT /strain="Sprague-Dawley" FT /mol_type="mRNA" FT CDS AY582535.1:1..3819 FT /codon_start=1 FT /gene="Mdr1a" FT /product="multidrug resistance protein 1a" FT /note="P-glycoprotein" FT /db_xref="GOA:Q6PSM0" FT /db_xref="InterPro:IPR017940" FT /db_xref="UniProtKB/TrEMBL:Q6PSM0" FT /protein_id="AAS91649.1" FT /translation="MELEEDLNGRADKNFSKMGKKSKKEKKEKKPAVSVLTMFRYAGWL FT DRFYMLLGTLAAIIHGIALPLMMLVFGDMTDSFANVGNNRSMSFYNATDIYAKLKDEMT FT TYAYYYTGIGAGVLIVAYIQVSLWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGEL FT NTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAG FT IWAKILSSFTDKELQAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGI FT KKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYTIGQVLTVFFSVLIGAFSVGQA FT SPNIEAFANARGAAYEVFSIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKDV FT QILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEVSIDGQDIRTINVRYL FT REIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVG FT ERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIV FT IAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTAGNEIELGNEACE FT SKDGIDNVDMSSKDSGSSLIRRRSTRKSIRGPHDQDGELSTKEALDDDVPPASFWRILK FT LNSTEWPYFVVGVFCAIINGGLQPAFSIIFSKVVGVFTKNDTPEIQRQNSNLFSLLFLI FT LGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDISWFDDPKNTTGALTTRLAN FT DAAQVKGATGSRLAVITQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKML FT SGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNALKKAHVF FT GITFSFTQAMMYFSYAACFRFGAYLVARELMTFENVLLVFSAIVFGAMAVGQVSSFAPD FT YAKAKVSASHIIRIIEKIPEIDSYSTEGLKPNMLEGNVKFNGVMFNYPTRPNIPVLQGL FT SLEGKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEIKQLNVQWLRAHLGI FT VSQEPILFDCSIAENIAYGDNSRVVSHEEIVKAAKEANIHQFIDSLPEKYNTRVGDKGT FT QLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHR FT LSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYFSMVSVQAGAKRS" XX SQ Sequence 3819 BP; 1063 A; 855 C; 983 G; 918 T; 0 other; 4148453764 CRC32; atggagctcg aagaagacct taacggaaga gcagacaaga acttctcaaa gatgggcaaa 60 aagagtaaaa aggagaagaa agaaaagaaa ccagcggtca gtgtgctcac aatgtttcgc 120 tatgcaggtt ggctggacag attttacatg ctgctgggaa ctctggcggc cattatccat 180 ggaattgcgc tcccacttat gatgctggtc tttggagaca tgacagatag ctttgcaaat 240 gtaggaaaca accgtagtat gagtttctac aatgctacag acatatatgc caagctgaag 300 gacgaaatga ccacgtacgc ctactattac acgggcattg gtgccggtgt gctcatcgtt 360 gcctacatcc aggtttcact ttggtgcctg gcagctggga gacaaataca caagattagg 420 cagaagtttt tccatgccat catgaatcag gagataggct ggtttgacgt gcatgacgtt 480 ggggagctca acacccggct cacagatgac gtctccaaaa ttaatgaagg aattggtgac 540 aaaattggaa tgttctttca ggcaatggca acattttttg gtggttttat aataggattt 600 actcgcggct ggaagctaac tcttgtgatt ttggccatca gccctgttct tggactgtca 660 gctggtattt gggcaaagat attgtcttca tttactgata aggaactcca ggcttatgca 720 aaagctggag cagttgctga agaagtctta gcagccatca gaactgtgat tgcctttgga 780 ggacaaaaga aggaacttga aaggtacaat aacaatttgg aagaagctaa aaggcttggg 840 ataaagaaag ctatcacggc caacatttcc atgggtgcag cttttctgct tatctatgca 900 tcatatgctc tggcattctg gtatgggact tccttggtca tctcaaaaga atacactatt 960 ggacaagtgc tcactgtctt tttttctgta ttaattggag cattcagtgt tgggcaggca 1020 tctccaaata ttgaagcctt cgccaatgct agaggagcag cttatgaagt cttcagtata 1080 attgataata agcccagtat agacagcttc tcaaagagtg ggcacaaacc cgacaacata 1140 caaggaaatt tggaattcaa aaatattcac ttcagttacc cgtctcgaaa agacgttcag 1200 atcttgaagg gcctcaacct gaaggtgaag agcgggcaga cggtagccct ggttggcaac 1260 agtggctgtg ggaaaagcac aactgtccag ctgctgcaga ggctctacga ccccatagag 1320 ggcgaggtca gtatcgacgg acaggacatc aggaccatca atgtgaggta tctgcgggaa 1380 atcattgggg tggtgagtca ggaacccgtg ctgtttgcca ccacaattgc cgaaaacatt 1440 cgctatggcc gagaaaacgt caccatggat gagatagaga aagctgtcaa ggaagccaat 1500 gcctatgatt tcatcatgaa actgccccac aaatttgaca ccctggttgg tgagagaggg 1560 gcgcagctga gtgggggaca gaaacagagg atcgccattg cccgggccct ggtccgcaac 1620 cccaagatcc ttttgttgga tgaggccacg tcagccttgg acacagaaag cgaagccgtg 1680 gttcaggccg ctctggataa ggctagagaa ggccggacca ccattgtgat agctcaccgc 1740 ttgtctacag ttcgcaatgc tgatgtcatt gctggttttg atggtggtgt cattgtggag 1800 caaggaaatc atgatgagct catgagagag aaaggaattt acttcaaact tgtcatgact 1860 cagacagcag gaaatgaaat tgaattagga aatgaagctt gtgaatctaa agacggaatt 1920 gataatgtgg acatgtcttc aaaagattcg ggatccagtc taataagaag aagatcaact 1980 cgcaaaagca tccgtgggcc acatgatcaa gacggggaac ttagcaccaa agaggctctg 2040 gatgacgacg tacctccagc ttccttttgg cggatcctga agttgaattc aactgaatgg 2100 ccttattttg tggttggtgt attttgtgcc ataataaatg gaggcttgca accagcattc 2160 tccataatat tttcaaaggt tgtaggggtt tttacaaaaa atgacacccc tgaaatccag 2220 cggcagaaca gcaacttgtt ttctttattg ttcctgatcc ttgggatcat ctctttcatt 2280 acgtttttcc ttcagggctt cacatttggc aaagctggag agatcctcac caagcgactc 2340 cgatacatgg tcttcaaatc catgctgaga caggacataa gctggtttga tgaccctaaa 2400 aacaccacag gagcgctgac caccaggctt gccaatgacg ctgctcaagt gaaaggggct 2460 acagggtcta ggcttgctgt tattacccag aacatagcaa atcttgggac aggcatcatc 2520 atatccctga tctacggctg gcaattgaca cttttactcc tagcaattgt tcccatcatt 2580 gctatagcag gagtggttga aatgaaaatg ttgtctggac aagcgctgaa agataagaag 2640 gaactagaag gttctgggaa gatcgctaca gaagcaattg aaaactttcg cactgtcgtc 2700 tctttgactc gggagcagaa gtttgaaact atgtatgccc agagcttgca gataccatac 2760 agaaatgctt tgaagaaagc gcacgtcttt gggatcactt tctccttcac ccaggccatg 2820 atgtatttct cctatgctgc ttgtttccgg tttggtgcct acttggtggc acgagaactc 2880 atgacatttg aaaatgttct gttagtattc tcagctattg tctttggtgc catggcagtg 2940 gggcaggtca gttcattcgc tcctgactac gcgaaagcca aagtctcggc atcccacatc 3000 atcaggatca ttgagaaaat ccctgagatt gacagctaca gcacggaggg cttgaagcct 3060 aatatgttgg aaggaaatgt gaaatttaat ggagtcatgt tcaactatcc tacccgaccc 3120 aacatcccag tgcttcaggg gctgagccta gaggggaaga aagggcagac gctggccctc 3180 gtgggcagca gtggctgcgg gaagagtaca gtggtccagc tgcttgagcg cttctatgac 3240 cccatggccg gaacagtgtt tctagatggc aaagaaataa agcaactcaa tgtccagtgg 3300 ctccgcgccc acctgggcat tgtgtcccag gagcccatcc tgtttgactg cagcatcgcc 3360 gagaacattg cctacggaga caacagccgt gtcgtgtctc atgaggagat cgtgaaggca 3420 gccaaggagg ccaacatcca ccagttcatc gactcactgc ctgagaaata caacaccaga 3480 gtgggagaca aagggactca gctgtcgggc gggcagaagc agcgcatcgc catcgcgcgc 3540 gccctcgtca gacagcctca catcttactt ctggatgaag cgacatcagc tctggatacg 3600 gagagtgaaa aggtcgtcca ggaagcgctg gacaaagcca gggaaggccg cacctgcatt 3660 gtgatcgcgc accgcctgtc caccatccag aacgcagact tgatcgtggt gattcagaac 3720 ggccaggtca aggagcacgg cacccaccag cagctgctgg cccagaaagg catctatttc 3780 tccatggtca gtgtgcaggc tggagcaaag cgctcatga 3819 // |
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