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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AAK64870; SV 1; linear; genomic DNA; STD; PRO; 1371 BP.
XX
PA   AE006469.1
XX
DE   Sinorhizobium meliloti 1021 HisD2 histidinol dehydrogenase
XX
OS   Sinorhizobium meliloti 1021
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae;
OC   Sinorhizobium/Ensifer group; Sinorhizobium.
OG   Plasmid pSymA
OX   NCBI_TaxID=266834;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1371
FT                   /organism="Sinorhizobium meliloti 1021"
FT                   /plasmid="pSymA"
FT                   /strain="1021"
FT                   /mol_type="genomic DNA"
FT   CDS             AE006469.1:215421..216791
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="hisD2"
FT                   /locus_tag="SMa0398"
FT                   /product="HisD2 histidinol dehydrogenase"
FT                   /EC_number="1.1.1.23"
FT                   /note="FUNCTION: Catalyzes the sequential NAD-dependent
FT                   oxidations of L- histidinol to L-histidinaldehyde and then
FT                   to L-histidine (By similarity), CATALYTIC ACTIVITY: L-
FT                   histidinol phosphate + 2-oxoglutarate = 3- (imidazol-4-yl)-
FT                   2-oxopropyl phosphate + L-glutamate, CATALYTIC ACTIVITY:
FT                   L-histidinol + 2 NAD(+) = L-histidine + 2 NADH, COFACTOR:
FT                   Pyridoxal phosphate (By similarity); Binds 1 zinc ion per
FT                   subunit (By similarity), PATHWAY: Histidine biosynthesis;
FT                   seventh step, PATHWAY: Histidine biosynthesis; ninth (last)
FT                   step, SUBUNIT: Homodimer (By similarity), SIMILARITY: In
FT                   the N-terminal section; belongs to the histidinol
FT                   dehydrogenase family, SIMILARITY: In the C- terminal
FT                   section; belongs to the class-II pyridoxal-
FT                   phosphate-dependent aminotransferase family; Histidinol-
FT                   phosphate aminotransferase subfamily, function unclear"
FT                   /db_xref="GOA:Q930I4"
FT                   /db_xref="HSSP:1K75"
FT                   /db_xref="InterPro:IPR012131"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q930I4"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="AAK64870.1"
FT                   /translation="MTLRPQLARYKDKTMTSVSFYEYSKLNAEEKAALLRRSETDISGF
FT                   IEKVAPILEAVRTEGDKALARFGRELDKADVTEANLKVTAAEFDAAFKLVDASVLESVQ
FT                   FGIDNIRKFHEEQKPEAMWLKEIRPGAFAGDRFTPIQSVALYVPRGKGSFPSVTMMTSV
FT                   PAVVAGVPNLAIVTPPAPDGSVDAATLVAARLAGVETVYKAGGAQAVAAVAYGTETVKP
FT                   ALKIVGPGSPWVVAAKRSLSGVIDTGLPAGPSEVMILADDTVHGGLAALDLLIEAEHGP
FT                   DSSAYLVTHSGRVAEEALAALPEHWARMTEQRTAFSKTVLSGKTGGIVLTSSIEESYEF
FT                   VNAYAPEHLELLSEQPFIHLGHITEASEILMGTHTPVSIANFSLGPNAVLPTSRWARTF
FT                   GPLSVTDFVKRSSIGYVTAPAYPEFARHSHNLAIYEGFSSHALAVSPVRDAYLKKGA"
XX
SQ   Sequence 1371 BP; 259 A; 453 C; 403 G; 256 T; 0 other; 1154318390 CRC32;
     atgacccttc ggccccaact ggccagatac aaggacaaga cgatgacatc agtgtctttc        60
     tacgaatatt cgaagctgaa cgccgaagag aaggccgcct tgctgcgccg ttcggaaacc       120
     gacatatcgg gcttcatcga aaaggtcgcg ccgatcctcg aagcggtccg caccgagggc       180
     gacaaggcac tggcacgctt cggccgcgaa ctcgacaagg ccgatgtaac ggaagccaat       240
     ctcaaggtta cggcggcaga gttcgatgcg gccttcaagc tggttgatgc aagtgtcctc       300
     gagtccgttc aattcggcat cgacaacatc cgcaaattcc atgaggagca gaagccagaa       360
     gccatgtggc tgaaggagat ccgccccggc gcttttgccg gagaccgctt cacgcccatt       420
     cagtcggtcg cgctctacgt cccacggggc aagggctcct tcccgtcggt gactatgatg       480
     acatcggtcc cggccgtggt tgcaggcgtc ccgaacctgg ccattgtcac gccgccggcg       540
     ccggacggtt cggtcgatgc cgcgacgctg gttgctgcac gtctcgccgg cgttgaaacc       600
     gtctacaagg cgggcggcgc gcaggccgtt gctgctgtcg cctatggcac cgaaacggtc       660
     aagccggcgc tgaagatcgt cggtcccggc agcccttggg tggtcgccgc caagcgctcg       720
     ctctccggcg tcatcgatac cgggcttccc gctggtccgt ccgaggtgat gatcctcgcc       780
     gacgacacgg tccatggtgg ccttgccgcg ctcgacctgc tgatcgaggc cgaacatggc       840
     ccggattctt ccgcttacct cgttacccac agcggccgcg tcgccgagga ggcgctcgca       900
     gccctgccag aacactgggc gaggatgacc gaacagcgca ccgccttctc aaagaccgtg       960
     ctgagcggaa agacgggggg catcgtcctc acttcgtcga ttgaggaaag ctacgagttt      1020
     gtcaacgcct atgcgccgga gcatctggag ctcctgtcgg aacagccctt cattcatctg      1080
     ggccacatca ccgaagcttc cgaaatcctg atgggcaccc atactccggt cagcatcgcc      1140
     aatttctcgc tcgggcccaa cgccgtattg ccaaccagcc gctgggcccg caccttcggc      1200
     ccgctgtcgg tcaccgattt cgtcaaacgc agttcgatcg gctatgtcac ggcaccggcc      1260
     tatccggaat tcgccaggca ttcccacaat ctggcgatct acgagggctt ctcctcgcat      1320
     gcgcttgccg tatcgccggt gcgcgacgcc tatctgaaga agggcgcctg a               1371
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