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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AAK54388; SV 1; linear; mRNA; STD; MUS; 1164 BP.
XX
PA   AY033514.1
XX
DE   Mus musculus (house mouse) gamma-butyrobetaine 2-oxoglutarate dioxygenase
XX
OS   Mus musculus (house mouse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea;
OC   Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1164
FT                   /organism="Mus musculus"
FT                   /strain="FVB/N"
FT                   /mol_type="mRNA"
FT                   /sex="male"
FT   CDS             AY033514.1:32..1195
FT                   /codon_start=1
FT                   /product="gamma-butyrobetaine 2-oxoglutarate dioxygenase"
FT                   /function="converts gamma-butyrobetaine
FT                   (4-trimethylammoniobutanoate), alpha-ketoglutarate and
FT                   molecular oxygen into carnitine
FT                   (3-hydroxy-4-trimethylammoniobutanoate), succinate and CO2"
FT                   /EC_number="1.14.11.1"
FT                   /note="gamma-butyrobetaine hydroxylase;
FT                   alpha-ketoglutarate-dependent dioxygenase; mediates the
FT                   last step in carnitine biosynthesis; iron (2+) and
FT                   ascorbate are co-factors"
FT                   /db_xref="GOA:Q924Y0"
FT                   /db_xref="InterPro:IPR003819"
FT                   /db_xref="MGI:1891372"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q924Y0"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="AAK54388.1"
FT                   /translation="MHCAILKAEAVDGAHLMQIFWHDGAESLYPAVWLRDNCQCSDCYL
FT                   HSAKARKLLLEALDVNIRIDDLTFDRKKVYITWPNDHYSEFEANWLKKRCFSQQARARL
FT                   QGELFLPECQYWGSELQLPTLNFEDVLNDDDHAYKWLSSLKKVGIVRLTGAADKRGEII
FT                   KLGKRIGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQ
FT                   TVTGGDSEIVDGFNVCQKLKEKNPQAFHILSSTFVDFTDIGVDYCDFSVQSKHKIIELD
FT                   DKGQVVRVNFNNATRDTVFDVPIERVQPFYAALKEFVDLMNSKEYKYTFKMNPGDVITF
FT                   DNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVTNGN"
XX
SQ   Sequence 1164 BP; 337 A; 252 C; 278 G; 297 T; 0 other; 3724647660 CRC32;
     atgcactgtg ccatcctaaa ggcagaagca gtggatgggg ctcatttgat gcagatcttt        60
     tggcacgatg gggcagagtc cctctaccca gcagtatggc tgagagacaa ctgtcagtgt       120
     tcagactgct acctacattc tgcaaaagct cggaaacttc tcctggaagc tcttgatgta       180
     aacattagaa tcgatgattt gacatttgac cggaaaaagg tttatatcac atggcccaat       240
     gaccattaca gtgaattcga agctaactgg ctgaagaaaa gatgcttttc tcaacaggcc       300
     agagcaaggc tccaaggaga attgttttta ccagaatgtc agtactgggg ctcagaactc       360
     cagctgccaa ctctgaattt tgaagatgtg ttaaatgatg atgaccatgc atacaaatgg       420
     ctttccagtc tcaagaaagt aggcattgtg agactcaccg gagcagctga caaacgtggt       480
     gagatcataa aacttggaaa aagaattggc ttcctgtacc tcacatttta tggacacact       540
     tggcaagtgc aggacaagat tgatgccaac aatgtggctt atacaactgg gaagctcagc       600
     ttccacactg actacccagc cctccaccat ccacctgggg ttcagcttct gcattgtatc       660
     aagcaaacag tcacaggagg tgactctgaa attgtggatg ggtttaacgt gtgccaaaag       720
     ctcaaggaga agaaccctca ggctttccat attctctcct cgacctttgt ggattttaca       780
     gacattggag tggattactg tgatttctct gtgcaatcta aacacaagat tatagagttg       840
     gatgataaag gccaagtggt tcgcgtcaac ttcaacaatg caaccagaga tacagtcttt       900
     gatgtcccca tcgaaagagt tcagcctttc tacgctgctc tgaaagagtt tgttgacctc       960
     atgaacagca aagaatacaa gtataccttc aagatgaatc caggtgatgt gattaccttc      1020
     gacaactggc gcttgcttca tggacgtcgt agctatgagg cgggaactga gatatcccgc      1080
     catctggaag gagcgtatgc tgactgggat gtagtgatgt caaggcttcg tattctgaga      1140
     cagagagtca cgaatgggaa ctga                                             1164
//
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