EBI Dbfetch

ID   AAD54507; SV 1; linear; genomic DNA; STD; HUM; 2898 BP.
XX
PA   AC010077.1
XX
DE   Homo sapiens (human) partial MTDM_HUMAN [AA 1-966]
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..2898
FT                   /organism="Homo sapiens"
FT                   /chromosome="19"
FT                   /map="19p13.2 between D19S391 and D19S179"
FT                   /mol_type="genomic DNA"
FT                   /clone_lib="LL19NC03 R chromosome 19-specific cosmid
FT                   library"
FT                   /clone="R28278"
FT                   /cell_line="5HL-2"
FT   CDS             complement(join(AC010077.1:<643..835,AC010077.1:2381..2602,
FT                   AC010077.1:4966..5139,AC010077.1:7499..7632,
FT                   AC010077.1:8068..8272,AC010077.1:8468..8583,
FT                   AC010077.1:10013..10160,AC010077.1:10365..10462,
FT                   AC010077.1:12908..13094,AC010077.1:13201..13388,
FT                   AC010077.1:13520..13671,AC010077.1:14468..14560,
FT                   AC010077.1:15006..15124,AC010077.1:18273..18382,
FT                   AC010077.1:18457..18537,AC010077.1:18633..18678,
FT                   AC010077.1:18999..19033,AC010077.1:21282..21363,
FT                   AC010077.1:21941..21975,AC010077.1:25213..25300,
FT                   AC010077.1:26945..26979,AC010077.1:31705..31789,
FT                   AC010077.1:32486..32520,AC010077.1:34155..34233,
FT                   AC010077.1:35907..35982,AC010077.1:38965..39046))
FT                   /codon_start=1
FT                   /gene="DNMT"
FT                   /product="MTDM_HUMAN [AA 1-966]"
FT                   /function="METHYLATES CG RESIDUES"
FT                   /EC_number="2.1.1.37"
FT                   /note="DNA (CYTOSINE-5)-METHYLTRANSFERASE; DNA
FT                   METHYLTRANSFERASE; DNA METASE; MCMT; M.HSAI"
FT                   /db_xref="GDB:127606"
FT                   /db_xref="GOA:P26358"
FT                   /db_xref="HGNC:2976"
FT                   /db_xref="InterPro:IPR002857"
FT                   /db_xref="PDB:3EPZ"
FT                   /db_xref="UniProtKB/Swiss-Prot:P26358"
FT                   /func_characterised="similar sequence"
FT                   /protein_id="AAD54507.1"
FT                   /translation="MADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTT
FT                   ITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERA
FT                   KSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK
FT                   KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTV
FT                   MNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEAL
FT                   PQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPI
FT                   NEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNS
FT                   DSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTP
FT                   CMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEK
FT                   DDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMK
FT                   EADDDEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAET
FT                   LEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELF
FT                   LVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYA
FT                   RFESPPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILY
FT                   RVGDGVYLPPEAFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYR
FT                   IGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVV
FT                   DFKAVQGRCTVEYGEDLPECVQVYSMGGPNRFYFLE"
XX
SQ   Sequence 2898 BP; 854 A; 748 C; 797 G; 499 T; 0 other; 850511461 CRC32;
     atggcagatg ccaacagccc ccccaaaccc ctttccaaac ctcgcacgcc caggaggagc        60
     aagtccgatg gagaggctaa gcctgaacct tcacctagcc ccaggattac aaggaaaagc       120
     accaggcaaa ccaccatcac atctcatttt gcaaagggcc ctgccaaacg gaaacctcag       180
     gaagagtctg aaagagccaa atcggatgag tccatcaagg aagaagacaa agaccaggat       240
     gagaagagac gtagagttac atccagagaa cgagttgcta gaccgcttcc tgcagaagaa       300
     cctgaaagag caaaatcagg aacgcgcact gaaaaggaag aagaaagaga tgaaaaagaa       360
     gaaaagagac tccgaagtca aaccaaagaa ccaacaccca aacagaaact gaaggaggag       420
     ccggacagag aagccagggc aggcgtgcag gctgacgagg acgaagatgg agacgagaaa       480
     gatgagaaga agcacagaag tcaacccaaa gatctagctg ccaaacggag gcccgaagaa       540
     aaagaacctg aaaaagtaaa tccacagatt tctgatgaaa aagacgagga tgaaaaggag       600
     gagaagagac gcaaaacgac ccccaaagaa ccaacggaga aaaaaatggc tcgcgccaaa       660
     acagtcatga actccaagac ccaccctccc aagtgcattc agtgcgggca gtacctggac       720
     gaccctgacc tcaaatatgg gcagcaccca ccagacgcgg tggatgagcc acagatgctg       780
     acaaatgaga agctgtccat ctttgatgcc aacgagtctg gctttgagag ttatgaggcg       840
     cttccccagc acaaactgac ctgcttcagt gtgtactgta agcacggtca cctgtgtccc       900
     atcgacaccg gcctcatcga gaagaatatc gaactcttct tttctggttc agcaaaacca       960
     atctatgatg atgacccatc tcttgaaggt ggtgttaatg gcaaaaatct tggccccata      1020
     aatgaatggt ggatcactgg ctttgatgga ggtgaaaagg ccctcatcgg cttcagcacc      1080
     tcatttgccg aatacattct gatggatccc agtcccgagt atgcgcccat atttgggctg      1140
     atgcaggaga agatctacat cagcaagatt gtggtggagt tcctgcagag caattccgac      1200
     tcgacctatg aggacctgat caacaagatc gagaccacgg ttcctccttc tggcctcaac      1260
     ttgaaccgct tcacagagga ctccctcctg cgacacgcgc agtttgtggt ggagcaggtg      1320
     gagagttatg acgaggccgg ggacagtgat gagcagccca tcttcctgac accctgcatg      1380
     cgggacctga tcaagctggc tggggtcacg ctgggacaga ggcgagccca ggcgaggcgg      1440
     cagaccatca ggcattctac cagggagaag gacaggggac ccacgaaagc caccaccacc      1500
     aagctggtct accagatctt cgatactttc ttcgcagagc aaattgaaaa ggatgacaga      1560
     gaagacaagg agaacgcctt taagcgccgg cgatgtggcg tctgtgaggt gtgtcagcag      1620
     cctgagtgtg ggaaatgtaa agcctgcaag gacatggtta aatttggtgg cagtggacgg      1680
     agcaagcagg cttgccaaga gcggaggtgt cccaatatgg ccatgaagga ggcagatgac      1740
     gatgaggaag tcgatgataa catcccagag atgccgtcac ccaaaaaaat gcaccagggg      1800
     aagaagaaga aacagaacaa gaatcgcatc tcttgggtcg gagaagccgt caagactgat      1860
     gggaagaaga gttactataa gaaggtgtgc attgatgcgg aaaccctgga agtgggggac      1920
     tgtgtctctg ttattccaga tgattcctca aaaccgctgt atctagcaag ggtcacggcg      1980
     ctgtgggagg acagcagcaa cgggcagatg tttcacgccc actggttctg cgctgggaca      2040
     gacacagtcc tcggggccac gtcggaccct ctggagctgt tcttggtgga tgaatgtgag      2100
     gacatgcagc tttcatatat ccacagcaaa gtgaaagtca tctacaaagc cccctccgaa      2160
     aactgggcca tggagggagg catggatccc gagtccctgc tggaggggga cgacgggaag      2220
     acctacttct accagctgtg gtatgatcaa gactacgcga gattcgagtc ccctccaaaa      2280
     acccagccaa cagaggacaa caagttcaaa ttctgtgtga gctgtgcccg tctggctgag      2340
     atgaggcaaa aagaaatccc cagggtcctg gagcagctcg aggacctgga tagccgggtc      2400
     ctctactact cagccaccaa gaacggcatc ctgtaccgag ttggtgatgg tgtgtacctg      2460
     ccccctgagg ccttcacgtt caacatcaag ctgtccagtc ccgtgaaacg cccacggaag      2520
     gagcccgtgg atgaggacct gtacccagag cactaccgga aatactccga ctacatcaaa      2580
     ggcagcaacc tggatgcccc tgagccctac cgaattggcc ggatcaaaga gatcttctgt      2640
     cccaagaaga gcaacggcag gcccaatgag actgacatca aaatccgggt caacaagttc      2700
     tacaggcctg agaacaccca caagtccact ccagcgagct accacgcaga catcaacctg      2760
     ctctactgga gcgacgagga ggccgtggtg gacttcaagg ctgtgcaggg ccgctgcacc      2820
     gtggagtatg gggaggacct gcccgagtgc gtccaggtgt actccatggg cggccccaac      2880
     cgcttctact tcctcgag                                                    2898
//