EBI Dbfetch

ID   AAC69621; SV 1; linear; mRNA; STD; HUM; 1494 BP.
XX
PA   AF077367.1
XX
DE   Homo sapiens (human) thioredoxin reductase GRIM-12
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1494
FT                   /organism="Homo sapiens"
FT                   /mol_type="mRNA"
FT                   /cell_line="BT-20"
FT                   /tissue_type="breast carcinoma"
FT   CDS             AF077367.1:129..1622
FT                   /codon_start=1
FT                   /product="thioredoxin reductase GRIM-12"
FT                   /note="associated with retinoic acid/interferon-beta
FT                   induced mortality"
FT                   /db_xref="GOA:Q16881"
FT                   /db_xref="HGNC:12437"
FT                   /db_xref="InterPro:IPR012335"
FT                   /db_xref="PDB:1W1C"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q16881"
FT                   /func_characterised="similar sequence"
FT                   /protein_id="AAC69621.1"
FT                   /translation="MNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVT
FT                   PTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEA
FT                   VQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGE
FT                   RPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLNVTVMVRS
FT                   ILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIE
FT                   GEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKV
FT                   ELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENI
FT                   EVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKC
FT                   GLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGARILQAGC"
XX
SQ   Sequence 1494 BP; 446 A; 287 C; 385 G; 376 T; 0 other; 2701117650 CRC32;
     atgaacggcc ctgaagatct tcccaagtcc tatgactatg accttatcat cattggaggt        60
     ggctcaggag gtctggcagc tgctaaggag gcagcccaat atggcaagaa ggtgatggtc       120
     ctggactttg tcactcccac ccctcttgga actagatggg gtctcggagg aacatgtgtg       180
     aatgtgggtt gcatacctaa aaaactgatg catcaagcag ctttgttagg acaagccctg       240
     caagactctc gaaattatgg atggaaagtc gaggagacag ttaagcatga ttgggacaga       300
     atgatagaag ctgtacagaa tcacattggc tctttgaatt ggggctaccg agtagctctg       360
     cgggagaaaa aagtcgtcta tgagaatgct tatgggcaat ttattggtcc tcacaggatt       420
     aaggcaacaa ataataaagg caaagaaaaa atttattcag cagagagatt tctcattgcc       480
     actggtgaaa gaccacgtta cttgggcatc cctggtgaca aagaatactg catcagcagt       540
     gatgatcttt tctccttgcc ttactgcccg ggtaagaccc tggttgttgg agcatcctat       600
     gtcgctttgg agtgcgctgg atttcttgct ggtattggtt taaacgtcac tgttatggtt       660
     aggtccattc ttcttagagg atttgaccag gacatggcca acaaaattgg tgaacacatg       720
     gaagaacatg gcatcaagtt tataagacag ttcgtaccaa ttaaagttga acaaattgaa       780
     gcagggacac caggccgact cagagtagta gctcagtcca ccaatagtga ggaaatcatt       840
     gaaggagaat ataatacggt gatgctggca ataggaagag atgcttgcac aagaaaaatt       900
     ggcttagaaa ccgtaggggt gaagataaat gaaaagactg gaaaaatacc tgtcacagat       960
     gaagaacaga ccaatgtgcc ttacatctat gccattggcg atatattgga ggataaggtg      1020
     gagctcaccc cagttgcaat ccaggcagga agattgctgg ctcagaggct ctatgcaggt      1080
     tccactgtca agtgtgacta tgaaaatgtt ccaaccactg tatttactcc tttggaatat      1140
     ggtgcttgtg gcctttctga ggagaaagct gtggagaagt ttggggaaga aaatattgag      1200
     gtttaccata gttacttttg gccattggaa tggacgattc cgtcaagaga taacaacaaa      1260
     tgttatgcaa aaataatctg taatactaaa gacaatgaac gtgttgtggg ctttcacgta      1320
     ctgggtccaa atgctggaga agttacacaa ggctttgcag ctgcgctcaa atgtggactg      1380
     accaaaaagc agctggacag cacaattgga atccaccctg tctgtgcaga ggtattcaca      1440
     acattgtctg tgaccaagcg ctctggggca aggatcctcc aggctggctg ctga            1494
//