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EBI DbfetchID AAC50236; SV 1; linear; mRNA; STD; HUM; 4488 BP. XX PA U37146.1 XX DE Homo sapiens (human) silencing mediator of retinoid and thyroid hormone DE action XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606; XX FH Key Location/Qualifiers FH FT source 1..4488 FT /organism="Homo sapiens" FT /mol_type="mRNA" FT /cell_line="HeLa" FT CDS U37146.1:496..4983 FT /codon_start=1 FT /gene="SMRT" FT /product="silencing mediator of retinoid and thyroid FT hormone action" FT /note="transcriptional co-repressor" FT /db_xref="GOA:Q9Y618" FT /db_xref="HGNC:7673" FT /db_xref="InterPro:IPR017884" FT /db_xref="PDB:1KKQ" FT /db_xref="UniProtKB/Swiss-Prot:Q9Y618" FT /func_characterised="similar sequence" FT /protein_id="AAC50236.1" FT /translation="MEAWDAHPDKEAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASP FT HAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAIS FT QGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLG FT VPTAQEASVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTIT FT RIIGEDSPSRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHE FT TAAPKRTYDMMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRS FT YVEAQEDYLRREAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEA FT GRSIHEIPREELRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSP FT GRTFPPVHPLDVMADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQS FT PLTYEDHGAPFAGHLPRGSPVTMREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHS FT TVPEHHPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAP FT NPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHNTATAMAQRADMLRGLSPR FT ESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSS FT PLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQS FT SGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPS FT KPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPR FT ADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDP FT PAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGL FT PKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGH FT QRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPP FT DHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYR FT DGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNI FT SQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGKYDQWEESPPLSA FT NAFNPLNASASLPAAMPITAADGRSDHTLTSPGGGGKAKVSGRPSSRKAKSPAPGLASG FT DRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPG FT LPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE" XX SQ Sequence 4488 BP; 876 A; 1766 C; 1253 G; 593 T; 0 other; 1475088455 CRC32; atggaggcat gggacgccca ccccgacaag gaggccttcg cagccgaggc ccagaagctg 60 cctggggacc ccccttgctg gacttccggc ctgcccttcc ccgtgccccc ccgtgaggtg 120 atcaaggcct ccccgcatgc cccggacccc tcagccttct cctacgctcc acctggtcac 180 ccactgcccc tgggcctcca tgacactgcc cggcccgtcc tgccgcgccc acccaccatc 240 tccaacccgc ctcccctcat ctcctctgcc aagcacccca gcgtcctcga gaggcaaata 300 ggtgccatct cccaaggaat gtcggtccag ctccacgtcc cgtactcaga gcatgccaag 360 gccccggtgg gccctgtcac catggggctg cccctgccca tggaccccaa aaagctggca 420 cccttcagcg gagtgaagca ggagcagctg tccccacggg gccaggctgg gccaccggag 480 agcctggggg tgcccacagc ccaggaggcg tccgtgctga gagggacagc tctgggctca 540 gttccgggcg gaagcatcac caaaggcatt cccagcacac gggtgccctc ggacagcgcc 600 atcacatacc gcggctccat cacccacggc acgccagctg acgtcctgta caagggcacc 660 atcaccagga tcatcggcga ggacagcccg agtcgcttgg accgcggccg ggaggacagc 720 ctgcccaagg gccacgtcat ctacgaaggc aagaagggcc acgtcttgtc ctatgagggt 780 ggcatgtctg tgacccagtg ctccaaggag gacggcagaa gcagctcagg acccccccat 840 gagacggccg cccccaagcg cacctatgac atgatggagg gccgcgtggg cagagccatc 900 tcctcagcca gcatcgaagg tctcatgggc cgtgccatcc cgccggagcg acacagcccc 960 caccacctca aagagcagca ccacatccgc gggtccatca cacaagggat ccctcggtcc 1020 tacgtggagg cacaggagga ctacctgcgt cgggaggcca agctcctaaa gcgggagggc 1080 acgcctccgc ccccaccgcc ctcacgggac ctgaccgagg cctacaagac gcaggccctg 1140 ggccccctga agctgaagcc ggcccatgag ggcctggtgg ccacggtgaa ggaggcgggc 1200 cgctccatcc atgagatccc gcgcgaggag ctgcggcaca cgcccgagct gcccctggcc 1260 ccgcggccgc tcaaggaggg ctccatcacg cagggcaccc cgctcaagta cgacaccggc 1320 gcgtccacca ctggctccaa aaagcacgac gtacgctccc tcatcggcag ccccggccgg 1380 acgttcccac ccgtgcaccc gctggatgtg atggccgacg cccgggcact ggaacgtgcc 1440 tgctacgagg agagcctgaa gagccggcca gggaccgcca gcagctcggg gggctccatt 1500 gcgcgcggcg ccccggtcat tgtgcctgag ctgggtaagc cgcggcagag ccccctgacc 1560 tatgaggacc acggggcacc ctttgccggc cacctcccac gaggttcgcc cgtgaccatg 1620 cgggagccca cgccgcgcct gcaggagggc agcctttcgt ccagcaaggc atcccaggac 1680 cgaaagctga cgtcgacgcc tcgtgagatc gccaagtccc cgcacagcac cgtgcccgag 1740 caccacccac accccatctc gccctatgag cacctgcttc ggggcgtgag tggcgtggac 1800 ctgtatcgca gccacatccc cctggccttc gaccccacct ccataccccg cggcatccct 1860 ctggacgcag ccgctgccta ctacctgccc cgacacctgg cccccaaccc cacctacccg 1920 cacctgtacc caccctacct catccgcggc taccccgaca cggcggcgct ggagaaccgg 1980 cagaccatca tcaatgacta catcacctcg cagcagatgc accacaacac ggccaccgcc 2040 atggcccagc gagctgatat gctgaggggc ctctcgcccc gcgagtcctc gctggcactc 2100 aactacgctg cgggtccccg aggcatcatc gacctgtccc aagtgccaca cctgcctgtg 2160 ctcgtgcccc cgacaccagg caccccagcc accgccatgg accgccttgc ctacctcccc 2220 accgcgcccc agcccttcag cagccgccac agcagctccc cactctcccc aggaggtcca 2280 acacacttga caaaaccaac caccacgtcc tcgtccgagc gggagcgaga ccgggatcga 2340 gagcgggacc gggatcggga gcgggaaaag tccatcctca cgtccaccac gacggtggag 2400 cacgcaccca tctggagacc tggtacagag cagagcagcg gcagcagcgg cagcagcggc 2460 gggggtgggg gcagcagcag ccgccccgcc tcccactccc atgcccacca gcactcgccc 2520 atctcccctc ggacccagga tgccctccag cagagaccca gtgtgcttca caacacaggc 2580 atgaagggta tcatcaccgc tgtggagccc agcaagccca cggtcctgag gtccacctcc 2640 acctcctcac ccgttcgccc agctgccaca ttcccacctg ccacccactg cccactgggc 2700 ggcaccctcg atggggtcta ccctaccctc atggagcccg tcttgctgcc caaggaggcc 2760 ccccgggtcg cccggccaga gcggccccga gcagacaccg gccatgcctt cctcgccaag 2820 cccccagccc gctccgggct ggagcccgcc tcctccccca gcaagggctc ggagccccgg 2880 cccctagtgc ctcctgtctc tggccacgcc accatcgccc gcacccctgc gaagaacctc 2940 gcacctcacc acgccagccc ggacccgccg gcgccacctg cctcggcctc ggacccgcac 3000 cgggaaaaga ctcaaagtaa acccttttcc atccaggaac tggaactccg ttctctgggt 3060 taccacggca gcagctacag ccccgaaggg gtggagcccg tcagccctgt gagctcaccc 3120 agtctgaccc acgacaaggg gctccccaag cacctggaag agctcgacaa gagccacctg 3180 gagggggagc tgcggcccaa gcagccaggc cccgtgaagc ttggcgggga ggccgcccac 3240 ctcccacacc tgcggccgct gcctgagagc cagccctcgt ccagcccgct gctccagacc 3300 gccccagggg tcaaaggtca ccagcgggtg gtcaccctgg cccagcacat cagtgaggtc 3360 atcacacagg actacacccg gcaccaccca cagcagctca gcgcacccct gcccgccccc 3420 ctctactcct tccctggggc cagctgcccc gtcctggacc tccgccgccc acccagtgac 3480 ctctacctcc cgcccccgga ccatggtgcc ccggcccgtg gctcccccca cagcgaaggg 3540 ggcaagaggt ctccagagcc aaacaagacg tcggtcttgg gtggtggtga ggacggtatt 3600 gaacctgtgt ccccaccgga gggcatgacg gagccagggc actcccggag tgctgtgtac 3660 ccgctgctgt accgggatgg ggaacagacg gagcccagca ggatgggctc caagtctcca 3720 ggcaacacca gccagccgcc agccttcttc agcaagctga ccgagagcaa ctccgccatg 3780 gtcaagtcca agaagcaaga gatcaacaag aagctgaaca cccacaaccg gaatgagcct 3840 gaatacaata tcagccagcc tgggacggag atcttcaata tgcccgccat caccggaaca 3900 ggccttatga cctatagaag ccaggcggtg caggaacatg ccagcaccaa catggggctg 3960 gaggccataa ttagaaaggc actcatgggt aaatatgacc agtgggaaga gtccccgccg 4020 ctcagcgcca atgcttttaa ccctctgaat gccagtgcca gcctgcccgc tgctatgccc 4080 ataaccgctg ctgacggacg gagtgaccac acactcacct cgccaggtgg cggcgggaag 4140 gccaaggtct ctggcagacc cagcagccga aaagccaagt ccccggcccc gggcctggca 4200 tctggggacc ggccaccctc tgtctcctca gtgcactcgg agggagactg caaccgccgg 4260 acgccgctca ccaaccgcgt gtgggaggac aggccctcgt ccgcaggttc cacgccattc 4320 ccctacaacc ccctgatcat gcggctgcag gcgggtgtca tggcttcccc acccccaccg 4380 ggcctccccg cgggcagcgg gcccctcgct ggcccccacc acgcctggga cgaggagccc 4440 aagccactgc tctgctcgca gtacgagaca ctctccgaca gcgagtga 4488 // |
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