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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AAB69279; SV 2; linear; mRNA; STD; MAM; 765 BP.
XX
PA   AF008440.2
XX
DE   Sus scrofa (pig) steroid 5-alpha-reductase 2
XX
OS   Sus scrofa (pig)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..765
FT                   /organism="Sus scrofa"
FT                   /mol_type="mRNA"
FT                   /sex="male"
FT                   /tissue_type="epididymus"
FT   CDS             AF008440.2:42..806
FT                   /codon_start=1
FT                   /gene="ST5AR2"
FT                   /product="steroid 5-alpha-reductase 2"
FT                   /function="converts testosterone into
FT                   5-alpha-dihydrotestosterone"
FT                   /function="converts progesterone or corticosterone into
FT                   their corresponding 5-alpha-3-oxosteroids"
FT                   /EC_number="1.3.99.5"
FT                   /note="type 2; 4-ene-3-oxosteroid 5-alpha oxidoreductase;
FT                   reduced or excessive levels can cause incomplete
FT                   differentitation of male external genitalia, prostate
FT                   cancer, and female hirsutism in Homo sapiens; expressed at
FT                   high levels in androgen-sensitive tissues"
FT                   /db_xref="GOA:O18765"
FT                   /db_xref="InterPro:IPR001104"
FT                   /db_xref="UniProtKB/Swiss-Prot:O18765"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="AAB69279.2"
FT                   /translation="MPVRCQQSPVLAGSATLAALGALALYFAEPSGYGKYTESLTPAAI
FT                   RLPARAAWFLQELPSFVVPAGILAGQPRSLFGPPATVLLGLFCAHYFHRTFVYSLLTRG
FT                   RPFPVVFLFRGFVFCMGNGLLQGYYLVYCAEYPAEWYTDIRFSLGVFLFILGMGINIHS
FT                   DYILRQLRKPGEVIYKIPQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLC
FT                   FLGLRAFHHHRFYVKMFEDYPKSRKALIPFIF"
XX
SQ   Sequence 765 BP; 132 A; 218 C; 194 G; 221 T; 0 other; 2757548101 CRC32;
     atgcctgttc gctgccagca gagcccggtg ctggcgggca gcgccacttt ggctgccctg        60
     ggggcactgg ccctgtactt cgcggagccc tctggctacg ggaagtacac ggagagcctg       120
     acgcccgcgg ctatccgcct gccagcccgt gccgcctggt tcctgcagga gctgccctcc       180
     ttcgtggtgc ccgcggggat cctcgccggg cagccccgtt ctctcttcgg cccgcctgcg       240
     actgtgcttc tgggcctctt ctgcgcacat tacttccaca ggacatttgt ttactcactg       300
     ctcactagag ggaggccttt tccagttgta ttccttttca gaggctttgt cttctgcatg       360
     ggaaatggac tccttcaagg ctactatctg gtttactgtg ccgaataccc tgctgagtgg       420
     tacacagaca tacggtttag cctaggtgtg ttcttattta ttttgggcat gggaatcaac       480
     attcacagcg actatatatt gcgccagctc aggaagcctg gagaagtcat ctataagatt       540
     ccacaaggtg gcttgttcac gtacgtttct ggagccaatt tccttggtga gatcattgaa       600
     tggatcggct atgccttggc cacttggtcc cttccagcac ttgcatttgc atttttctcg       660
     ctttgtttcc ttgggctgcg agcttttcac catcataggt tctacgtcaa gatgtttgag       720
     gactacccca agtctcgaaa agcccttatt ccatttatct tttaa                       765
//
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