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EBI DbfetchID AAB58382; SV 1; linear; mRNA; STD; HUM; 7452 BP. XX PA U89344.1 XX DE Homo sapiens (human) acetyl-CoA carboxylase XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606; XX FH Key Location/Qualifiers FH FT source 1..7452 FT /organism="Homo sapiens" FT /chromosome="12" FT /map="12q23" FT /mol_type="mRNA" FT /sex="male" FT /dev_stage="adult" FT /clone_lib="Clontech catalog number 7300-1" FT /tissue_type="liver" FT CDS U89344.1:1..7452 FT /codon_start=1 FT /gene="ACC2" FT /product="acetyl-CoA carboxylase" FT /function="synthesis of malonyl-CoA" FT /EC_number="6.4.1.2" FT /note="acc280" FT /db_xref="GDB:5200247" FT /db_xref="GOA:O00763" FT /db_xref="HGNC:85" FT /db_xref="InterPro:IPR013817" FT /db_xref="PDB:2DN8" FT /db_xref="UniProtKB/Swiss-Prot:O00763" FT /func_characterised="similar sequence" FT /protein_id="AAB58382.1" FT /translation="MVLLLCLSCLIFSCLTFSWLKIWEKMTDSKPITKSKSEANLIPSQ FT EPFPASDNSGETPQRNGEGHTLHKDTQPGRAQPPTKAQRSGRRRNSLPPSRQKPPRNPL FT SSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGSKLVPSKEDKKQANIKRQLMTN FT FILGSFDDYSSDEDSVAGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSG FT LHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRW FT AYEMFRNERAIRFVRMVTPEDLKANAEYIKMADHYGPAPGGPNNNNYANVELIVDIAKR FT IPLQAVWAGWGHALENPKLPELLCKNGVAFLGPPRLRPMVGLGDKIASTVVAQTLQVPT FT LPRSGSALTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEG FT GGGKGIRETESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLF FT GRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSF FT HFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGAPLHRLKDIRLLYGESPWGDSPISF FT ENSAHLPCPRGHVIATRITSENPDEGFKPSSGTVQELNFRSSKNVWGYFTVAATGGLHE FT FAISQFGHCFSWGENRKEAISNMVVALKELSLRGDFRTTVEYLINLLETESFQNNYIDT FT GWLDYLIAEKVQKKPNIMLGVVCGALERGDAMFRTCMTDFLHSLERGQVLPADSLLNLV FT DVELIYEGVKYILKVTRQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKE FT EVDSYRTIGNKTCVFEKENDPTVLRSPSAGKLTQITVEDGGHVEAGRRYAEMEVMKMIM FT TLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQNTADLGKK FT LHRVFHSVLGSLTNVMSGFCLPEPFFSIKLKEWVQKLMMTLRHPSLLLDVQEIMTSRAG FT RIPPPVEKSVRKVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFINTQS FT MVQLVQRYRSGIRGHMKTVVIDLLRRYLRVETIFGKARDADANSSGMVGGVRSLSFTSV FT WVVLSPPAHYDKCVINLREQFKPDMSQVLDCIFSHAQVTKKNQLVIMLIDELCGPDPSL FT SDELISILNELTQLSKSEHCKVALRARQILIASPSYELRHNQVESIFLSAIDMYGHQFC FT PENLQKLILSETTIFDVLNTFFYHANKVVCMASLEVYVGGAYIAYVLNSLQHRQLPDGT FT CVVEFQFMLPSSHPNRMTVPISITNPDLLRHTTELFMDSGFSPLCQRMGAMVAFRRFED FT FTRNFDEVISCFANVPKDPPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDE FT ALVPILRTFVQSKKNILVDYGLRRIPFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPA FT LAFQLELNRMRNFDLTAVPCANHKMHLYLGAAKVEGRYEVTDHRFFIRAIIRHSDLITK FT EASFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPNKIEESVRY FT MVMRYGSRLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRS FT GNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKL FT WGSPDKYPKDILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIV FT IGNDITFRIGSFGPGEDLLYLRASEMARAEAIPKIYVAANSGARIGMAEEIKHMFHVAW FT VDPEDPHKGFKYLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENL FT RGSGMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNK FT VLGREVYTSNNQLGGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITP FT TDPIDREIEFLPSRAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTG FT RARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDF FT NREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIRPMRELRGGS FT WVVIDATINPLCIEMYADKESRGGVLEPEGTVEIKFRKEDLIKSMRRIDPAYKKLMEQL FT GEPDLSDKDRKDLEGRLKAREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKT FT ARTFLYWRLRRLLLEDQVKQEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQV FT VVQWLEQHWQAGDGPRSTIRENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISP FT AERAQVVHLLSTMDSPAST" XX SQ Sequence 7452 BP; 1787 A; 2076 C; 2066 G; 1523 T; 0 other; 2973678906 CRC32; atggtcttgc ttctttgtct atcttgtctg attttctcct gtctgacctt ttcctggtta 60 aaaatctggg agaaaatgac ggactccaag ccgatcacca agagtaaatc agaagcaaac 120 ctcatcccga gccaggagcc ctttccagcc tctgataact caggggagac accgcagaga 180 aatggggagg gccacactct gcacaaagac acccagccag gccgagccca gcctcccaca 240 aaggcccaaa gatccggtcg gcggagaaac tccctaccac cctcccgcca gaagccccca 300 agaaaccccc tttcttccag tgacgcagca ccctccccag agcttcaagc caacgggact 360 gggacacaag gtctggaggc cacagatacc aatggcctgt cctcctcagc caggccccag 420 ggcagcaagc tggtcccctc caaagaagac aagaagcagg caaacatcaa gaggcagctg 480 atgaccaact tcatcctggg ctcttttgat gactactcct ccgacgagga ctctgttgct 540 ggctcatctc gtgagtctac ccggaagggc agccgggcca gcttgggggc cctgtccctg 600 gaggcttatc tgaccacagg tgaagctgag acccgcgtcc ccactatgag gccgagcatg 660 tcgggactcc acctggtgaa gaggggacgg gaacacaaga agctggacct gcacagagac 720 tttaccgtgg cttctcccgc tgagtttgtc acacgctttg ggggggatcg ggtcatcgag 780 aaggtgctta ttgccaacaa cgggattgcc gctgtgaagt gcatgcgctc catccgcagg 840 tgggcctatg agatgttccg caacgagcgg gccatccggt ttgttcgcat ggtgaccccc 900 gaggacctta aggccaacgc agagtacatc aagatggcgg atcattacgg gcccgcccca 960 ggagggccca ataacaacaa ctatgccaac gtggagctga ttgtggacat tgccaagaga 1020 atcccgttgc aggcggtgtg ggctggctgg ggccatgctt tagaaaaccc taaacttccg 1080 gagctgctgt gcaagaatgg agttgctttc ttaggccctc ccaggttgag gccaatggtg 1140 ggtctaggag ataagatcgc ctccaccgtt gtcgcccaga cgctacaggt cccaaccctg 1200 cccaggagtg gaagcgccct gacagtggag tggacagaag atgatctgca gcagggaaaa 1260 agaatcagtg tcccagaaga tgtttatgac aagggttgcg tgaaagacgt agatgagggc 1320 ttggaggcag cagaaagaat tggttttcca ttgatgatca aagcttctga aggtggcgga 1380 gggaagggaa tccgggaaac tgagagtgcg gaggacttcc cgatcctttt cagacaagta 1440 cagagtgaga tcccaggctc gcccatcttt ctcatgaagc tggcccagca cgcccgtcac 1500 ctggaagttc agatcctcgc tgaccagtat gggaatgctg tgtctctgtt tggtcgcgac 1560 tgctccatcc agcggcggca tcagaagatc gttgaggaag caccggccac catcgcgccg 1620 ctggccatat tcgagttcat ggagcagtgt gccattcgcc tggccaagac cgtgggctat 1680 gtgagtgcag ggacagtgga atacctctat agtcaggatg gtagcttcca cttcttggag 1740 ctgaatcctc gcttgcaggt ggaacatccc tgcacagaaa tgattgctga cgttaatctg 1800 ccggccgccc agctacagat cgccatgggt gccccactgc accggctgaa agatatccgg 1860 cttctgtatg gagagtcacc ctggggagac tccccaattt cttttgaaaa ctcagctcat 1920 ctcccctgcc cccgaggcca cgtcattgcc accagaatca ccagcgaaaa cccagacgag 1980 ggttttaagc cgagctccgg gactgtccag gaactgaatt tccggagcag caagaacgtc 2040 tggggttact tcacggtggc cgctactgga ggcctgcacg agtttgcgat ttcccagttt 2100 gggcactgct tctcctgggg agagaaccgg aaagaggcca tttcgaacat ggtggtggct 2160 ttgaaggaac tgtccctccg aggcgacttt aggactaccg tggaatacct cattaacctc 2220 ctggagaccg agagcttcca gaacaactac atcgacaccg ggtggttgga ctacctcatt 2280 gctgagaaag tgcaaaagaa accgaatatc atgcttgggg tggtatgcgg ggcccttgaa 2340 cgtggagatg cgatgttcag aacgtgcatg acagatttct tacactccct ggaaaggggc 2400 caggtcctcc cagcggattc actactgaac ctcgtagatg tggaattaat ttacgagggt 2460 gtaaagtaca ttctaaaggt gacccggcag tctctgacca tgttcgttct catcatgaat 2520 ggctgccaca tcgagattga tgcccaccgg ctgaatgatg gggggctcct gctctcctac 2580 aatgggaaca gctacaccac ctacatgaag gaagaggttg acagttaccg taccatcggc 2640 aataagacgt gtgtttttga gaaggagaac gatcctacag tcctgagatc cccctcggct 2700 gggaagctga cacagatcac agtggaggat gggggccacg ttgaggctgg gagacgctac 2760 gctgagatgg aggtgatgaa gatgatcatg accctgaacg ttcaggaaag aggccgggtg 2820 aagtacatca agcgtccagg tgcggtgctg gaagcaggct gcgtggtggc caggctggag 2880 ctcgatgacc cttctaaagt ccacccggct gaaccgttca caggagaact ccctgcccag 2940 cagaacactg ccgacctcgg aaagaaactg cacagggtct tccacagcgt cctgggaagc 3000 ctcaccaacg tcatgagtgg cttttgtctg ccagagccgt tttttagcat aaagctgaag 3060 gagtgggtgc agaagctcat gatgaccctc cggcacccgt cactgctgct ggacgtgcag 3120 gagatcatga ccagtcgtgc aggccgcatc cccccccctg ttgagaagtc tgtccgcaag 3180 gtgatggccc agtatgccag caacatcacc tcggtgctgt gccagttccc cagccagcag 3240 atagccacca tcctggactg ccatgcagcc accctgcagc ggaaggctga tcgagaggtc 3300 ttcttcatca acacccagag catggtgcag ttggtccaga ggtaccgaag tggaatccgc 3360 ggtcatatga aaacagtggt gatcgatctc ttgagaagat acttgcgtgt tgagaccatt 3420 ttcggcaagg caagagatgc tgatgccaac tccagtggga tggtgggggg cgtgaggagc 3480 ctgagcttta cctctgtgtg ggtggttttg tctcccccag cccactacga caagtgtgtg 3540 ataaacctca gggaacagtt caagccagac atgtcccagg tgctggactg catcttctcc 3600 cacgcacagg tgaccaagaa gaaccagctg gtgatcatgt tgatcgatga gctgtgtggc 3660 ccagaccctt ccctgtcgga cgagctgatc tccatcctca acgagctcac tcagctgagc 3720 aaaagcgagc actgcaaagt ggccctcaga gcccggcaga tcctgatcgc ctccccctcc 3780 tacgagctgc ggcataacca ggtggagtcc attttcctgt ctgccattga catgtacggc 3840 caccagttct gccccgagaa cctccagaaa ttaatacttt cggaaacaac catcttcgac 3900 gtcctgaata ctttcttcta tcacgcaaac aaagtcgtgt gcatggcgtc cttggaggtt 3960 tacgtggggg gggcttacat cgcctatgtg ttaaacagcc tgcagcaccg gcagctcccg 4020 gacggcacct gcgtggtaga attccagttc atgctgccgt cctcccaccc aaaccggatg 4080 accgtgccca tcagcatcac caaccctgac ctgctgaggc acacgacaga gctcttcatg 4140 gacagcggct tctccccact gtgccagcgc atgggagcca tggtagcctt caggagattc 4200 gaggacttca ccagaaattt tgatgaagtc atctcttgct tcgccaacgt gccgaaagac 4260 ccccccctct tcagcgaggc ccgcacctcc ctatactccg aggatgactg caagagcctc 4320 agagaagagc ccatccacat tctgaatgtg tccatccagt gtgcggacca cctggaggat 4380 gaggcactgg tgccgatttt acgtacattc gtacagtcca agaaaaatat ccttgtggat 4440 tatggactcc gacgaatccc attcttgatt gcccaagaga aagaatttcc caagtttttc 4500 acattcagag caagagatga gtttgcagaa gatcgcattt accgtcactt ggaacctgcc 4560 ctggctttcc agctggaact caaccggatg cgtaacttcg atctgaccgc cgtgccctgt 4620 gccaaccaca agatgcacct ttacctgggt gctgccaagg tggaaggaag gtatgaagtg 4680 acggaccata ggttcttcat ccgtgccatc atcaggcact ctgacctgat cacaaaggaa 4740 gcctccttcg aatacctgca gaacgagggt gagcggctgc tcctggaggc catggacgag 4800 ctggaggtgg cgttcaataa caccaacgtg cgcaccgact gcaaccacat cttcctcaac 4860 ttcgtgccca ctgtcatcat ggaccccaac aagatcgagg agtccgtgcg ctacatggtt 4920 atgcgctacg gcagccggct gtggaaactc cgtgtgctac aggctgaggt caagatcaac 4980 atccgccaga ccaccaccgg cagtgccgtt cccatccgcc tgttcatcac caatgagtcg 5040 ggctactacc tggacatcag cctctacaaa gaagtgactg actccagatc tggaaatatc 5100 atgtttcact ccttcggcaa caagcaaggg ccccagcacg ggatgctgat caatactccc 5160 tacgtcacca aggatctgct ccaggccaag cgattccagg cccagaccct gggaaccacc 5220 tacatctatg acttcccgga aatgttcagg caggctctct ttaaactgtg gggctcccca 5280 gacaagtatc ccaaagacat cctgacatac actgaattag tgttggactc tcagggccag 5340 ctggtggaga tgaaccgact tcctggtgga aatgaggtgg gcatggtggc cttcaaaatg 5400 aggtttaaga cccaggagta cccggaagga cgggatgtga tcgtcatcgg caatgacatc 5460 acctttcgca ttggatcctt tggccctgga gaggaccttc tgtacctgcg ggcatccgag 5520 atggcccggg cagaggcgat tcccaaaatt tacgtggcag ccaacagtgg cgcccgtatt 5580 ggcatggcag aggagatcaa acacatgttc cacgtggctt gggtggaccc agaagacccc 5640 cacaaaggat ttaaatacct gtacctgact ccccaagact acaccagaat cagctccctg 5700 aactccgtcc actgtaaaca catcgaggaa ggaggagagt ccagatacat gatcacggat 5760 atcatcggga aggatgatgg cttgggcgtg gagaatctga ggggctcagg catgattgct 5820 ggggagtcct ctctggctta cgaagagatc gtcaccatta gcttggtgac ctgccgagcc 5880 attgggattg gggcctactt ggtgaggctg ggccagcgag tgatccaggt ggagaattcc 5940 cacatcatcc tcacaggagc aagtgctctc aacaaggtcc tgggaagaga ggtctacaca 6000 tccaacaacc agctgggtgg cgttcagatc atgcattaca atggtgtctc ccacatcacc 6060 gtgccagatg actttgaggg ggtttatacc atcctggagt ggctgtccta tatgccaaag 6120 gataatcaca gccctgtccc tatcatcaca cccactgacc ccattgacag agaaattgaa 6180 ttcctcccat ccagagctcc ctacgacccc cggtggatgc ttgcaggaag gcctcaccca 6240 actctgaagg gaacgtggca gagcggattc tttgaccacg gcagtttcaa ggaaatcatg 6300 gcaccctggg cgcagaccgt ggtgacagga cgagcaaggc ttggggggat tcccgtggga 6360 gtgattgctg tggagacacg gactgtggag gtggcagtcc ctgcagaccc tgccaacctg 6420 gattctgagg ccaagataat tcagcaggca ggacaggtgt ggttcccaga ctcagcctac 6480 aaaaccgccc aggccatcaa ggacttcaac cgggagaagt tgcccctgat gatctttgcc 6540 aactggaggg ggttctccgg tggcatgaaa gacatgtatg accaggtgct gaagtttgga 6600 gcctacatcg tggacggcct tagacaatac aaacagccca tcctgatcta tatccgccct 6660 atgcgggagc tccggggagg ctcctgggtg gtcatagatg ccaccatcaa cccgctgtgc 6720 atagaaatgt atgcagacaa agagagcagg ggtggtgttc tggaaccaga ggggacagtg 6780 gagattaagt tccgaaagga agatctgata aagtccatga gaaggatcga tccagcttac 6840 aagaagctca tggaacagct aggggaacct gatctctccg acaaggaccg aaaggacctg 6900 gagggccggc taaaggctcg cgaggacctg ctgctcccca tctaccacca ggtggcggtg 6960 cagttcgccg acttccatga cacacccggc cggatgctgg agaagggcgt catatctgac 7020 atcctggagt ggaagaccgc acgcaccttc ctgtattggc gtctgcgccg cctcctcctg 7080 gaggaccagg tcaagcagga gatcctgcag gccagcgggg agctgagtca cgtgcatatc 7140 cagtccatgc tgcgtcgctg gttcgtggag acggaggggg ctgtcaaggc ctacttgtgg 7200 gacaacaacc aggtggttgt gcagtggctg gaacagcact ggcaggcagg ggatggcccg 7260 cgctccacca tccgtgagaa catcacgtac ctgaagcacg actctgtcct caagaccatc 7320 cgaggcctgg ttgaagaaaa ccccgaggtg gccgtggact gtgtgatata cctgagccag 7380 cacatcagcc cagctgagcg ggcgcaggtc gttcacctgc tgtctaccat ggacagcccg 7440 gcctccacct ga 7452 // |
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