spacer
spacer
EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AAB00163; SV 1; linear; genomic DNA; STD; INV; 1833 BP.
XX
PA   L08489.1
XX
DE   Toxoplasma gondii dihydrofolate reductase-thymidylate synthase
XX
OS   Toxoplasma gondii
OC   Eukaryota; Alveolata; Apicomplexa; Coccidia; Eucoccidiorida; Eimeriorina;
OC   Sarcocystidae; Toxoplasma.
OX   NCBI_TaxID=5811;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1833
FT                   /organism="Toxoplasma gondii"
FT                   /strain="RH"
FT                   /mol_type="genomic DNA"
FT                   /dev_stage="tachyzoite"
FT                   /tissue_lib="Supercos"
FT   CDS             join(L08489.1:1396..1712,L08489.1:2203..2339,
FT                   L08489.1:2805..3136,L08489.1:3546..3795,
FT                   L08489.1:4290..4383,L08489.1:4763..4835,
FT                   L08489.1:5239..5380,L08489.1:5781..5873,
FT                   L08489.1:6500..6810,L08489.1:7342..7425)
FT                   /codon_start=1
FT                   /product="dihydrofolate reductase-thymidylate synthase"
FT                   /EC_number="1.5.1.3"
FT                   /EC_number="2.1.1.45"
FT                   /note="dihydrofolate reductase; bifunctional protein; the
FT                   251 amino acid DHFR domain is separated from the 289 amino
FT                   acidTS domain by a junctional domain of 70 amino acids"
FT                   /db_xref="GOA:Q07422"
FT                   /db_xref="HSSP:1HW3"
FT                   /db_xref="InterPro:IPR000398"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q07422"
FT                   /func_characterised="identical sequence"
FT                   /protein_id="AAB00163.1"
FT                   /translation="MQKPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPEE
FT                   ASRLNGWLPRKFAKTGDSGLPSPSVGKRFNAVVMGRKTWESMPRKFRPLVDRLNIVVSS
FT                   SLKEEDIAAEKPQAEGQQRVRVCASLPAALSLLEEEYKDSVDQIFVVGGAGLYEAALSL
FT                   GVASHLYITRVAREFPCDVFFPAFPGDDILSNKSTAAQAAAPAESVFVPFCPELGREKD
FT                   NEATYRPIFISKTFSDNGVPYDFVVLEKRRKTDDAATAEPSNAMSSLTSTRETTPVHGL
FT                   QAPSSAAAIAPVLAWMDEEDRKKREQKELIRAVPHVHFRGHEEFQYLDLIADIINNGRT
FT                   MDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKG
FT                   VKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNV
FT                   IQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLG
FT                   VPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNI
FT                   LNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV"
XX
SQ   Sequence 1833 BP; 439 A; 508 C; 497 G; 389 T; 0 other; 2716012319 CRC32;
     atgcagaaac cggtgtgtct ggtcgtcgcg atgaccccca agaggggcat cggcatcaac        60
     aacggcctcc cgtggcccca cttgaccaca gatttcaaac acttttctcg tgtgacaaaa       120
     acgacgcccg aagaagccag tcgcctgaac gggtggcttc ccaggaaatt tgcaaagacg       180
     ggcgactctg gacttccctc tccatcagtc ggcaagagat tcaacgccgt tgtcatggga       240
     cggaaaacct gggaaagcat gcctcgaaag tttagacccc tcgtggacag attgaacatc       300
     gtcgtttcct cttccctcaa agaagaagac attgcggcgg agaagcctca agctgaaggc       360
     cagcagcgcg tccgagtctg tgcttcactc ccagcagctc tcagccttct ggaggaagag       420
     tacaaggatt ctgtcgacca gatttttgtc gtgggaggag cgggactgta cgaggcagcg       480
     ctgtctctgg gcgttgcctc tcacctgtac atcacgcgtg tagcccgcga gtttccgtgc       540
     gacgttttct tccctgcgtt ccccggagat gacattcttt caaacaaatc aactgctgcg       600
     caggctgcag ctcctgccga gtctgtgttc gttccctttt gtccggagct cggaagagag       660
     aaggacaatg aagcgacgta tcgacccatc ttcatttcca agaccttctc agacaacggg       720
     gtaccctacg actttgtggt tctcgagaag agaaggaaga ctgacgacgc agccactgcg       780
     gaaccgagca acgcaatgag ctccttgacg tccacgaggg agacaactcc cgtgcacggg       840
     ttgcaggctc cttcttcggc cgcagccatt gccccggtgt tggcgtggat ggacgaagaa       900
     gaccggaaaa aacgcgagca aaaggaactg attcgggccg ttccgcatgt tcactttaga       960
     ggccatgaag aattccagta ccttgatctc attgccgaca ttattaacaa tggaaggaca      1020
     atggatgacc gaacgggcgt tggtgtcatc tccaaattcg gctgcactat gcgctactcg      1080
     ctggatcagg cctttccact tctcaccaca aagcgtgtgt tctggaaagg ggtcctcgaa      1140
     gagttgctgt ggttcattcg cggcgacacg aacgcaaacc atctttctga gaagggcgtg      1200
     aagatctggg acaagaatgt gacacgcgag ttcctcgatt cgcgcaatct cccccaccga      1260
     gaggtcggag acatcggccc gggctacggc ttccagtgga gacacttcgg cgcggcatac      1320
     aaagacatgc acacagacta cacagggcag ggcgtcgacc agctgaagaa tgtgatccag      1380
     atgctgagaa cgaatccaac agatcgtcgc atgctcatga ctgcctggaa tcctgcagcg      1440
     ctggacgaaa tggcgctgcc gccttgtcac ttgttgtgcc agttctacgt gaacgaccag      1500
     aaggagctgt cgtgcatcat gtatcagcgg tcgtgcgatg tcggcctcgg cgtccccttc      1560
     aacatcgctt cctattcgct tttgacgctc atggttgcac acgtctgcaa cctaaaacct      1620
     aaggagttca ttcacttcat ggggaacacg catgtctaca cgaaccatgt cgaggcttta      1680
     aaagagcagc tgcggagaga accgagaccg ttccccattg tgaacatcct caacaaggaa      1740
     cgcatcaagg aaatcgacga tttcaccgcc gaggattttg aggtcgtggg ctacgtcccg      1800
     cacggacgaa tccagatgga gatggctgtc tag                                   1833
//
spacer
spacer