 |
|
EBI DbfetchID AAA36527; SV 1; linear; mRNA; STD; HUM; 3429 BP. XX PA M64174.1 XX DE Homo sapiens (human) protein-tyrosine kinase XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606; XX FH Key Location/Qualifiers FH FT source 1..3429 FT /organism="Homo sapiens" FT /mol_type="mRNA" FT CDS M64174.1:76..3504 FT /codon_start=1 FT /gene="JAK1" FT /product="protein-tyrosine kinase" FT /db_xref="GDB:132236" FT /db_xref="GOA:P23458" FT /db_xref="HGNC:6190" FT /db_xref="InterPro:IPR008266" FT /db_xref="PDB:3EYG" FT /db_xref="UniProtKB/Swiss-Prot:P23458" FT /func_characterised="similar sequence" FT /protein_id="AAA36527.1" FT /translation="MAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTA FT EELCIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNW FT HGTNDNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRD FT PKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNL FT LTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLI FT SSENEMNWFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKDKK FT DEEKNKIREEWNNFSFFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDG FT YFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCT FT DFDNILMTVTCFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQ FT ILRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEH FT LGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSH FT KHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLE FT DKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVE FT DSKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLM FT TRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSRKKNQPTEVDPTHFEKRFLKRIRDLG FT EGHFGKVELCRYDPEDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKG FT ICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVH FT RDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYI FT ASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPN FT CPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK" XX SQ Sequence 3429 BP; 1011 A; 786 C; 856 G; 776 T; 0 other; 2805564140 CRC32; atggctttct gtgctaaaat gaggagctcc aagaagactg aggtgaacct ggaggcccct 60 gagccagggg tggaagtgat cttctatctg tcggacaggg agcccctccg gctgggcagt 120 ggagagtaca cagcagagga actgtgcatc agggctgcac aggcatgccg tatctctcct 180 ctttgtcaca acctctttgc cctgtatgac gagaacacca agctctggta tgctccaaat 240 cgcaccatca ccgttgatga caagatgtcc ctccggctcc actaccggat gaggttctat 300 ttcaccaatt ggcatggaac caacgacaat gagcagtcag tgtggcgtca ttctccaaag 360 aagcagaaaa atggctacga gaaaaaaaag attccagatg caacccctct ccttgatgcc 420 agctcactgg agtatctgtt tgctcaggga cagtatgatt tggtgaaatg cctggctcct 480 attcgagacc ccaagaccga gcaggatgga catgatattg agaacgagtg tctagggatg 540 gctgtcctgg ccatctcaca ctatgccatg atgaagaaga tgcagttgcc agaactgccc 600 aaggacatca gctacaagcg atatattcca gaaacattga ataagtccat cagacagagg 660 aaccttctca ccaggatgcg gataaataat gttttcaagg atttcctaaa ggaatttaac 720 aacaagacca tttgtgacag cagcgtgtcc acgcatgacc tgaaggtgaa atacttggct 780 accttggaaa ctttgacaaa acattacggt gctgaaatat ttgagacttc catgttactg 840 atttcatcag aaaatgagat gaattggttt cattcgaatg acggtggaaa cgttctctac 900 tacgaagtga tggtgactgg gaatcttgga atccagtgga ggcataaacc aaatgttgtt 960 tctgttgaaa aggaaaaaaa taaactgaag cggaaaaaac tggaaaataa agacaagaag 1020 gatgaggaga aaaacaagat ccgggaagag tggaacaatt tttcattctt ccctgaaatc 1080 actcacattg taataaagga gtctgtggtc agcattaaca agcaggacaa caagaaaatg 1140 gaactgaagc tctcttccca cgaggaggcc ttgtcctttg tgtccctggt agatggctac 1200 ttccggctca cagcagatgc ccatcattac ctctgcaccg acgtggcccc cccgttgatc 1260 gtccacaaca tacagaatgg ctgtcatggt ccaatctgta cagaatacgc catcaataaa 1320 ttgcggcaag aaggaagcga ggaggggatg tacgtgctga ggtggagctg caccgacttt 1380 gacaacatcc tcatgaccgt cacctgcttt gagaagtctg agcaggtgca gggtgcccag 1440 aagcagttca agaactttca gatcgaggtg cagaagggcc gctacagtct gcacggttcg 1500 gaccgcagct tccccagctt gggagacctc atgagccacc tcaagaagca gatcctgcgc 1560 acggataaca tcagcttcat gctaaaacgc tgctgccagc ccaagccccg agaaatctcc 1620 aacctgctgg tggctactaa gaaagcccag gagtggcagc ccgtctaccc catgagccag 1680 ctgagtttcg atcggatcct caagaaggat ctggtgcagg gcgagcacct tgggagaggc 1740 acgagaacac acatctattc tgggaccctg atggattaca aggatgacga aggaacttct 1800 gaagagaaga agataaaagt gatcctcaaa gtcttagacc ccagccacag ggatatttcc 1860 ctggccttct tcgaggcagc cagcatgatg agacaggtct cccacaaaca catcgtgtac 1920 ctctatggcg tctgtgtccg cgacgtggag aatatcatgg tggaagagtt tgtggaaggg 1980 ggtcctctgg atctcttcat gcaccggaaa agtgatgtcc ttaccacacc atggaaattc 2040 aaagttgcca aacagctggc cagtgccctg agctacttgg aggataaaga cctggtccat 2100 ggaaatgtgt gtactaaaaa cctcctcctg gcccgtgagg gaatcgacag tgagtgtggc 2160 ccattcatca agctcagtga ccccggcatc cccattacgg tgctgtctag gcaagaatgc 2220 attgaacgaa tcccatggat tgctcctgag tgtgttgagg actccaagaa cctgagtgtg 2280 gctgctgaca agtggagctt tggaaccacg ctctgggaaa tctgctacaa tggcgagatc 2340 cccttgaaag acaagacgct gattgagaaa gagagattct atgaaagccg gtgcaggcca 2400 gtgacaccat catgtaagga gctggctgac ctcatgaccc gctgcatgaa ctatgacccc 2460 aatcagaggc ctttcttccg agccatcatg agagacatta ataagcttga agagcagaat 2520 ccagatattg tttccagaaa aaaaaaccag ccaactgaag tggaccccac acattttgag 2580 aagcgcttcc taaagaggat ccgtgacttg ggagagggcc actttgggaa ggttgagctc 2640 tgcaggtatg accccgaaga caatacaggg gagcaggtgg ctgttaaatc tctgaagcct 2700 gagagtggag gtaaccacat agctgatctg aaaaaggaaa tcgagatctt aaggaacctc 2760 tatcatgaga acattgtgaa gtacaaagga atctgcacag aagacggagg aaatggtatt 2820 aagctcatca tggaatttct gccttcggga agccttaagg aatatcttcc aaagaataag 2880 aacaaaataa acctcaaaca gcagctaaaa tatgccgttc agatttgtaa ggggatggac 2940 tatttgggtt ctcggcaata cgttcaccgg gacttggcag caagaaatgt ccttgttgag 3000 agtgaacacc aagtgaaaat tggagacttc ggtttaacca aagcaattga aaccgataag 3060 gagtattaca ccgtcaagga tgaccgggac agccctgtgt tttggtatgc tccagaatgt 3120 ttaatgcaat ctaaatttta tattgcctct gacgtctggt cttttggagt cactctgcat 3180 gagctgctga cttactgtga ttcagattct agtcccatgg ctttgttcct gaaaatgata 3240 ggcccaaccc atggccagat gacagtcaca agacttgtga atacgttaaa agaaggaaaa 3300 cgcctgccgt gcccacctaa ctgtccagat gaggtttatc agcttatgag aaaatgctgg 3360 gaattccaac catccaatcg gacaagcttt cagaacctta ttgaaggatt tgaagcactt 3420 ttaaaataa 3429 // |
|