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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AAA30989; SV 1; linear; mRNA; STD; MAM; 951 BP.
XX
PA   L14950.1
XX
DE   Sus scrofa (pig) aldose reductase
XX
OS   Sus scrofa (pig)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..951
FT                   /organism="Sus scrofa"
FT                   /mol_type="mRNA"
FT                   /tissue_lib="Clontech"
FT                   /tissue_type="brain"
FT   CDS             L14950.1:20..970
FT                   /codon_start=1
FT                   /product="aldose reductase"
FT                   /EC_number="1.1.1.21"
FT                   /note="Arg268 is deemed essential by the authors (2). In
FT                   the humanenzyme, Arg268 was shown to be part of 22
FT                   hydrogen-bondingand salt-linking interactions between NADPH
FT                   and the enzyme(1).; putative"
FT                   /db_xref="GOA:P80276"
FT                   /db_xref="InterPro:IPR020471"
FT                   /db_xref="PDB:1AH0"
FT                   /db_xref="UniProtKB/Swiss-Prot:P80276"
FT                   /func_characterised="similar sequence"
FT                   /protein_id="AAA30989.1"
FT                   /translation="MASHLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDC
FT                   AHVYQNENEVGLGLQEKLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRNLKLDY
FT                   LDLYLIHWPTGFKPGKDPFPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFN
FT                   HLQVEKILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAK
FT                   PEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFEL
FT                   SPEDMNTLLSYNRNWRVCALMSCASHKDYPFHEEY"
XX
SQ   Sequence 951 BP; 231 A; 271 C; 263 G; 186 T; 0 other; 786736519 CRC32;
     atggccagcc acctcgtgct ctacaccggt gccaagatgc ccatcttggg gctgggcacc        60
     tggaagtccc ctccaggcaa agtgacagag gctgtgaagg tggccattga ccttgggtac       120
     cgccacattg actgtgccca tgtgtaccag aacgagaacg aggtggggct gggcctccag       180
     gagaagctcc aagggcaggt ggtgaagcgt gaggacctct tcatcgtcag taagctgtgg       240
     tgcacagacc atgagaagaa cctggtgaaa ggggcctgcc agacgaccct ccgcaacctg       300
     aagctggact acctggacct ctaccttatc cactggccca ctggcttcaa gcctggcaag       360
     gaccctttcc cgctggatgg cgacggcaac gtggttcctg atgagagcga ttttgtggag       420
     acgtgggagg ccatggagga gctggtggac gaagggctgg tgaaagccat tggcgtctcc       480
     aacttcaacc atctgcaagt ggagaagatc ttaaacaaac ctggcctgaa atacaagcca       540
     gccgttaacc agatcgaggt ccacccatac ctcactcagg agaagttaat cgaatactgc       600
     aagtccaaag gcatcgtggt gactgcctac agccccctcg gctctcccga caggccctgg       660
     gccaagcctg aggacccttc cctcctggag gaccccagga tcaaagcgat tgcagccaag       720
     tacaataaaa ccacagccca ggttctgatc cggttcccca tgcagaggaa cttgatcgtc       780
     atccccaagt ccgtgacgcc tgaacgcatt gccgagaact tccaggtctt tgactttgaa       840
     ctgagccctg aggatatgaa caccttactg agctacaaca ggaactggag ggtctgtgcc       900
     ttgatgagct gtgcctccca caaggattat ccctttcacg aggaatattg a                951
//
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