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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   IPI00292690.1         IPI;      PRT;  1102 AA.
AC   IPI00292690; IPI00011110; IPI00107369; IPI00216837; IPI00249310;
AC   IPI00373777;
DT   06-JUN-2003 (IPI Human rel. 2.20, Created)
DT   06-JUN-2003 (IPI Human rel. 2.20, Last sequence update)
DE   PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA
DE   ISOFORM.
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
CC   -!- GENE_LOCATION: Chr. 7:106505723-106547590:1.
DR   UniProtKB/Swiss-Prot; P48736; PK3CG_HUMAN; M.
DR   Vega; OTTHUMP00000025338; OTTHUMG00000023720; -.
DR   REFSEQ_REVIEWED; NP_002640; GI:21237725; -.
DR   UniProtKB/TrEMBL; A4D0Q6; A4D0Q6_HUMAN; -.
DR   UniProtKB/TrEMBL; A8K9G9; A8K9G9_HUMAN; -.
DR   ENSEMBL; ENSP00000352121; ENSG00000105851; -.
DR   ENSEMBL; ENSP00000392258; ENSG00000105851; -.
DR   ENSEMBL; ENSP00000419260; ENSG00000105851; -.
DR   H-InvDB; HIT000051470; HIX0025282; -.
DR   UniParc; UPI00000746B8; -; -.
DR   HGNC; 8978; PIK3CG; -.
DR   Entrez Gene; 5294; PIK3CG; -.
DR   UniGene; Hs.32942; -; -.
DR   CCDS; CCDS5739.1; -; -.
DR   trome; HTR009560; -; PRT.
DR   UTRdb; BB261755; U0035; 5'UTR.
DR   UTRdb; BB284432; -; 5'UTR.
DR   CleanEx; HS_PIK3CG; -; -.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR008973; C2_Ca/lipid-bd_reg_CaLB.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000403; PI3/4_kinase_cat.
DR   InterPro; IPR018936; PI3/4_kinase_CS.
DR   InterPro; IPR002420; PI3K_C2.
DR   InterPro; IPR000341; PI3K_ras_bd.
DR   InterPro; IPR001263; PI3Ka.
DR   InterPro; IPR015433; PI_Kinase.
DR   Pfam; PF00454; PI3_PI4_kinase; 1.
DR   Pfam; PF00792; PI3K_C2; 1.
DR   Pfam; PF00794; PI3K_rbd; 1.
DR   Pfam; PF00613; PI3Ka; 1.
DR   SMART; SM00142; PI3K_C2; 1.
DR   SMART; SM00144; PI3K_rbd; 1.
DR   SMART; SM00145; PI3Ka; 1.
DR   SMART; SM00146; PI3Kc; 1.
DR   PROSITE; PS00915; PI3_4_KINASE_1; 1.
DR   PROSITE; PS00916; PI3_4_KINASE_2; 1.
DR   PROSITE; PS50290; PI3_4_KINASE_3; 1.
DR   SUPERFAMILY; SSF48371; ARM-type_fold; 1.
DR   SUPERFAMILY; SSF49562; C2_CaLB; 1.
DR   SUPERFAMILY; SSF56112; Kinase_like; 1.
DR   PANTHER; PTHR10048; PI_Kinase; 1.
DR   GENE3D; G3DSA:1.10.1070.11; PI3/4_kinase_cat; 1.
DR   GENE3D; G3DSA:1.25.40.70; PI3Ka; 1.
SQ   SEQUENCE   1102 AA;  126454 MW;  EF2B1A0E1CBEF406 CRC64;
     MELENYKQPV VLREDNCRRR RRMKPRSAAA SLSSMELIPI EFVLPTSQRK CKSPETALLH
     VAGHGNVEQM KAQVWLRALE TSVAADFYHR LGPHHFLLLY QKKGQWYEIY DKYQVVQTLD
     CLRYWKATHR SPGQIHLVQR HPPSEESQAF QRQLTALIGY DVTDVSNVHD DELEFTRRGL
     VTPRMAEVAS RDPKLYAMHP WVTSKPLPEY LWKKIANNCI FIVIHRSTTS QTIKVSPDDT
     PGAILQSFFT KMAKKKSLMD IPESQSEQDF VLRVCGRDEY LVGETPIKNF QWVRHCLKNG
     EEIHVVLDTP PDPALDEVRK EEWPLVDDCT GVTGYHEQLT IHGKDHESVF TVSLWDCDRK
     FRVKIRGIDI PVLPRNTDLT VFVEANIQHG QQVLCQRRTS PKPFTEEVLW NVWLEFSIKI
     KDLPKGALLN LQIYCGKAPA LSSKASAESP SSESKGKVQL LYYVNLLLID HRFLLRRGEY
     VLHMWQISGK GEDQGSFNAD KLTSATNPDK ENSMSISILL DNYCHPIALP KHQPTPDPEG
     DRVRAEMPNQ LRKQLEAIIA TDPLNPLTAE DKELLWHFRY ESLKHPKAYP KLFSSVKWGQ
     QEIVAKTYQL LARREVWDQS ALDVGLTMQL LDCNFSDENV RAIAVQKLES LEDDDVLHYL
     LQLVQAVKFE PYHDSALARF LLKRGLRNKR IGHFLFWFLR SEIAQSRHYQ QRFAVILEAY
     LRGCGTAMLH DFTQQVQVIE MLQKVTLDIK SLSAEKYDVS SQVISQLKQK LENLQNSQLP
     ESFRVPYDPG LKAGALAIEK CKVMASKKKP LWLEFKCADP TALSNETIGI IFKHGDDLRQ
     DMLILQILRI MESIWETESL DLCLLPYGCI STGDKIGMIE IVKDATTIAK IQQSTVGNTG
     AFKDEVLNHW LKEKSPTEEK FQAAVERFVY SCAGYCVATF VLGIGDRHND NIMITETGNL
     FHIDFGHILG NYKSFLGINK ERVPFVLTPD FLFVMGTSGK KTSPHFQKFQ DICVKAYLAL
     RHHTNLLIIL FSMMLMTGMP QLTSKEDIEY IRDALTVGKN EEDAKKYFLD QIEVCRDKGW
     TVQFNWFLHL VLGIKQGEKH SA
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