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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   IPI00219250.1         IPI;      PRT;   754 AA.
AC   IPI00219250; IPI00006021; IPI00107821;
DT   09-APR-2003 (IPI Human rel. 2.18, Created)
DT   09-APR-2003 (IPI Human rel. 2.18, Last sequence update)
DE   ISOFORM 1 OF DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED
DE   KINASE 1A.
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
CC   -!- GENE_LOCATION: Chr. 21:38739236-38887680:1.
DR   UniProtKB/Swiss-Prot; Q13627-2; DYR1A_HUMAN; M.
DR   Vega; OTTHUMP00000109091; OTTHUMG00000086657; -.
DR   REFSEQ_REVIEWED; NP_569120; GI:18765752; -.
DR   UniProtKB/TrEMBL; B4DX02; B4DX02_HUMAN; -.
DR   UniProtKB/TrEMBL; O60770; O60770_HUMAN; -.
DR   UniProtKB/TrEMBL; O94789; O94789_HUMAN; -.
DR   UniProtKB/TrEMBL; Q15446; Q15446_HUMAN; -.
DR   ENSEMBL; ENSP00000340373; ENSG00000157540; -.
DR   UniParc; UPI000002A87A; -; -.
DR   HGNC; 3091; DYRK1A; -.
DR   Entrez Gene; 1859; DYRK1A; -.
DR   UniGene; Hs.368240; -; -.
DR   UniGene; Hs.714829; -; -.
DR   CCDS; CCDS13653.1; -; -.
DR   UTRdb; BB009585; -; 5'UTR.
DR   UTRdb; BB009673; -; 5'UTR.
DR   UTRdb; BB043166; -; 5'UTR.
DR   UTRdb; BB052013; -; 5'UTR.
DR   UTRdb; BB057073; -; 5'UTR.
DR   UTRdb; BB063395; -; 5'UTR.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR017442; Se/Thr_prot_kinase-like_dom.
DR   InterPro; IPR008271; Ser/Thr_prot_kinase_AS.
DR   InterPro; IPR002290; Ser/Thr_prot_kinase_dom.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR   SUPERFAMILY; SSF56112; Kinase_like; 1.
SQ   SEQUENCE   754 AA;  84556 MW;  59518E25F1D4FF96 CRC64;
     MHTGGETSAC KPSSVRLAPS FSFHAAGLQM AGQMPHSHQY SDRRQPNISD QQVSALSYSD
     QIQQPLTNQR RMPQTFRDPA TAPLRKLSVD LIKTYKHINE VYYAKKKRRH QQGQGDDSSH
     KKERKVYNDG YDDDNYDYIV KNGEKWMDRY EIDSLIGKGS FGQVVKAYDR VEQEWVAIKI
     IKNKKAFLNQ AQIEVRLLEL MNKHDTEMKY YIVHLKRHFM FRNHLCLVFE MLSYNLYDLL
     RNTNFRGVSL NLTRKFAQQM CTALLFLATP ELSIIHCDLK PENILLCNPK RSAIKIVDFG
     SSCQLGQRIY QYIQSRFYRS PEVLLGMPYD LAIDMWSLGC ILVEMHTGEP LFSGANEVDQ
     MNKIVEVLGI PPAHILDQAP KARKFFEKLP DGTWNLKKTK DGKREYKPPG TRKLHNILGV
     ETGGPGGRRA GESGHTVADY LKFKDLILRM LDYDPKTRIQ PYYALQHSFF KKTADEGTNT
     SNSVSTSPAM EQSQSSGTTS STSSSSGGSS GTSNSGRARS DPTHQHRHSG GHFTAAVQAM
     DCETHSPQVR QQFPAPLGWS GTEAPTQVTV ETHPVQETTF HVAPQQNALH HHHGNSSHHH
     HHHHHHHHHH GQQALGNRTR PRVYNSPTNS SSTQDSMEVG HSHHSMTSLS SSTTSSSTSS
     SSTGNQGNQA YQNRPVAANT LDFGQNGAMD VNLTVYSNPR QETGIAGHPT YQFSANTGPA
     HYMTEGHLTM RQGADREESP MTGVCVQQSP VASS
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