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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   IPI00027725.1         IPI;      PRT;   377 AA.
AC   IPI00027725; IPI00069447; IPI00181167;
DT   01-OCT-2001 (IPI Human rel. 2.00, Created)
DT   01-OCT-2001 (IPI Human rel. 2.00, Last sequence update)
DE   CASPASE-4.
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
CC   -!- GENE_LOCATION: Chr. 11:104813594-104840163:-1.
DR   UniProtKB/Swiss-Prot; P49662; CASP4_HUMAN; M.
DR   REFSEQ_REVIEWED; NP_001216; GI:4502577; -.
DR   UniProtKB/TrEMBL; A2NHL8; A2NHL8_HUMAN; -.
DR   UniProtKB/TrEMBL; B3KPZ9; B3KPZ9_HUMAN; -.
DR   UniProtKB/TrEMBL; B4E2D2; B4E2D2_HUMAN; -.
DR   ENSEMBL; ENSP00000388566; ENSG00000196954; -.
DR   H-InvDB; HIT000292350; HIX0010073; -.
DR   UniParc; UPI000003AEFA; -; -.
DR   HGNC; 1505; CASP4; -.
DR   Entrez Gene; 837; CASP4; -.
DR   UniGene; Hs.138378; -; -.
DR   CCDS; CCDS8327.1; -; -.
DR   trome; HTR000140; -; PRT.
DR   UTRdb; BB064310; -; 5'UTR.
DR   UTRdb; BB064311; -; 5'UTR.
DR   UTRdb; CC082819; U0024; 3'UTR.
DR   CleanEx; HS_CASP4; -; -.
DR   InterPro; IPR001315; CARD.
DR   InterPro; IPR017350; Caspase_IL-1_beta.
DR   InterPro; IPR011029; DEATH-like.
DR   InterPro; IPR011600; Pept_C14_cat.
DR   InterPro; IPR001309; Pept_C14_ICE_p20.
DR   InterPro; IPR016129; Pept_C14_ICE_p20_AS.
DR   InterPro; IPR002138; Pept_C14_p10.
DR   InterPro; IPR002398; Pept_C14_p45.
DR   InterPro; IPR015917; Pept_C14_p45_core.
DR   Pfam; PF00619; CARD; 1.
DR   Pfam; PF00656; Peptidase_C14; 1.
DR   PRINTS; PR00376; IL1BCENZYME.
DR   SMART; SM00114; CARD; 1.
DR   SMART; SM00115; CASc; 1.
DR   PROSITE; PS50209; CARD; 1.
DR   PROSITE; PS01122; CASPASE_CYS; 1.
DR   PROSITE; PS01121; CASPASE_HIS; 1.
DR   PROSITE; PS50207; CASPASE_P10; 1.
DR   PROSITE; PS50208; CASPASE_P20; 1.
DR   SUPERFAMILY; SSF47986; DEATH_like; 1.
DR   PANTHER; PTHR10454; Pept_C14_p45; 1.
DR   GENE3D; G3DSA:1.10.533.10; DEATH_like; 1.
DR   PIRSF; PIRSF038001; Caspase_ICE; 1.
SQ   SEQUENCE   377 AA;  43262 MW;  DC7CCEC6E9D483EB CRC64;
     MAEGNHRKKP LKVLESLGKD FLTGVLDNLV EQNVLNWKEE EKKKYYDAKT EDKVRVMADS
     MQEKQRMAGQ MLLQTFFNID QISPNKKAHP NMEAGPPESG ESTDALKLCP HEEFLRLCKE
     RAEEIYPIKE RNNRTRLALI ICNTEFDHLP PRNGADFDIT GMKELLEGLD YSVDVEENLT
     ARDMESALRA FATRPEHKSS DSTFLVLMSH GILEGICGTV HDEKKPDVLL YDTIFQIFNN
     RNCLSLKDKP KVIIVQACRG ANRGELWVRD SPASLEVASS QSSENLEEDA VYKTHVEKDF
     IAFCSSTPHN VSWRDSTMGS IFITQLITCF QKYSWCCHLE EVFRKVQQSF ETPRAKAQMP
     TIERLSMTRY FYLFPGN
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