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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   IPI00011518.1         IPI;      PRT;   501 AA.
AC   IPI00011518; IPI00027546; IPI00027548; IPI00027551; IPI00033432;
AC   IPI00098718; IPI00184003; IPI00384501; IPI00644105;
DT   01-OCT-2001 (IPI Human rel. 2.00, Created)
DT   01-OCT-2001 (IPI Human rel. 2.00, Last sequence update)
DE   ISOFORM A OF BETA-SECRETASE 1.
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
CC   -!- GENE_LOCATION: Chr. 11:117156417-117186972:-1.
DR   UniProtKB/Swiss-Prot; P56817-1; BACE1_HUMAN; M.
DR   REFSEQ_REVIEWED; NP_036236; GI:6912266; -.
DR   UniProtKB/TrEMBL; A0M8W7; A0M8W7_HUMAN; -.
DR   UniProtKB/TrEMBL; B3KQJ4; B3KQJ4_HUMAN; -.
DR   UniProtKB/TrEMBL; B7Z3Z4; B7Z3Z4_HUMAN; -.
DR   UniProtKB/TrEMBL; Q5W9H2; Q5W9H2_HUMAN; -.
DR   UniProtKB/TrEMBL; Q8IYC8; Q8IYC8_HUMAN; -.
DR   ENSEMBL; ENSP00000318585; ENSG00000186318; -.
DR   H-InvDB; HIT000073772; HIX0010165; -.
DR   UniParc; UPI0000048186; -; -.
DR   HGNC; 933; BACE1; -.
DR   Entrez Gene; 23621; BACE1; -.
DR   UniGene; Hs.504003; -; -.
DR   CCDS; CCDS8383.1; -; -.
DR   UTRdb; BB071032; -; 5'UTR.
DR   UTRdb; BB154313; -; 5'UTR.
DR   UTRdb; BB266404; -; 5'UTR.
DR   UTRdb; BB284554; U0011; 5'UTR.
DR   UTRdb; BB329396; -; 5'UTR.
DR   UTRdb; BB344844; -; 5'UTR.
DR   UTRdb; BB400743; -; 5'UTR.
DR   UTRdb; CC262026; -; 3'UTR.
DR   InterPro; IPR009119; Pept_A1_BACE.
DR   InterPro; IPR009120; Pept_A1_BACE1.
DR   InterPro; IPR001461; Peptidase_A1.
DR   InterPro; IPR001969; Peptidase_aspartic_AS.
DR   InterPro; IPR009007; Peptidase_aspartic_catalytic.
DR   Pfam; PF00026; Asp; 1.
DR   PRINTS; PR01816; BACE1.
DR   PRINTS; PR01815; BACEFAMILY.
DR   PRINTS; PR00792; PEPSIN.
DR   PROSITE; PS00141; ASP_PROTEASE; 1.
DR   SUPERFAMILY; SSF50630; Pept_Aspartic; 1.
DR   PANTHER; PTHR13683; Peptidase_A1; 1.
DR   GENE3D; G3DSA:2.40.70.10; Pept_Aspartc_cat; 2.
SQ   SEQUENCE   501 AA;  55764 MW;  377CE4C824ACEF05 CRC64;
     MAQALPWLLL WMGAGVLPAH GTQHGIRLPL RSGLGGAPLG LRLPRETDEE PEEPGRRGSF
     VEMVDNLRGK SGQGYYVEMT VGSPPQTLNI LVDTGSSNFA VGAAPHPFLH RYYQRQLSST
     YRDLRKGVYV PYTQGKWEGE LGTDLVSIPH GPNVTVRANI AAITESDKFF INGSNWEGIL
     GLAYAEIARP DDSLEPFFDS LVKQTHVPNL FSLQLCGAGF PLNQSEVLAS VGGSMIIGGI
     DHSLYTGSLW YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK
     VFEAAVKSIK AASSTEKFPD GFWLGEQLVC WQAGTTPWNI FPVISLYLMG EVTNQSFRIT
     ILPQQYLRPV EDVATSQDDC YKFAISQSST GTVMGAVIME GFYVVFDRAR KRIGFAVSAC
     HVHDEFRTAA VEGPFVTLDM EDCGYNIPQT DESTLMTIAY VMAAICALFM LPLCLMVCQW
     RCLRCLRQQH DDFADDISLL K
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