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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   AY036464; SV 1; linear; genomic DNA; STD; VRL; 297 BP.
XX
AC   AY036464;
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DT   16-AUG-2001 (Rel. 68, Created)
DT   16-APR-2005 (Rel. 83, Last updated, Version 2)
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DE   HIV-1 isolate NL4-3 resting pha 12hrs clone 2 from USA protease (pol) gene,
DE   partial cds.
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KW   .
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OS   Human immunodeficiency virus 1
OC   Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae;
OC   Lentivirus; Primate lentivirus group.
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RN   [1]
RP   1-297
RX   DOI; 10.1128/JVI.75.17.7973-7986.2001.
RX   PUBMED; 11483742.
RA   Janini M., Rogers M., Birx D.R., McCutchan F.E.;
RT   "Human immunodeficiency virus type 1 DNA sequences genetically damaged by
RT   hypermutation are often abundant in patient peripheral blood mononuclear
RT   cells and may be generated during near-simultaneous infection and
RT   activation of CD4(+) T cells";
RL   J. Virol. 75(17):7973-7986(2001).
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RN   [2]
RP   1-297
RA   Janini M., Rogers M., Birx D.R., McCutchan F.E.;
RT   ;
RL   Submitted (16-MAY-2001) to the EMBL/GenBank/DDBJ databases.
RL   Retrovirology, Henry M. Jackson Foundation, 1 Taft Court, Rockville, MD
RL   20850, USA
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FH   Key             Location/Qualifiers
FH
FT   source          1..297
FT                   /organism="Human immunodeficiency virus 1"
FT                   /isolate="NL4-3 resting pha 12hrs"
FT                   /mol_type="genomic DNA"
FT                   /country="USA"
FT                   /clone="2"
FT                   /proviral
FT                   /note="in vitro virus propagation; sequences obtained after
FT                   HIV-1 infection of unstimulated CD4+ T-cells using cloned
FT                   NL4-3 virus stocks; cells were PHA stimulated 24 hours
FT                   after the 2 hour infection period; cells were collected  6,
FT                   12, 24, 48, 72 hours after activation"
FT                   /db_xref="taxon:11676"
FT   CDS             <1..>297
FT                   /codon_start=1
FT                   /gene="pol"
FT                   /product="protease"
FT                   /db_xref="GOA:Q90EE8"
FT                   /db_xref="HSSP:1PRO"
FT                   /db_xref="InterPro:IPR001969"
FT                   /db_xref="InterPro:IPR001995"
FT                   /db_xref="InterPro:IPR009007"
FT                   /db_xref="InterPro:IPR018061"
FT                   /db_xref="UniProtKB/TrEMBL:Q90EE8"
FT                   /protein_id="AAK67562.1"
FT                   /translation="PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPK
FT                   MIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF"
XX
SQ   Sequence 297 BP; 109 A; 48 C; 66 G; 74 T; 0 other;
     cctcaaatca ctctttggca acgacccctc gtcacaataa agataggggg gcaattaaag        60
     gaagctctat tagatacagg agcagatgat acagtattag aagaaatgaa tttgccagga       120
     agatggaaac caaaaatgat agggggaatt ggaggtttta tcaaagtaag acagtatgat       180
     cagatactca tagaaatctg cggacataaa gctataggta cagtattagt aggacctaca       240
     cctgtcaaca taattggaag aaatctgttg actcagattg gctgcacttt aaatttt          297
//
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