1.0 1.0 UniProt G2K_P10815 1.0 S-phasePromotingFactor ubiquitinProtease1 1.0 1.0 ACTIVATION 1.0 ACTIVATION TotalRum1 UbE mediated degradation of Cdc13_Cdc2 in Rum1_Cdc13_P-Cdc2 RIGHT_TO_LEFT true Rum1 degradation by SPF 1.0 1.0 Rum1 creation Cdc13 degradation in Rum1_Cdc13_Cdc2 RIGHT_TO_LEFT true 1.0 bioSource BoundIntermediaryEnzyme Gene Ontology G2R_Creation_GO:0006461 1.0 Cdc13_P-Cdc2 1.0 Cdc13 degradation in Rum1_Cdc13_P-Cdc2 RIGHT_TO_LEFT true UniProt Wee1_P30290 1.0 1.0 1.0 Cell Rum1 degradation in solution 1.0 Gene Ontology Cdc2Phos_GO:0006468 ACTIVATION FreeRum1 Gene Ontology GO:0000278 BoundUbiquitinProtease1 1.0 1.0 Cdc13_Cdc2 creation LEFT_TO_RIGHT true Gene Ontology Rum1DegInG2R_GO:0030163 Cdc25 production & degradation ACTIVATION ACTIVATION 1.0 binding of Rum1 with Cdc13_P-Cdc2 Rum1 degradation in Rum1_Cdc13_Cdc2 ACTIVATION ACTIVATION Wee1 production & degradation Gene Ontology G2K_dissoc_GO:0008054 1.0 Wee1 1.0 Rum1 degradation in Rum1_Cdc13_P-Cdc2 PubMed 9256450 1.0 IE production & degradation ACTIVATION 1.0 1.0 UniProt G2K_P04551 IntermediaryEnzyme BoundCdc25 BoundWee1 Cdc2 phosphorylation Cdc13 degradation in Cdc13_Cdc2 RIGHT_TO_LEFT true 1.0 binding of Rum1 with Cdc13_Cdc2 1.0 UbE mediated degradation of Cdc13_Cdc2 in Rum1_Cdc13_Cdc2 RIGHT_TO_LEFT true Cig2_Cdc2 creation LEFT_TO_RIGHT true BioPAX Level3 file automatically generated by SBML2BioPAX-1.3.2 (19-May-2012), Computational Systems Neurobiology Group - EMBL-EBI, UK UniProt R_P40380 TotalCdc13 1.0 Taxonomy 4896 1.0 1.0 UbE2 production & degradation Enzyme Nomenclature Cdc2Phos_2.7.10.2 Binding of Rum1 to Cig2_Cdc2 UniProt Wee1_P07527 ACTIVATION BoundUbiquitinProtease2 1.0 1.0 1.0 1.0 Gene Ontology Cell_GO:0005623 1.0 Cdc13_P-Cdc2_Rum1 Cdc13_Cdc2_Rum1 Cdc25 ACTIVATION Cig2 degradation in Cig2_Cdc2 RIGHT_TO_LEFT true ubiquitinProtease2 1.0 Cdc13_Cdc2 1.0 Cig2 degradation in Rum1_Cig2_Cdc2 RIGHT_TO_LEFT true Rum1 degradation in Rum1_Cig2_Cdc2 1.0 1.0 UbE production & degradation 1.0 1.0 1.0 1.0 ACTIVATION 1.0 1.0 ACTIVATION ACTIVATION Cig2_Cdc2_Rum1 1.0 TotalCig2 M-phasePromotingFactor UniProt G1K_P36630 1.0 Cdc13 degradation in Cdc13_P-Cdc2 RIGHT_TO_LEFT true Cig2_Cdc2 UniProt Cdc25_P06652