Sheppard2018 - Toxic Activity of K28 Killer Yeast Protein
A deterministic model built in COPASI simulating the toxic activity of the K28 toxin produced by Saccharomyces cerevisiae. It simulates the kinetics of inoculating a susceptible population of cells with the toxin and can be used to display the toxin acting via its primary mechanistic pathway at high concentrations or the secondary action pathway, via induced apoptosis, seen at low concentrations.
- Dynamic modelling of the killing mechanism of action by virus-infected yeasts
- J. R. Soc. Interface , 3/ 2019
- Department of Chemical Engineering and Biotechnology University of Cambridge
Rahuman Sheriff, Sean Sheppard
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