BioModels is a repository of mathematical models of biological and biomedical systems. It hosts a vast selection of existing literature-based physiologically and pharmaceutically relevant mechanistic models in standard formats. Our mission is to provide the systems modelling community with reproducible, high-quality, freely-accessible models published in the scientific literature. More information about using BioModels such as model submission, update, publication can be found in the FAQ.

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Manually Curated

1,000 models

Non-curated

1,315 models

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833 models

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1,132 classes
1,000 models
1,315 models
833 models
1,132 classes

Model of The Month

September,  2020

SIDARTHE model of COVID-19 transmission in Italy

Modified SEIR model of COVID-19 transmission in Italy quantifying the effects of lockdown measures on the process

Model(s) associated with this Model of the Month: BIOMD0000000955 

Last updated by: Kausthubh Ramachandran


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Recently published

  •   Signaling class 3
    Submitter: uddipan sarma | Published date: 2021-02-25
    Publication: Cell-specific responses to the cytokine TGFb are determined by variability in protein levels., Molecular systems biology (2018)
  •   Strasen2018 – TGFβ SMAD Signalling Class 4
    Submitter: Rahuman Sheriff | Published date: 2021-02-25
    Publication: Cell-specific responses to the cytokine TGFb are determined by variability in protein levels., Molecular systems biology (2018)
  •   Delattre2020 - SARS-CoV-2-infected human lung cell
    Submitter: hadrien delattre | Published date: 2021-03-02
    Publication: Inhibiting the reproduction of SARS-CoV-2 through perturbations in human lung cell metabolic network, Life Science Alliance (2020)
  •   den Breems2015 - macrophage in cancer
    Submitter: Jinghao Men | Published date: 2021-03-05
    Publication: The re-polarisation of M2 and M1 macrophages and its role on cancer outcomes., Journal of theoretical biology (2016)
  •   Intoslami2015 - Th17 core network model
    Submitter: Krishna Kumar Tiwari | Published date: 2021-02-26
    Publication: Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data., BMC systems biology (2015)
  •   Signaling_class_5
    Submitter: uddipan sarma | Published date: 2021-02-25
    Publication: Cell-specific responses to the cytokine TGFb are determined by variability in protein levels., Molecular systems biology (2018)
  •   Signaling_class_6
    Submitter: uddipan sarma | Published date: 2021-02-25
    Publication: Cell-specific responses to the cytokine TGFb are determined by variability in protein levels., Molecular systems biology (2018)

How to cite BioModels

Rahuman S Malik-Sheriff, Mihai Glont, Tung V N Nguyen, Krishna Tiwari, Matthew G Roberts, Ashley Xavier, Manh T Vu, Jinghao Men, Matthieu Maire, Sarubini Kananathan, Emma L Fairbanks, Johannes P Meyer, Chinmay Arankalle, Thawfeek M Varusai, Vincent Knight-Schrijver, Lu Li, Corina Dueñas-Roca, Gaurhari Dass, Sarah M Keating, Young M Park, Nicola Buso, Nicolas Rodriguez, Michael Hucka, and Henning Hermjakob
Nucl. Acids Res. 2020
Mihai Glont, Tung V N Nguyen, Martin Graesslin, Robert Hälke, Raza Ali, Jochen Schramm, Sarala M Wimalaratne, Varun B Kothamachu, Nicolas Rodriguez, Maciej J Swat, Jurgen Eils, Roland Eils, Camille Laibe, Rahuman S Malik-Sheriff, Vijayalakshmi Chelliah, Nicolas Le Novère, and Henning Hermjakob
Nucl. Acids Res. 2018
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