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Diseases related models

 

List of disease related literature based models (from the curated and non-curated branches).

Those models have been annotated with terms from the Human Disease Ontology, Online Mendelian Inheritance in Man or International Classification of Diseases.

Human Disease Ontology

Andersen-Tawil syndrome

Model name Publication Status  
Clancy2001_Kchannel (BIOMD0000000121) Cellular consequences of HERG mutations in the lon [...] curated model icon download icon

Brugada syndrome

Model name Publication Status  
Clancy2002_CardiacSodiumChannel_WT (BIOMD0000000126) Na(+) channel mutation that causes both Brugada an [...] curated model icon download icon

Clostridium difficile colitis

Model name Publication Status  
Leber2015 - Mucosal immunity and gut microbiome interaction during C. difficile infection (BIOMD0000000583) Systems Modeling of Interactions between Mucosal I [...] curated model icon download icon

Crohn's disease

Model name Publication Status  
Dwivedi2014 - Crohns IL6 Disease model - Anti-IL6 Antibody (BIOMD0000000535) A multiscale model of interleukin-6-mediated immun [...] curated model icon download icon
Dwivedi2014 - Crohns IL6 Disease model - Anti-IL6R Antibody (BIOMD0000000537) A multiscale model of interleukin-6-mediated immun [...] curated model icon download icon
Dwivedi2014 - Crohns IL6 Disease model - sgp130 activity (BIOMD0000000536) A multiscale model of interleukin-6-mediated immun [...] curated model icon download icon
Dwivedi2014 - Healthy Volunteer IL6 Model (BIOMD0000000534) A multiscale model of interleukin-6-mediated immun [...] curated model icon download icon

DOID: 0060075

Model name Publication Status  
Mufudza2012 - Estrogen effect on the dynamics of breast cancer (BIOMD0000000642) Assessing the effects of estrogen on the dynamics [...] curated model icon download icon

DOID:10652

Model name Publication Status  
Auer2010 - Correlation between lag time and aggregation rate in protein aggregation (BIOMD0000000555) Insight into the correlation between lag time and [...] curated model icon download icon
Crespo2012 - Kinetics of Amyloid Fibril Formation (BIOMD0000000531) A generic crystallization-like model that describe [...] curated model icon download icon
Das2010 - Effect of a gamma-secretase inhibitor on Amyloid-beta dynamics (BIOMD0000000551) Modeling effect of a γ-secretase inhibitor on amyl [...] curated model icon download icon
Ehrenstein1997 - The choline-leakage hypothesis in Alzheimer's disease (BIOMD0000000553) The choline-leakage hypothesis for the loss of ace [...] curated model icon download icon
Ehrenstein2000 - Positive-Feedback model for the loss of acetylcholine in Alzheimer's disease (BIOMD0000000552) A positive-feedback model for the loss of acetylch [...] curated model icon download icon
Krohn2011 - Cerebral amyloid-β proteostasis regulated by membrane transport protein ABCC1 (BIOMD0000000618) Cerebral amyloid-? proteostasis is regulated by th [...] curated model icon download icon
Lockwood2006_PKPD_AlzheimersDisease (MODEL1006230054) Application of clinical trial simulation to compar [...] non-curated model icon download icon
Martins2013 - True and apparent inhibition of amyloid fribril formation (BIOMD0000000561) True and apparent inhibition of amyloid fibril for [...] curated model icon download icon
Morris2008 - Fitting protein aggregation data via F-W 2-step mechanism (BIOMD0000000567) Fitting neurological protein aggregation kinetic d [...] curated model icon download icon
Ortega2013 - Interplay between secretases determines biphasic amyloid-beta level (BIOMD0000000556) Interplay between α-, β-, and γ-secretases determi [...] curated model icon download icon
Proctor2005 - Actions of chaperones and their role in ageing (BIOMD0000000091) Modelling the actions of chaperones and their role [...] curated model icon download icon
Proctor2010 - a link between GSK3 and p53 in Alzheimer's Disease (BIOMD0000000286) GSK3 and p53 - is there a link in Alzheimer's dise [...] curated model icon download icon
Proctor2012 - Role of Amyloid-beta dimers in aggregation formation (BIOMD0000000462) Aggregation, impaired degradation and immunization [...] curated model icon download icon
Proctor2013 - Effect of Aβ immunisation in Alzheimer's disease (deterministic version) (BIOMD0000000488) Investigating interventions in Alzheimer's disease [...] curated model icon download icon
Proctor2013 - Effect of Aβ immunisation in Alzheimer's disease (stochastic version) (BIOMD0000000634) Investigating interventions in Alzheimer's disease [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon
Steckmann2012 - Amyloid beta-protein fibrillogenesis (kinetics of secondary structure conversion) (BIOMD0000000533) Kinetics of peptide secondary structure conversion [...] curated model icon download icon
Vazquez2014 - Chemical inhibition from amyloid protein aggregation kinetics (BIOMD0000000532) Modeling of chemical inhibition from amyloid prote [...] curated model icon download icon
Walsh2014 - Inhibition kinetics of DAPT on APP Cleavage (BIOMD0000000617) Are improper kinetic models hampering drug develop [...] curated model icon download icon
Winter2017 - Brain Energy Metabolism with PPP (BIOMD0000000627) Mathematical analysis of the influence of brain me [...] curated model icon download icon
Yuraszeck2010 - Vulnerabilities in the Tau Network in Tau Pathophysiology (BIOMD0000000542) Vulnerabilities in the tau network and the role of [...] curated model icon download icon

DOID:12858

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon
Morris2008 - Fitting protein aggregation data via F-W 2-step mechanism (BIOMD0000000567) Fitting neurological protein aggregation kinetic d [...] curated model icon download icon

DOID:1289

Model name Publication Status  
Proctor2007 - Age related decline of proteolysis, ubiquitin-proteome system (BIOMD0000000105) An in silico model of the ubiquitin-proteasome sys [...] curated model icon download icon
Proctor2010 - UCHL1 Protein Aggregation (BIOMD0000000293) Modelling the role of UCH-L1 on protein aggregatio [...] curated model icon download icon
Proctor2011_ProteinHomeostasis_NormalCondition (BIOMD0000000344) Modelling the role of the Hsp70/Hsp90 system in th [...] curated model icon download icon
Tang2010_PolyGlutamate (BIOMD0000000285) Experimental and computational analysis of polyglu [...] curated model icon download icon

DOID:14330

Model name Publication Status  
Auer2010 - Correlation between lag time and aggregation rate in protein aggregation (BIOMD0000000555) Insight into the correlation between lag time and [...] curated model icon download icon
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon
Cloutier2012 - Feedback motif for Parkinson's disease (BIOMD0000000558) Feedback motif for the pathogenesis of Parkinson's [...] curated model icon download icon
Grange2001 - L Dopa PK model (BIOMD0000000321) A pharmacokinetic model to predict the PK interact [...] curated model icon download icon
Grange2001 - PK interaction of L-dopa and benserazide (BIOMD0000000320) A pharmacokinetic model to predict the PK interact [...] curated model icon download icon
Kuznetsov2016(II) - α-syn aggregation kinetics in Parkinson's Disease (BIOMD0000000615) What can trigger the onset of Parkinson's disease [...] curated model icon download icon
Martins2013 - True and apparent inhibition of amyloid fribril formation (BIOMD0000000561) True and apparent inhibition of amyloid fibril for [...] curated model icon download icon
Morris2008 - Fitting protein aggregation data via F-W 2-step mechanism (BIOMD0000000567) Fitting neurological protein aggregation kinetic d [...] curated model icon download icon
Morris2009 - α-Synuclein aggregation variable temperature and pH (BIOMD0000000566) Alpha-synuclein aggregation variable temperature a [...] curated model icon download icon
Ouzounoglou2014 - Modeling of alpha-synuclein effects on neuronal homeostasis (BIOMD0000000559) In silico modeling of the effects of alpha-synucle [...] curated model icon download icon
Proctor2005 - Actions of chaperones and their role in ageing (BIOMD0000000091) Modelling the actions of chaperones and their role [...] curated model icon download icon
Proctor2010 - UCHL1 Protein Aggregation (BIOMD0000000293) Modelling the role of UCH-L1 on protein aggregatio [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon
Sass2009 - Approach to an α-synuclein-based BST model of Parkinson's disease (BIOMD0000000575) A pragmatic approach to biochemical systems theory [...] curated model icon download icon
Sneppen2009 - Modeling proteasome dynamics in Parkinson's disease (BIOMD0000000548) Modeling proteasome dynamics in Parkinson's diseas [...] curated model icon download icon

DOID:1612

Model name Publication Status  
Morrison1989 - Folate Cycle (BIOMD0000000018) Folate cycle kinetics in human breast cancer cells [...] curated model icon download icon
Mufudza2012 - Estrogen effect on the dynamics of breast cancer (MODEL1304190001) Assessing the effects of estrogen on the dynamics [...] non-curated model icon download icon

DOID:162

Model name Publication Status  
Barr2016 - All-or-nothing G1/S transition (BIOMD0000000646) A Dynamical Framework for the All-or-None G1/S Tra [...] curated model icon download icon
Capuani2015 - Binding of Cbl and Gbr2 to EGFR (Multisite Phosphorylation Model - MPM) (BIOMD0000000594) Quantitative analysis reveals how EGFR activation [...] curated model icon download icon
Capuani2015 - Binding of Cbl and Grb2 to EGFR (Early Activation Model - EAM) (BIOMD0000000595) Quantitative analysis reveals how EGFR activation [...] curated model icon download icon
Faratian2009 - Role of PTEN in Trastuzumab resistance (BIOMD0000000424) Systems biology reveals new strategies for persona [...] curated model icon download icon
Mosca2012 - Central Carbon Metabolism Regulated by AKT (BIOMD0000000426) Computational modeling of the metabolic States reg [...] curated model icon download icon
Orton2009 - Modelling cancerous mutations in the EGFR/ERK pathway - EGF Model (BIOMD0000000623) Computational modelling of cancerous mutations in [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon

DOID:332

Model name Publication Status  
Wang2008 - Mimicking the inhibitory effect of riluzole on membrane conductance in skeletal fibres (BIOMD0000000693) Riluzole-induced block of voltage-gated Na+ curren [...] curated model icon download icon
Wang2008_Rilusole_SkeletalMuscleCells (MODEL7817907010) Riluzole-induced block of voltage-gated Na+ curren [...] non-curated model icon download icon

DOID:3393

Model name Publication Status  
Muller2008_ThrombinGeneration_minimal (BIOMD0000000367) Tolerance and threshold in the extrinsic coagulati [...] curated model icon download icon

Down syndrome

Model name Publication Status  
Kowald2006_SOD (BIOMD0000000108) Alternative pathways as mechanism for the negative [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon

Helicobacter pylori infectious disease

Model name Publication Status  
Philipson2015 - Innate immune response modulated by NLRX1 (BIOMD0000000596) Modeling the Regulatory Mechanisms by Which NLRX1 [...] curated model icon download icon

Hodgkin's lymphoma

Model name Publication Status  
Raia2011 - IL13 L1236 (BIOMD0000000314) Dynamic mathematical modeling of IL13-induced sign [...] curated model icon download icon

Paget's disease of bone

Model name Publication Status  
Komarova2003_BoneRemodeling (BIOMD0000000148) Mathematical model predicts a critical role for os [...] curated model icon download icon

acute pancreatitis

Model name Publication Status  
Wollbold2014 - Effects of reactive oxygen species (MODEL1407230001) Anti-inflammatory effects of reactive oxygen speci [...] non-curated model icon download icon

amyloidosis

Model name Publication Status  
Ferreira2003_CML_generation2 (BIOMD0000000053) A quantitative model of the generation of N(epsilo [...] curated model icon download icon

asthma

Model name Publication Status  
Demin2013 - PKPD behaviour - 5-Lipoxygenase inhibitors (BIOMD0000000490) Systems pharmacology models can be used to underst [...] curated model icon download icon

autistic disorder

Model name Publication Status  
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon

bacterial infectious disease

Model name Publication Status  
Carbo2013 - Cytokine driven CD4+ T Cell differentiation and phenotype plasticity (BIOMD0000000451) Systems modeling of molecular mechanisms controlli [...] curated model icon download icon
Carbo2013 - Mucosal Immune Response during H.pylori Infection (BIOMD0000000480) Predictive computational modeling of the mucosal i [...] curated model icon download icon
Chan2004_TCell_receptor_activation (BIOMD0000000120) Feedback control of T-cell receptor activation. curated model icon download icon
Liu2011_Complement_System (BIOMD0000000303) A computational and experimental study of the regu [...] curated model icon download icon
Tan2012 - Antibiotic Treatment, Inoculum Effect (BIOMD0000000425) The inoculum effect and band-pass bacterial respon [...] curated model icon download icon

benign glioma

Model name Publication Status  
Ribba2012 - Low-grade gliomas, tumour growth inhibition model (BIOMD0000000521) A tumor growth inhibition model for low-grade glio [...] curated model icon download icon

blood coagulation disease

Model name Publication Status  
Nayak2015 - Blood Coagulation Network - Predicting the Effects of Various Therapies on Biomarkers (BIOMD0000000611) Using a Systems Pharmacology Model of the Blood Co [...] curated model icon download icon

botulism

Model name Publication Status  
Lebeda2008 - BoNT paralysis (3 step model) (BIOMD0000000267) Onset dynamics of type A botulinum neurotoxin-indu [...] curated model icon download icon
Lebeda2008 - BoTN Paralysis (4 step model) (BIOMD0000000178) Onset dynamics of type A botulinum neurotoxin-indu [...] curated model icon download icon

calcium metabolism disease

Model name Publication Status  
Shrestha2010_HyperCalcemia_PTHresponse (BIOMD0000000277) A mathematical model of parathyroid hormone respon [...] curated model icon download icon
Shrestha2010_HypoCalcemia_PTHresponse (BIOMD0000000276) A mathematical model of parathyroid hormone respon [...] curated model icon download icon

cardiovascular system disease

Model name Publication Status  
Orfao2008_ThrombinGeneration_AmidolyticActivity (BIOMD0000000366) Qualitative properties and stabilizability of a mo [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon

cartilage disease

Model name Publication Status  
Proctor2013 - Cartilage breakdown, interventions to reduce collagen release (BIOMD0000000504) A computer simulation approach for assessing thera [...] curated model icon download icon

cataract

Model name Publication Status  
Proctor2005 - Actions of chaperones and their role in ageing (BIOMD0000000091) Modelling the actions of chaperones and their role [...] curated model icon download icon

cerebral degeneration

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

cholesterol embolism

Model name Publication Status  
Bucher2011_Atorvastatin_Metabolism (BIOMD0000000328) A systems biology approach to dynamic modeling and [...] curated model icon download icon

cholesterol ester storage disease

Model name Publication Status  
McAuley2012 - Whole-body Cholesterol Metabolism (BIOMD0000000434) A whole-body mathematical model of cholesterol met [...] curated model icon download icon

colorectal cancer

Model name Publication Status  
Kim2007 - Crosstalk between Wnt and ERK pathways (BIOMD0000000149) A hidden oncogenic positive feedback loop caused b [...] curated model icon download icon

diabetes mellitus

Model name Publication Status  
Alvehag2006_IVGTT_GlucoseModel_A (MODEL1112110000) The Feedback Control of Glucose: On the road to ty [...] non-curated model icon download icon
Alvehag2006_OGTT_GlucoseModel_B (MODEL1112110001) The Feedback Control of Glucose: On the road to ty [...] non-curated model icon download icon
Bertram2004_PancreaticBetaCell_modelB (BIOMD0000000373) Calcium and glycolysis mediate multiple bursting m [...] curated model icon download icon
Brannmark2010_InsulinSignalling_Mifamodel (BIOMD0000000343) Mass and information feedbacks through receptor en [...] curated model icon download icon
DallaMan2007_MealModel_GlucoseInsulinSystem (BIOMD0000000379) Meal simulation model of the glucose-insulin syste [...] curated model icon download icon
DeVries2000_PancreaticBetaCells_InsulinSecretion (BIOMD0000000371) Channel sharing in pancreatic beta -cells revisite [...] curated model icon download icon
Ferreira2003_CML_generation2 (BIOMD0000000053) A quantitative model of the generation of N(epsilo [...] curated model icon download icon
Fridlyand2010_GlucoseSensitivity_A (BIOMD0000000348) Glucose sensing in the pancreatic beta cell: a com [...] curated model icon download icon
Fridlyand2010_GlucoseSensitivity_B (BIOMD0000000349) Glucose sensing in the pancreatic beta cell: a com [...] curated model icon download icon
Jiang2007 - GSIS system, Pancreatic Beta Cells (BIOMD0000000239) A kinetic core model of the glucose-stimulated ins [...] curated model icon download icon
Koenig2012 Hepatic Glucose Metabolism (MODEL1204270001) Quantifying the contribution of the liver to gluco [...] non-curated model icon download icon
Koenig2012 Hepatic Glucose Metabolism in Type 2 Diabetes (MODEL1209260000) Kinetic modeling of human hepatic glucose metaboli [...] non-curated model icon download icon
Koschorreck2008_InsulinClearance (BIOMD0000000345) Mathematical modeling and analysis of insulin clea [...] curated model icon download icon
Lenbury2001_InsulinKineticsModel_A (MODEL1201140002) Modeling insulin kinetics: responses to a single o [...] non-curated model icon download icon
Lenbury2001_InsulinKineticsModel_B (MODEL1201140003) Modeling insulin kinetics: responses to a single o [...] non-curated model icon download icon
Noguchi2013 - Insulin dependent glucose metabolism (BIOMD0000000482) The selective control of glycolysis, gluconeogenes [...] curated model icon download icon
Nyman2011_M3Hierarachical_InsulinGlucosedynamics (BIOMD0000000356) A hierarchical whole-body modeling approach elucid [...] curated model icon download icon
Sedaghat2002_InsulinSignalling_noFeedback (BIOMD0000000137) A mathematical model of metabolic insulin signalin [...] curated model icon download icon
Smith2013 - Regulation of Insulin Signalling by Oxidative Stress (BIOMD0000000474) Computational modelling of the regulation of Insul [...] curated model icon download icon
Sturis1991_InsulinGlucoseModel_UltradianOscillation (BIOMD0000000382) Computer model for mechanisms underlying ultradian [...] curated model icon download icon
Tolic2000_InsulinGlucoseFeedback (BIOMD0000000372) Modeling the insulin-glucose feedback system: the [...] curated model icon download icon
Topp2000_BetaCellMass_Diabetes (BIOMD0000000341) A model of beta-cell mass, insulin, and glucose ki [...] curated model icon download icon

disease by infectious agent

Model name Publication Status  
Munz2009 - Zombi Impulsive Killing (MODEL1008060000) When Zombies Attack!: Mathematical modelling of an [...] non-curated model icon download icon
Munz2009 - Zombie SIZRC (MODEL1008060001) When Zombies Attack!: Mathematical modelling of an [...] non-curated model icon download icon
Munz2009 - Zombie SIZRQ (MODEL1008060002) When Zombies Attack!: Mathematical modelling of an [...] non-curated model icon download icon
Munz2009 - Zombie basic SZR (MODEL1009230000) When Zombies Attack!: Mathematical modelling of an [...] non-curated model icon download icon

duodenal ulcer

Model name Publication Status  
Leber2016 - Expanded model of Tfh-Tfr differentiation - Helicobacter pylori infection (BIOMD0000000625) Bistability analyses of CD4+ T follicular helper a [...] curated model icon download icon

fatty liver disease

Model name Publication Status  
Tiemann2011_PhenotypeTransitions (MODEL1112150000) Parameter adaptations during phenotype transitions [...] non-curated model icon download icon

glucocorticoid-remediable aldosteronism

Model name Publication Status  
Komarova2005_PTHaction_OsteoclastOsteoblastCoupling (BIOMD0000000279) Mathematical model of paracrine interactions betwe [...] curated model icon download icon
Lemaire2004 - Role of RANK/RANKL/OPG pathway in bone remodelling process (BIOMD0000000278) Modeling the interactions between osteoblast and o [...] curated model icon download icon

heart disease

Model name Publication Status  
Bucher2011_Atorvastatin_Metabolism (BIOMD0000000328) A systems biology approach to dynamic modeling and [...] curated model icon download icon
Saucerman2006_PKA (BIOMD0000000165) Systems analysis of PKA-mediated phosphorylation g [...] curated model icon download icon
Wang2008_Neonatal_heartfunction (MODEL7814665196) Mathematical model of the neonatal mouse ventricul [...] non-curated model icon download icon

hemochromatosis

Model name Publication Status  
Mitchell2013 - Liver Iron Metabolism (BIOMD0000000498) A computational model of liver iron metabolism. curated model icon download icon

hemophilia B

Model name Publication Status  
Wajima2009_BloodCoagulation_PTtest (BIOMD0000000339) A comprehensive model for the humoral coagulation [...] curated model icon download icon
Wajima2009_BloodCoagulation_aPTTtest (BIOMD0000000338) A comprehensive model for the humoral coagulation [...] curated model icon download icon
Wajima2009_BloodCoagulation_warfarin_heparin (BIOMD0000000340) A comprehensive model for the humoral coagulation [...] curated model icon download icon

human immunodeficiency virus infectious disease

Model name Publication Status  
Aguilera 2014 - HIV latency. Interaction between HIV proteins and immune response (BIOMD0000000573) Studying HIV latency by modeling the interaction b [...] curated model icon download icon
Nelson2000_HIV-1_general_model (MODEL8268650277) A model of HIV-1 pathogenesis that includes an int [...] non-curated model icon download icon
Nelson2000_HIV-1_intracellular_delay (MODEL8102792069) A model of HIV-1 pathogenesis that includes an int [...] non-curated model icon download icon

hyperparathyroidism

Model name Publication Status  
Peterson2010 - Integrated calcium homeostasis and bone remodelling (BIOMD0000000613) A physiologically based mathematical model of inte [...] curated model icon download icon

hypersensitivity reaction type II disease

Model name Publication Status  
Alexander2010_Tcell_Regulation_Sys1 (BIOMD0000000289) Self-tolerance and autoimmunity in a regulatory T [...] curated model icon download icon
Alexander2010_Tcell_Regulation_Sys2 (BIOMD0000000290) Self-tolerance and autoimmunity in a regulatory T [...] curated model icon download icon

hypoparathyroidism

Model name Publication Status  
Peterson2010 - Integrated calcium homeostasis and bone remodelling (BIOMD0000000613) A physiologically based mathematical model of inte [...] curated model icon download icon

immune system disease

Model name Publication Status  
Dunster2014 - WBC Interactions (Model1) (BIOMD0000000616) The resolution of inflammation: a mathematical mod [...] curated model icon download icon

influenza

Model name Publication Status  
Fribourg2014 - Dynamics of viral antagonism and innate immune response (H1N1 influenza A virus - NC/99) (BIOMD0000000529) Model of influenza A virus infection: dynamics of [...] curated model icon download icon
Heldt2012 - Influenza Virus Replication (BIOMD0000000463) Modeling the intracellular dynamics of influenza v [...] curated model icon download icon
Miao2010 - Innate and adaptive immune responses to primary Influenza A Virus infection (BIOMD0000000546) Quantifying the early immune response and adaptive [...] curated model icon download icon

inherited blood coagulation disease

Model name Publication Status  
Hockin1999_BloodCoagulation_VaInactivation (BIOMD0000000365) A model describing the inactivation of factor Va b [...] curated model icon download icon

leishmaniasis

Model name Publication Status  
Mandlik2013 - Synthetic circuit of IPC synthase in Leishmania (MODEL1208030000) Synthetic circuit of inositol phosphorylceramide s [...] non-curated model icon download icon
Mandlik2015 - Tristable genetic circuit of Leishmania (BIOMD0000000584) Regulatory dynamics of network architecture and fu [...] curated model icon download icon
Mol2013 - Immune Signal Transduction in Leishmaniasis (BIOMD0000000477) Immune signal transduction in leishmaniasis from n [...] curated model icon download icon
Mol2013 - Leishmania macrophage signaling network (MODEL1203220000) Signaling networks in Leishmania macrophages decip [...] non-curated model icon download icon

liver disease

Model name Publication Status  
Mueller2015 - Hepatocyte proliferation, T160 phosphorylation of CDK2 (BIOMD0000000568) T160?phosphorylated CDK2 defines threshold for HGF [...] curated model icon download icon
Nikolaev2005_AlbuminBilirubinAdsorption (BIOMD0000000291) Mathematical model of binding of albumin-bilirubin [...] curated model icon download icon

lung cancer

Model name Publication Status  
Tham2008 - PDmodel, Tumour shrinkage by gemcitabine and carboplatin (BIOMD0000000234) A pharmacodynamic model for the time course of tum [...] curated model icon download icon

mature T-cell and NK-cell lymphoma

Model name Publication Status  
Raia2010 - IL13 Signalling MedB1 (BIOMD0000000313) Dynamic mathematical modeling of IL13-induced sign [...] curated model icon download icon

multiple myeloma

Model name Publication Status  
Ayati2010_BoneRemodelingDynamics_NormalCondition (BIOMD0000000401) A mathematical model of bone remodeling dynamics f [...] curated model icon download icon
Ayati2010_BoneRemodelingDynamics_WithTumour (BIOMD0000000402) A mathematical model of bone remodeling dynamics f [...] curated model icon download icon
Ayati2010_BoneRemodelingDynamics_WithTumour+DrugTreatment (BIOMD0000000403) A mathematical model of bone remodeling dynamics f [...] curated model icon download icon

neonatal abstinence syndrome

Model name Publication Status  
Yang2006_Methadone_PKmodel (MODEL1006230040) Population-based analysis of methadone distributio [...] non-curated model icon download icon

non-small cell lung carcinoma

Model name Publication Status  
Bianconi2012 - EGFR and IGF1R pathway in lung cancer (BIOMD0000000427) Computational model of EGFR and IGF1R pathways in [...] curated model icon download icon
Bidkhori2012 - EGFR signalling in NSCLC (BIOMD0000000453) Modeling of tumor progression in NSCLC and intrins [...] curated model icon download icon

ocular albinism

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

osteoarthritis

Model name Publication Status  
Benson2014 - FAAH inhibitors for the treatment of osteoarthritic pain (BIOMD0000000512) A systems pharmacology perspective on the clinical [...] curated model icon download icon
Hui2014 - Age-related changes in articular cartilage (BIOMD0000000560) Oxidative changes and signalling pathways are pivo [...] curated model icon download icon
Komarova2003_BoneRemodeling (BIOMD0000000148) Mathematical model predicts a critical role for os [...] curated model icon download icon

osteoporosis

Model name Publication Status  
Komarova2003_BoneRemodeling (BIOMD0000000148) Mathematical model predicts a critical role for os [...] curated model icon download icon

ovarian disease

Model name Publication Status  
Roblitz2013 - Menstrual Cycle following GnRH analogue administration (BIOMD0000000494) A mathematical model of the human menstrual cycle [...] curated model icon download icon
Stötzel2012 - Bovine estrous cycle, synchronization with prostaglandin F2α (BIOMD0000000481) Advances in modeling of the bovine estrous cycle: [...] curated model icon download icon

pancreatic cancer

Model name Publication Status  
Rateitschak2012 - Interferon-gamma (IFNγ) induced STAT1 signalling (PC_IFNg100) (BIOMD0000000585) Parameter identifiability and sensitivity analysis [...] curated model icon download icon

peptic ulcer disease

Model name Publication Status  
Leber2016 - Expanded model of Tfh-Tfr differentiation - Helicobacter pylori infection (BIOMD0000000625) Bistability analyses of CD4+ T follicular helper a [...] curated model icon download icon

pertussis

Model name Publication Status  
Restif2006 - Whooping cough (BIOMD0000000249) Integrating life history and cross-immunity into t [...] curated model icon download icon
Restif2007 - Vaccination invasion (BIOMD0000000294) Vaccination and the dynamics of immune evasion. curated model icon download icon

polycythemia due to hypoxia

Model name Publication Status  
Hunziker2010_p53_StressSpecificResponse (BIOMD0000000252) Stress-specific response of the p53-Mdm2 feedback [...] curated model icon download icon
Schmierer2010_FIH_Ankyrins (BIOMD0000000300) Hypoxia-dependent sequestration of an oxygen senso [...] curated model icon download icon

primary bacterial infectious disease

Model name Publication Status  
Kaiser2014 - Salmonella persistence after ciprofloxacin treatment (BIOMD0000000527) Cecum lymph node dendritic cells harbor slow-growi [...] curated model icon download icon

prion disease

Model name Publication Status  
Martins2013 - True and apparent inhibition of amyloid fribril formation (BIOMD0000000561) True and apparent inhibition of amyloid fibril for [...] curated model icon download icon

retinal degeneration

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

retinal detachment

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

retinal disease

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

rheumatoid arthritis

Model name Publication Status  
Baker2013 - Cytokine Mediated Inflammation in Rheumatoid Arthritis (BIOMD0000000550) Mathematical modelling of cytokine-mediated inflam [...] curated model icon download icon
Baker2013 - Cytokine Mediated Inflammation in Rheumatoid Arthritis - Age Dependent (BIOMD0000000549) Mathematical modelling of cytokine-mediated inflam [...] curated model icon download icon

swine influenza

Model name Publication Status  
Fribourg2014 - Dynamics of viral antagonism and innate immune response (H1N1 influenza A virus - Cal/09) (BIOMD0000000528) Model of influenza A virus infection: dynamics of [...] curated model icon download icon

tauopathy

Model name Publication Status  
Yuraszeck2010 - Vulnerabilities in the Tau Network in Tau Pathophysiology (BIOMD0000000542) Vulnerabilities in the tau network and the role of [...] curated model icon download icon

tuberculosis

Model name Publication Status  
Palsson2013 - Fully-integrated immune response model (FIRM) (BIOMD0000000608) The development of a fully-integrated immune respo [...] curated model icon download icon

type 1 diabetes mellitus

Model name Publication Status  
Maree2006_DuCa_Type1DiabetesModel (BIOMD0000000381) Modelling the onset of Type 1 diabetes: can impair [...] curated model icon download icon

type 2 diabetes mellitus

Model name Publication Status  
Brännmark2013 - Insulin signalling in human adipocytes (diabetic condition) (BIOMD0000000449) Insulin signaling in type 2 diabetes: experimental [...] curated model icon download icon
Brännmark2013 - Insulin signalling in human adipocytes (normal condition) (BIOMD0000000448) Insulin signaling in type 2 diabetes: experimental [...] curated model icon download icon
Palmer2014 - Effect of IL-1β-Blocking therapies in T2DM - Disease Condition (BIOMD0000000620) Effects of IL-1β-Blocking Therapies in Type 2 Diab [...] curated model icon download icon
Palmer2014 - Effect of IL-1β-Blocking therapies in T2DM - Healthy Condition (BIOMD0000000621) Effects of IL-1β-Blocking Therapies in Type 2 Diab [...] curated model icon download icon
Silber2007_IntravenousGlucose_IntegratedGlucoseInsulinModel (MODEL1112110004) An integrated model for glucose and insulin regula [...] non-curated model icon download icon

See also: Human Disease Ontology.

Online Mendelian Inheritance in Man

BH3-INTERACTING DOMAIN DEATH AGONIST; BID

Model name Publication Status  
Albeck2008_extrinsic_apoptosis (BIOMD0000000220) Quantitative analysis of pathways controlling extr [...] curated model icon download icon

BRUGADA SYNDROME 1; BRGDA1

Model name Publication Status  
Clancy2002_CardiacSodiumChannel_WT (BIOMD0000000126) Na(+) channel mutation that causes both Brugada an [...] curated model icon download icon

CASP8- AND FADD-LIKE APOPTOSIS REGULATOR; CFLAR

Model name Publication Status  
Albeck2008_extrinsic_apoptosis (BIOMD0000000220) Quantitative analysis of pathways controlling extr [...] curated model icon download icon

DUAL-SPECIFICITY PHOSPHATASE 1; DUSP1

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon

DUAL-SPECIFICITY PHOSPHATASE 4; DUSP4

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon

DUAL-SPECIFICITY PHOSPHATASE 6; DUSP6

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon

EPIDERMAL GROWTH FACTOR; EGF

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon

GRB2-ASSOCIATED BINDING PROTEIN 1; GAB1

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon

GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2; GRB2

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon
Chen2009 - ErbB Signaling (BIOMD0000000255) Input-output behavior of ErbB signaling pathways a [...] curated model icon download icon
Jenkinson2011_EGF_MAPK (BIOMD0000000399) Thermodynamically consistent model calibration in [...] curated model icon download icon
Schoeberl2002 - EGF MAPK (BIOMD0000000019) Computational modeling of the dynamics of the MAP [...] curated model icon download icon

HAIRY/ENHANCER OF SPLIT, DROSOPHILA, HOMOLOG OF, 1; HES1

Model name Publication Status  
Sivakumar2011_NeuralStemCellDifferentiation_Crosstalk (BIOMD0000000398) A systems biology approach to model neural stem ce [...] curated model icon download icon

INTERLEUKIN 21; IL21

Model name Publication Status  
Overgaard2007_PDmodel_IL21 (BIOMD0000000238) PKPD model of interleukin-21 effects on thermoregu [...] curated model icon download icon

LONG QT SYNDROME 3; LQT3

Model name Publication Status  
Clancy2002_CardiacSodiumChannel_WT (BIOMD0000000126) Na(+) channel mutation that causes both Brugada an [...] curated model icon download icon

MITOGEN-ACTIVATED PROTEIN KINASE 1; MAPK1

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon
Chen2009 - ErbB Signaling (BIOMD0000000255) Input-output behavior of ErbB signaling pathways a [...] curated model icon download icon
Jenkinson2011_EGF_MAPK (BIOMD0000000399) Thermodynamically consistent model calibration in [...] curated model icon download icon
Schoeberl2002 - EGF MAPK (BIOMD0000000019) Computational modeling of the dynamics of the MAP [...] curated model icon download icon

MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1; MAP2K1

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon
Chen2009 - ErbB Signaling (BIOMD0000000255) Input-output behavior of ErbB signaling pathways a [...] curated model icon download icon
Jenkinson2011_EGF_MAPK (BIOMD0000000399) Thermodynamically consistent model calibration in [...] curated model icon download icon
Schoeberl2002 - EGF MAPK (BIOMD0000000019) Computational modeling of the dynamics of the MAP [...] curated model icon download icon

NEUREGULIN 1; NRG1

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon

NITRIC OXIDE SYNTHASE 1; NOS1

Model name Publication Status  
Santolini2001_nNOS_Mechanism_Regulation (BIOMD0000000199) A kinetic simulation model that describes catalysi [...] curated model icon download icon

POTASSIUM CHANNEL, VOLTAGE-GATED, SUBFAMILY H, MEMBER 2; KCNH2

Model name Publication Status  
Clancy2001_Kchannel (BIOMD0000000121) Cellular consequences of HERG mutations in the lon [...] curated model icon download icon

PROTEIN-TYROSINE PHOSPHATASE, NONRECEPTOR-TYPE, 1; PTPN1

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon

RAS p21 PROTEIN ACTIVATOR 1; RASA1

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon
Chen2009 - ErbB Signaling (BIOMD0000000255) Input-output behavior of ErbB signaling pathways a [...] curated model icon download icon
Jenkinson2011_EGF_MAPK (BIOMD0000000399) Thermodynamically consistent model calibration in [...] curated model icon download icon
Schoeberl2002 - EGF MAPK (BIOMD0000000019) Computational modeling of the dynamics of the MAP [...] curated model icon download icon

SHC TRANSFORMING PROTEIN 2; SHC2

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon
Chen2009 - ErbB Signaling (BIOMD0000000255) Input-output behavior of ErbB signaling pathways a [...] curated model icon download icon
Jenkinson2011_EGF_MAPK (BIOMD0000000399) Thermodynamically consistent model calibration in [...] curated model icon download icon
Schoeberl2002 - EGF MAPK (BIOMD0000000019) Computational modeling of the dynamics of the MAP [...] curated model icon download icon

SON OF SEVENLESS, DROSOPHILA, HOMOLOG 1; SOS1

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon
Chen2009 - ErbB Signaling (BIOMD0000000255) Input-output behavior of ErbB signaling pathways a [...] curated model icon download icon
Jenkinson2011_EGF_MAPK (BIOMD0000000399) Thermodynamically consistent model calibration in [...] curated model icon download icon
Schoeberl2002 - EGF MAPK (BIOMD0000000019) Computational modeling of the dynamics of the MAP [...] curated model icon download icon

V-AKT MURINE THYMOMA VIRAL ONCOGENE HOMOLOG 3; AKT3

Model name Publication Status  
Birtwistle2007_ErbB_Signalling (BIOMD0000000175) Ligand-dependent responses of the ErbB signaling n [...] curated model icon download icon

V-RAF-1 MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1; RAF1

Model name Publication Status  
Chen2009 - ErbB Signaling (BIOMD0000000255) Input-output behavior of ErbB signaling pathways a [...] curated model icon download icon
Schoeberl2002 - EGF MAPK (BIOMD0000000019) Computational modeling of the dynamics of the MAP [...] curated model icon download icon

See also: Online Mendelian Inheritance in Man

International Classification of Diseases

Andersen-Tawil syndrome

Model name Publication Status  
Clancy2001_Kchannel (BIOMD0000000121) Cellular consequences of HERG mutations in the lon [...] curated model icon download icon

Brugada syndrome

Model name Publication Status  
Clancy2002_CardiacSodiumChannel_WT (BIOMD0000000126) Na(+) channel mutation that causes both Brugada an [...] curated model icon download icon

Clostridium difficile colitis

Model name Publication Status  
Leber2015 - Mucosal immunity and gut microbiome interaction during C. difficile infection (BIOMD0000000583) Systems Modeling of Interactions between Mucosal I [...] curated model icon download icon

Crohn's disease

Model name Publication Status  
Dwivedi2014 - Crohns IL6 Disease model - Anti-IL6 Antibody (BIOMD0000000535) A multiscale model of interleukin-6-mediated immun [...] curated model icon download icon
Dwivedi2014 - Crohns IL6 Disease model - Anti-IL6R Antibody (BIOMD0000000537) A multiscale model of interleukin-6-mediated immun [...] curated model icon download icon
Dwivedi2014 - Crohns IL6 Disease model - sgp130 activity (BIOMD0000000536) A multiscale model of interleukin-6-mediated immun [...] curated model icon download icon
Dwivedi2014 - Healthy Volunteer IL6 Model (BIOMD0000000534) A multiscale model of interleukin-6-mediated immun [...] curated model icon download icon

DOID: 0060075

Model name Publication Status  
Mufudza2012 - Estrogen effect on the dynamics of breast cancer (BIOMD0000000642) Assessing the effects of estrogen on the dynamics [...] curated model icon download icon

DOID:10652

Model name Publication Status  
Auer2010 - Correlation between lag time and aggregation rate in protein aggregation (BIOMD0000000555) Insight into the correlation between lag time and [...] curated model icon download icon
Crespo2012 - Kinetics of Amyloid Fibril Formation (BIOMD0000000531) A generic crystallization-like model that describe [...] curated model icon download icon
Das2010 - Effect of a gamma-secretase inhibitor on Amyloid-beta dynamics (BIOMD0000000551) Modeling effect of a γ-secretase inhibitor on amyl [...] curated model icon download icon
Ehrenstein1997 - The choline-leakage hypothesis in Alzheimer's disease (BIOMD0000000553) The choline-leakage hypothesis for the loss of ace [...] curated model icon download icon
Ehrenstein2000 - Positive-Feedback model for the loss of acetylcholine in Alzheimer's disease (BIOMD0000000552) A positive-feedback model for the loss of acetylch [...] curated model icon download icon
Krohn2011 - Cerebral amyloid-β proteostasis regulated by membrane transport protein ABCC1 (BIOMD0000000618) Cerebral amyloid-? proteostasis is regulated by th [...] curated model icon download icon
Lockwood2006_PKPD_AlzheimersDisease (MODEL1006230054) Application of clinical trial simulation to compar [...] non-curated model icon download icon
Martins2013 - True and apparent inhibition of amyloid fribril formation (BIOMD0000000561) True and apparent inhibition of amyloid fibril for [...] curated model icon download icon
Morris2008 - Fitting protein aggregation data via F-W 2-step mechanism (BIOMD0000000567) Fitting neurological protein aggregation kinetic d [...] curated model icon download icon
Ortega2013 - Interplay between secretases determines biphasic amyloid-beta level (BIOMD0000000556) Interplay between α-, β-, and γ-secretases determi [...] curated model icon download icon
Proctor2005 - Actions of chaperones and their role in ageing (BIOMD0000000091) Modelling the actions of chaperones and their role [...] curated model icon download icon
Proctor2010 - a link between GSK3 and p53 in Alzheimer's Disease (BIOMD0000000286) GSK3 and p53 - is there a link in Alzheimer's dise [...] curated model icon download icon
Proctor2012 - Role of Amyloid-beta dimers in aggregation formation (BIOMD0000000462) Aggregation, impaired degradation and immunization [...] curated model icon download icon
Proctor2013 - Effect of Aβ immunisation in Alzheimer's disease (deterministic version) (BIOMD0000000488) Investigating interventions in Alzheimer's disease [...] curated model icon download icon
Proctor2013 - Effect of Aβ immunisation in Alzheimer's disease (stochastic version) (BIOMD0000000634) Investigating interventions in Alzheimer's disease [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon
Steckmann2012 - Amyloid beta-protein fibrillogenesis (kinetics of secondary structure conversion) (BIOMD0000000533) Kinetics of peptide secondary structure conversion [...] curated model icon download icon
Vazquez2014 - Chemical inhibition from amyloid protein aggregation kinetics (BIOMD0000000532) Modeling of chemical inhibition from amyloid prote [...] curated model icon download icon
Walsh2014 - Inhibition kinetics of DAPT on APP Cleavage (BIOMD0000000617) Are improper kinetic models hampering drug develop [...] curated model icon download icon
Winter2017 - Brain Energy Metabolism with PPP (BIOMD0000000627) Mathematical analysis of the influence of brain me [...] curated model icon download icon
Yuraszeck2010 - Vulnerabilities in the Tau Network in Tau Pathophysiology (BIOMD0000000542) Vulnerabilities in the tau network and the role of [...] curated model icon download icon

DOID:12858

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon
Morris2008 - Fitting protein aggregation data via F-W 2-step mechanism (BIOMD0000000567) Fitting neurological protein aggregation kinetic d [...] curated model icon download icon

DOID:1289

Model name Publication Status  
Proctor2007 - Age related decline of proteolysis, ubiquitin-proteome system (BIOMD0000000105) An in silico model of the ubiquitin-proteasome sys [...] curated model icon download icon
Proctor2010 - UCHL1 Protein Aggregation (BIOMD0000000293) Modelling the role of UCH-L1 on protein aggregatio [...] curated model icon download icon
Proctor2011_ProteinHomeostasis_NormalCondition (BIOMD0000000344) Modelling the role of the Hsp70/Hsp90 system in th [...] curated model icon download icon
Tang2010_PolyGlutamate (BIOMD0000000285) Experimental and computational analysis of polyglu [...] curated model icon download icon

DOID:14330

Model name Publication Status  
Auer2010 - Correlation between lag time and aggregation rate in protein aggregation (BIOMD0000000555) Insight into the correlation between lag time and [...] curated model icon download icon
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon
Cloutier2012 - Feedback motif for Parkinson's disease (BIOMD0000000558) Feedback motif for the pathogenesis of Parkinson's [...] curated model icon download icon
Grange2001 - L Dopa PK model (BIOMD0000000321) A pharmacokinetic model to predict the PK interact [...] curated model icon download icon
Grange2001 - PK interaction of L-dopa and benserazide (BIOMD0000000320) A pharmacokinetic model to predict the PK interact [...] curated model icon download icon
Kuznetsov2016(II) - α-syn aggregation kinetics in Parkinson's Disease (BIOMD0000000615) What can trigger the onset of Parkinson's disease [...] curated model icon download icon
Martins2013 - True and apparent inhibition of amyloid fribril formation (BIOMD0000000561) True and apparent inhibition of amyloid fibril for [...] curated model icon download icon
Morris2008 - Fitting protein aggregation data via F-W 2-step mechanism (BIOMD0000000567) Fitting neurological protein aggregation kinetic d [...] curated model icon download icon
Morris2009 - α-Synuclein aggregation variable temperature and pH (BIOMD0000000566) Alpha-synuclein aggregation variable temperature a [...] curated model icon download icon
Ouzounoglou2014 - Modeling of alpha-synuclein effects on neuronal homeostasis (BIOMD0000000559) In silico modeling of the effects of alpha-synucle [...] curated model icon download icon
Proctor2005 - Actions of chaperones and their role in ageing (BIOMD0000000091) Modelling the actions of chaperones and their role [...] curated model icon download icon
Proctor2010 - UCHL1 Protein Aggregation (BIOMD0000000293) Modelling the role of UCH-L1 on protein aggregatio [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon
Sass2009 - Approach to an α-synuclein-based BST model of Parkinson's disease (BIOMD0000000575) A pragmatic approach to biochemical systems theory [...] curated model icon download icon
Sneppen2009 - Modeling proteasome dynamics in Parkinson's disease (BIOMD0000000548) Modeling proteasome dynamics in Parkinson's diseas [...] curated model icon download icon

DOID:1612

Model name Publication Status  
Morrison1989 - Folate Cycle (BIOMD0000000018) Folate cycle kinetics in human breast cancer cells [...] curated model icon download icon
Mufudza2012 - Estrogen effect on the dynamics of breast cancer (MODEL1304190001) Assessing the effects of estrogen on the dynamics [...] non-curated model icon download icon

DOID:162

Model name Publication Status  
Barr2016 - All-or-nothing G1/S transition (BIOMD0000000646) A Dynamical Framework for the All-or-None G1/S Tra [...] curated model icon download icon
Capuani2015 - Binding of Cbl and Gbr2 to EGFR (Multisite Phosphorylation Model - MPM) (BIOMD0000000594) Quantitative analysis reveals how EGFR activation [...] curated model icon download icon
Capuani2015 - Binding of Cbl and Grb2 to EGFR (Early Activation Model - EAM) (BIOMD0000000595) Quantitative analysis reveals how EGFR activation [...] curated model icon download icon
Faratian2009 - Role of PTEN in Trastuzumab resistance (BIOMD0000000424) Systems biology reveals new strategies for persona [...] curated model icon download icon
Mosca2012 - Central Carbon Metabolism Regulated by AKT (BIOMD0000000426) Computational modeling of the metabolic States reg [...] curated model icon download icon
Orton2009 - Modelling cancerous mutations in the EGFR/ERK pathway - EGF Model (BIOMD0000000623) Computational modelling of cancerous mutations in [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon

DOID:332

Model name Publication Status  
Wang2008 - Mimicking the inhibitory effect of riluzole on membrane conductance in skeletal fibres (BIOMD0000000693) Riluzole-induced block of voltage-gated Na+ curren [...] curated model icon download icon
Wang2008_Rilusole_SkeletalMuscleCells (MODEL7817907010) Riluzole-induced block of voltage-gated Na+ curren [...] non-curated model icon download icon

DOID:3393

Model name Publication Status  
Muller2008_ThrombinGeneration_minimal (BIOMD0000000367) Tolerance and threshold in the extrinsic coagulati [...] curated model icon download icon

Down syndrome

Model name Publication Status  
Kowald2006_SOD (BIOMD0000000108) Alternative pathways as mechanism for the negative [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon

Helicobacter pylori infectious disease

Model name Publication Status  
Philipson2015 - Innate immune response modulated by NLRX1 (BIOMD0000000596) Modeling the Regulatory Mechanisms by Which NLRX1 [...] curated model icon download icon

Hodgkin's lymphoma

Model name Publication Status  
Raia2011 - IL13 L1236 (BIOMD0000000314) Dynamic mathematical modeling of IL13-induced sign [...] curated model icon download icon

Paget's disease of bone

Model name Publication Status  
Komarova2003_BoneRemodeling (BIOMD0000000148) Mathematical model predicts a critical role for os [...] curated model icon download icon

acute pancreatitis

Model name Publication Status  
Wollbold2014 - Effects of reactive oxygen species (MODEL1407230001) Anti-inflammatory effects of reactive oxygen speci [...] non-curated model icon download icon

amyloidosis

Model name Publication Status  
Ferreira2003_CML_generation2 (BIOMD0000000053) A quantitative model of the generation of N(epsilo [...] curated model icon download icon

asthma

Model name Publication Status  
Demin2013 - PKPD behaviour - 5-Lipoxygenase inhibitors (BIOMD0000000490) Systems pharmacology models can be used to underst [...] curated model icon download icon

autistic disorder

Model name Publication Status  
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon

bacterial infectious disease

Model name Publication Status  
Carbo2013 - Cytokine driven CD4+ T Cell differentiation and phenotype plasticity (BIOMD0000000451) Systems modeling of molecular mechanisms controlli [...] curated model icon download icon
Carbo2013 - Mucosal Immune Response during H.pylori Infection (BIOMD0000000480) Predictive computational modeling of the mucosal i [...] curated model icon download icon
Chan2004_TCell_receptor_activation (BIOMD0000000120) Feedback control of T-cell receptor activation. curated model icon download icon
Liu2011_Complement_System (BIOMD0000000303) A computational and experimental study of the regu [...] curated model icon download icon
Tan2012 - Antibiotic Treatment, Inoculum Effect (BIOMD0000000425) The inoculum effect and band-pass bacterial respon [...] curated model icon download icon

benign glioma

Model name Publication Status  
Ribba2012 - Low-grade gliomas, tumour growth inhibition model (BIOMD0000000521) A tumor growth inhibition model for low-grade glio [...] curated model icon download icon

blood coagulation disease

Model name Publication Status  
Nayak2015 - Blood Coagulation Network - Predicting the Effects of Various Therapies on Biomarkers (BIOMD0000000611) Using a Systems Pharmacology Model of the Blood Co [...] curated model icon download icon

botulism

Model name Publication Status  
Lebeda2008 - BoNT paralysis (3 step model) (BIOMD0000000267) Onset dynamics of type A botulinum neurotoxin-indu [...] curated model icon download icon
Lebeda2008 - BoTN Paralysis (4 step model) (BIOMD0000000178) Onset dynamics of type A botulinum neurotoxin-indu [...] curated model icon download icon

calcium metabolism disease

Model name Publication Status  
Shrestha2010_HyperCalcemia_PTHresponse (BIOMD0000000277) A mathematical model of parathyroid hormone respon [...] curated model icon download icon
Shrestha2010_HypoCalcemia_PTHresponse (BIOMD0000000276) A mathematical model of parathyroid hormone respon [...] curated model icon download icon

cardiovascular system disease

Model name Publication Status  
Orfao2008_ThrombinGeneration_AmidolyticActivity (BIOMD0000000366) Qualitative properties and stabilizability of a mo [...] curated model icon download icon
Reed2008_Glutathione_Metabolism (BIOMD0000000268) A mathematical model of glutathione metabolism. curated model icon download icon

cartilage disease

Model name Publication Status  
Proctor2013 - Cartilage breakdown, interventions to reduce collagen release (BIOMD0000000504) A computer simulation approach for assessing thera [...] curated model icon download icon

cataract

Model name Publication Status  
Proctor2005 - Actions of chaperones and their role in ageing (BIOMD0000000091) Modelling the actions of chaperones and their role [...] curated model icon download icon

cerebral degeneration

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

cholesterol embolism

Model name Publication Status  
Bucher2011_Atorvastatin_Metabolism (BIOMD0000000328) A systems biology approach to dynamic modeling and [...] curated model icon download icon

cholesterol ester storage disease

Model name Publication Status  
McAuley2012 - Whole-body Cholesterol Metabolism (BIOMD0000000434) A whole-body mathematical model of cholesterol met [...] curated model icon download icon

colorectal cancer

Model name Publication Status  
Kim2007 - Crosstalk between Wnt and ERK pathways (BIOMD0000000149) A hidden oncogenic positive feedback loop caused b [...] curated model icon download icon

diabetes mellitus

Model name Publication Status  
Alvehag2006_IVGTT_GlucoseModel_A (MODEL1112110000) The Feedback Control of Glucose: On the road to ty [...] non-curated model icon download icon
Alvehag2006_OGTT_GlucoseModel_B (MODEL1112110001) The Feedback Control of Glucose: On the road to ty [...] non-curated model icon download icon
Bertram2004_PancreaticBetaCell_modelB (BIOMD0000000373) Calcium and glycolysis mediate multiple bursting m [...] curated model icon download icon
Brannmark2010_InsulinSignalling_Mifamodel (BIOMD0000000343) Mass and information feedbacks through receptor en [...] curated model icon download icon
DallaMan2007_MealModel_GlucoseInsulinSystem (BIOMD0000000379) Meal simulation model of the glucose-insulin syste [...] curated model icon download icon
DeVries2000_PancreaticBetaCells_InsulinSecretion (BIOMD0000000371) Channel sharing in pancreatic beta -cells revisite [...] curated model icon download icon
Ferreira2003_CML_generation2 (BIOMD0000000053) A quantitative model of the generation of N(epsilo [...] curated model icon download icon
Fridlyand2010_GlucoseSensitivity_A (BIOMD0000000348) Glucose sensing in the pancreatic beta cell: a com [...] curated model icon download icon
Fridlyand2010_GlucoseSensitivity_B (BIOMD0000000349) Glucose sensing in the pancreatic beta cell: a com [...] curated model icon download icon
Jiang2007 - GSIS system, Pancreatic Beta Cells (BIOMD0000000239) A kinetic core model of the glucose-stimulated ins [...] curated model icon download icon
Koenig2012 Hepatic Glucose Metabolism (MODEL1204270001) Quantifying the contribution of the liver to gluco [...] non-curated model icon download icon
Koenig2012 Hepatic Glucose Metabolism in Type 2 Diabetes (MODEL1209260000) Kinetic modeling of human hepatic glucose metaboli [...] non-curated model icon download icon
Koschorreck2008_InsulinClearance (BIOMD0000000345) Mathematical modeling and analysis of insulin clea [...] curated model icon download icon
Lenbury2001_InsulinKineticsModel_A (MODEL1201140002) Modeling insulin kinetics: responses to a single o [...] non-curated model icon download icon
Lenbury2001_InsulinKineticsModel_B (MODEL1201140003) Modeling insulin kinetics: responses to a single o [...] non-curated model icon download icon
Noguchi2013 - Insulin dependent glucose metabolism (BIOMD0000000482) The selective control of glycolysis, gluconeogenes [...] curated model icon download icon
Nyman2011_M3Hierarachical_InsulinGlucosedynamics (BIOMD0000000356) A hierarchical whole-body modeling approach elucid [...] curated model icon download icon
Sedaghat2002_InsulinSignalling_noFeedback (BIOMD0000000137) A mathematical model of metabolic insulin signalin [...] curated model icon download icon
Smith2013 - Regulation of Insulin Signalling by Oxidative Stress (BIOMD0000000474) Computational modelling of the regulation of Insul [...] curated model icon download icon
Sturis1991_InsulinGlucoseModel_UltradianOscillation (BIOMD0000000382) Computer model for mechanisms underlying ultradian [...] curated model icon download icon
Tolic2000_InsulinGlucoseFeedback (BIOMD0000000372) Modeling the insulin-glucose feedback system: the [...] curated model icon download icon
Topp2000_BetaCellMass_Diabetes (BIOMD0000000341) A model of beta-cell mass, insulin, and glucose ki [...] curated model icon download icon

disease by infectious agent

Model name Publication Status  
Munz2009 - Zombi Impulsive Killing (MODEL1008060000) When Zombies Attack!: Mathematical modelling of an [...] non-curated model icon download icon
Munz2009 - Zombie SIZRC (MODEL1008060001) When Zombies Attack!: Mathematical modelling of an [...] non-curated model icon download icon
Munz2009 - Zombie SIZRQ (MODEL1008060002) When Zombies Attack!: Mathematical modelling of an [...] non-curated model icon download icon
Munz2009 - Zombie basic SZR (MODEL1009230000) When Zombies Attack!: Mathematical modelling of an [...] non-curated model icon download icon

duodenal ulcer

Model name Publication Status  
Leber2016 - Expanded model of Tfh-Tfr differentiation - Helicobacter pylori infection (BIOMD0000000625) Bistability analyses of CD4+ T follicular helper a [...] curated model icon download icon

fatty liver disease

Model name Publication Status  
Tiemann2011_PhenotypeTransitions (MODEL1112150000) Parameter adaptations during phenotype transitions [...] non-curated model icon download icon

glucocorticoid-remediable aldosteronism

Model name Publication Status  
Komarova2005_PTHaction_OsteoclastOsteoblastCoupling (BIOMD0000000279) Mathematical model of paracrine interactions betwe [...] curated model icon download icon
Lemaire2004 - Role of RANK/RANKL/OPG pathway in bone remodelling process (BIOMD0000000278) Modeling the interactions between osteoblast and o [...] curated model icon download icon

heart disease

Model name Publication Status  
Bucher2011_Atorvastatin_Metabolism (BIOMD0000000328) A systems biology approach to dynamic modeling and [...] curated model icon download icon
Saucerman2006_PKA (BIOMD0000000165) Systems analysis of PKA-mediated phosphorylation g [...] curated model icon download icon
Wang2008_Neonatal_heartfunction (MODEL7814665196) Mathematical model of the neonatal mouse ventricul [...] non-curated model icon download icon

hemochromatosis

Model name Publication Status  
Mitchell2013 - Liver Iron Metabolism (BIOMD0000000498) A computational model of liver iron metabolism. curated model icon download icon

hemophilia B

Model name Publication Status  
Wajima2009_BloodCoagulation_PTtest (BIOMD0000000339) A comprehensive model for the humoral coagulation [...] curated model icon download icon
Wajima2009_BloodCoagulation_aPTTtest (BIOMD0000000338) A comprehensive model for the humoral coagulation [...] curated model icon download icon
Wajima2009_BloodCoagulation_warfarin_heparin (BIOMD0000000340) A comprehensive model for the humoral coagulation [...] curated model icon download icon

human immunodeficiency virus infectious disease

Model name Publication Status  
Aguilera 2014 - HIV latency. Interaction between HIV proteins and immune response (BIOMD0000000573) Studying HIV latency by modeling the interaction b [...] curated model icon download icon
Nelson2000_HIV-1_general_model (MODEL8268650277) A model of HIV-1 pathogenesis that includes an int [...] non-curated model icon download icon
Nelson2000_HIV-1_intracellular_delay (MODEL8102792069) A model of HIV-1 pathogenesis that includes an int [...] non-curated model icon download icon

hyperparathyroidism

Model name Publication Status  
Peterson2010 - Integrated calcium homeostasis and bone remodelling (BIOMD0000000613) A physiologically based mathematical model of inte [...] curated model icon download icon

hypersensitivity reaction type II disease

Model name Publication Status  
Alexander2010_Tcell_Regulation_Sys1 (BIOMD0000000289) Self-tolerance and autoimmunity in a regulatory T [...] curated model icon download icon
Alexander2010_Tcell_Regulation_Sys2 (BIOMD0000000290) Self-tolerance and autoimmunity in a regulatory T [...] curated model icon download icon

hypoparathyroidism

Model name Publication Status  
Peterson2010 - Integrated calcium homeostasis and bone remodelling (BIOMD0000000613) A physiologically based mathematical model of inte [...] curated model icon download icon

immune system disease

Model name Publication Status  
Dunster2014 - WBC Interactions (Model1) (BIOMD0000000616) The resolution of inflammation: a mathematical mod [...] curated model icon download icon

influenza

Model name Publication Status  
Fribourg2014 - Dynamics of viral antagonism and innate immune response (H1N1 influenza A virus - NC/99) (BIOMD0000000529) Model of influenza A virus infection: dynamics of [...] curated model icon download icon
Heldt2012 - Influenza Virus Replication (BIOMD0000000463) Modeling the intracellular dynamics of influenza v [...] curated model icon download icon
Miao2010 - Innate and adaptive immune responses to primary Influenza A Virus infection (BIOMD0000000546) Quantifying the early immune response and adaptive [...] curated model icon download icon

inherited blood coagulation disease

Model name Publication Status  
Hockin1999_BloodCoagulation_VaInactivation (BIOMD0000000365) A model describing the inactivation of factor Va b [...] curated model icon download icon

leishmaniasis

Model name Publication Status  
Mandlik2013 - Synthetic circuit of IPC synthase in Leishmania (MODEL1208030000) Synthetic circuit of inositol phosphorylceramide s [...] non-curated model icon download icon
Mandlik2015 - Tristable genetic circuit of Leishmania (BIOMD0000000584) Regulatory dynamics of network architecture and fu [...] curated model icon download icon
Mol2013 - Immune Signal Transduction in Leishmaniasis (BIOMD0000000477) Immune signal transduction in leishmaniasis from n [...] curated model icon download icon
Mol2013 - Leishmania macrophage signaling network (MODEL1203220000) Signaling networks in Leishmania macrophages decip [...] non-curated model icon download icon

liver disease

Model name Publication Status  
Mueller2015 - Hepatocyte proliferation, T160 phosphorylation of CDK2 (BIOMD0000000568) T160?phosphorylated CDK2 defines threshold for HGF [...] curated model icon download icon
Nikolaev2005_AlbuminBilirubinAdsorption (BIOMD0000000291) Mathematical model of binding of albumin-bilirubin [...] curated model icon download icon

lung cancer

Model name Publication Status  
Tham2008 - PDmodel, Tumour shrinkage by gemcitabine and carboplatin (BIOMD0000000234) A pharmacodynamic model for the time course of tum [...] curated model icon download icon

mature T-cell and NK-cell lymphoma

Model name Publication Status  
Raia2010 - IL13 Signalling MedB1 (BIOMD0000000313) Dynamic mathematical modeling of IL13-induced sign [...] curated model icon download icon

multiple myeloma

Model name Publication Status  
Ayati2010_BoneRemodelingDynamics_NormalCondition (BIOMD0000000401) A mathematical model of bone remodeling dynamics f [...] curated model icon download icon
Ayati2010_BoneRemodelingDynamics_WithTumour (BIOMD0000000402) A mathematical model of bone remodeling dynamics f [...] curated model icon download icon
Ayati2010_BoneRemodelingDynamics_WithTumour+DrugTreatment (BIOMD0000000403) A mathematical model of bone remodeling dynamics f [...] curated model icon download icon

neonatal abstinence syndrome

Model name Publication Status  
Yang2006_Methadone_PKmodel (MODEL1006230040) Population-based analysis of methadone distributio [...] non-curated model icon download icon

non-small cell lung carcinoma

Model name Publication Status  
Bianconi2012 - EGFR and IGF1R pathway in lung cancer (BIOMD0000000427) Computational model of EGFR and IGF1R pathways in [...] curated model icon download icon
Bidkhori2012 - EGFR signalling in NSCLC (BIOMD0000000453) Modeling of tumor progression in NSCLC and intrins [...] curated model icon download icon

ocular albinism

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

osteoarthritis

Model name Publication Status  
Benson2014 - FAAH inhibitors for the treatment of osteoarthritic pain (BIOMD0000000512) A systems pharmacology perspective on the clinical [...] curated model icon download icon
Hui2014 - Age-related changes in articular cartilage (BIOMD0000000560) Oxidative changes and signalling pathways are pivo [...] curated model icon download icon
Komarova2003_BoneRemodeling (BIOMD0000000148) Mathematical model predicts a critical role for os [...] curated model icon download icon

osteoporosis

Model name Publication Status  
Komarova2003_BoneRemodeling (BIOMD0000000148) Mathematical model predicts a critical role for os [...] curated model icon download icon

ovarian disease

Model name Publication Status  
Roblitz2013 - Menstrual Cycle following GnRH analogue administration (BIOMD0000000494) A mathematical model of the human menstrual cycle [...] curated model icon download icon
Stötzel2012 - Bovine estrous cycle, synchronization with prostaglandin F2α (BIOMD0000000481) Advances in modeling of the bovine estrous cycle: [...] curated model icon download icon

pancreatic cancer

Model name Publication Status  
Rateitschak2012 - Interferon-gamma (IFNγ) induced STAT1 signalling (PC_IFNg100) (BIOMD0000000585) Parameter identifiability and sensitivity analysis [...] curated model icon download icon

peptic ulcer disease

Model name Publication Status  
Leber2016 - Expanded model of Tfh-Tfr differentiation - Helicobacter pylori infection (BIOMD0000000625) Bistability analyses of CD4+ T follicular helper a [...] curated model icon download icon

pertussis

Model name Publication Status  
Restif2006 - Whooping cough (BIOMD0000000249) Integrating life history and cross-immunity into t [...] curated model icon download icon
Restif2007 - Vaccination invasion (BIOMD0000000294) Vaccination and the dynamics of immune evasion. curated model icon download icon

polycythemia due to hypoxia

Model name Publication Status  
Hunziker2010_p53_StressSpecificResponse (BIOMD0000000252) Stress-specific response of the p53-Mdm2 feedback [...] curated model icon download icon
Schmierer2010_FIH_Ankyrins (BIOMD0000000300) Hypoxia-dependent sequestration of an oxygen senso [...] curated model icon download icon

primary bacterial infectious disease

Model name Publication Status  
Kaiser2014 - Salmonella persistence after ciprofloxacin treatment (BIOMD0000000527) Cecum lymph node dendritic cells harbor slow-growi [...] curated model icon download icon

prion disease

Model name Publication Status  
Martins2013 - True and apparent inhibition of amyloid fribril formation (BIOMD0000000561) True and apparent inhibition of amyloid fibril for [...] curated model icon download icon

retinal degeneration

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

retinal detachment

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

retinal disease

Model name Publication Status  
Clarke2000 - One-hit model of cell death in neuronal degenerations (BIOMD0000000538) A one-hit model of cell death in inherited neurona [...] curated model icon download icon

rheumatoid arthritis

Model name Publication Status  
Baker2013 - Cytokine Mediated Inflammation in Rheumatoid Arthritis (BIOMD0000000550) Mathematical modelling of cytokine-mediated inflam [...] curated model icon download icon
Baker2013 - Cytokine Mediated Inflammation in Rheumatoid Arthritis - Age Dependent (BIOMD0000000549) Mathematical modelling of cytokine-mediated inflam [...] curated model icon download icon

swine influenza

Model name Publication Status  
Fribourg2014 - Dynamics of viral antagonism and innate immune response (H1N1 influenza A virus - Cal/09) (BIOMD0000000528) Model of influenza A virus infection: dynamics of [...] curated model icon download icon

tauopathy

Model name Publication Status  
Yuraszeck2010 - Vulnerabilities in the Tau Network in Tau Pathophysiology (BIOMD0000000542) Vulnerabilities in the tau network and the role of [...] curated model icon download icon

tuberculosis

Model name Publication Status  
Palsson2013 - Fully-integrated immune response model (FIRM) (BIOMD0000000608) The development of a fully-integrated immune respo [...] curated model icon download icon

type 1 diabetes mellitus

Model name Publication Status  
Maree2006_DuCa_Type1DiabetesModel (BIOMD0000000381) Modelling the onset of Type 1 diabetes: can impair [...] curated model icon download icon

type 2 diabetes mellitus

Model name Publication Status  
Brännmark2013 - Insulin signalling in human adipocytes (diabetic condition) (BIOMD0000000449) Insulin signaling in type 2 diabetes: experimental [...] curated model icon download icon
Brännmark2013 - Insulin signalling in human adipocytes (normal condition) (BIOMD0000000448) Insulin signaling in type 2 diabetes: experimental [...] curated model icon download icon
Palmer2014 - Effect of IL-1β-Blocking therapies in T2DM - Disease Condition (BIOMD0000000620) Effects of IL-1β-Blocking Therapies in Type 2 Diab [...] curated model icon download icon
Palmer2014 - Effect of IL-1β-Blocking therapies in T2DM - Healthy Condition (BIOMD0000000621) Effects of IL-1β-Blocking Therapies in Type 2 Diab [...] curated model icon download icon
Silber2007_IntravenousGlucose_IntegratedGlucoseInsulinModel (MODEL1112110004) An integrated model for glucose and insulin regula [...] non-curated model icon download icon

See also: International Classification of Diseases

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