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Benzoxazinoid biosynthesis - Zea mays


Model information
Identifier: BMID000000132162
Format: SBML L3 V1 (Layout)
Project: path2models
Categories: metabolic
Submission: 19 May 2012 00:20:50 UTC
Last modified: 10 Dec 2012 14:09:18 UTC
Published: 19 May 2012 23:49:21 UTC
occursIn Zea mays Taxonomy
isDerivedFrom Benzoxazinoid biosynthesis KEGG Pathway
Model of “Benzoxazinoid biosynthesis” in “Zea mays (maize)”
Benzoxazinoids (hydroxamic acids) are plant secondary metabolites that serve as important factors for host resistance against microbial pathogens and insects and for allelopathic effects. They are found in grass family and some eudicot families. The predominant benzoxazinoids are DIBOA and its 7-methoxy derivative DIMBOA, which are stored as glucosides in vacuoles. In maize, benzoxazinoid biosynthesis branches off from tryptophan biosynthesis at indole-3-glycerol phosphate, which is converted to indole by indole-3-glycerol phosphate lyase, BX1. Subsequently four cytochrome P450 monooxygenases (BX2-BX5) catalyze the introduction of four oxygen atoms into the indole moiety, yielding DIBOA. After glucosylation by UDP-glucosyltransferase (BX8/BX9), the glucoside is further modified by hydroxylation and O-methylation at C-7 to form DIMBOA-glucoside.

Graphical representation of 'Benzoxazinoid biosynthesis (Zea mays (maize))'
(PNG image hosted by the Kyoto Encyclopedia of Genes and Genomes, KEGG).
This model has been automatically generated by KEGGtranslator V2.2.0 (KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats. Wrzodek C, Dräger A, Zell A. Bioinformatics . 2011, 27 :2314-2315) using information coming from the KEGG PATHWAY Database ( original pathway ).
The missing kinetic equations were added by SBMLsqueezer .
This model has been produced by the path2models project, it is currently hosted on BioModels Database and identified by: BMID000000132162 .
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.