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BIOMD0000000483 - Cao2008 - Network of a toggle switch

 

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Reference Publication
Publication ID: 18373871
Cao Y, Liang J.
Optimal enumeration of state space of finitely buffered stochastic molecular networks and exact computation of steady state landscape probability.
BMC Syst Biol 2008; 2: 30
Shanghai Center for Systems Biomedicine (SCSB), Shanghai Jiao Tong University, Shanghai, 200240, China. yfcao@sjtu.edu.cn  [more]
Model
Original Model: Toggle Switch
Submitter: Youfang Cao
Submission ID: MODEL1308080008
Submission Date: 08 Aug 2013 20:34:23 UTC
Last Modification Date: 04 Apr 2014 15:49:20 UTC
Creation Date: 23 Sep 2013 11:35:17 UTC
Encoders:  Vijayalakshmi Chelliah
   Youfang Cao
set #1
bqbiol:hasProperty Mathematical Modelling Ontology MAMO_0000046
set #2
bqbiol:hasTaxon Taxonomy cellular organisms
set #3
bqbiol:isVersionOf Gene Ontology regulation of gene expression
Gene Ontology molecular_function
Notes
Model
Publication ID: 18373871 Submission Date: 08 Aug 2013 20:34:23 UTC Last Modification Date: 04 Apr 2014 15:49:20 UTC Creation Date: 23 Sep 2013 11:35:17 UTC
Mathematical expressions
Reactions
re2 re1 re12 re11
re13 re5 re7 re14
Physical entities
Compartments Species
default Pa Pb Da
Db BDa BDb
ESA ESB  
Global parameters
da db sa sb
ba bb ua ub
Reactions (8)
 
 re2 [ESA] → [Pa];   {Da} , {Da}
 
 re1 [ESB] → [Pb];   {Db} , {Db}
 
 re12 [Pa] → [ESA];   {Pa}
 
 re11 [Pb] → [ESB];   {Pb}
 
 re13 2.0 × [Pa] + [Db] → [BDb];   {Pa} , {Db}
 
 re5 2.0 × [Pb] + [Da] → [BDa];   {Pb} , {Da}
 
 re7 [BDa] → [Da] + 2.0 × [Pb];   {BDa}
 
 re14 [BDb] → 2.0 × [Pa] + [Db];   {BDb}
 
  Spatial dimensions: 3.0  Compartment size: 1.0
 
 Pa
Compartment: default
Initial amount: 0.0
 
 Pb
Compartment: default
Initial amount: 0.0
 
 Da
Compartment: default
Initial amount: 0.0
 
 Db
Compartment: default
Initial amount: 0.0
 
 BDa
Compartment: default
Initial amount: 0.0
 
 BDb
Compartment: default
Initial amount: 0.0
 
 ESA
Compartment: default
Initial amount: 0.0
 
 ESB
Compartment: default
Initial amount: 0.0
 
Global Parameters (8)
 
   da
Value: 1.0
Constant
 
   db
Value: 1.0
Constant
 
   sa
Value: 100.0
Constant
 
   sb
Value: 100.0
Constant
 
   ba
Value: 1.0E-5
Constant
 
   bb
Value: 1.0E-5
Constant
 
   ua
Value: 0.1
Constant
 
   ub
Value: 0.1
Constant
 
Representative curation result(s)
Representative curation result(s) of BIOMD0000000483

Curator's comment: (updated: 23 Sep 2013 12:34:33 BST)

There are two networks that is described in the paper. 1. Network of self-regulating gene, 2) Toggle switch network. This model correspond to the toggle switch network. There is no figure in the paper to be reproduced as curation figure.

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